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Journal Article
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 2014, Volume 13, Issue 5, pp. 1217 - 1230
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 08/2015, Volume 34, Issue 35, pp. 4581 - 4590
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 11/2014, Volume 33, Issue 46, pp. 5360 - 5369
PI3-kinase has a crucial role in transformation mediated by the oncogenic c-Kit mutant D816V. In this study, we demonstrate that the c-Kit/D816V-mediated cell... 
GENE-MUTATIONS | ACTIVATION | c-Kit | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PI3-kinase | ACUTE MYELOID-LEUKEMIA | DASATINIB | PHOSPHOINOSITIDE 3-KINASE | SYSTEMIC MASTOCYTOSIS | CELL BIOLOGY | cell transformation | BREAST-CANCER | p110 delta | ONCOLOGY | AGGRESSIVE MASTOCYTOSIS | GROWTH | GENETICS & HEREDITY | c-Kit/D816V | phosphorylation | Class Ia Phosphatidylinositol 3-Kinase - metabolism | Cell Proliferation | Cell Survival - genetics | Cercopithecus aethiops | Mutation, Missense | Proto-Oncogene Proteins c-kit - metabolism | RNA Interference | Cell Transformation, Neoplastic - genetics | Female | Proto-Oncogene Proteins c-kit - genetics | Phosphorylation - drug effects | Chromones - pharmacology | Class Ia Phosphatidylinositol 3-Kinase - genetics | Cell Line | Adenine - analogs & derivatives | Morpholines - pharmacology | Serine - genetics | Adenine - pharmacology | Binding Sites - genetics | Mice, Inbred Strains | Cell Transformation, Neoplastic - metabolism | Serine - metabolism | Blotting, Western | Class Ia Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Tyrosine - metabolism | Animals | Mice, Nude | Cell Line, Tumor | Protein Binding | Cell Transformation, Neoplastic - drug effects | Quinazolines - pharmacology | COS Cells | Tyrosine - genetics | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Cancer and Oncology | Klinisk medicin | Cancer och onkologi
Journal Article