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BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 09/2018, Volume 1863, Issue 9, pp. 968 - 979
Gestational diabetes mellitus (GDM) is associated with excessive oxidative stress which may affect placental vascular function. Cholesterol homeostasis is... 
GDM | Oxidative stress | Human fetoplacental endothelial cells | Cholesterol metabolism | Oxysterols | ABCA1 | CELLS | LIVER-X RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOW-DENSITY-LIPOPROTEIN | CELL BIOLOGY | EFFLUX | BIOPHYSICS | FETAL | PHOSPHOLIPID TRANSFER PROTEIN | BLOOD | Diabetes, Gestational - metabolism | Oxidative Stress | Humans | Fetus - metabolism | Fetus - pathology | Endothelium, Vascular - drug effects | ATP Binding Cassette Transporter, Sub-Family G, Member 1 - metabolism | ATP Binding Cassette Transporter 1 - metabolism | Case-Control Studies | Diabetes, Gestational - genetics | Hydroxymethylglutaryl CoA Reductases - metabolism | Sterol O-Acyltransferase - metabolism | Adult | Female | Diabetes, Gestational - pathology | Ketocholesterols - pharmacology | Endothelial Cells - metabolism | Gene Expression Regulation | Liver X Receptors - metabolism | Cholesterol - metabolism | Hydroxycholesterols - pharmacology | Placenta - metabolism | Pregnancy | Placenta - blood supply | Fetus - blood supply | Endothelium, Vascular - metabolism | Lipid Metabolism - drug effects | Placenta - pathology | Cholesterol - pharmacology | Endothelium, Vascular - pathology | Hydroxycholesterols - metabolism | Sterol O-Acyltransferase - genetics | Primary Cell Culture | ATP Binding Cassette Transporter, Sub-Family G, Member 1 - genetics | Endothelial Cells - pathology | Hydroxymethylglutaryl CoA Reductases - genetics | Homeostasis - genetics | Ketocholesterols - metabolism | Liver X Receptors - genetics | ATP Binding Cassette Transporter 1 - genetics | Endothelial Cells - drug effects | Analysis | Physiological aspects | Homeostasis | Diabetes in pregnancy | Glucose tolerance tests | Cholesterol | Endothelium
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 12/2004, Volume 24, Issue 24, pp. 10703 - 10717
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 03/2013, Volume 53, pp. 205 - 213
► This study showed lipid in marine fish muscle was reduced in presence of oxidant. ► Oxidized lipid products in fish muscle elevated when exposed to hydrogen... 
Isoprostanes | Cholesterol oxidation products | Hydrogen peroxide | EPA | Medaka | DHA | HETE | METABOLITES | FOOD SCIENCE & TECHNOLOGY | BIOMARKERS | HYDROXYEICOSATETRAENOIC ACIDS | F-2-ISOPROSTANES | PLASMA | DOCOSAHEXAENOIC ACID | IN-VIVO | DISEASE | TOXICOLOGY | CHROMATOGRAPHY-MASS SPECTROMETRY | HUMAN URINE | Arachidonic Acid - metabolism | Reactive Oxygen Species - metabolism | Oxidative Stress | Hydrogen Peroxide | Cytochrome P-450 Enzyme System - metabolism | Male | F2-Isoprostanes - metabolism | Oryzias - metabolism | Lipoxygenase - metabolism | Isoprostanes - metabolism | Hydroxyeicosatetraenoic Acids - analysis | Cholesterol - analysis | Hydroxycholesterols - analysis | Arachidonic Acid - analysis | Female | Isoprostanes - analysis | Neuroprostanes - analysis | Oxidation-Reduction | Neuroprostanes - metabolism | Biomarkers - analysis | Eicosapentaenoic Acid - metabolism | F2-Isoprostanes - analysis | Food Handling - methods | Ketocholesterols - analysis | Antioxidants - pharmacology | Cholesterol - metabolism | Docosahexaenoic Acids - analysis | Hydroxyeicosatetraenoic Acids - metabolism | Animals | Docosahexaenoic Acids - blood | Hydroxycholesterols - metabolism | Eicosapentaenoic Acid - analysis | Lipid Peroxidation | Ketocholesterols - metabolism | Docosahexaenoic Acids - metabolism | Oxidative stress | Marine biology
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 06/2014, Volume 71, pp. 1 - 15
Oxysterol is associated with the induction of endothelial oxidative stress and impaired endothelial function. Mitochondria play a central role in oxidative... 
