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1. Full Text Blood -hydroxybutyrate vs. urine acetoacetate testing for the prevention and management of ketoacidosis in Type1 diabetes: a systematic review
by Klocker, AA and Phelan, H and Twigg, SM and Craig, ME
DIABETIC MEDICINE, ISSN 0742-3071, 07/2013, Volume 30, Issue 7, pp. 818 - 824
Abstact Aim Diabetic ketoacidosis is a life-threatening complication of Type1 diabetes. Blood -hydroxybutyrate testing is now widely available as an... 
KETONE-BODIES | ENDOCRINOLOGY & METABOLISM | CHILDREN
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2. Full Text The 'epileptic diet'- ketogenic and/or slow release of glucose intervention: A review
by Qi, Xin and Tester, Richard F
Clinical nutrition (Edinburgh, Scotland), ISSN 0261-5614, 06/2019
The ketogenic diet is high in fat content, adequate with respect to protein but low in carbohydrate and designed to provide brain energy as ketone bodies... 
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3. Full Text β-Hydroxybutyrate
: A S
by Newman, John C and Verdin, Eric
Annual review of nutrition, ISSN 0199-9885, 8/2017, Volume 37, pp. 51 - 76
Various mechanisms in the mammalian body provide resilience against food deprivation and dietary stress. The ketone body β-hydroxybutyrate (BHB) is synthesized... 
metabolism | ketone bodies | fasting | aging | epigenetics
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4. Inborn errors of ketone body metabolism
by Fukao, Toshiyuki
2007, Protein epidemiology : understanding human diseases at the level of protein structure and function
Proteins | Ketone Bodies | Protein Conformation | metabolism
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5. Inborn errors of ketone body metabolism
by Fukao, Toshiyuki
2007, Protein epidemiology : understanding human diseases at the level of protein structure and function
Proteins | Ketone Bodies | Protein Conformation | metabolism
Web Resource
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6. Full Text Effects of a dietary ketone ester on hippocampal glycolytic and TCA cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer’s disease
by Pawlosky, Robert J and Kemper, Martin F and Kashiwaya, Yoshihero and King, M. Todd and Mattson, Mark P and Veech, Richard L
Journal of neurochemistry, ISSN 0022-3042, 4/2017, Volume 141, Issue 2, pp. 195 - 207
In patients with Alzheimer’s disease (AD) and in a triple transgenic (3xTgAD) mouse model of AD low glucose metabolism in the brain precedes loss of memory and... 
ketone bodies | cellular energetics | hippocampus | mitochondria | glycolysis
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7. Full Text Ketogenic Diets and Exercise Performance
by Harvey, Kristin L and Holcomb, Lola E and Kolwicz, Stephen C
Nutrients, ISSN 2072-6643, 09/2019, Volume 11, Issue 10, p. 2296
The ketogenic diet (KD) has gained a resurgence in popularity due to its purported reputation for fighting obesity. The KD has also acquired attention as an... 
ketone supplements | ketone bodies | metabolism | ketosis | endurance exercise | obesity
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8. Empagliflozin, an SGLT2 Inhibitor, Reduced the Mortality Rate after Acute Myocardial Infarction with Modification of Cardiac Metabolomes and Antioxidants in Diabetic Rats
by Oshima, Hiroto and Miki, Takayuki and Kuno, Atsushi and Mizuno, Masashi and Sato, Tatsuya and Tanno, Masaya and Yano, Toshiyuki and Nakata, Kei and Kimura, Yukishige and Abe, Koki and Ohwada, Wataru and Miura, Tetsuji
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 03/2019, Volume 368, Issue 3, pp. 524 - 534
The mechanism by which SGLT2 inhibitors reduce cardiac events in diabetic patients remains unclear. Here, we examined the effects of an SGLT2 inhibitor on the... 
SHIFT | OXIDATIVE STRESS | BETA-HYDROXYBUTYRATE | KETONE-BODIES | HEART-FAILURE | RISK | PHARMACOLOGY & PHARMACY | MICE | OUTCOMES
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9. Full Text 2477-PUB: Blood Beta Hydroxybutyrate Levels in Adult Patients Presenting to Emergency Department
by DEPCZYNSKI, BARBARA and LEE, ALEXANDRA T and VARNDELL, WAYNE F and CHIEW, ANGELA L
Diabetes, ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 2477
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10. Full Text Influencia del aceite de coco en enfermos de alzhéimer a nivel cognitive
by Ortí, José Enrique de la Rubia and Álvarez, Carmen Sánchez and Sabater, Pablo Selvi and Cayo, Alma María Bueno and Castillo, Sandra Sancho and Rochina, Mariano Julián and Yang, Iván Hu
Nutricion Hospitalaria, ISSN 0212-1611, 2017, Volume 34, Issue 2, pp. 352 - 356
Alzheimer’s disease | Coconut oil | Ketone bodies | Triglycerides
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11. Full Text El β-hidroxi-β-metilbutirato (HMB) como suplemento nutricional (I): metabolismo y toxicidad
by Manjarrez-Montes-de-Oca, Rafael and Torres-Vaca, Mateo and González-Gallego, Javier and Alvear-Ordenes, Ildefonso
Nutricion Hospitalaria, ISSN 0212-1611, 11/2015, Volume 31, Issue 2, pp. 590 - 596
Toxicity | Ketone Bodies | Leucine | Metabolism | Cholesterol
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12. Full Text Metabolic regulation of gene expression through histone acylations
by Sabari, Benjamin R and Zhang, Di and Allis, C. David and Zhao, Yingming
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 02/2017, Volume 18, Issue 2, pp. 90 - 101
Eight types of short-chain Lys acylations have recently been identified on histones: propionylation, butyrylation, 2-hydroxyisobutyrylation, succinylation,... 
