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International Journal of Oncology, ISSN 1019-6439, 04/2017, Volume 50, Issue 4, pp. 1372 - 1382
Regulation of rRNA transcription is an important factor for control of cell proliferation. We previously found that the JmjC domain-containing demethylase... 
Zf-CXXC | SF-KDM2A | KDM2A | Nucleolus | H4K20 methylation | RRNA transcription | zf-CXXC | METHYLATION | I TRANSCRIPTION | LUNG-CANCER | TRIMETHYLATION | rRNA transcription | DOMAIN-CONTAINING PROTEINS | ONCOLOGY | HISTONE DEMETHYLASE KDM2A | GASTRIC-CANCER | nucleolus | S-KDM2A | STARVATION | CPG ISLANDS | POLYMERASE-I
Journal Article
Oncotarget, ISSN 1949-2553, 07/2019, Volume 10, Issue 46, p. 4743
Triple-negative breast cancer (TNBC) is very aggressive and lacks specific therapeutic targets. Ribosome RNAs (rRNAs) are central components of ribosomes and... 
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 6/2019, Volume 456, Issue 1, pp. 95 - 104
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 07/2013, Volume 379, Issue 1-2, pp. 115 - 122
Journal Article
PLOS GENETICS, ISSN 1553-7404, 08/2017, Volume 13, Issue 8
KDM2A is a histone demethylase associated with transcriptional silencing, however very little is known about its in vivo role in development and disease. Here... 
PROTEIN | HISTONE DEMETHYLASE KDM2A | REPAIR PATHWAY | DNA | SEQUENCE | GENETICS & HEREDITY | GENE-EXPRESSION | TUMOR | CANCER | TUMORIGENESIS | GENOME
Journal Article
Oncotarget, ISSN 1949-2553, 2018, Volume 9, Issue 22, pp. 15915 - 15930
Lysine demethylase 2A (KDM2A) functions in transcription as a demethylase of lysine 36 on histone H3. Herein, we characterise a role for KDM2A in the DNA... 
Ubiquitin | KDM2A | Genome stability | 53BP1 | DNA double strand break repair
Journal Article
Genes, chromosomes & cancer, ISSN 1045-2257, 1/2017, Volume 56, Issue 1, pp. 42 - 50
Ossifying fibromyxoid tumor (OFMT) is an uncommon mesenchymal neoplasm of uncertain differentiation and intermediate malignant potential. Recurrent gene... 
ossifying fibromyxoid tumor | endometrial stromal sarcoma | WWTR1 | CREBBP | KDM2A | BCORL1
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 5496 - 14
The lysine-specific demethylase 2A gene (KDM2A) is ubiquitously expressed and its transcripts consist of several alternatively spliced forms, including KDM2A... 
METHYLATION | KDM2A | REPLICATION | GENE | CHROMATIN | ORC BINDING | MULTIDISCIPLINARY SCIENCES | RIBOSOMAL-RNA TRANSCRIPTION | KERATINOCYTES | MAINTAINS | HISTONE | Keratinocytes | Alternative splicing | Chromatin | Lysine | Mitosis | CpG islands
Journal Article
Nucleus, ISSN 1949-1034, 12/2018, Volume 9, Issue 1, pp. 431 - 441
Journal Article
Structure, ISSN 0969-2126, 09/2018, Volume 26, Issue 9, pp. 1226 - 1236.e3
Skp1-Cul1-F-box (SCF) E3 ligases constitute the largest and best-characterized family of the multisubunit E3 ligases with important cellular functions and... 
X-ray crystallography | E3 ligases | phage display | ubiquitination | ubiquitin variants | Fbl10 | Fbl11 | structural biology | Kdm2b | Kdm2a | SYSTEM | BIOPHYSICS | RING | BIOCHEMISTRY & MOLECULAR BIOLOGY | SEQUENCE | E3 LIGASES | BINDING | MODULATION | DISCOVERY | SNAIL | CELL BIOLOGY | Ubiquitin | Structure | Ligases | Analysis | Crystals
Journal Article
by Gao, RT and Dong, R and Du, J and Ma, P and Wang, SL and Fan, ZP
MOLECULAR AND CELLULAR BIOCHEMISTRY, ISSN 0300-8177, 07/2013, Volume 379, Issue 1-2, pp. 115 - 122
Mesenchymal stem cells (MSCs) are a reliable resource for tissue regeneration; although, the molecular mechanisms of their differentiation and proliferation... 
