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Cell Stem Cell, ISSN 1934-5909, 09/2012, Volume 11, Issue 3, pp. 401 - 414
The integrity of the epidermis and mucosal epithelia is highly dependent on resident self-renewing stem cells, which makes them vulnerable to physical and... 
MAMMALIAN TARGET | CANCER PATIENTS | RAPAMYCIN | HEAD | AGING PHENOTYPES | MANGANESE SUPEROXIDE-DISMUTASE | STRESS-RESPONSE | TUMOR | NECK | SKIN | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Cell Death - radiation effects | TOR Serine-Threonine Kinases - metabolism | Keratinocytes - radiation effects | Carcinoma, Squamous Cell - pathology | Epithelial Cells - drug effects | Humans | Cellular Senescence - drug effects | Cell Compartmentation - radiation effects | Mucositis - prevention & control | Mouth Mucosa - drug effects | TOR Serine-Threonine Kinases - antagonists & inhibitors | Mouth Mucosa - radiation effects | Mucositis - pathology | Stem Cells - enzymology | Mucositis - enzymology | Cellular Senescence - radiation effects | Cytoprotection - drug effects | Clone Cells | Oxidative Stress - radiation effects | Cell Death - drug effects | Head and Neck Neoplasms - enzymology | Mouth Mucosa - pathology | Keratinocytes - enzymology | Superoxide Dismutase - metabolism | Radiation, Ionizing | Carcinoma, Squamous Cell - enzymology | Epithelial Cells - radiation effects | Cells, Cultured | Stem Cells - radiation effects | Epithelial Cells - pathology | Radiation Injuries - enzymology | Sirolimus - pharmacology | Head and Neck Neoplasms - pathology | Keratinocytes - pathology | Animals | Keratinocytes - drug effects | Radiation Injuries - prevention & control | Epithelial Cells - enzymology | Cell Compartmentation - drug effects | Stem Cells - drug effects | Stem Cells - pathology | Radiation Injuries - pathology | Cell Proliferation - drug effects | Mice | Oxidative Stress - drug effects | Cytoprotection - radiation effects | Cell Proliferation - radiation effects | Index Medicus
Journal Article
Development (Cambridge), ISSN 0950-1991, 05/2016, Volume 143, Issue 10, pp. 1674 - 1687
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 2010, Volume 390, Issue 1, pp. 61 - 69
The potential for colloidal carriers to increase drug bioavailability has spurred a renewed interest in their uptake mechanisms and movement within cells.... 
Nanoparticles | Cell uptake | Cell membrane | Resveratrol | Cell cycle | Nanomedicine | Controlled release | APOPTOSIS | PROTECTION | NLC | DRUG-DELIVERY | EPR | DELIVERY-SYSTEMS | INDUCTION | CANCER | SLN | PHARMACOLOGY & PHARMACY | LEUKEMIA | Stilbenes - administration & dosage | Nanoparticles - chemistry | Humans | Biological Availability | Delayed-Action Preparations - chemistry | Stilbenes - metabolism | Anticarcinogenic Agents - metabolism | Stilbenes - pharmacology | Drug Carriers - chemistry | Anticarcinogenic Agents - pharmacokinetics | Lipids - chemistry | Lecithins - chemistry | Anticarcinogenic Agents - administration & dosage | Delayed-Action Preparations - pharmacology | Metabolism - drug effects | Anticarcinogenic Agents - pharmacology | Poloxamer - chemistry | Drug Carriers - metabolism | Cell Size - drug effects | Keratinocytes - cytology | Static Electricity | Drug Carriers - pharmacology | Necrosis - chemically induced | Cell Shape - drug effects | Particle Size | Delayed-Action Preparations - metabolism | Keratinocytes - drug effects | Keratinocytes - metabolism | Intracellular Space - metabolism | Hydrophobic and Hydrophilic Interactions | Stilbenes - pharmacokinetics | Cell Proliferation - drug effects | Cell Cycle - drug effects | Cell Nucleus - drug effects | Cell Line, Transformed | Microscopy, Fluorescence | Index Medicus
Journal Article
Biomaterials, ISSN 0142-9612, 2016, Volume 84, pp. 25 - 41
Abstract Curcumin (Cur) has been demonstrated to have wide pharmacological window including anti-oxidant and anti-inflammatory properties. However,... 
