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Journal Article
Journal Article
Journal Article
Journal Article
The Journal of Pathology, ISSN 0022-3417, 07/2017, Volume 242, Issue 3, pp. 358 - 370
Focal adhesion kinase ( FAK ) inhibitors have been developed as potential anticancer agents and are undergoing clinical trials. In vitro activation of the FAK... 
tumour angiogenesis | focal adhesion kinase | LOCALIZATION | ACTIVATION | PERMEABILITY | PHOSPHORYLATION | BARRIER FUNCTION | TUMOR ANGIOGENESIS | PATHOLOGY | SRC-FAMILY KINASES | CANCER | ONCOLOGY | SMOOTH-MUSCLE-CELLS | AUTOPHOSPHORYLATION | Cell Division - genetics | Focal Adhesion Kinase 1 - genetics | Neoplasm Transplantation | Antineoplastic Agents, Hormonal - pharmacology | Melanoma - blood supply | Focal Adhesion Protein-Tyrosine Kinases - metabolism | Capillary Permeability - drug effects | Melanoma - enzymology | Endothelium, Vascular - enzymology | Focal Adhesion Protein-Tyrosine Kinases - deficiency | Mutation - genetics | Capillary Permeability - genetics | Focal Adhesion Protein-Tyrosine Kinases - genetics | Homozygote | Neovascularization, Pathologic - enzymology | Animals | Melanoma - genetics | Tamoxifen - pharmacology | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Mice | Cell Hypoxia - genetics | Focal Adhesion Kinase 1 - metabolism | Tyrosine | Fibronectins | Platelet-derived growth factor | Endothelial growth factors | Analysis | Melanoma | Phenols | Genetic aspects | Neovascularization | Permeability | Endothelium | Residues | Phosphorylation | Clinical trials | Activation | Kinases | Blood | Fibronectin | Anticancer properties | Angiogenesis | Antitumor agents | Leakage | Medical research | Vessels | Blood vessels | Tamoxifen | Cadherin | Src protein | Adhesion | Pathology | Signaling | Inhibitors | Hypoxia | In vivo methods and tests | Mutation | Focal adhesion kinase | Paxillin | In vitro methods and tests | Tumors | Original Paper | Original Papers
Journal Article
Oncogene, ISSN 0950-9232, 12/2009, Volume 28, Issue 49, pp. 4326 - 4343
Mammographically dense breast tissue is one of the greatest risk factors for developing breast carcinoma, yet the associated molecular mechanisms remain... 
3D matrix/focal adhesion | Breast cancer | Mechanotransduction | Epithelial morphogenesis | Cell-extracellular matrix interaction | Breast tissue density | CANCER RISK | ACTIVATED PROTEIN-KINASE | mechanotransduction | BIOCHEMISTRY & MOLECULAR BIOLOGY | breast cancer | MALIGNANT PHENOTYPE | CARCINOMA IN-SITU | CELL BIOLOGY | MAMMOGRAPHIC DENSITY | STRESS FIBERS | ONCOLOGY | epithelial morphogenesis | EPITHELIAL-SPECIFIC DISRUPTION | GROWTH-FACTORS | GENETICS & HEREDITY | EXTRACELLULAR-MATRIX | FOCAL ADHESION KINASE | breast tissue density | cell-extracellular matrix interaction | Cell Proliferation | Oligonucleotide Array Sequence Analysis | Cell Count | Humans | Breast Neoplasms - etiology | Gene Expression Profiling | Extracellular Signal-Regulated MAP Kinases - metabolism | Mammary Glands, Human - metabolism | Mechanotransduction, Cellular - physiology | Carcinoma - etiology | Extracellular Matrix - chemistry | Breast Neoplasms - metabolism | Cell Transformation, Neoplastic - genetics | Extracellular Matrix - physiology | Gene Expression - physiology | Female | Mammary Glands, Human - physiology | Extracellular Signal-Regulated MAP Kinases - physiology | Focal Adhesion Kinase 1 - metabolism | Mechanotransduction, Cellular - genetics | Mammary Glands, Human - cytology | Risk Factors | Cells, Cultured | Focal Adhesion Kinase 1 - physiology | Cell Transformation, Neoplastic - metabolism | Phenotype | Breast Neoplasms - genetics | Carcinoma - genetics | Carcinoma - metabolism | Physiological aspects | Development and progression | Genetic aspects | Research | Gene expression | Protein kinases | Risk factors | Genotype & phenotype | Cellular biology | 3D-Matrix | Focal Adhesion | Cell-Extracellular Matrix Interaction | Epithelial Morphogenesis | Breast Cancer | Breast Tissue Density | Tumor-Stroma Interaction
Journal Article
Nature Cell Biology, ISSN 1465-7392, 02/2004, Volume 6, Issue 2, pp. 154 - 161
Journal Article