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PLoS Medicine, ISSN 1549-1277, 2006, Volume 3, Issue 7, pp. 1152 - 1164
Background: The autoimmune regulator (AIRE) gene influences thymic self-tolerance induction. In autoimmune polyendocrinopathy syndrome type 1 (APS1; OMIM... 
DIABETES-MELLITUS | MYASTHENIA-GRAVIS PATIENTS | MEDICINE, GENERAL & INTERNAL | INTERFERON-ALPHA | SYNDROME TYPE-I | NEUTRALIZING ANTIBODIES | DENDRITIC CELLS | IFN-GAMMA | DISEASE | EXPRESSION | T-CELLS | Antibody Specificity | Polyendocrinopathies, Autoimmune - diagnosis | Alopecia - immunology | Autoantibodies - blood | Dendritic Cells - immunology | Humans | Middle Aged | Child, Preschool | Male | Interferon Type I - immunology | Interferons - immunology | Lymphocyte Subsets - immunology | Palatine Tonsil - immunology | Autoimmunity - immunology | Polyendocrinopathies, Autoimmune - genetics | Thymoma - immunology | HLA Antigens - immunology | Genotype | Polyendocrinopathies, Autoimmune - immunology | Lymphoid Tissue - pathology | Thymus Gland - ultrastructure | Norway - epidemiology | Adolescent | Cell Line, Tumor | Candidiasis, Chronic Mucocutaneous - etiology | Interferons - physiology | Finland - epidemiology | Self Tolerance - immunology | Transcription Factors - deficiency | Alopecia - etiology | Neutralization Tests | Keratoconjunctivitis - immunology | Keratoconjunctivitis - etiology | Myasthenia Gravis - etiology | Lymphoid Tissue - immunology | Thymus Neoplasms - immunology | Antigen Presentation | Immunoglobulin G - immunology | Self Tolerance - genetics | Interleukins - immunology | Adult | Female | Candidiasis, Chronic Mucocutaneous - immunology | Transcription Factors - genetics | Polyendocrinopathies, Autoimmune - epidemiology | Interferon-alpha - immunology | Thymus Neoplasms - complications | Autoantibodies - immunology | Interferons - classification | Thymus Gland - immunology | Myasthenia Gravis - immunology | Thymoma - complications | Development and progression | Genetic aspects | Research | Autoimmune diseases | Allergy | Immunology | Gene Therapy | Genomics | Autoimmune Diseases | Genetics | Immunology and Allergy
Journal Article
Immunology Letters, ISSN 0165-2478, 2011, Volume 141, Issue 1, pp. 1 - 9
Highlights ► Etiology and many aspects of the pathogenesis of Sjögren's syndrome are still elusive. ► Today's therapies rely merely on relieving the symptoms.... 
Allergy and Immunology | Autoimmunity | Autoantibodies | Type I interferon | Dendritic cells | Sjögren's syndrome | Sjogren's syndrome | SYSTEMIC-LUPUS-ERYTHEMATOSUS | I INTERFERON SYSTEM | LYMPHOID ORGANIZATION | IMMUNOLOGY | CYTOKINE EXPRESSION | PLASMACYTOID DENDRITIC CELLS | TISSUE INFLAMMATION | REGULATORY T-CELLS | AUTOANTIGEN RO52 | MONOCLONAL-ANTIBODIES | MINOR SALIVARY-GLANDS | Salivary Glands - immunology | Salivary Glands - pathology | OX40 Ligand - genetics | Dendritic Cells - immunology | Humans | Sjogren's Syndrome - immunology | Keratoconjunctivitis Sicca - immunology | T-Lymphocytes, Regulatory - immunology | Keratoconjunctivitis Sicca - complications | Autoimmunity - immunology | Peptide Fragments - immunology | Ribonucleoproteins - immunology | Trans-Activators - genetics | STAT4 Transcription Factor - immunology | Trans-Activators - immunology | Receptors, Muscarinic - genetics | Sjogren's Syndrome - pathology | Interferon Regulatory Factors - genetics | Receptors, Muscarinic - immunology | Autoantibodies - immunology | Interferon Regulatory Factors - immunology | Animals | OX40 Ligand - immunology | Sjogren's Syndrome - diagnosis | Autoantigens - immunology | Keratoconjunctivitis Sicca - pathology | Salivary Glands - physiopathology | Biomarkers | Th17 Cells - immunology | STAT4 Transcription Factor - genetics | Mice | Development and progression | Biological response modifiers | Rheumatoid arthritis
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 10053 - 10
In a transgenic mouse line hK14mIL33tg, with the expression of interleukin-33 (IL-33) driven by a keratin 14 promoter, keratoconjunctivitis developed... 
