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JAMA Neurology, ISSN 2168-6149, 12/2014, Volume 71, Issue 12, pp. 1535 - 1539
IMPORTANCE: Mutations in SNCA, LRRK2, VPS35, EIF4G1, and DNAJC13 have been implicated in late-onset familial parkinsonism. However, the estimated disease... 
LRRK2 G2019S | RETROMER | DEMENTIA | GENETICS | JEWS | KIN-COHORT | ALPHA-SYNUCLEIN | MUTATIONS | CLINICAL NEUROLOGY | Parkinsonian Disorders - genetics | Penetrance | Humans | Age of Onset
Journal Article
Movement Disorders, ISSN 0885-3185, 10/2017, Volume 32, Issue 10, pp. 1432 - 1438
Journal Article
Journal Article
2017, ISBN 9780128018934, Volume 144
Huntington disease (HD) is caused by a CAG trinucleotide expansion in the gene. We now have the power to predict age-at-onset from subject-specific features... 
Age-at-onset | Penetrance | Measurement error | Diagnosis definitions | Kin-cohort study | Prediction
Book Chapter
Journal of the American Statistical Association, ISSN 0162-1459, 12/2012, Volume 107, Issue 500, pp. 1324 - 1338
This work presents methods for estimating genotype-specific distributions from genetic epidemiology studies where the event times are subject to right... 
Censored data | Huntington’s disease | Finite mixture model | Quantitative trait locus | Kin-cohort design
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 10/2005, Volume 97, Issue 20, pp. 1507 - 1515
Journal Article
Cancer Epidemiology Biomarkers & Prevention, ISSN 1055-9965, 02/2006, Volume 15, Issue 2, pp. 312 - 314
Journal Article
Biometrika, ISSN 0006-3444, 08/2015, Volume 102, Issue 3, pp. 515 - 532
With the discovery of an increasing number of causal genes for complex human disorders, it is crucial to assess the genetic risk of disease onset for... 
Semiparametric efficiency | Sieve maximum likelihood estimation | Empirical process | Parkinson's disease | Mixture distribution | REGRESSION | G2019S MUTATION | LRRK2 | PHENOTYPE | STATISTICS & PROBABILITY | INFERENCE | QUANTITATIVE TRAIT LOCI | PENETRANCE | BIOLOGY | MATHEMATICAL & COMPUTATIONAL BIOLOGY | KIN-COHORT | ASHKENAZI JEWS | PARKINSON-DISEASE
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 08/2002, Volume 94, Issue 16, pp. 1221 - 1226
Journal Article
Journal Article
Electronic Journal of Statistics, ISSN 1935-7524, 2017, Volume 11, Issue 1, pp. 1928 - 1948
We propose methods to estimate the distribution functions for multiple populations from mixture data that are only known to belong to a specific population... 
Quadratic inference function | Bootstrap | Huntington’s disease | Efficiency | Familial correlation | Mixed samples | PENETRANCE | efficiency | familial correlation | quadratic inference function | DISEASE | mixed samples | KIN-COHORT | STATISTICS & PROBABILITY | Huntington's disease | ONSET | AGE
Journal Article
Journal Article
Statistics in Medicine, ISSN 0277-6715, 04/2014, Volume 33, Issue 8, pp. 1369 - 1382
Huntington's disease (HD) is a neurodegenerative disorder with a dominant genetic mode of inheritance caused by an expansion of CAG repeats on chromosome 4.... 
partially linear model | mixture | age at onset | chronic disease | varying‐coefficient model | Varying-coefficient model | Age at onset | Partially linear model | Chronic disease | Mixture | MEDICINE, RESEARCH & EXPERIMENTAL | varying-coefficient model | MEDICAL INFORMATICS |