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Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2011, Volume 54, Issue 16, pp. 5868 - 5877
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 08/2018, Volume 43, Issue 9, pp. 1803 - 1804
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 09/2013, Volume 4, Issue 9, pp. 1256 - 1266
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, pp. e70701 - e70701
Background: Nor-BNI, GNTI and JDTic induce selective kappa opioid antagonism that is delayed and extremely prolonged, but some other effects are of rapid onset... 
SITE | IN-VITRO | LIGANDS | BINALTORPHIMINE | MULTIDISCIPLINARY SCIENCES | SPINAL-CORD | MICE | ALLOSTERIC MODULATION | AGONISTS | NOCICEPTIN/ORPHANIN FQ RECEPTOR | P-GLYCOPROTEIN | Naltrexone - analogs & derivatives | Receptors, Opioid, delta - metabolism | Calcium - metabolism | Allosteric Regulation | Humans | Guanidines - pharmacology | Naltrexone - pharmacology | Morphinans - metabolism | Narcotic Antagonists - metabolism | Biological Transport | Piperidines - pharmacology | Guanidines - metabolism | Morphinans - pharmacology | Naltrexone - metabolism | Caco-2 Cells | Receptors, Adrenergic, alpha - metabolism | Tetrahydroisoquinolines - pharmacology | Receptors, Opioid, kappa - antagonists & inhibitors | Piperidines - metabolism | Receptors, Opioid, mu - metabolism | Receptors, Opioid, kappa - metabolism | Norepinephrine - metabolism | Tetrahydroisoquinolines - metabolism | Narcotic Antagonists - pharmacology | Protein Binding | Kinetics | Norepinephrine Plasma Membrane Transport Proteins - metabolism | Competition | Calcium | Central nervous system | Mental health | Radioisotopes | Antagonists | Selectivity | Medical schools | Proteins | Psychotropic drugs | Receptors | Allosteric properties | Rodents | Noradrenaline | Drug dosages | Efflux | Calcium mobilization | Narcotics | Opioid receptors | Hospitals | Affinity | Adrenergic receptors | Norepinephrine | Psychiatry | Transporter | Receptors (physiology) | Index Medicus
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2011, Volume 657, Issue 1, pp. 89 - 96
The long-lasting post-surgical changes in nociceptive thresholds in mice, indicative of latent pain sensitization, were studied. The contribution of kappa... 
Opioid | Postoperative pain | Remifentanil | Dynorphin | Kappa opioid receptor | Latent pain sensitization | MORPHINE | RATS | SPINAL DYNORPHIN | RECEPTOR ANTAGONIST | KETAMINE | NEUROPATHIC PAIN | LONG-LASTING HYPERALGESIA | PHARMACOLOGY & PHARMACY | INCISIONAL PAIN | FENTANYL | ANTINOCICEPTIVE TOLERANCE | Hyperalgesia - chemically induced | Naltrexone - analogs & derivatives | Pain Threshold - physiology | Narcotic Antagonists - administration & dosage | Spinal Cord - drug effects | Spinal Cord - metabolism | Postoperative Complications - metabolism | Receptors, N-Methyl-D-Aspartate - metabolism | Male | Pain - chemically induced | Pain - metabolism | Naltrexone - pharmacology | Piperidines - pharmacology | Reaction Time - drug effects | Dizocilpine Maleate - administration & dosage | Pain Threshold - drug effects | Dynorphins - metabolism | Postoperative Complications - chemically induced | Piperidines - administration & dosage | Postoperative Complications - physiopathology | Hyperalgesia - metabolism | Receptors, Opioid, kappa - metabolism | Reaction Time - physiology | Hyperalgesia - physiopathology | Animals | Naloxone - pharmacology | Pain - physiopathology | Narcotic Antagonists - pharmacology | Dynorphins - pharmacology | Mice | Dizocilpine Maleate - pharmacology | Methyl aspartate | Aspartate | Index Medicus
Journal Article