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Journal of Ethnopharmacology, ISSN 0378-8741, 07/2012, Volume 142, Issue 2, pp. 488 - 495
Several Asian plants are known for their anti-diabetic properties and produce alkaloids and flavonoids that may stimulate insulin secretion. Using Vietnamese... 
Alkaloids | Flavonoids | Insulin release | Pancreatic islets | Nuciferine | NELUMBO-NUCIFERA | CHEMISTRY, MEDICINAL | RAT ISLETS | RELEASE | PLANT SCIENCES | DIABETES-MELLITUS | INTEGRATIVE & COMPLEMENTARY MEDICINE | GLUCOSE | ETHANOL | PHARMACOLOGY & PHARMACY | INS-1 CELLS | MICE | K+ CHANNELS | Plant Extracts - chemistry | Antihypertensive Agents - pharmacology | Diazoxide - pharmacology | Cyclic AMP-Dependent Protein Kinases - pharmacology | Plant Extracts - pharmacology | Aporphines - isolation & purification | Nimodipine - pharmacology | Sulfonylurea Receptors | Insulin-Secreting Cells - metabolism | Vietnam | Glyburide - pharmacology | ATP-Binding Cassette Transporters - metabolism | Insulin Secretion | Cell Line | Nelumbo - chemistry | Glucose - pharmacology | Potassium - pharmacology | Aporphines - adverse effects | Receptors, Drug - metabolism | Aporphines - pharmacology | Hypoglycemic Agents - pharmacology | KATP Channels - metabolism | Insulin - metabolism | Animals | Insulin-Secreting Cells - drug effects | Mice | Protein Kinase C - pharmacology | Potassium Channels, Inwardly Rectifying - metabolism | Plant Extracts - adverse effects | Pancreatic beta cells | Albumin | Diazoxide | Insulin | Nimodipine | Ionization | Analysis | Dimethyl sulfoxide | Carbonates | Glibenclamide | Protein kinases | Mass spectrometry | Enzyme-linked immunosorbent assay | Isoflavones | Index Medicus
Journal Article
Journal Article
Kidney International, ISSN 0085-2538, 07/2017, Volume 92, Issue 1, pp. 101 - 113
Macrophage activation is increased in diabetes and correlated with the onset and progression of vascular complications. To identify drugs that could inhibit... 
macrophages | fibrosis | inflammation | diabetes | PROTEIN | PERIPHERAL-BLOOD | NEPHROPATHY | MONOCYTIC CELLS | BETA | ALPHA-TOCOPHEROL SUPPLEMENTATION | CYTOKINE PRODUCTION | INSULIN-RESISTANCE | UROLOGY & NEPHROLOGY | PLASMA-GLUCOSE | Tumor Necrosis Factor-alpha - metabolism | Diabetes Mellitus, Experimental - drug therapy | Phosphorylation | Diabetic Cardiomyopathies - metabolism | Kidney - pathology | Streptozocin | Humans | Diabetes Mellitus, Experimental - genetics | Male | NF-kappa B - metabolism | beta-Arrestin 2 - metabolism | Receptors, Adrenergic, beta-2 - drug effects | Adrenergic beta-2 Receptor Agonists - pharmacology | Kidney - metabolism | Transfection | RNA Interference | Time Factors | Protein Kinase C - metabolism | Myocardium - metabolism | Diabetic Cardiomyopathies - prevention & control | Diabetes Mellitus, Experimental - chemically induced | Diabetes Mellitus, Experimental - metabolism | Diabetic Nephropathies - prevention & control | Adrenergic beta-2 Receptor Antagonists - pharmacology | Kidney - drug effects | Anti-Inflammatory Agents - pharmacology | Receptors, Adrenergic, beta-2 - genetics | Diabetic Nephropathies - metabolism | Diabetic Nephropathies - chemically induced | THP-1 Cells | beta-Arrestin 2 - genetics | Diabetic Nephropathies - genetics | Myocardium - pathology | Rats, Sprague-Dawley | Receptors, Adrenergic, beta-2 - metabolism | Diabetic Cardiomyopathies - genetics | Rats, Zucker | Macrophages - metabolism | Animals | NF-KappaB Inhibitor alpha - metabolism | Fibrosis | Macrophages - drug effects | Diabetic Cardiomyopathies - chemically induced | Macrophage Activation - drug effects
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2008, Volume 28, Issue 52, pp. 14062 - 14073
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e36949
Many molecular and cellular abnormalities detected in the diabetic retina support a role for IL-1 beta-driven neuroinflammation in the pathogenesis of diabetic... 
ADHESION MOLECULE-1 | PROTEIN-KINASE-C | MICROGLIAL ACTIVATION | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | GENE-EXPRESSION | RETINOPATHY | INDUCTION | INTERLEUKIN-1 INDUCES INTERLEUKIN-1 | MULLER CELLS | BRAIN | Microglia - metabolism | Up-Regulation | Retina - metabolism | Rats, Wistar | Diabetes Mellitus, Experimental - genetics | Male | Interleukin-1beta - genetics | Glial Fibrillary Acidic Protein - metabolism | Hyperglycemia - genetics | Glucose - administration & dosage | Interleukin-1beta - metabolism | Protein Kinase C - metabolism | Diabetes Mellitus, Experimental - metabolism | Interleukin-1beta - antagonists & inhibitors | Retinal Vessels - metabolism | Endothelial Cells - metabolism | Rats | Protein Kinase C - antagonists & inhibitors | Random Allocation | Rats, Sprague-Dawley | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - genetics | Hyperglycemia - metabolism | alpha-Macroglobulins - metabolism | Animals | Endothelium - metabolism | Ceruloplasmin - metabolism | Glucose - metabolism | Neuroglia - metabolism | Astrocytes - metabolism | Ceruloplasmin | Diabetic retinopathy | Protein kinase C | Retinopathy | Pathogenesis | Streptozocin | Retina | Immunoblotting | Glucose | Hyperglycemia | Ischemia | Rodents | Enzyme-linked immunosorbent assay | Enzymes | Cytokines | Astrocytes | Abnormalities | Diabetes mellitus | Blood vessels | Inflammation | IL-1β | Endothelial cells | Endothelium | Microglia | Polymerase chain reaction | Brain research | Diabetes | Glia | Laboratory animals | Subcultures | Apoptosis
Journal Article
Journal Article