X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (9037) 9037
Publication (819) 819
Book Review (23) 23
Book Chapter (12) 12
Dissertation (7) 7
Conference Proceeding (6) 6
Book / eBook (3) 3
Data Set (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (8400) 8400
rats (5620) 5620
kainic acid - pharmacology (4715) 4715
male (4362) 4362
neurosciences (4044) 4044
kainic acid (3405) 3405
rats, sprague-dawley (1836) 1836
neurons - drug effects (1681) 1681
mice (1670) 1670
index medicus (1566) 1566
hippocampus - drug effects (1503) 1503
hippocampus (1307) 1307
glutamate (1297) 1297
excitatory amino acid agonists - pharmacology (1284) 1284
rats, wistar (1265) 1265
pharmacology & pharmacy (1247) 1247
neurons (1196) 1196
cells, cultured (1131) 1131
brain (1126) 1126
female (1122) 1122
epilepsy (1000) 1000
hippocampus - metabolism (996) 996
in vitro techniques (996) 996
dose-response relationship, drug (976) 976
kainic acid - toxicity (945) 945
neurons - metabolism (905) 905
humans (899) 899
seizures (899) 899
rats, inbred strains (896) 896
excitatory amino acid antagonists - pharmacology (891) 891
seizures - chemically induced (874) 874
kainate (870) 870
n-methylaspartate - pharmacology (815) 815
disease models, animal (784) 784
biochemistry & molecular biology (771) 771
rat (765) 765
neurons - physiology (755) 755
time factors (683) 683
temporal-lobe epilepsy (632) 632
brain - drug effects (600) 600
rat-brain (598) 598
clinical neurology (594) 594
receptors, kainic acid - metabolism (592) 592
calcium - metabolism (591) 591
brain - metabolism (589) 589
excitotoxicity (561) 561
hippocampus - cytology (556) 556
glutamic acid (552) 552
expression (545) 545
hippocampus - pathology (545) 545
immunohistochemistry (542) 542
glutamates - pharmacology (535) 535
kainic acid - analogs & derivatives (524) 524
glutamate receptors (507) 507
membrane potentials - drug effects (501) 501
electrophysiology (470) 470
patch-clamp techniques (466) 466
quinoxalines - pharmacology (466) 466
receptors (456) 456
neurology (454) 454
neuroprotective agents - pharmacology (453) 453
status epilepticus (449) 449
receptors, ampa - metabolism (447) 447
hippocampus - physiology (446) 446
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid - pharmacology (445) 445
methyl-d-aspartate (433) 433
glutamic acid - pharmacology (432) 432
behavior, animal - drug effects (430) 430
physiology (427) 427
glutamic acid - metabolism (426) 426
kinetics (422) 422
electric stimulation (411) 411
nervous system (409) 409
mice, inbred c57bl (406) 406
rat hippocampus (404) 404
animals, newborn (403) 403
neurotoxicity (403) 403
receptors, kainic acid - antagonists & inhibitors (403) 403
activation (400) 400
article (398) 398
aspartic acid - pharmacology (396) 396
seizures - physiopathology (393) 393
pyrrolidines - pharmacology (390) 390
hippocampal-neurons (387) 387
receptors, ampa - antagonists & inhibitors (383) 383
receptors, kainic acid - physiology (383) 383
analysis (374) 374
nmda (374) 374
corpus striatum - drug effects (373) 373
anticonvulsants - pharmacology (372) 372
synaptic transmission - drug effects (367) 367
cell death - drug effects (366) 366
neurons - pathology (364) 364
neurons - cytology (363) 363
ampa (361) 361
neuroprotection (350) 350
cerebral cortex - drug effects (345) 345
kainic acid - administration & dosage (341) 341
seizure (340) 340
central-nervous-system (337) 337
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (8896) 8896
Russian (50) 50
Chinese (40) 40
Japanese (30) 30
French (13) 13
Italian (4) 4
Spanish (4) 4
Ukrainian (4) 4
German (3) 3
Czech (2) 2
Polish (2) 2
Afrikaans (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Neuroscience, ISSN 0270-6474, 03/2006, Volume 26, Issue 11, pp. 2852 - 2861
Glutamate receptor (GluR) ion channels mediate fast synaptic transmission in the mammalian CNS. Numerous crystallographic studies, the majority on the... 
