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BBA - Proteins and Proteomics, ISSN 1570-9639, 01/2018, Volume 1866, Issue 1, pp. 88 - 96
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 12/2012, Volume 29, Issue 12, pp. 3486 - 3498
Journal Article
Journal Article
Journal Article
Biochemistry, ISSN 0006-2960, 03/2016, Volume 55, Issue 7, pp. 1058 - 1069
Membrane-bound cytochrome P4503A4 (CYP3A4) is the major source of enzymatic drug metabolism. Although several structural models of CYP3A4 in various ligand... 
EXCHANGE MASS-SPECTROMETRY | PHOSPHOLIPID-BILAYER NANODISCS | PROTEIN | 3A4 | BIOCHEMISTRY & MOLECULAR BIOLOGY | STATE | CHANNELS | BINDING | RECONSTITUTION | RESIDUES | Cytochrome P-450 CYP3A Inhibitors - pharmacology | Membrane Microdomains - metabolism | Protein Unfolding - drug effects | Humans | Enzyme Stability - drug effects | Phosphatidylcholines - metabolism | Recombinant Fusion Proteins - metabolism | Ketoconazole - pharmacology | Apolipoprotein A-I - genetics | Deuterium Exchange Measurement | Cytochrome P-450 CYP3A - genetics | Cytochrome P-450 CYP3A - chemistry | Protein Engineering | Membrane Proteins - metabolism | Peptide Fragments - genetics | Apolipoprotein A-I - chemistry | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Peptide Fragments - metabolism | Membrane Proteins - genetics | Membrane Microdomains - chemistry | Models, Molecular | Recombinant Proteins - chemistry | Apolipoprotein A-I - metabolism | Phosphatidylcholines - chemistry | Recombinant Fusion Proteins - chemistry | Peptide Fragments - chemistry | Membrane Proteins - chemistry | Cytochrome P-450 CYP3A - metabolism | Membrane Microdomains - drug effects | Calorimetry, Differential Scanning | Ligands | Protein Conformation | Lipid Bilayers - chemistry | Lipid Bilayers - metabolism | Molecular dynamics | Chemical properties | Research | Analysis | Ligands (Biochemistry) | Cytochrome P-450
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 5/2007, Volume 24, Issue 5, pp. 909 - 917
To measure the solubility of four drugs in human gastric aspirates, canine gastric aspirates (CGF) and simulated gastric fluids in order to propose a medium... 
Biochemistry, general | felodipine | human gastric contents | miconazole | canine gastric contents | Biomedical Engineering | Biomedicine | dipyridamole | simulated gastric fluid | Pharmacy | Medical Law | ketoconazole | solubility | Pharmacology/Toxicology | Ketoconazole | Dipyridamole | Solubility | Canine gastric contents | Human gastric contents | Miconazole | Simulated gastric fluid | Felodipine | FLUIDS | PERFORMANCE | CHEMISTRY, MULTIDISCIPLINARY | DISSOLUTION BEHAVIOR | PLASMA | WEAK BASES | PHARMACOLOGY & PHARMACY | ABSORPTION | CANINE | FOOD | Stomach - chemistry | Dipyridamole - pharmacokinetics | Ketoconazole - administration & dosage | Humans | Felodipine - chemistry | Polyethylene Glycols - chemistry | Antifungal Agents - chemistry | Stomach - metabolism | Gastric Juice - chemistry | Solutions - chemistry | Osmolar Concentration | Time Factors | Antifungal Agents - pharmacokinetics | Felodipine - administration & dosage | Felodipine - pharmacokinetics | Water - administration & dosage | Adult | Female | Pharmaceutical Preparations - administration & dosage | Fasting | Miconazole - chemistry | Ketoconazole - pharmacokinetics | Ketoconazole - chemistry | Miconazole - administration & dosage | Pharmaceutical Preparations - metabolism | Animals | Miconazole - pharmacokinetics | Dipyridamole - chemistry | Dogs | Pharmaceutical Preparations - chemistry | Dipyridamole - administration & dosage | Kinetics | Antifungal Agents - administration & dosage | Hydrogen-Ion Concentration | Pharmacology | Bioavailability
Journal Article