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Journal of Clinical Investigation, ISSN 0021-9738, 07/2012, Volume 122, Issue 7, pp. 2482 - 2498
Filamentous fungi are a common cause of blindness and visual impairment worldwide. Using both murine model systems and in vitro human neutrophils, we found... 
TRANSCRIPTIONAL REGULATOR | MEDICINE, RESEARCH & EXPERIMENTAL | ASPERGILLUS-FUMIGATUS | OXIDATIVE STRESS | RESPIRATORY BURST | CANDIDA-ALBICANS | BETA-GLUCAN | GLIOTOXIN PRODUCTION | CHRONIC GRANULOMATOUS-DISEASE | MICROBIAL KERATITIS | FUSARIUM KERATITIS | Keratitis - immunology | Keratitis - pathology | Reactive Oxygen Species - metabolism | Oxidative Stress | Antioxidants - metabolism | Humans | NADPH Oxidases - metabolism | Neutrophil Infiltration | Aspergillosis - pathology | Fusarium - physiology | NADPH Oxidases - genetics | Thioredoxins - metabolism | Cornea - pathology | Fusarium - metabolism | Cornea - microbiology | Neutrophils - enzymology | Fusarium - enzymology | Aspergillus flavus - physiology | Mice, Knockout | CD18 Antigens - metabolism | Host-Pathogen Interactions | Antioxidants - physiology | Aspergillosis - microbiology | Fusariosis - immunology | Fusariosis - pathology | Mice | Enzyme Activation | Fusariosis - microbiology | Nitric Oxide Synthase Type II - metabolism | Aspergillus flavus - metabolism | Keratitis - microbiology | Aspergillus fumigatus - enzymology | Superoxide Dismutase - physiology | Aspergillus fumigatus - physiology | Aspergillus fumigatus - metabolism | Neutrophils - microbiology | Superoxide Dismutase - metabolism | Transcription Factors - physiology | Mice, Inbred C57BL | Cells, Cultured | Neutrophils - immunology | Microbial Viability | Aspergillus flavus - enzymology | Transcription Factors - metabolism | Fungal Proteins - physiology | Animals | Nitric Oxide - metabolism | Aspergillosis - immunology | Fungal Proteins - metabolism | Peroxidase - metabolism | Fungi | Neutrophils | Physiological aspects | Mycoses | Research | Drug therapy | Health aspects
Journal Article
Nature Cell Biology, ISSN 1465-7392, 01/2016, Volume 18, Issue 2, pp. 168 - 180
Chronic inflammation is associated with a variety of pathological conditions in epithelial tissues, including cancer, metaplasia and aberrant wound healing. In... 
FIBROSIS | STEM-CELLS | ACTIVATION | YAP/TAZ | SQUAMOUS METAPLASIA | EXTRACELLULAR-MATRIX | T-CELL | DIFFERENTIATION | SUPPRESSION | CANCER | CELL BIOLOGY | Administration, Ophthalmic | Keratitis - pathology | Epithelial Cells - metabolism | Mechanotransduction, Cellular - drug effects | Epithelial Cells - drug effects | Humans | Corneal Injuries - genetics | Extracellular Matrix - metabolism | Epithelium, Corneal - pathology | Phosphoproteins - metabolism | Stem Cells - metabolism | Epithelium, Corneal - injuries | Corneal Injuries - metabolism | Receptor, Notch1 - deficiency | Transfection | Time Factors | Swine | HEK293 Cells | Inflammation Mediators - metabolism | Epithelium, Corneal - drug effects | Anti-Inflammatory Agents - administration & dosage | Wnt Signaling Pathway | Disease Models, Animal | Keratitis - genetics | Corneal Injuries - pathology | Keratitis - prevention & control | Mice, Inbred C57BL | Epithelial Cells - pathology | Phosphoproteins - genetics | Transcription Factors - genetics | beta Catenin - metabolism | beta Catenin - genetics | Mice, Knockout | Transcription Factors - metabolism | Regeneration - drug effects | Animals | Cell Differentiation - drug effects | Adaptor Proteins, Signal Transducing - genetics | Keratitis - metabolism | Epithelium, Corneal - metabolism | Stem Cells - drug effects | Stem Cells - pathology | Adaptor Proteins, Signal Transducing - metabolism | Receptor, Notch1 - genetics | Chronic Disease | Physiological aspects | Cellular signal transduction | Inflammation | Epithelium | Health aspects
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 06/2018, Volume 200, Issue 11, pp. 3711 - 3719
Immune privilege helps protect the cornea from damaging inflammation but can also impair pathogen clearance from this mucosal surface. Programmed death-ligand... 