INTERLEUKIN-33 | ALLERGIC CONJUNCTIVITIS | EOTAXIN | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | Interleukin-13 - immunology | Keratoconjunctivitis - immunology | Interleukin-5 - genetics | Epithelium, Corneal - pathology | Eosinophils - immunology | Interleukin-33 - immunology | Founder Effect | Conjunctiva - pathology | Interleukin-13 - genetics | Lymphocytes - immunology | Basophils - pathology | Basophils - immunology | Keratoconjunctivitis - pathology | Eosinophils - pathology | Interleukin-4 - genetics | Epithelium, Corneal - immunology | Disease Models, Animal | Tryptases - genetics | Tryptases - immunology | Mast Cells - immunology | Promoter Regions, Genetic | Conjunctiva - immunology | Signal Transduction | Membrane Proteins - genetics | Gene Expression Regulation | Keratoconjunctivitis - genetics | Chemokine CCL11 - genetics | Membrane Proteins - immunology | Mice, Transgenic | Immunity, Innate | Keratin-14 - genetics | Interleukin-5 - immunology | Interleukin-4 - immunology | Interleukin-33 - genetics | Lymphocytes - pathology | Animals | Mast Cells - pathology | Keratin-14 - immunology | Chemokine CCL11 - immunology | Mice | Blepharitis | Cornea | Lymphoid cells | Leukocytes (eosinophilic) | Transgenic mice | Interleukin 13 | Conjunctiva | Epithelium | Atopy | Keratin | Keratoconjunctivitis | Interleukin 4 | Interleukin 5 | Rodents | Mast cells | Leukocytes (basophilic)
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2014, Volume 193, Issue 10, pp. 5264 - 5272
The Th1-associated chemokines CXCL9, CXCL10, and CXCL11 coordinate migration of CXCR3(+) Th1 cells. The objective of this study was to evaluate the role of the... 
OCULAR SURFACE | MATRIX METALLOPROTEINASES | ACTIVATION | INTERFERON-GAMMA | NK CELLS | TOLL-LIKE RECEPTOR | CORNEAL EPITHELIUM | IMMUNOLOGY | INFLAMMATORY CYTOKINES | LACRIMAL KERATOCONJUNCTIVITIS | T-CELLS | Chemokine CXCL11 - genetics | Antigens, Ly - genetics | NK Cell Lectin-Like Receptor Subfamily K - immunology | Homeodomain Proteins - immunology | Adoptive Transfer | Epithelium, Corneal - pathology | Xerophthalmia - genetics | T-Lymphocytes - transplantation | Conjunctiva - pathology | Gene Deletion | Chemokine CXCL10 - immunology | Female | Chemokine CXCL11 - immunology | Interferon-gamma - genetics | T-Lymphocytes - pathology | Epithelium, Corneal - immunology | Disease Models, Animal | Xerophthalmia - pathology | Conjunctiva - immunology | Membrane Proteins - genetics | Desiccation | Mice, Inbred C57BL | Gene Expression Regulation | Membrane Proteins - immunology | Chemokine CXCL9 - immunology | Immunity, Innate | NK Cell Lectin-Like Receptor Subfamily K - genetics | Chemokine CXCL9 - genetics | NK Cell Lectin-Like Receptor Subfamily B - immunology | Homeodomain Proteins - genetics | Mice, Knockout | Antibodies - pharmacology | Animals | NK Cell Lectin-Like Receptor Subfamily B - antagonists & inhibitors | Antigens, Ly - immunology | NK Cell Lectin-Like Receptor Subfamily B - genetics | Chemokine CXCL10 - genetics | Interferon-gamma - immunology | T-Lymphocytes - immunology | Mice | Xerophthalmia - immunology | NK cell receptor ligands | NK cells | chemokines | Dry eye
Journal Article
Autoimmunity Reviews, ISSN 1568-9972, 2004, Volume 3, Issue 3, pp. 175 - 182
Sjögren's syndrome (SS) is a chronic organ-specific autoimmune disease characterized by lymphocytic infiltration into the salivary and lacrimal glands. About... 
Malignant lymphoma | MALT (mucosa-associated lymphoid tissue) lymphoma | Monoclonal proliferation | Lymphoaggressive disorder | Lymphoepithelial lesion | RHEUMATOID-ARTHRITIS | monoclonal proliferation | SYSTEMIC LUPUS-ERYTHEMATOSUS | MALIGNANT-LYMPHOMA | SJORGRENS SYNDROME | IMMUNOLOGY | lymphoaggressive disorder | LYMPHOID-TISSUE LYMPHOMA | lymphoepithelial lesion | LABIAL SALIVARY-GLANDS | B-CELL LYMPHOMA | INCREASED RISK | SICCA SYNDROME | malignant lymphoma | HELICOBACTER-PYLORI | Intestinal Mucosa - metabolism | Liver - pathology | Cell Proliferation | Proto-Oncogene Proteins c-bcl-2 - immunology | Keratoconjunctivitis Sicca - etiology | Kidney - pathology | Humans | Kidney - immunology | Sjogren's Syndrome - immunology | Sjogren's Syndrome - metabolism | CD40 Ligand - immunology | Keratoconjunctivitis Sicca - immunology | Lymphoma - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Liver - immunology | CD40 Antigens - metabolism | CD40 Ligand - metabolism | T-Lymphocytes - metabolism | Intestinal Mucosa - immunology | Lymphoma - pathology | B-Lymphocytes - pathology | T-Lymphocytes - pathology | B-Lymphocytes - metabolism | Skin - pathology | Cytokines - immunology | Skin - immunology | Lung - pathology | Sjogren's Syndrome - pathology | Lymphoma - immunology | Tumor Suppressor Protein p53 - metabolism | Tumor Suppressor Protein p53 - immunology | Hematopoiesis - immunology | B-Lymphocytes - immunology | Lymphoma - etiology | Keratoconjunctivitis Sicca - pathology | T-Lymphocytes - immunology | Sjogren's Syndrome - complications | CD40 Antigens - immunology | Lung - immunology | Intestinal Mucosa - pathology
Journal Article
The Journal of Immunology, ISSN 0022-1767, 02/2009, Volume 182, Issue 3, pp. 1247 - 1252
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e36822
Journal Article