X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (304) 304
index medicus (280) 280
keratin-8 - metabolism (280) 280
animals (215) 215
mice (163) 163
female (146) 146
keratin-8 - genetics (128) 128
keratin (122) 122
keratin-18 - metabolism (122) 122
cell biology (116) 116
male (116) 116
expression (102) 102
immunohistochemistry (92) 92
intermediate-filaments (86) 86
cell line, tumor (75) 75
proteins (71) 71
apoptosis (63) 63
biochemistry & molecular biology (61) 61
keratin-8 (61) 61
middle aged (59) 59
phosphorylation (59) 59
keratins - metabolism (56) 56
oncology (56) 56
keratin-18 - genetics (52) 52
epithelial cells - metabolism (49) 49
pathology (49) 49
epithelial-cells (48) 48
cancer (47) 47
cells, cultured (47) 47
adult (46) 46
gene expression (45) 45
analysis (44) 44
aged (43) 43
cells (43) 43
mice, knockout (43) 43
research article (42) 42
differentiation (41) 41
gastroenterology & hepatology (40) 40
mice, transgenic (40) 40
hepatocytes - metabolism (39) 39
cell differentiation (38) 38
disease (38) 38
research (38) 38
intermediate filaments (37) 37
keratins (35) 35
liver (35) 35
cell proliferation (34) 34
in-vitro (34) 34
epithelial cells (32) 32
signal transduction (32) 32
keratins - genetics (31) 31
macromolecular substances (31) 31
article (30) 30
biology (30) 30
developmental biology (30) 30
mutation (30) 30
reverse transcriptase polymerase chain reaction (30) 30
cell line (29) 29
cytoskeleton (29) 29
mice, inbred c57bl (29) 29
transgenic mice (29) 29
intermediate filaments - metabolism (28) 28
keratin-19 - metabolism (28) 28
liver - metabolism (28) 28
medicine (28) 28
rodents (27) 27
biomarkers, tumor - metabolism (26) 26
blotting, western (26) 26
cytokeratin (26) 26
epithelial cells - cytology (26) 26
prognosis (26) 26
stem cells (26) 26
time factors (26) 26
metastasis (25) 25
tumors (25) 25
microscopy, fluorescence (24) 24
identification (23) 23
phenotype (23) 23
activation (22) 22
biomarkers - metabolism (22) 22
breast cancer (22) 22
cytokeratin 8 (22) 22
protein binding (22) 22
rats (22) 22
rna, messenger - metabolism (22) 22
transfection (22) 22
amino acid sequence (21) 21
carcinoma (21) 21
keratin-8 - analysis (21) 21
physiological aspects (21) 21
stem-cells (21) 21
vimentin - metabolism (21) 21
breast neoplasms - pathology (20) 20
epithelial cells - pathology (20) 20
gene expression regulation, neoplastic (20) 20
gene-expression (20) 20
hepatocytes (20) 20
keratin-7 - metabolism (20) 20
molecular sequence data (20) 20
multidisciplinary sciences (20) 20
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


The FEBS Journal, ISSN 1742-464X, 05/2016, Volume 283, Issue 9, pp. 1689 - 1700
Intervertebral discs (IVDs) provide stability and flexibility to the spinal column; however, IVDs, and in particular the nucleus pulposus (NP), undergo a... 
intervertebral disc degeneration | Smad | BMP7 | mesenchymal stem cells | nucleus pulposus | REGENERATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MESENCHYMAL STEM-CELLS | TRANSPLANTATION | CROSS-TALK | LUMBAR-SPINE | IN-VITRO | NUCLEUS PULPOSUS CELLS | DISEASE | GROWTH | DIFFERENTIATION | RNA, Small Interfering - genetics | Bone Morphogenetic Protein 7 - genetics | Humans | Extracellular Matrix - metabolism | Intervertebral Disc Degeneration - metabolism | Intervertebral Disc Degeneration - therapy | Collagen Type II - metabolism | Intervertebral Disc Degeneration - pathology | Lentivirus - metabolism | Glucuronosyltransferase - genetics | Mesenchymal Stromal Cells - cytology | Smad1 Protein - genetics | Lentivirus - genetics | Intervertebral Disc - pathology | Chondrocytes - metabolism | Disease Models, Animal | Intervertebral Disc Degeneration - genetics | SOX9 Transcription Factor - metabolism | Chondrocytes - pathology | Rabbits | Genetic Vectors - chemistry | Signal Transduction | Bone Marrow Cells - cytology | Glycosaminoglycans - metabolism | Keratin-8 - genetics | Gene Expression Regulation | Genetic Vectors - metabolism | Mesenchymal Stromal Cells - metabolism | Intervertebral Disc - metabolism | Aggrecans - metabolism | Smad1 Protein - antagonists & inhibitors | Aggrecans - genetics | Collagen Type II - genetics | Keratin-19 - genetics | Animals | Glucuronosyltransferase - metabolism | Keratin-8 - metabolism | Bone Morphogenetic Protein 7 - metabolism | Smad1 Protein - metabolism | Keratin-19 - metabolism | Extracellular Matrix - pathology | SOX9 Transcription Factor - genetics | Bone Marrow Cells - metabolism | Mesenchymal Stem Cell Transplantation | RNA, Small Interfering - metabolism | Physiological aspects | Bone morphogenetic proteins | Cell differentiation | Analysis | Stem cells | Extracellular matrix | Spine | Rodents | Keratins | Therapy | Surgical implants | Smad protein | Mesenchyme | Collagen (type II) | Sox9 protein | Medical services | Differentiation (biology) | Electrochemical machining | Homeostasis | Nucleus pulposus | Remodeling | Intervertebral discs | Nuclei | Flexibility | Bone marrow | Degeneration | Effectiveness | Stability | Feasibility studies | Implantation | Columns (process) | Survival | Diseases | Overexpression | Biomarkers | Disks | Feasibility | Chondroitin sulfate | Sulfate | Aggrecan | Viability | Bone morphogenetic protein 7
Journal Article
Breast Cancer Research, ISSN 1465-5411, 03/2014, Volume 16, Issue 2, pp. R23 - R23
Journal Article
Nature Cell Biology, ISSN 1465-7392, 09/2010, Volume 12, Issue 9, pp. 876 - 885
Keratins 8 and 18 (K8 and K18) are heteropolymeric intermediate filament phosphoglycoproteins of simple-type epithelia. Mutations in K8 and K18 predispose the... 