Glutamate receptor | Kainate | Antagonist | Structure | Crystallography | Gating | ACTIVATION | NMDA RECEPTORS | MECHANISM | MODEL | kainate | antagonist | NEUROSCIENCES | structure | GLUTAMATE-RECEPTOR | crystallography | AMPA RECEPTORS | glutamate receptor | gating | DYNAMICS | PARTIAL AGONIST ACTION | ION CHANNELS | SUBUNIT | Excitatory Amino Acid Antagonists - metabolism | Receptors, Kainic Acid - chemistry | Protein Conformation - drug effects | Thymine - analogs & derivatives | Receptors, AMPA - chemistry | Alanine - chemistry | Crystallography, X-Ray | Receptors, Kainic Acid - antagonists & inhibitors | Oocytes | Quinoxalines - pharmacology | Alanine - analogs & derivatives | Recombinant Fusion Proteins - antagonists & inhibitors | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Excitatory Amino Acid Antagonists - chemistry | Thymine - pharmacology | Binding Sites | Alanine - pharmacology | Thymine - metabolism | Thymine - chemistry | Glutamic Acid - pharmacology | Xenopus laevis | Models, Molecular | Rats | Alanine - metabolism | Excitatory Amino Acid Antagonists - pharmacology | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - metabolism | Recombinant Fusion Proteins - chemistry | Patch-Clamp Techniques | Animals | Hydrogen Bonding | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - chemistry | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology | Protein Binding | Glutamic Acid - metabolism | Glutamic Acid - chemistry | Receptors, AMPA - antagonists & inhibitors | BIOLOGY | GENES | CRYSTAL STRUCTURE | MATERIALS SCIENCE | CHAINS | DIMERS | CONFORMATIONAL CHANGES
Journal Article
Nature Neuroscience, ISSN 1097-6256, 07/2004, Volume 7, Issue 7, pp. 711 - 718
Voltage-dependent Kv2.1 K+ channels, which mediate delayed rectifier Kv currents (I-K), are expressed in large clusters on the somata and dendrites of... 
ALPHA-SUBUNITS | RAT HIPPOCAMPAL-NEURONS | MAMMALIAN BRAIN | ACTIVATION | GATED POTASSIUM CHANNELS | RECEPTOR | NEOCORTICAL PYRAMIDAL NEURONS | IDENTIFICATION | KV2.1 K+ CHANNEL | BINDING | NEUROSCIENCES | Potassium - metabolism | Okadaic Acid - pharmacology | Potassium Channels, Voltage-Gated | Pyramidal Cells - metabolism | Cyclosporine - pharmacology | Cell Count | Neuronal Plasticity - drug effects | Pyrethrins - pharmacology | Translocation, Genetic - drug effects | Patch-Clamp Techniques - methods | Seizures - chemically induced | Dose-Response Relationship, Drug | Potassium Channels - metabolism | Phosphoprotein Phosphatases - pharmacology | Seizures - physiopathology | Drug Interactions | Neuronal Plasticity - physiology | Time Factors | Dendrites - physiology | Potassium Chloride - pharmacology | Nitriles | Pyramidal Cells - drug effects | Phosphorylation - drug effects | Cadmium Chloride - pharmacology | Ionophores - pharmacology | Potassium Channel Blockers - pharmacology | Disease Models, Animal | Animals, Newborn | Membrane Potentials - drug effects | Dendrites - drug effects | Translocation, Genetic - physiology | Glutamic Acid - pharmacology | Kainic Acid - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Excitatory Amino Acid Antagonists - pharmacology | Nitrendipine - pharmacology | Calcium Channel Blockers - pharmacology | Delayed Rectifier Potassium Channels | Hippocampus - cytology | Membrane Potentials - physiology | Shab Potassium Channels | Calcimycin - pharmacology | Blotting, Western | Animals | Ion Channel Gating - drug effects | Physiological aspects | Phosphorylation | Ion channels | Research | Neurons
Journal Article
Neuron, ISSN 0896-6273, 07/2011, Volume 71, Issue 2, pp. 319 - 331
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2008, Volume 578, Issue 2, pp. 171 - 176
Journal Article
Learning and Memory, ISSN 1072-0502, 12/2012, Volume 19, Issue 12, pp. 615 - 626
Na+- dependent high-affinity glutamate transporters have important roles in the maintenance of basal levels of glutamate and clearance of glutamate during... 
