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Nature Structural & Molecular Biology, ISSN 1545-9993, 12/2004, Volume 11, Issue 12, pp. 1192 - 1197
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2007, Volume 9, Issue 3, pp. 324 - 330
The mitogen-activated protein kinase (MAPK) network is a conserved signalling module that regulates cell fate by transducing a myriad of growth-factor signals.... 
ACTIVATION | PROTEIN | SPECIFICITY | PHOSPHORYLATION | DYNAMICS | RAF-1 | CASCADE | IDENTIFICATION | SIGNAL-REGULATED KINASE | TRANSIENT | CELL BIOLOGY | RNA, Small Interfering - genetics | MAP Kinase Signaling System - physiology | Tetradecanoylphorbol Acetate - pharmacology | Receptor, trkA - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - metabolism | PC12 Cells | MAP Kinase Kinase 1 - genetics | Flow Cytometry | Mitogen-Activated Protein Kinase 1 - genetics | Phosphorylation - drug effects | Cell Differentiation - physiology | Proto-Oncogene Proteins B-raf - metabolism | Mitogen-Activated Protein Kinase 3 - genetics | Proto-Oncogene Proteins c-raf - genetics | Nerve Growth Factor - pharmacology | Rats | MAP Kinase Kinase 1 - metabolism | Protein Kinase C - antagonists & inhibitors | Proto-Oncogene Proteins c-raf - metabolism | Animals | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Cell Differentiation - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Models, Biological | Proto-Oncogene Proteins B-raf - genetics | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Epidermal Growth Factor - pharmacology | Cell Cycle - drug effects | Monte Carlo Method | Mitogen-Activated Protein Kinase 1 - metabolism | Cell proliferation | Evaluation | Pheochromocytoma | Physiological aspects | Cell differentiation | Properties | Protein kinases | Growth factors | Index Medicus
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2009, Volume 284, Issue 19, pp. 13165 - 13173
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 07/2009, Volume 94, Issue 7, pp. 2507 - 2515
Context: Adipose tissue in obesity is thought to be exposed to various stresses, predominantly in intraabdominal depots. We recently reported that p38MAPK and... 
OXIDATIVE STRESS | METABOLIC SYNDROME | OBESITY | IMPACT | DISEASE | ENDOCRINOLOGY & METABOLISM | ENDOPLASMIC-RETICULUM | REGULATING KINASE-1 | FAMILY PROTEINS | SUBCUTANEOUS FAT | ADIPOSE-TISSUE | MAP Kinase Kinase 4 - physiology | Obesity - immunology | Humans | Middle Aged | JNK Mitogen-Activated Protein Kinases - metabolism | MAP Kinase Kinase Kinase 5 - physiology | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Case-Control Studies | Inflammation - metabolism | MAP Kinase Kinase 4 - metabolism | Insulin Resistance - physiology | Adult | Female | p38 Mitogen-Activated Protein Kinases - metabolism | Chemotaxis - immunology | MAP Kinase Kinase Kinase 5 - metabolism | Extracellular Signal-Regulated MAP Kinases - physiology | Macrophages - immunology | Intra-Abdominal Fat - immunology | Macrophages - physiology | Stress, Physiological - physiology | MAP Kinase Kinase Kinase 5 - genetics | p38 Mitogen-Activated Protein Kinases - physiology | Inflammation - immunology | Omentum - metabolism | Intra-Abdominal Fat - metabolism | Obesity - metabolism | Obesity - pathology | Macrophages - metabolism | JNK Mitogen-Activated Protein Kinases - physiology | Omentum - pathology | Signal Transduction - physiology | Aged | Intra-Abdominal Fat - enzymology | Intra-Abdominal Fat - pathology | Enzyme Activation - physiology | Index Medicus | Abridged Index Medicus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 12/2003, Volume 5, Issue 12, pp. 1104 - 1110
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 04/2009, Volume 8, Issue 4, pp. 834 - 843
Journal Article
Science Signaling, ISSN 1945-0877, 03/2011, Volume 4, Issue 166, pp. ra17 - ra17
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2012, Volume 287, Issue 21, pp. 17100 - 17108
Naturally occurring Foxp3(+)CD4(+)CD25(+) T regulatory cell (nTreg)-mediated suppression of lung allergic responses is abrogated following ligation of... 