CELLS | SIGNALING PATHWAYS | MITOTIC ARREST | KINASE-B | O-GLCNAC MODIFICATION | LIVER-DISEASE | NUCLEOCYTOPLASMIC PROTEINS | LINKED N-ACETYLGLUCOSAMINE | INTERMEDIATE-FILAMENTS | TRANSGENIC MICE | CELL BIOLOGY | Liver - pathology | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Apoptosis - genetics | Glycosylation - drug effects | Pancreas - injuries | Phosphorylation - genetics | Keratins - metabolism | Liver - drug effects | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Antibodies, Monoclonal - immunology | Protein-Serine-Threonine Kinases - metabolism | Chemical and Drug Induced Liver Injury - prevention & control | Antibodies, Monoclonal - pharmacology | Liver - metabolism | Enzyme Inhibitors - pharmacology | Pancreas - pathology | Acetylglucosamine - pharmacology | Mice, Transgenic | Pancreas - metabolism | Mice, Knockout | Phenylcarbamates - pharmacology | fas Receptor - agonists | Chemical and Drug Induced Liver Injury - metabolism | Models, Biological | Cytoskeleton - metabolism | Cytosol - metabolism | Mice | Keratins - genetics | Protein Binding - physiology | Cytosol - drug effects | Hepatocytes - metabolism | Proto-Oncogene Proteins c-akt - genetics | fas Receptor - immunology | Acetylglucosamine - analogs & derivatives | Chemical and Drug Induced Liver Injury - pathology | Hepatocytes - drug effects | Keratins - chemistry | Pancreas - drug effects | beta-N-Acetylhexosaminidases - antagonists & inhibitors | Chemical and Drug Induced Liver Injury - genetics | Glycogen Synthase Kinase 3 - metabolism | Mice, Inbred Strains | Streptozocin - pharmacology | Keratin-18 - genetics | HSP70 Heat-Shock Proteins - metabolism | Protein Kinase C-delta - metabolism | Animals | Keratin-8 - metabolism | Keratin-18 - metabolism | Oximes - pharmacology | Amino Acid Substitution - genetics | Keratin | Liver diseases | Gene mutations | Physiological aspects | Glycosylation | Genetic aspects | Research | Health aspects | Risk factors
Journal Article
PROTEOMICS, ISSN 1615-9853, 04/2017, Volume 17, Issue 7, pp. 1600254 - n/a
Keratin 8/18, a simple epithelia specific keratin pair, is often aberrantly expressed in squamous cell carcinomas (SCC) where its expression is correlated with... 
IPA | Keratin 8 | 18 Phosphorylation | Quantitative phosphoproteomics | Tumorigenic potential | CDC2 Protein Kinase | Phosphorylation | Cyclin-Dependent Kinases - metabolism | Epithelial Cells - metabolism | Cytoskeletal Proteins - genetics | Skin - metabolism | Humans | Gene Expression Regulation, Neoplastic | Phosphoproteins - metabolism | DNA-Binding Proteins - metabolism | Cell Cycle Proteins - genetics | Cytoskeletal Proteins - metabolism | Proteomics - methods | Cyclin-Dependent Kinases - genetics | Protein-Serine-Threonine Kinases - metabolism | Skin - pathology | Eukaryotic Initiation Factors - genetics | Eukaryotic Initiation Factors - metabolism | Keratin-8 - genetics | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Epithelial Cells - pathology | Cortactin - metabolism | Phosphoproteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Transcription Factors - metabolism | Keratin-8 - metabolism | Cortactin - genetics | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Proteins | Keratin | Squamous cell carcinoma | Spreadsheets | Analysis | Development and progression | Skin | Deregulation | Invasiveness | Tumorigenicity | Kinases | Mutants | Skin cancer | Aberration | Cell migration | Cancer
Journal Article
Journal Article
Gut, ISSN 0017-5749, 10/2017, Volume 66, Issue 10, pp. 1748 - 1760
ObjectiveEpidemiological and clinical data indicate that patients suffering from IBD with long-standing colitis display a higher risk to develop colorectal... 