Advanced Basic Science | Dentistry | Photodegradation | Phototoxicity | Curcumin | Apoptosis/necrosis | Photoprotection | Nanoformulation | ACTIVATION | MATERIALS SCIENCE, BIOMATERIALS | MECHANISM | INDUCED APOPTOSIS | ENGINEERING, BIOMEDICAL | DNA-DAMAGE | MITOCHONDRIA | KERATINOCYTES | DEATH | BCL-2 | SUNLIGHT | BAX | DNA Breaks - drug effects | NIH 3T3 Cells | Reactive Oxygen Species - metabolism | Nanoparticles - chemistry | Apoptosis - drug effects | Apoptosis - radiation effects | Keratinocytes - radiation effects | Membrane Potential, Mitochondrial - radiation effects | Humans | Extracellular Signal-Regulated MAP Kinases - metabolism | Membrane Potential, Mitochondrial - drug effects | RNA, Messenger - metabolism | DNA Breaks - radiation effects | Photosensitizing Agents - pharmacology | Ultraviolet Rays | Protective Agents - pharmacology | Cytoprotection - drug effects | Oxidative Stress - radiation effects | Signal Transduction - radiation effects | Proto-Oncogene Proteins c-akt - metabolism | Keratinocytes - enzymology | Keratinocytes - ultrastructure | Cell Membrane - drug effects | Cell Membrane - radiation effects | Cell Line | Cell Survival - drug effects | Lactic Acid - chemistry | RNA, Messenger - genetics | Curcumin - pharmacology | Absorption, Radiation | Cell Survival - radiation effects | Animals | Cell Cycle Checkpoints - radiation effects | Keratinocytes - drug effects | Signal Transduction - drug effects | Cell Cycle Checkpoints - drug effects | Polyglycolic Acid - chemistry | Drug Liberation | Mice | Molecular Docking Simulation | Oxidative Stress - drug effects | Cytoprotection - radiation effects | Nanoparticles | Genetic research | Analysis | Index Medicus | Biotechnology | Phosphorylation | Cascades | Sunlight | Exposure | Biological | Apoptosis
Journal Article
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, pp. 1560 - 1560
Journal Article
Nanomedicine: Nanotechnology, Biology, and Medicine, ISSN 1549-9634, 2010, Volume 6, Issue 3, pp. 427 - 441
Journal Article
Toxicological Sciences, ISSN 1096-6080, 7/2009, Volume 110, Issue 1, pp. 138 - 155
Journal Article
Cell, ISSN 0092-8674, 2007, Volume 129, Issue 4, pp. 723 - 733
Transcriptional activation of the nuclear receptor RAR by retinoic acid (RA) often leads to inhibition of cell growth. However, in some tissues, RA promotes... 
ACUTE-PROMYELOCYTIC-LEUKEMIA | PPAR-BETA | BREAST-CANCER CELLS | TERATOCARCINOMA STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MAMMARY-CARCINOMA | SYMPATHETIC NEURONS | E-FABP | FATTY-ACIDS | TARGET GENE | BINDING PROTEIN-II | CELL BIOLOGY | Active Transport, Cell Nucleus - physiology | Apoptosis - drug effects | Humans | Transcriptional Activation - drug effects | Cell Survival - genetics | Apoptosis - genetics | Mammary Neoplasms, Experimental - physiopathology | Fatty Acid-Binding Proteins - metabolism | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Receptors, Retinoic Acid - genetics | Cell Nucleus - metabolism | Mammary Neoplasms, Animal - physiopathology | Female | Gene Expression Regulation, Neoplastic - physiology | Mammary Neoplasms, Animal - genetics | Tretinoin - pharmacology | Receptors, Retinoic Acid - drug effects | Cell Survival - drug effects | PPAR-beta - metabolism | Keratinocytes | Receptors, Retinoic Acid - metabolism | Cell Transformation, Neoplastic - metabolism | Fatty Acid-Binding Proteins - genetics | Animals | PPAR-beta - drug effects | Active Transport, Cell Nucleus - drug effects | Mammary Neoplasms, Animal - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Transcriptional Activation - physiology | Cell Transformation, Neoplastic - drug effects | Cell Nucleus - drug effects | Growth | Tretinoin | Index Medicus
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 11/2014, Volume 194, pp. 138 - 147
Journal Article
Biomaterials, ISSN 0142-9612, 2012, Volume 34, Issue 9, pp. 2194 - 2201
Journal Article
Scientific Reports, ISSN 2045-2322, 06/2015, Volume 5, Issue 1, pp. 11596 - 11596
Novel antimicrobials and new approaches to developing them are urgently needed. Repurposing already-approved drugs with well-characterized toxicology and... 
SOFT-TISSUE INFECTIONS | IN-VITRO | ANTIBIOTICS | CA-MRSA SKIN | ANTIOXIDANT | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | COMPOUND | DRUGS | AUREUS | EXPRESSION | Methicillin Resistance - drug effects | Skin - microbiology | Skin - metabolism | Humans | Biofilms - growth & development | Host-Pathogen Interactions - drug effects | Organoselenium Compounds - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Microbial Sensitivity Tests | Female | Staphylococcal Infections - microbiology | Biofilms - drug effects | Methicillin-Resistant Staphylococcus aureus - physiology | Cell Survival - drug effects | Staphylococcal Infections - drug therapy | Methicillin-Resistant Staphylococcus aureus - drug effects | Cells, Cultured | Drug Repositioning | Azoles - pharmacology | Mupirocin - pharmacology | Drug Synergism | Daptomycin - pharmacology | Bacterial Toxins - metabolism | Methicillin-Resistant Staphylococcus aureus - metabolism | Animals | Keratinocytes - drug effects | Anti-Bacterial Agents - pharmacology | Mice, Inbred BALB C | Skin - drug effects | Cytokines | Therapeutic applications | Clinical isolates | Staphylococcus infections | Protein biosynthesis | Antimicrobial agents | Inflammation | Vancomycin | Tumor necrosis factor-α | Drug resistance | Bactericidal activity | Methicillin | Interleukin 6 | Biofilms | Interleukin 1 | Tumor necrosis factor-TNF | Skin diseases | Monocyte chemoattractant protein 1 | Index Medicus
Journal Article