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Steroids, ISSN 0039-128X, 03/2019, Volume 143, pp. 73 - 79
Human aldo-keto reductase AKR1C3 (type 2 3α-hydroxysteroid dehydrogenase/type 5 17β-hydroxysteroid dehydrogenase) is involved in testosterone and estrogen... 
AKR | AKR1C3 | Specificity | Monoclonal antibody | 10B10 | Aldo-keto reductase | HUMAN PROSTATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROGESTERONE ACTION | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | PR-104 | ENDOCRINOLOGY & METABOLISM | REVEALS ROLES | MOLECULAR-CLONING | ALPHA-HYDROXYSTEROID DEHYDROGENASE | INHIBITORS | EXPRESSION | PRE-RECEPTOR REGULATION
Journal Article
Journal Article
Steroids, ISSN 0039-128X, 2004, Volume 69, Issue 13, pp. 795 - 801
Journal Article
Journal Article
The Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 10/2018, Volume 183, p. 192
The progression of castration resistant prostate cancer (CRPC) is driven by the intratumoral conversion of adrenal androgen precursors to potent androgens. The... 
Androgens | Castration | Computer applications | Oxidation | Androstenedione | Prostate cancer | Prostate | Substrates | Aldo-keto reductase | Tumors
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2017, Volume 139, pp. 936 - 946
Journal Article
Journal Article
Journal Article
Chemometrics and Intelligent Laboratory Systems, ISSN 0169-7439, 12/2014, Volume 139, pp. 132 - 138
Journal Article
Journal Article
Journal Article
Endocrine-Related Cancer, ISSN 1351-0088, 03/2006, Volume 13, Issue 1, pp. 169 - 180
Type 2 3α-hydroxysteroid dehydrogenase (3α-HSD) is a multi-functional enzyme that possesses 3α-, 17β- and 20α-HSD, as well as prostaglandin (PG) F synthase... 
KETO REDUCTASE AKR1C3 | HYDROXYSTEROID DEHYDROGENASE | LOCALIZATION | LNCAP CELL-PROLIFERATION | WALLABY POUCH YOUNG | 3-BETA-HYDROXYSTEROID DEHYDROGENASE | ONCOLOGY | PPAR-GAMMA LIGANDS | GROWTH | ENDOCRINOLOGY & METABOLISM | DIFFERENTIATION | CANCER
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 2015, Volume 69, pp. 317 - 325
Abstract Aldo-keto reductase 1C3 (AKR1C3), one member of the aldo-keto reductase superfamily, is involved in a variety of cancers. Recently, AKR1C3 has been... 
Internal Medicine | Medical Education | AKR1C3 | PTEN/Akt | Human breast cancer | DOX resistance | PTEN loss | MEDICINE, RESEARCH & EXPERIMENTAL | TUMOR-CELLS | STEROID-HORMONE | SEX STEROIDS | 5 17-BETA-HYDROXYSTEROID-DEHYDROGENASE AKR1C3 | REVEALS ROLES | PROGNOSTIC MARKER | PHARMACOLOGY & PHARMACY | MOLECULAR-CLONING | ANTICANCER DRUGS | ALPHA-HYDROXYSTEROID DEHYDROGENASE | IN-SITU | Doxorubicin - therapeutic use | Apoptosis - drug effects | Humans | RNA, Messenger - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Breast Neoplasms - enzymology | Transfection | MCF-7 Cells | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Chromones - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Cell Survival - drug effects | Green Fluorescent Proteins - metabolism | RNA, Messenger - genetics | Morpholines - pharmacology | PTEN Phosphohydrolase - metabolism | Enzyme Activation - drug effects | Breast Neoplasms - drug therapy | Blotting, Western | Hydroxyprostaglandin Dehydrogenases - genetics | Breast Neoplasms - genetics | Signal Transduction - drug effects | Aldo-Keto Reductase Family 1 Member C3 | Breast Neoplasms - pathology | Protein Kinase Inhibitors - pharmacology | 3-Hydroxysteroid Dehydrogenases - genetics | Doxorubicin - pharmacology | Drug Resistance, Neoplasm - drug effects | Anthracyclines | Breast cancer
Journal Article