BETA-HYDROXYBUTYRATE | IN-VITRO | TANDEM PHD FINGER | KETONE-BODIES | CHROMATIN | ACETYLATION | CHAIN FATTY-ACIDS | AF9 YEATS DOMAIN | TRANSCRIPTION | POSTTRANSLATIONAL MODIFICATIONS | CELL BIOLOGY | Histones - chemistry | Spermatogenesis | Humans | Gene Expression Regulation | Stress, Physiological | Male | Acetyl Coenzyme A - metabolism | Fatty Acids, Volatile - metabolism | Animals | Histones - genetics | Protein Domains | Lysine - metabolism | Protein Processing, Post-Translational | Histones - metabolism | Acyl Coenzyme A - metabolism | Acylation | Cell metabolism | Histones | Genetic aspects | Gene expression | Properties | Health aspects
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13. Full Text Associations between ketone bodies and fasting plasma glucose in individuals with post-pancreatitis prediabetes
by Bharmal, Sakina H and Pendharkar, Sayali A and Singh, Ruma G and Cameron-Smith, David and Petrov, Maxim S
Archives of Physiology and Biochemistry, ISSN 1381-3455, 2018, pp. 1 - 12
Levels of ketone bodies are altered in both acute pancreatitis and type 1 and type 2 diabetes. However, the role of ketone bodies in the pathogenesis of... 
cytokines | Ketone bodies | insulin | post-pancreatitis prediabetes | acute pancreatitis
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14. Full Text Aceite de coco: Tratamiento alternativo no farmacológico frente a la enfermedad de Alzheimer
by Yang, Iván Hu and de La Rubia Ortí, José Enrique and Sabater, Pablo Selvi and Castillo, Sandra Sancho and Rochina, Mariano Julián and Ramón, Noemí Manresa and Montoya-Castilla, E Inmaculada
Nutricion Hospitalaria, ISSN 0212-1611, 2015, Volume 32, Issue 6, pp. 2822 - 2827
Alzheimer’s disease | Coconut oil | Ketone bodies | Triglycerides
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15. Full Text Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
by Tadahiro Shimazu and Matthew D. Hirschey and John Newman and Wenjuan He and Kotaro Shirakawa and Natacha Le Moan and Carrie A. Grueter and Hyungwook Lim and Laura R. Saunders and Robert D. Stevens and Christopher B. Newgard and Robert V. Farese and Rafael de Cabo and Scott Ulrich and Katerina Akassoglou and Eric Verdin
Science, ISSN 0036-8075, 1/2013, Volume 339, Issue 6116, pp. 211 - 214
Concentrations of acetyl-coenzyme A and nicotinamide adenine dinucleotide (NAD + ) affect histone acetylation and thereby couple cellular metabolic status and... 
Oxidative stress | Kidneys | Fasting | HEK293 cells | Pumps | Genes | REPORTS | Histones | Immunoblotting | Acetylation | T tests | CELLS | KETONE-BODIES | METABOLISM | ACETYLATION | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | EXPRESSION | Metallothionein - metabolism | Caloric Restriction | Humans | Transcriptional Activation | Histone Deacetylase Inhibitors - blood | Kidney - metabolism | HEK293 Cells | Transcription, Genetic | Superoxide Dismutase - metabolism | Promoter Regions, Genetic | Kidney - drug effects | Histone Deacetylases - genetics | 3-Hydroxybutyric Acid - blood | Mice, Inbred C57BL | Oxidative Stress - genetics | Histone Deacetylases - metabolism | Forkhead Transcription Factors - genetics | Catalase - metabolism | Animals | Metallothionein - genetics | 3-Hydroxybutyric Acid - metabolism | Histone Deacetylase Inhibitors - pharmacology | Mice | RNA, Small Interfering | Histones - metabolism | 3-Hydroxybutyric Acid - pharmacology | Forkhead Box Protein O3 | Histone Deacetylase Inhibitors - metabolism | Lipid Peroxidation | Stresses | Stress concentration | Poisons | Fatty acids
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16. Full Text Cancer as a metabolic disease: Implications for novel therapeutics
by Seyfried, Thomas N and Flores, Roberto E and Poff, Angela M and D'Agostino, Dominic P
Carcinogenesis, ISSN 0143-3334, 2014, Volume 35, Issue 3, pp. 515 - 527
Emerging evidence indicates that cancer is primarily a metabolic disease involving disturbances in energy production through respiration and fermentation. The... 