COLORECTAL CANCER | IBD | CELL MATRIX INTERACTION | INTEGRINS | INTESTINAL BARRIER FUNCTION | CELLS | ALPHA-6-BETA-4 INTEGRIN | INFLAMMATION | ABSENCE | EPIDERMOLYSIS-BULLOSA | INTESTINAL BARRIER | GASTROENTEROLOGY & HEPATOLOGY | TUMOR-GROWTH | EXPRESSION | PROMOTES | BETA | Intestinal Mucosa - metabolism | Intestinal Mucosa - physiopathology | Epithelial Cells - metabolism | Colitis - genetics | Colorectal Neoplasms - genetics | B-Lymphocytes | Hemidesmosomes - physiology | Caspase 1 - metabolism | Colitis - pathology | Hemidesmosomes - genetics | Adenocarcinoma - metabolism | Adenocarcinoma - physiopathology | Mucus - metabolism | Adenocarcinoma - genetics | Integrin alpha6beta4 - metabolism | Cytokines - genetics | Colorectal Neoplasms - metabolism | Adaptive Immunity | Severity of Illness Index | Cytokines - metabolism | Signal Transduction | T-Lymphocytes | Lymphocyte Activation | Myeloid Differentiation Factor 88 - genetics | Integrin alpha6 - genetics | Permeability | Colorectal Neoplasms - physiopathology | Basement Membrane - physiopathology | Animals | Colitis - physiopathology | Keratin-8 - metabolism | Keratin-18 - metabolism | Colitis - metabolism | Mice | Homeostasis - genetics | Intestinal Mucosa - pathology | Complications and side effects | Inflammatory bowel diseases | Antibiotics | Colorectal cancer | Dosage and administration | Research | Epidemiology | Risk factors | Adenocarcinoma | Transformation | Animal models | Epithelial cells | Hyperplasia | Colorectal carcinoma | Helper cells | Homeostasis | Genomes | Lymphocytes T | Small intestine | Defects | Metastases | Keratin | Cell activation | Laminin | Intestine | Hemidesmosomes | Tumorigenesis | Colon | Immune system | Dysplasia | Cytokines | Secretion | Inflammation | Patients | Interleukin 18 | Inflammatory bowel disease | Studies | Lymphocytes B | Colitis | Tumors | Life Sciences | Development Biology | Inflammatory Bowel Disease | 1506
Journal Article
Journal Article
Journal Article
Journal Article
Cell Biology International, ISSN 1065-6995, 03/2016, Volume 40, Issue 3, pp. 341 - 353
Primary human hepatocytes are in great demand during drug development and in hepatology. However, both scarcity of tissue supply and donor variability of... 
biotransformation | spheroids | CYP450 | in vitro drug testing | xenobiotics | hepatocytes | Hepatocytes | Xenobiotics | Biotransformation | Spheroids | In vitro drug testing | HEPARG CELL-LINE | LIVER-TISSUE | CYTOCHROME-P450 | TOXICITY | CELL BIOLOGY | IN-VITRO | PRIMARY RAT | ENZYME | HEPG2 CELLS | EXPRESSION | DRUG-METABOLISM | Immunohistochemistry | Humans | Serum Albumin - genetics | Organic Cation Transporter 1 - metabolism | Hepatocytes - metabolism | Spheroids, Cellular - cytology | Organic Cation Transporter 1 - genetics | Hepatocytes - cytology | Glycogen - metabolism | Spectrometry, Mass, Electrospray Ionization | Cytochrome P-450 CYP3A - genetics | Multidrug Resistance-Associated Proteins - genetics | Urea - metabolism | Cell Culture Techniques | Cell Differentiation - physiology | Real-Time Polymerase Chain Reaction | Solute Carrier Organic Anion Transporter Family Member 1b1 - genetics | Keratin-8 - genetics | Spheroids, Cellular - metabolism | Cell Proliferation - physiology | Cells, Cultured | Hep G2 Cells | Pharmaceutical Preparations - metabolism | Keratin-8 - metabolism | Cytochrome P-450 CYP3A - metabolism | Solute Carrier Organic Anion Transporter Family Member 1b1 - metabolism | Pharmaceutical Preparations - analysis | Multidrug Resistance-Associated Proteins - metabolism | Serum Albumin - metabolism | Enzymes | Rodents | Liver | Index Medicus
Journal Article
Cellular Signalling, ISSN 0898-6568, 06/2015, Volume 27, Issue 6, pp. 1110 - 1119
Journal Article