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Journal Article
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2015, Volume 23, Issue 13, pp. 3269 - 3277
[Display omitted] Protein kinase C theta (PKCθ) plays a critical role in T cell signaling and has therapeutic potential for T cell-mediated diseases such as... 
Protein kinase C theta (PKCθ) | CYP3A4 time-dependent inhibition (TDI) | P-glycoprotein (P-gp) | DESIGN | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | Protein kinase C theta (PKC theta) | SOTRASTAURIN | THERAPY | DISEASES | AEB071 | GLYCOPROTEIN | ABSORPTION | PKC-THETA | CYCLOSPORINE | Protein Kinase C - genetics | Pyrimidines - chemical synthesis | Humans | Microsomes, Liver - metabolism | Protein Kinase C-theta | Structure-Activity Relationship | Pyrimidines - chemistry | Protein Kinase Inhibitors - chemistry | Drug Interactions | Cytochrome P-450 CYP3A - genetics | T-Lymphocytes - metabolism | Isoenzymes - metabolism | Microsomes, Liver - drug effects | Protein Kinase C - metabolism | T-Lymphocytes - drug effects | T-Lymphocytes - pathology | Protein Kinase Inhibitors - chemical synthesis | Gene Expression | Signal Transduction | Isoenzymes - genetics | Protein Kinase C - antagonists & inhibitors | Pyrimidines - pharmacology | ATP Binding Cassette Transporter, Subfamily B, Member 1 - genetics | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Cytochrome P-450 CYP3A - metabolism | Halogenation | Protein Kinase Inhibitors - pharmacology | Isoenzymes - antagonists & inhibitors | Drug Resistance, Neoplasm - drug effects | Physicians (General practice) | Liability (Law) | Protein kinases | Drug interactions | Complications and side effects | Rheumatoid factor | Cytochrome P-450 | Arthritis | Drug discovery | T cells
Journal Article
FEBS Letters, ISSN 0014-5793, 10/2011, Volume 585, Issue 20, pp. 3208 - 3215
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2008, Volume 51, Issue 19, pp. 5958 - 5963
Journal Article
Fish and Shellfish Immunology, ISSN 1050-4648, 04/2019, Volume 87, pp. 788 - 795
Haemorrhagic disease caused by grass carp reovirus (GCRV) can result in large-scale death of young grass carp, leading to irreparable economic losses that... 
Host immune defences | Grass carp | Grass carp reovirus (GCRV) | Protein kinase C (PKC) | CTENOPHARYNGODON-IDELLUS | DOMAIN | IMMUNOLOGY | FAMILY | FISHERIES | MARINE & FRESHWATER BIOLOGY | VETERINARY SCIENCES | MOLECULAR-CLONING | DRUG TARGET | BINDING | T-CELLS
Journal Article
Science, ISSN 0036-8075, 4/2010, Volume 328, Issue 5976, pp. 372 - 376
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2017, Volume 76, Issue Suppl 2, p. 780
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 04/2015, Volume 94, Issue 4, pp. 241 - 256
Journal Article