SURVIVAL | RESPONSES | SIMPLEX-VIRUS TYPE-1 | REPLICATION | RESISTANCE | MONOCYTES | NEUTROPHILS | KERATITIS | INFECTION | IMMUNOLOGY | T-CELLS | Epithelial Cells - metabolism | Leukocyte Common Antigens - metabolism | Dendritic Cells - immunology | Cornea - immunology | Monocytes - metabolism | Monocytes - immunology | Leukocyte Common Antigens - immunology | Macrophages - virology | Killer Cells, Natural - immunology | Female | Herpesvirus 1, Human - immunology | Dendritic Cells - virology | Epithelium, Corneal - immunology | Neutrophils - metabolism | Dendritic Cells - metabolism | Macrophages - immunology | Cornea - virology | Killer Cells, Natural - virology | Mice, Inbred C57BL | Neutrophils - immunology | B7-H1 Antigen - immunology | Neutrophils - virology | Herpes Simplex - immunology | Herpes Simplex - metabolism | Cornea - metabolism | Monocytes - virology | B7-H1 Antigen - metabolism | Herpes Simplex - virology | Macrophages - metabolism | Animals | Epithelial Cells - immunology | Epithelial Cells - virology | Epithelium, Corneal - metabolism | Mice | Killer Cells, Natural - metabolism | Epithelium, Corneal - virology | Cornea | Leukocyte migration | PD-1 protein | Epithelial cells | Mucosa | Immune clearance | Population studies | Macrophages | B7 antigen | CD45 antigen | Rodents | Bone marrow | Chimeras | Lesions | Immune system | Dendritic cells | Leukocytes (neutrophilic) | Inflammation | T cell receptors | Epithelium | Monocytes | PD-L1 protein | Immune privilege | Cell migration | Apoptosis
Journal Article
Journal of Immunology, ISSN 0022-1767, 06/2013, Volume 190, Issue 11, pp. 5649 - 5658
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 01/2010, Volume 207, Issue 1, pp. 101 - 115
Inflammatory lymphangiogenesis plays a crucial role in the development of inflammation and transplant rejection. The mechanisms of inflammatory... 
MEDICINE, RESEARCH & EXPERIMENTAL | HERPES-SIMPLEX-VIRUS | INFLAMMATORY LYMPHANGIOGENESIS | STROMAL KERATITIS | ADENOSINE A(2A) RECEPTORS | FACTOR-C | IMMUNE PRIVILEGE | TRANSCRIPTION FACTOR SP1 | IMMUNOLOGY | NF-KAPPA-B | TYPE-1 INFECTION | ENDOTHELIAL GROWTH-FACTOR | Corneal Neovascularization - immunology | Inflammation - pathology | Vascular Endothelial Growth Factor A - biosynthesis | Antigens, Viral - metabolism | Cornea - immunology | Corneal Neovascularization - genetics | Vascular Endothelial Growth Factor Receptor-2 - immunology | Vascular Endothelial Growth Factor A - genetics | Herpes Simplex - genetics | Cell Movement - genetics | Vascular Endothelial Growth Factor Receptor-3 - immunology | Vascular Endothelial Growth Factor Receptor-2 - genetics | Cell Movement - immunology | Signal Transduction - immunology | Inflammation - metabolism | Lymphatic Vessels - metabolism | Herpesvirus 1, Human - immunology | Cornea - pathology | Corneal Neovascularization - virology | Macrophages - immunology | Cornea - virology | Herpesvirus 1, Human - metabolism | Macrophages - pathology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Inflammation - virology | Lymphatic Vessels - immunology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Mice, Transgenic | Vascular Endothelial Growth Factor A - immunology | Inflammation - immunology | Signal Transduction - genetics | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Herpes Simplex - immunology | Herpes Simplex - metabolism | Antigens, Viral - immunology | Cornea - metabolism | Macrophages - metabolism | Animals | Corneal Neovascularization - metabolism | Herpes Simplex - pathology | Lymphatic Vessels - pathology | Inflammation - genetics | Mice
Journal Article
Journal Article
Infection and Immunity, ISSN 0019-9567, 07/2011, Volume 79, Issue 7, pp. 2709 - 2716
Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
INFECTIOUS DISEASES | OCULAR INFECTION | ACTIVATION | MACROPHAGES | PROMOTES RESISTANCE | POLYMORPHONUCLEAR NEUTROPHIL INFLUX | KERATITIS | IMMUNOLOGY | EXPRESSION | MYELOID CELLS-1 | NEGATIVE REGULATOR | CUTTING EDGE | Interleukin-1 Receptor-Like 1 Protein | Pseudomonas aeruginosa - immunology | Eye Infections, Bacterial - immunology | Keratitis - immunology | Receptors, Interleukin - biosynthesis | Membrane Glycoproteins - metabolism | Keratitis - microbiology | Humans | Middle Aged | Cornea - immunology | Antibodies | Male | Th2 Cells - immunology | Neutrophil Infiltration | Th1 Cells - immunology | Recombinant Fusion Proteins - metabolism | Pseudomonas Infections - metabolism | Pseudomonas aeruginosa - metabolism | Adult | Female | Membrane Glycoproteins - immunology | Receptors, Immunologic - immunology | Toll-Like Receptors - metabolism | Eye Infections, Bacterial - metabolism | Cytokines - metabolism | Signal Transduction | Eye Infections, Bacterial - genetics | Mice, Inbred C57BL | Toll-Like Receptors - immunology | Neutrophils - immunology | Receptors, Interleukin-1 - biosynthesis | Reverse Transcriptase Polymerase Chain Reaction | Pseudomonas Infections - genetics | Pseudomonas Infections - immunology | Cornea - metabolism | Animals | Triggering Receptor Expressed on Myeloid Cells-1 | Pseudomonas aeruginosa - genetics | Keratitis - metabolism | Aged | Mice | beta-Defensins - biosynthesis | Cytokines - biosynthesis | Receptors, Immunologic - metabolism | Host Response and Inflammation
Journal Article
Journal Article
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 02/2013, Volume 54, Issue 2, pp. 1227 - 1234
Journal Article
Journal Article
Molecular Vision, ISSN 1090-0535, 01/2013, Volume 19, pp. 85 - 99
Journal Article