OXIDATIVE-PHOSPHORYLATION | KETONE-BODIES | RESPIRATORY IMPAIRMENT | ONCOLOGY | HUMAN CYTOMEGALOVIRUS | RESTRICTED KETOGENIC DIET | MITOCHONDRIAL DYSFUNCTION | CYTOPLASMIC SUPPRESSION | ENERGY-METABOLISM | ADENINE-NUCLEOTIDE TRANSLOCASE | GLUTAMINE-METABOLISM | Neoplasms - metabolism | Genes, p53 | Neoplasms - therapy | Energy Metabolism | Neoplasms - genetics | Humans | Mitochondria - metabolism | Mutation | Genes, ras | Review
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17. Full Text The Failing Heart Relies on Ketone Bodies as a Fuel
by Aubert, Gregory and Martin, Ola J and Horton, Julie L and Lai, Ling and Vega, Rick B and Leone, Teresa C and Koves, Timothy and Gardell, Stephen J and Krüger, Marcus and Hoppel, Charles L and Lewandowski, E. Douglas and Crawford, Peter A and Muoio, Deborah M and Kelly, Daniel P
Circulation, ISSN 0009-7322, 02/2016, Volume 133, Issue 8, pp. 698 - 705
Background Significant evidence indicates that the failing heart is energy starved. During the development of heart failure, the capacity of the heart to... 
molecular biology | heart failure | metabolism | fatty acids | hypertrophy | PRESSURE-OVERLOAD | CARDIAC & CARDIOVASCULAR SYSTEMS | FAILURE SEVERITY | PALMITATE OXIDATION | MYOCARDIAL SUBSTRATE METABOLISM | DILATED CARDIOMYOPATHY | SKELETAL-MUSCLE | FATTY-ACID OXIDATION | CARDIAC-HYPERTROPHY | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | ENERGY-METABOLISM | Animals | Diet, Ketogenic - methods | Ketone Bodies - metabolism | Mice, Inbred C57BL | Female | Gene Expression Profiling - methods | Heart Failure - metabolism | Mice | Heart Failure - diet therapy | Heart Failure - pathology | Fatty Acids - metabolism | Heart failure | ATP synthesis | Ketone bodies | Research | Analysis | fatty acid
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18. Full Text Ketone bodies as signaling metabolites
by Newman, John C and Verdin, Eric
Trends in Endocrinology & Metabolism, ISSN 1043-2760, 2013, Volume 25, Issue 1, pp. 42 - 52
Highlights • Ketone bodies have signaling functions as well as being a mobile source of cellular energy. • Ketone bodies inhibit histone deacetylases and... 
Endocrinology & Metabolism | acetylation | longevity | calorie restriction | epigenetics | HDAC | Epigenetics | Acetylation | Longevity | Calorie restriction | LIFE-SPAN | HISTONE DEACETYLASE INHIBITOR | D-BETA-HYDROXYBUTYRATE | MITOCHONDRIAL 3-HYDROXY-3-METHYLGLUTARYL-COA SYNTHASE | CARBOHYDRATE KETOGENIC DIET | HEMORRHAGIC-SHOCK | CHAIN FATTY-ACIDS | ENDOCRINOLOGY & METABOLISM | CONVENTIONAL RINGERS SOLUTION | HEPATIC LIPID-METABOLISM | Monocarboxylic Acid Transporters - metabolism | Animals | Aging - physiology | Caloric Restriction | 3-Hydroxybutyric Acid - metabolism | Humans | Ketone Bodies - metabolism | Histone Deacetylase Inhibitors - pharmacology | Histone Deacetylases - metabolism | Signal Transduction - physiology | Metabolites
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19. Full Text Intergenerational Metabolic Syndrome and Neuronal Network Hyperexcitability in Autism
by Rivell, Aileen and Mattson, Mark P
Trends in Neurosciences, ISSN 0166-2236, 10/2019, Volume 42, Issue 10, pp. 709 - 726
We review evidence that suggests a role for excessive consumption of energy-dense foods, particularly fructose, and consequent obesity and insulin resistance... 
high fructose corn syrup | acetylome | GABA | mTOR | ketone bodies | autism spectrum disorder | diabetes | obesity | sociality
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