QUANTAL ANALYSIS | SYNAPSES | SYNAPTIC-TRANSMISSION | LONG-TERM POTENTIATION | RAT-BRAIN | NEUROLOGIC DISEASE | HIGH-AFFINITY GLUTAMATE | HIPPOCAMPAL-NEURONS | EXPRESSION | NEUROSCIENCES | PLASTICITY | Neurology | Biochemistry | Inhibition | Glycine - analogs & derivatives | Electric Stimulation | Kainic Acid - analogs & derivatives | Male | Protein Transport - drug effects | Glial Fibrillary Acidic Protein - metabolism | Excitatory Postsynaptic Potentials - drug effects | Quinoxalines - pharmacology | Flow Cytometry | Long-Term Potentiation - drug effects | Neurons - physiology | Long-Term Potentiation - physiology | Indoles - pharmacology | Tetrodotoxin - pharmacology | Neurons - drug effects | Animals, Newborn | Astrocytes - drug effects | Biotinylation | Colforsin - pharmacology | Kainic Acid - pharmacology | Valine - analogs & derivatives | Cells, Cultured | Rats | Sodium Channel Blockers - pharmacology | Alanine Transaminase - pharmacology | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Excitatory Amino Acid Transporter 1 - metabolism | Biophysics | Excitatory Amino Acid Transporter 2 - metabolism | Hippocampus - cytology | Rats, Sprague-Dawley | Astrocytes - physiology | Animals | Analysis of Variance | Glycine - pharmacology | Glutamates - pharmacology | Glutamic Acid - metabolism | Valine - pharmacology | In Vitro Techniques | Aspartic Acid - pharmacology
Journal Article
FASEB Journal, ISSN 0892-6638, 04/2012, Volume 26, Issue 4, pp. 1616 - 1628
Prolonged seizures [status epilepticus (SE)] constitute a neurological emergency that can permanently damage the brain. SE results from a failure of the normal... 
Pharmacoresistance | Temporal lobe epilepsy | Anticonvulsant | ATP | EXTRACELLULAR ATP | temporal lobe epilepsy | MICROGLIAL ACTIVATION | TEMPORAL-LOBE EPILEPSY | GLUTAMATE RELEASE | anticonvulsant | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEFICIENT MICE | CELL BIOLOGY | pharmacoresistance | P2X RECEPTOR | BIOLOGY | CENTRAL-NERVOUS-SYSTEM | RAT HIPPOCAMPUS | SYNAPTIC TERMINALS | C-FOS EXPRESSION | Lorazepam - pharmacology | Neuroprotective Agents - therapeutic use | Microglia - metabolism | Seizures - prevention & control | Seizures - drug therapy | Status Epilepticus - chemically induced | Status Epilepticus - drug therapy | Male | Neurons - cytology | Purinergic P2X Receptor Antagonists - pharmacology | Anticonvulsants - pharmacology | Receptors, Purinergic P2X7 - genetics | Seizures - chemically induced | Lorazepam - therapeutic use | Seizures - physiopathology | Neuroprotective Agents - pharmacology | Seizures - pathology | Interleukin-1beta - metabolism | Adenosine Triphosphate - metabolism | Neurons - metabolism | Neurons - drug effects | Microglia - cytology | Glutamic Acid - pharmacology | Kainic Acid - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Status Epilepticus - pathology | Anticonvulsants - therapeutic use | Excitatory Amino Acid Agonists - pharmacology | Hippocampus - pathology | Hippocampus - cytology | Purinergic P2X Receptor Agonists - pharmacology | Mice, Knockout | Animals | Receptors, Purinergic P2X7 - metabolism | Status Epilepticus - physiopathology | Mice
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2015, Volume 125, Issue 10, pp. 3904 - 3914
Valproic acid (VPA) has been widely used for decades to treat epilepsy; however, its mechanism of action remains poorly understood. Here, we report that the... 
