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Cell Cycle, ISSN 1538-4101, 03/2013, Volume 12, Issue 5, pp. 783 - 802
.... To test this theory we have analyzed neoplastic clones, presumably immortalized by transfection with overexpressed telomerase or with SV40 tumor virus, for the predicted clonal yet flexible karyotypes... 
aneuploidy proximate carcinogen | clonal and flexible cancer karyotypes | Muller's ratchet | selection for cancer-specific autonomy | karyotypes of immortal clones of telomerase-deficient mice | sub-speciation via karyotypic drift | low probability of speciation | karyotypic linkage of immortality and tumorigenicity | long preneoplastic latency | growth advantages of aneuploidy | Karyotypic linkage of immortality and tumorigenicity | Low probability of speciation | Growth advantages of aneuploidy | Selection for cancer-specific autonomy | Sub-speciation via karyotypic drift | Aneuploidy proximate carcinogen | Karyotypes of immortal clones of telomerase-deficient mice | Clonal and flexible cancer karyotypes | Long preneoplastic latency | LIFE-SPAN | LARGE T-ANTIGEN | NEOPLASTIC TRANSFORMATION | CELL BIOLOGY | IN-VITRO | HUMAN FIBROBLASTS | CHROMOSOME REASSORTMENTS | MULTIDRUG-RESISTANCE | HUMAN TUMOR-CELLS | MAMMARY EPITHELIAL-CELLS | TELOMERE LENGTH | Humans | Aneuploidy | Drug Resistance, Neoplasm | Chromosomes, Human - metabolism | Telomerase - deficiency | Tetraploidy | Diploidy | Phenotype | Animals | Transfection | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Karyotyping | Aged, 80 and over | Cell Line, Tumor | Female | Telomerase - metabolism | Clone Cells | Mice | Cell Transformation, Neoplastic - pathology | Neoplasms - pathology | Simian virus 40 - metabolism | Cell Line, Transformed | Report | Muller’s ratchet
Journal Article
Cell cycle (Georgetown, Tex.), ISSN 1551-4005, 2014, Volume 12, Issue 5, pp. 783 - 802
Journal Article
International journal of molecular sciences, ISSN 1422-0067, 2018, Volume 19, Issue 7, p. 2078
Journal Article
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