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Nature Cell Biology, ISSN 1465-7392, 03/2010, Volume 12, Issue 3, pp. 299 - 305
For most types of cancers, the cell at the origin of tumour initiation is still unknown. Here, we used mouse genetics to identify cells at the origin of basal... 
POPULATION | STEM-CELLS | SONIC HEDGEHOG | EPIDERMIS | HAIR FOLLICLE BULGE | KERATINOCYTES | CANCER | EXPRESSION | HUMAN HOMOLOG | MOUSE SKIN | CELL BIOLOGY | Epithelial Cells - metabolism | Cadherins - metabolism | Receptors, G-Protein-Coupled - metabolism | Skin - metabolism | Cell Count | Ear, External - pathology | Integrin beta4 - metabolism | Tail - pathology | Hair Follicle - pathology | Hedgehog Proteins - genetics | Neoplastic Stem Cells - metabolism | Kruppel-Like Transcription Factors - metabolism | Smoothened Receptor | Neoplastic Stem Cells - pathology | Cell Differentiation | Patched Receptors | Skin - pathology | Keratin-10 - metabolism | Epidermis - metabolism | Epidermis - pathology | RNA, Untranslated | Bacterial Proteins - genetics | Receptors, Cell Surface - metabolism | Epithelial Cells - pathology | Genes, Reporter - genetics | Mice, Transgenic | Carcinoma, Basal Cell - pathology | Mice, Inbred Strains | Clone Cells - metabolism | Keratin-14 - genetics | Carcinoma, Basal Cell - metabolism | Keratin-15 - metabolism | Keratin-19 - genetics | Proteins - genetics | Cell Lineage | Animals | Clone Cells - pathology | Proteins - metabolism | Models, Biological | Hair Follicle - metabolism | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | Mice | Receptors, G-Protein-Coupled - genetics | Integrases - genetics | Keratin-15 - genetics | Luminescent Proteins - metabolism | Basal cell carcinoma | Stem cells | Genetic aspects | Cellular signal transduction | Research | Health aspects | Risk factors
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 09/2010, Volume 130, Issue 9, pp. 2286 - 2294
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e87368
There are several animal models illustrating dry eye pathophysiology. Current study would like to establish an ex vivo tissue culture model for characterizing... 
OCULAR SURFACE EPITHELIUM | MATRIX METALLOPROTEINASES | MUCIN GENE-EXPRESSION | KERATOCONJUNCTIVITIS SICCA | MULTIDISCIPLINARY SCIENCES | CORNEAL EPITHELIAL-CELLS | SQUAMOUS METAPLASIA | LACRIMAL GLAND | FLOW-CYTOMETRIC ANALYSIS | BENZALKONIUM CHLORIDE | INFLAMMATORY MARKERS | Immunohistochemistry | Tumor Necrosis Factor-alpha - metabolism | Epithelial Cells - metabolism | Homeodomain Proteins - metabolism | Humans | Keratin-10 - genetics | Keratin-16 - genetics | Conjunctiva - metabolism | Conjunctiva - pathology | Matrix Metalloproteinase 9 - metabolism | Time Factors | Interleukin-1beta - metabolism | Mucins - metabolism | Repressor Proteins - metabolism | Keratin-10 - metabolism | Gene Expression | Enzyme-Linked Immunosorbent Assay | Mucin-4 - metabolism | Keratin-16 - metabolism | Dry Eye Syndromes - genetics | PAX6 Transcription Factor | Air | Reverse Transcriptase Polymerase Chain Reaction | Mucin-4 - genetics | Keratin-19 - genetics | Eye Proteins - metabolism | Dry Eye Syndromes - metabolism | Mucin 5AC - genetics | Mucin 5AC - metabolism | Keratin-19 - metabolism | Tissue Culture Techniques - methods | Mucins - genetics | Paired Box Transcription Factors - metabolism | Apoptosis | Keratin | Analysis | Mucins | Cell culture | Cornea | Animal models | Media (culture) | Wnt protein | Disease | Laboratories | Science | Tissue culture | Eye | Signal transduction | Epidermal growth factor | Air conditioners | MUC16 gene | Explants | Immunoglobulins | Air exposure | Cultures | Inflammation | Tumor necrosis factor-α | IL-1β | Gelatinase B | Pax6 protein | Metaplasia | Signaling | Mucin | Antibiotics | Stromal cells | Cholera
Journal Article
FASEB Journal, ISSN 0892-6638, 07/2013, Volume 27, Issue 7, pp. 2742 - 2755
Journal Article
Experimental Dermatology, ISSN 0906-6705, 03/2011, Volume 20, Issue 3, pp. 263 - 268
:  Studies have established that autophagy constitutes an efficient process to recycle cellular components and certain proteins. The phenomenon was... 