KAPPA-B ACTIVATION | TGF-BETA | PROTEIN | INDUCED TNF RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION FACTOR FOXP3 | AIRWAY HYPERREACTIVITY | LUNG ALLERGIC RESPONSES | COSTIMULATION | LIGAND | CUTTING EDGE | MAP Kinase Kinase 7 - genetics | T-Lymphocytes, Regulatory - metabolism | Asthma - metabolism | MAP Kinase Signaling System - physiology | Immune Tolerance - physiology | MAP Kinase Kinase 7 - immunology | NF-kappa B - immunology | MAP Kinase Kinase 4 - immunology | NF-kappa B - metabolism | Enzyme Activation - immunology | T-Lymphocytes, Regulatory - immunology | Autoimmune Diseases - genetics | MAP Kinase Kinase 7 - metabolism | Phosphorylation - genetics | MAP Kinase Kinase 4 - metabolism | Asthma - immunology | Female | Lung - metabolism | Phosphorylation - immunology | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | Autoimmune Diseases - metabolism | Immune Tolerance - drug effects | Autoimmune Diseases - immunology | Glucocorticoid-Induced TNFR-Related Protein - metabolism | Glucocorticoid-Induced TNFR-Related Protein - genetics | p38 Mitogen-Activated Protein Kinases - genetics | p38 Mitogen-Activated Protein Kinases - immunology | Enzyme Activation - drug effects | Anthracenes - pharmacology | Asthma - genetics | Mice, Knockout | Animals | MAP Kinase Signaling System - drug effects | NF-kappa B - genetics | MAP Kinase Kinase 4 - genetics | Cell Proliferation - drug effects | Glucocorticoid-Induced TNFR-Related Protein - immunology | Mice | Protein Kinase Inhibitors - pharmacology | Enzyme Activation - genetics | Lung - immunology | Index Medicus | MAP Kinases (MAPKs) | GITR | Signal Transduction | Cell Signaling | CD4+CD25+Foxp3+ T Regulatory Cells | Cellular Immune Response | Asthma | Jun N-terminal Kinase (JNK) | SP600125
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology: Journal of the American Heart Association, ISSN 1079-5642, 05/2003, Volume 23, Issue 5, pp. 795 - 801
OBJECTIVE—We investigated the comparative roles of mitogen-activated protein (MAP) kinases, including c-Jun NH2-terminal kinase (JNK), extracellular... 
Vascular smooth muscle cell | Platelet-derived growth factor | Proliferation | Gene transfer | Gene expression | PATHWAYS | FACTOR-BETA | gene transfer | proliferation | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | platelet-derived growth factor | RAT MODEL | PDGF | DISEASE | PERIPHERAL VASCULAR DISEASE | vascular smooth muscle cell | ACTIVATED PROTEIN-KINASES | C-JUN | HEMATOLOGY | SIGNAL-REGULATED KINASE | gene expression | SMOOTH-MUSCLE CELLS | Mitogen-Activated Protein Kinase Kinases - genetics | Hyperplasia | Cyclins - genetics | Mitogen-Activated Protein Kinase Kinases - physiology | Recombinant Fusion Proteins - physiology | Mitogen-Activated Protein Kinase 1 - deficiency | Male | Transforming Growth Factor beta - biosynthesis | Cyclins - biosynthesis | MAP Kinase Kinase 4 | Mitogen-Activated Protein Kinase 1 - genetics | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | JNK Mitogen-Activated Protein Kinases | Plasminogen Activator Inhibitor 1 - genetics | p38 Mitogen-Activated Protein Kinases | Carotid Artery Injuries - pathology | Muscle, Smooth, Vascular - drug effects | Transforming Growth Factor beta1 | Transduction, Genetic | Mitogen-Activated Protein Kinase 1 - physiology | Cyclin-Dependent Kinase Inhibitor p21 | Proto-Oncogene Proteins c-sis | Rats | Chemokine CCL2 - genetics | Cell Cycle Proteins - biosynthesis | Mitogen-Activated Protein Kinase Kinases - deficiency | Platelet-Derived Growth Factor - pharmacology | Muscle, Smooth, Vascular - cytology | Rats, Sprague-Dawley | Cell Division - drug effects | Cyclin-Dependent Kinase Inhibitor p27 | Gene Expression Regulation - drug effects | Mitogen-Activated Protein Kinases - deficiency | Cell Movement - drug effects | Plasminogen Activator Inhibitor 1 - biosynthesis | Animals | Transforming Growth Factor beta - genetics | Tunica Intima - pathology | Mitogen-Activated Protein Kinases - physiology | Chemokine CCL2 - biosynthesis | Mitogen-Activated Protein Kinases - genetics | Tumor Suppressor Proteins - biosynthesis | Muscle, Smooth, Vascular - enzymology | Mitogen-Activated Protein Kinase 3 | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, pp. e66796 - e66796
Human protein kinases (HPKs) have profound effects on cellular responses. To better understand the role of HPKs and the signaling networks that influence... 
A VIRUS | SIGNAL-TRANSDUCTION | ANTIVIRAL THERAPY | AVIAN INFLUENZA | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | IN-VIVO | CELL-CYCLE ARREST | NF-KAPPA-B | RESISTANT INFLUENZA | RESPIRATORY SYNCYTIAL VIRUS |