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Journal of Cell Biology, ISSN 0021-9525, 04/2013, Volume 201, Issue 2, pp. 217 - 231
Journal Article
Nature Cell Biology, ISSN 1465-7392, 04/2013, Volume 15, Issue 4, pp. 430 - 439
Polo-like kinase 1 (PLK1) critically regulates mitosis through its dynamic localization to kinetochores, centrosomes and the midzone. The polo-box domain (PBD)... 
E3 LIGASE | CELL-DIVISION | COMPLEX | POLO-BOX DOMAIN | KINASE-1 | POLO-LIKE-KINASE-1 | ROLES | RING UBIQUITIN LIGASES | SPINDLE-ASSEMBLY CHECKPOINT | AURORA-B | CELL BIOLOGY | RNA, Small Interfering - genetics | Phosphorylation | Immunoprecipitation | Humans | Ubiquitin - metabolism | Molecular Sequence Data | Cell Cycle Proteins - antagonists & inhibitors | Microtubules - metabolism | Ubiquitination | Spindle Apparatus - metabolism | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | Cullin Proteins - metabolism | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Amino Acid Sequence | Proto-Oncogene Proteins - antagonists & inhibitors | Cullin Proteins - antagonists & inhibitors | Kinetochores - metabolism | Signal Transduction | Chromosomes, Human - genetics | RNA, Messenger - genetics | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins - genetics | Blotting, Western | Centrosome - metabolism | Cullin Proteins - genetics | Sequence Homology, Amino Acid | Mitosis - physiology | Adaptor Proteins, Signal Transducing - genetics | Protein Array Analysis | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | Microscopy, Fluorescence | Physiological aspects | Research | Ubiquitin-proteasome system | Mitosis | Protein kinases | Life Sciences
Journal Article
JOURNAL OF CELL BIOLOGY, ISSN 0021-9525, 04/2019, Volume 218, Issue 4, pp. 1182 - 1199
Spindle checkpoint signaling is initiated by recruitment of the kinase MPS1 to unattached kinetochores during mitosis. We show that CDK1-CCNB1 and a... 
CELL-DIVISION | ANAPHASE | ASSEMBLY CHECKPOINT | DEPENDENT PHOSPHORYLATION | COMPLEX | ACTIVATION | MICROTUBULE-BINDING | CDK1 | GREATWALL KINASE | AURORA-B | CELL BIOLOGY | Proteins | Signaling | Phosphorylation | Mitosis | Kinetochores | Metaphase | Tethering | Dephosphorylation | Kinases | Localization | Anaphase | Recruitment
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 11/2009, Volume 187, Issue 5, pp. 637 - 653
Dynamic localization of the chromosomal passenger complex (CPC) during mitosis is essential for its diverse functions. CPC targeting to centromeres involves... 
Passengers | Auroras | Mitosis | Kinetochores | Microtubules | Cell lines | Centromeres | Cytokinesis | Anaphase | Chromosomes | GENETIC-ANALYSIS | ANAPHASE TRANSITION | PHOSPHORYLATION | VERTEBRATE CELLS | INNER CENTROMERE | CENP-H | CLEAVAGE FURROW | CENTROMERE PROTEIN INCENP | OUTER KINETOCHORE | SPINDLE-ASSEMBLY CHECKPOINT | CELL BIOLOGY | Observations | Properties | Phosphotransferases
Journal Article
Cell Reports, ISSN 2211-1247, 05/2016, Volume 15, Issue 8, pp. 1624 - 1633
Journal Article
PLOS GENETICS, ISSN 1553-7404, 06/2019, Volume 15, Issue 6, p. e1008061
The nuclear pore complex (NPC) forms a gateway for nucleocytoplasmic transport. The outer ring protein complex of the NPC (the Nup107-160 subcomplex in humans)... 
3-DIMENSIONAL STRUCTURE | KINETOCHORES | PROTEIN | MOLECULAR ARCHITECTURE | STRUCTURAL-ANALYSIS | GENETICS & HEREDITY | NUP98 | IDENTIFICATION | EXPRESSION | SCHIZOSACCHAROMYCES-POMBE | NUCLEOPORINS | Proteins | Physiological aspects | Genetic aspects | Yeast fungi | Yeast | Funding | Meiosis | Kinases | Clonal deletion | Microscopy | Cell cycle | Life sciences | Communications technology | Protein transport | Localization | Chromosomes | Methods
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2007, Volume 104, Issue 25, pp. 10571 - 10576
A universal mark of centromeric chromatin is its packaging by a variant of histone H3 known as centromeric H3 (CenH3). The mechanism by which CenH3s are... 
Proteins | Fungi | Yeasts | rev genes | Plasmids | DNA | Kinetochores | Centromeres | Histones | Genetic mutation | Centromeric H3 | Kinetochore | Yeast | CENP-A | Chromosome segregation | Temperature | Mitosis | Saccharomyces cerevisiae - genetics | Molecular Sequence Data | Phylogeny | Threonine - metabolism | Genetic Complementation Test | Centromere - chemistry | DNA-Binding Proteins - metabolism | Chromatin Immunoprecipitation | G2 Phase | Chromosomal Proteins, Non-Histone - physiology | Protein Structure, Tertiary | Amino Acid Sequence | Saccharomyces cerevisiae - physiology | Chromosomal Proteins, Non-Histone - metabolism | Saccharomyces cerevisiae Proteins - genetics | DNA-Binding Proteins - genetics | Amino Acid Motifs | Chromosomal Proteins, Non-Histone - genetics | Leucine - chemistry | Sequence Homology, Amino Acid | Two-Hybrid System Techniques | Nuclear Export Signals | Centromere - genetics | Hemagglutinins - chemistry | Alleles | Bayes Theorem | Saccharomyces cerevisiae Proteins - metabolism | Models, Genetic | Saccharomyces cerevisiae Proteins - physiology | Chromosomal Proteins, Non-Histone - chemistry | Saccharomyces cerevisiae - growth & development | Amino Acid Substitution | Saccharomyces cerevisiae Proteins - chemistry | kinetochore | Biological Sciences | chromosome segregation | centromeric H3 | yeast
Journal Article