apoptosis | HaCaT line | Apoptosis | PROTEIN | MOUSE | CELL-DEATH | DERMATOLOGY | GROWTH | CALCIUM | HACAT KERATINOCYTES | SKIN | DEACETYLASE SIRT1 | EXPRESSION | ACUTE PROMYELOCYTIC LEUKEMIA | Sirtuin 1 - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Autophagy - physiology | Autophagy - drug effects | Adenylate Kinase - metabolism | Membrane Proteins - metabolism | Microfilament Proteins - metabolism | Phosphorylation - drug effects | Culture Media, Serum-Free - pharmacology | Cell Differentiation - physiology | Keratin-10 - metabolism | Autophagy-Related Protein 12 | Beclin-1 | Stress, Physiological - physiology | Tumor Suppressor Proteins - metabolism | Adenine - analogs & derivatives | Calcium - pharmacology | Small Ubiquitin-Related Modifier Proteins - metabolism | Cathepsin B - metabolism | Adenine - pharmacology | Keratinocytes - cytology | Apoptosis Regulatory Proteins - metabolism | Protein Precursors - metabolism | Integrin beta1 - metabolism | Transcription Factors - metabolism | Autophagy-Related Protein 8 Family | Autophagy-Related Protein 5 | Keratinocytes - drug effects | Cell Differentiation - drug effects | Keratinocytes - metabolism | Cell Cycle - physiology | Adaptor Proteins, Signal Transducing - metabolism | Cell Cycle - drug effects | bcl-X Protein - metabolism | Cell Line, Transformed | Enzymes | Keratin | Cell death | Trademarks | Cathepsins | Glucose | Dextrose | Integrins | Life Sciences | Human health and pathology | Dermatology
Journal Article
Journal Article
Journal Article
Journal Article
Journal of Cell Science, ISSN 0021-9533, 10/2010, Volume 123, Issue 20, pp. 3566 - 3575
The transcription factor Ets1 is normally expressed in the proliferative layer of stratified epithelium, but expression of Ets1 is significantly upregulated in... 
Chemokine | Transgenic | Mmp | Keratinocyte | EGF ligand | Differentiation | TUMOR PROGRESSION | TRANSCRIPTION FACTOR ETS-1 | SKIN BARRIER FUNCTION | FACTOR RECEPTOR | CELL BIOLOGY | INFLAMMATION | EPIDERMAL-GROWTH-FACTOR | ENVELOPE | SQUAMOUS-CELL CARCINOMA | GENE-EXPRESSION | PROMOTER | Cell Proliferation | Oligonucleotide Array Sequence Analysis | Proto-Oncogene Protein c-ets-1 - metabolism | Keratin-6 - genetics | Immunity, Innate - genetics | Keratin-10 - genetics | Cell Differentiation - genetics | Inflammation - metabolism | Immunity, Innate - physiology | Intermediate Filament Proteins - genetics | Membrane Proteins - metabolism | Cell Differentiation - physiology | Fluorescent Antibody Technique, Indirect | Keratin-10 - metabolism | Epidermis - metabolism | Protein Precursors - genetics | Membrane Proteins - genetics | Cells, Cultured | Mice, Transgenic | Keratin-14 - metabolism | Keratin-5 - genetics | Keratinocytes - cytology | Reverse Transcriptase Polymerase Chain Reaction | Keratin-14 - genetics | Blotting, Western | Keratinocytes - immunology | Protein Precursors - metabolism | Hair Follicle - cytology | Animals | Keratinocytes - metabolism | Hair Follicle - metabolism | Inflammation - genetics | Keratin-5 - metabolism | Proto-Oncogene Protein c-ets-1 - genetics | Chemokines - metabolism | Keratin-6 - metabolism | Mice | Intermediate Filament Proteins - metabolism | Epidermis - cytology
Journal Article
Histopathology, ISSN 0309-0167, 11/2012, Volume 61, Issue 5, pp. 910 - 920
Journal Article
Annual Review of Genetics, ISSN 0066-4197, 11/2017, Volume 51, Issue 1, pp. 123 - 141
Journal Article