MEDICINE, RESEARCH & EXPERIMENTAL | IN-VIVO MICRODIALYSIS | RAT HIPPOCAMPUS | KAINIC ACID | BIPOLAR DISORDER | PALMITOYLATED PROTEINS | SYNAPTIC PLASTICITY | POTASSIUM CHANNEL SUBUNITS | K+ CHANNELS | AKAP SIGNALING COMPLEXES | INDUCED SEIZURES | Muscarinic Agonists - pharmacology | Humans | Seizures - drug therapy | Male | KCNQ2 Potassium Channel - drug effects | Receptor, Muscarinic M1 - physiology | Anticonvulsants - pharmacology | Recombinant Fusion Proteins - metabolism | Valproic Acid - pharmacology | Recombinant Fusion Proteins - drug effects | Seizures - chemically induced | A Kinase Anchor Proteins - genetics | A Kinase Anchor Proteins - physiology | Seizures - physiopathology | Drug Interactions | Protein Processing, Post-Translational - drug effects | Receptor, Muscarinic M1 - drug effects | Muscarinic Antagonists - pharmacology | Female | Valproic Acid - therapeutic use | KCNQ2 Potassium Channel - physiology | Neurons - metabolism | Phosphorylation - drug effects | Kainic Acid - toxicity | Neurons - drug effects | A Kinase Anchor Proteins - metabolism | Action Potentials - drug effects | Potassium Channel Blockers - pharmacology | Carbamates - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Lipoylation - drug effects | Anticonvulsants - therapeutic use | Rats | Hippocampus - cytology | Superior Cervical Ganglion - cytology | Anthracenes - pharmacology | Animals | Signal Transduction - drug effects | Recombinant Fusion Proteins - genetics | Phenylenediamines - pharmacology | Mice | Divalproex | Pharmacology, Experimental | Drug interactions | Dosage and administration | Potassium channels | Research | Valproic acid | Health aspects | Studies | Phosphorylation | Preservation | Epilepsy | Bipolar disorder | Kinases | Potassium | Experiments
Journal Article
Science, ISSN 0036-8075, 10/2003, Volume 302, Issue 5642, pp. 84 - 88
Abnormally high spiking activity can damage neurons. Signaling systems to protect neurons from the consequences of abnormal discharge activity have been... 
Brain | Receptors | Neuroscience | Messenger RNA | Neurons | Forebrain | Research Articles | Endocannabinoids | Genotypes | Hippocampus | Seizures | NERVOUS-SYSTEM | ENDOCANNABINOIDS | GLUTAMATE | MULTIDISCIPLINARY SCIENCES | ANANDAMIDE | SEIZURE | ACUTE NEURONAL INJURY | MICE | RAT-BRAIN | NEUROPROTECTION | N-ACYLETHANOLAMINE PHOSPHOLIPIDS | Brain-Derived Neurotrophic Factor - genetics | Receptors, Drug - genetics | gamma-Aminobutyric Acid - metabolism | Furans - pharmacology | Epilepsy - metabolism | Male | Epilepsy - physiopathology | Hippocampus - drug effects | Neuroprotective Agents - metabolism | Prosencephalon - drug effects | Brain - metabolism | Polyunsaturated Alkamides | Arachidonic Acids - metabolism | Piperidines - pharmacology | Excitatory Postsynaptic Potentials | Neurons - physiology | Brain-Derived Neurotrophic Factor - metabolism | Neurons - metabolism | Prosencephalon - metabolism | Neurons - drug effects | Cannabinoids - metabolism | Pyrazoles - pharmacology | Signal Transduction | Kainic Acid - pharmacology | Mice, Inbred C57BL | Mice, Transgenic | Excitatory Amino Acid Agonists - pharmacology | Glycerides - metabolism | Arachidonic Acids - pharmacology | Receptors, Drug - metabolism | Mice, Knockout | Brain - drug effects | Gene Expression Regulation - drug effects | Hippocampus - metabolism | Animals | Receptors, Cannabinoid | Glutamic Acid - metabolism | Mice | Genes, Immediate-Early | Mutation | In Vitro Techniques | Receptors, Drug - antagonists & inhibitors | Mitogen-Activated Protein Kinases - metabolism | Physiological aspects | Nervous system | Cannabinoids | Research | Convulsions & seizures
Journal Article