Cell proliferation | p27Kip1 | KDM2A | SWINE | REGENERATION | VALIDATION | F-BOX PROTEINS | Stem cells from apical papilla | HUMAN PERIODONTAL-LIGAMENT | FBXL11 | FAMILY | CELL BIOLOGY | p15(INK4B) | DIFFERENTIATION | DEPENDENT KINASES | JMJC
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 9/2017, Volume 74, Issue 18, pp. 3305 - 3315
Arginine methylation of histones is one mechanism of epigenetic regulation in eukaryotic cells. Methylarginines can also be found in non-histone proteins... 
Biomedicine, general | Biochemistry, general | KDM6B | KDM3A | KDM5C | KDM2A | KDM4E | Liquid chromatography–tandem mass spectrometry | Histone modifications | Cell Biology | PHF8 | Life Sciences | Post-translational modifications | KMT | Life Sciences, general | KDM | KDM7B | YEAST PROTEINS | PEPTIDYLARGININE DEIMINASES | HUMAN-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | Liquid chromatography-tandem mass spectrometry | POSTTRANSLATIONAL MODIFICATIONS | SACCHAROMYCES-CEREVISIAE | NONHISTONE PROTEINS | MASS-SPECTROMETRY | CELL BIOLOGY | LYSYL-HYDROXYLATION | LUNG ADENOCARCINOMA | PROTEOMIC ANALYSIS | Hydrolases - metabolism | Histone Demethylases - metabolism | Animals | Humans | Histones - metabolism | Methylation | Arginine - analogs & derivatives | Arginine - metabolism | Protein-Arginine Deiminases | Arginine - analysis | Protein-Arginine N-Methyltransferases - metabolism | Post-translational modification | Epigenetic inheritance | Environmental health | Jewish schools | Liquid chromatography | DNA binding proteins | Methyltransferases | Arginine | Lysine | Analysis | Histones | Research institutes | Molecular biology | Mass spectrometry | Enzymes | Regulations | Residues | Chromatin | Mass spectroscopy | Iron | Environmental factors | Arginine deiminase | Proteins | Demethylation | Signaling | Protein-arginine deiminase | Epigenetics | DNA methylation | Acetylation | a-Ketoglutaric acid | Index Medicus
Journal Article
Journal Article
Artificial Cells, Nanomedicine, and Biotechnology, ISSN 2169-1401, 12/2019, Volume 47, Issue 1, pp. 2891 - 2899
JHDM1A participates in cancer development via demethylate dimethyl histone H3 lysine 36 (H3K36me2). p300 is an intrinsic acetyltransferase. This study explored... 
p300 | H3K36me2 | JHDM1A | Osteosarcoma | puma | LUNG | METHYLATION | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | CELL-PROLIFERATION | CANCER | p21 | HISTONE DEMETHYLASE KDM2A | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GROWTH | EXPRESSION | PROGRESSION
Journal Article
International Journal of Biological Markers, ISSN 0393-6155, 2018, Volume 33, Issue 4, pp. 407 - 414
Objective: Lysine-specific demethylase 2A (KDM2A), a specific H3K36me1/2 demethylase, has been reported to be closely associated with several types of cancer.... 
Demethylase | KDM2A | Cyclin D1 | Colorectal adenocarcinoma | METHYLATION | GENE | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | cyclin D1 | demethylase | HISTONE MODIFICATIONS | POLYCOMB | PROGRESSION
Journal Article
Nucleic acids research, ISSN 0305-1048, 02/2017, Volume 45, Issue 3, pp. 1114 - 1129
Journal Article