miRNA | Endothelial function | Oxysterol | 7-KC | IDH2 | REDOX STATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ATHEROSCLEROSIS | MECHANISMS | HIGH-DENSITY-LIPOPROTEIN | PLASMA | MESSENGER-RNA | CHOLESTEROL OXIDATION-PRODUCTS | GLUTATHIONE | ENDOCRINOLOGY & METABOLISM | DYSFUNCTION | OXYSTEROLS | Glutathione - metabolism | Atherosclerosis - genetics | Humans | Argonaute Proteins - antagonists & inhibitors | Male | MicroRNAs - metabolism | Aorta - metabolism | Isocitrate Dehydrogenase - antagonists & inhibitors | RNA, Messenger - metabolism | Eukaryotic Initiation Factors - antagonists & inhibitors | Cattle | RNA, Messenger - antagonists & inhibitors | NADP - metabolism | 3' Untranslated Regions | Eukaryotic Initiation Factors - genetics | Eukaryotic Initiation Factors - metabolism | Ketocholesterols - pharmacology | Argonaute Proteins - metabolism | Atherosclerosis - pathology | Argonaute Proteins - genetics | Oxidation-Reduction | Signal Transduction | Endothelial Cells - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Gene Expression Regulation | Isocitrate Dehydrogenase - genetics | Mitochondria - metabolism | Mitochondria - drug effects | Atherosclerosis - metabolism | Aorta - pathology | Animals | Isocitrate Dehydrogenase - metabolism | Mice | MicroRNAs - genetics | Endothelial Cells - pathology | Ketocholesterols - metabolism | Endothelial Cells - drug effects | Enzymes | MicroRNA | Analysis | Atherosclerosis | Physiological aspects | Development and progression | Mitochondrial DNA | Endothelium
Journal Article
FEBS Journal, ISSN 1742-464X, 06/2005, Volume 272, Issue 12, pp. 3093 - 3104
Oxysterols, and particularly 7-ketocholesterol, appear to be strongly involved in the physiopathology of atherosclerosis. These molecules are suspected to be... 
THP-1 cells | Signal transduction | 7-Ketocholesterol | Calcium | Apoptosis | BCL-2 FAMILY-MEMBER | calcium | PROTEIN | signal transduction | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIM | apoptosis | INDUCTION | MAP KINASE ACTIVATION | SIGNALING PATHWAY | 7-ketocholesterol | ENDOTHELIAL-CELLS | SMOOTH-MUSCLE-CELLS | CHOLESTEROL OXIDES | Phosphorylation | Apoptosis - drug effects | Calcium - metabolism | Protein-Tyrosine Kinases - metabolism | Humans | Monocytes - metabolism | Protein Transport - drug effects | Carrier Proteins - drug effects | Focal Adhesion Kinase 2 | Proto-Oncogene Proteins c-bcl-2 - metabolism | Bcl-2-Like Protein 11 | Dyneins - drug effects | Membrane Proteins - metabolism | Dyneins - metabolism | Ketocholesterols - pharmacology | Proto-Oncogene Proteins - metabolism | MAP Kinase Kinase 1 - antagonists & inhibitors | Proto-Oncogene Proteins - drug effects | Signal Transduction | Cells, Cultured | Enzyme Inhibitors - pharmacology | MAP Kinase Kinase 1 - metabolism | MAP Kinase Kinase 2 - metabolism | Discoidin Domain Receptor 1 | Enzyme Activation - drug effects | Receptor Protein-Tyrosine Kinases - metabolism | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Mitogen-Activated Protein Kinase 3 - metabolism | MAP Kinase Kinase 2 - antagonists & inhibitors | Proto-Oncogene Proteins c-bcl-2 - drug effects | Membrane Proteins - drug effects | Apoptosis - physiology | bcl-Associated Death Protein | Ketocholesterols - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 12/2016, Volume 101, pp. 317 - 324
Journal Article
Investigative Ophthalmology & Visual Science, ISSN 0146-0404, 02/2009, Volume 50, Issue 2, pp. 523 - 532
PURPOSE. 7-Ketocholesterol is a highly toxic oxysterol found in abundance in atherosclerotic plaques and is believed to play a critical role in... 
IN-VITRO | ATHEROSCLEROTIC PLAQUES | EPITHELIAL-CELLS | LOW-DENSITY-LIPOPROTEIN | OPHTHALMOLOGY | BRUCHS MEMBRANE | LIVER-X-RECEPTORS | NF-KAPPA-B | FACTOR GENE | ENDOTHELIAL GROWTH-FACTOR | BIOLOGICAL-SYSTEMS | Cholesterol Esters - metabolism | Retinal Pigment Epithelium - metabolism | Vascular Endothelial Growth Factor A - biosynthesis | Retina - metabolism | Humans | Endothelium, Vascular - drug effects | NF-kappa B - metabolism | Macaca mulatta | Chromatography, High Pressure Liquid | RNA, Messenger - metabolism | Vascular Endothelial Growth Factor A - genetics | Immunoenzyme Techniques | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Liver X Receptors | Mass Spectrometry | Orphan Nuclear Receptors | Retinal Pigment Epithelium - drug effects | Ketocholesterols - pharmacology | Cell Line | DNA-Binding Proteins - antagonists & inhibitors | Enzyme-Linked Immunosorbent Assay | Cell Survival | RNA, Small Interfering - pharmacology | Lipoproteins, LDL - pharmacology | Lipid Metabolism | Receptors, Cytoplasmic and Nuclear - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Animals | Choroidal Neovascularization - metabolism | Endothelium, Vascular - metabolism | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Bruch Membrane - metabolism | Retina - pathology | Ketocholesterols - metabolism | Index Medicus
Journal Article
Journal Article