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PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, p. e79977
We previously demonstrated that mitochondrial bioenergetic deficits in the female brain accompanied reproductive senescence and was accompanied by a shift from... 
MECHANISM | ASTROCYTE | MULTIDISCIPLINARY SCIENCES | LACTATE | DISEASE | HIPPOCAMPAL | ESTRADIOL | COGNITIVE IMPAIRMENT | ENERGY-METABOLISM | EXPRESSION | OLIGODENDROCYTES | Adaptation, Physiological | Ketone Oxidoreductases - metabolism | Neurons - pathology | Humans | Ketone Bodies - metabolism | Astrocytes - pathology | Glucose Transporter Type 1 - metabolism | Alzheimer Disease - pathology | Biological Transport, Active | Monocarboxylic Acid Transporters - metabolism | Aging - genetics | Female | Neurons - metabolism | Hexokinase - genetics | Disease Models, Animal | Gene Expression | Lactic Acid - metabolism | Mice, Transgenic | Hippocampus - pathology | Mitochondria - metabolism | Ketone Oxidoreductases - genetics | Aging - pathology | Blood-Brain Barrier - metabolism | Hippocampus - metabolism | Animals | Energy Metabolism | Glucose Transporter Type 1 - genetics | Alzheimer Disease - metabolism | Glucose - metabolism | Mice | Monocarboxylic Acid Transporters - genetics | Alzheimer Disease - genetics | Hexokinase - metabolism | Aging - metabolism | Astrocytes - metabolism | Lactates | Glucose metabolism | Enzymes | Brain | Neurons | Glucose | Alzheimer's disease | Dextrose | Neurosciences | Senescence | Adaptive systems | Dehydrogenases | Pyruvic acid | Ketone bodies | Fuels | Mitochondria | Bioenergetics | Blood-brain barrier | Rodents | Aging | Pharmaceutical sciences | Age | Glucose transporter | Phenotypes | Medical imaging | Neurodegenerative diseases | Ketones | Astrocytes | Pharmacology | Metabolism | Glucose transport | Fatty acids | Hexokinase | Utilization | Pharmacy | Glycolysis | Lactic acid | Laboratory animals | Transport | Alzheimers disease | Axonal transport | Transporter | Hippocampus | Animal cognition
Journal Article
Journal Article
Journal Article
Cell Cycle, ISSN 1538-4101, 05/2013, Volume 12, Issue 9, pp. 1371 - 1384
Here, we interrogated head and neck cancer (HNSCC) specimens (n = 12) to examine if different metabolic compartments (oxidative vs. glycolytic) co-exist in... 
stem cells | head and neck cancer | mitochondria | glycolysis | OXPHOS | TOMM20 | tumor recurrence | monocarboxylate transporters (MCT) | MCT4 | MCT1 | tumor stroma | metabolic symbiosis | oxidative stress | Oxidative stress | Tumor stroma | Monocarboxylate transporters (MCT) | Metabolic symbiosis | Mitochondria | Tumor recurrence | Stem cells | Glycolysis | Head and neck cancer | FDG-PET | MITOCHONDRIAL METABOLISM | CELL BIOLOGY | BREAST-CANCER | CYTOCHROME-C-OXIDASE | POSITRON-EMISSION-TOMOGRAPHY | PROGNOSTIC-FACTOR | AEROBIC GLYCOLYSIS | SQUAMOUS-CELL CARCINOMA | HYDROGEN-PEROXIDE | Cell Proliferation | Epithelial Cells - metabolism | Oxidative Stress | Humans | Ketone Bodies - metabolism | Middle Aged | Male | Head and Neck Neoplasms - metabolism | Neoplasm Recurrence, Local - pathology | Monocarboxylic Acid Transporters - metabolism | Neoplastic Stem Cells - metabolism | Muscle Proteins - metabolism | Aged, 80 and over | Biomarkers, Tumor - metabolism | Neoplastic Stem Cells - pathology | Female | Membrane Transport Proteins - metabolism | Cell Differentiation | Fibroblasts - metabolism | Neoplasm Recurrence, Local - metabolism | Lactic Acid - metabolism | Kaplan-Meier Estimate | Oxidative Phosphorylation | Receptors, Cell Surface - metabolism | Epithelial Cells - pathology | Mitochondria - metabolism | Fibroblasts - pathology | Symporters - metabolism | Head and Neck Neoplasms - pathology | Aged | Neoplasm Staging | Report
Journal Article
Forensic Science International, ISSN 0379-0738, 2012, Volume 226, Issue 1, pp. 54 - 61
Abstract The aim of this study was to investigate the usefulness of postmortem biochemical investigations in the diagnosis of fatal hypothermia. 10 cases of... 
Pathology | Ketone bodies | Postmortem biochemistry | Blood | Hypothermia | Biochemical markers | C-REACTIVE PROTEIN | MEDICINE, LEGAL | FATTY DEGENERATION | ACCIDENTAL HYPOTHERMIA | MEDICOLEGAL AUTOPSY | CREATINE-KINASE MB | CORTICOTROPIN-RELEASING FACTOR | POSTMORTEM CHEMISTRY UPDATE | PERICARDIAL FLUID | CARDIAC TROPONIN-I | ACUTE COLD STRESS | Calcium - metabolism | Humans | Middle Aged | Hydrocortisone - metabolism | Male | Pericardium - metabolism | Case-Control Studies | Young Adult | Fatty Acids, Nonesterified - metabolism | 2-Propanol - metabolism | C-Reactive Protein - metabolism | Human Growth Hormone - metabolism | Vitreous Body - metabolism | Hypothermia - metabolism | Hypothermia - mortality | Adult | Female | Forensic Pathology | Hypothermia - diagnosis | Calcitonin - metabolism | Adrenocorticotropic Hormone - metabolism | Biomarkers - metabolism | Calcitonin Gene-Related Peptide | Acetone - metabolism | Magnesium - metabolism | Thyrotropin - metabolism | Protein Precursors - metabolism | Glucose - metabolism | Aged | Hydroxybutyrates - metabolism | Ketones - metabolism | Postmortem Changes | Epinephrine - metabolism | Diagnosis | Biological markers | Analysis | Legal medicine | Fluid | Histology | Forensic pathology | Glucose | Nitrogen | Studies | Rodents | Pituitary gland | Fatalities | Growth hormones | Females | Age
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e59825
Previously, we demonstrated that reproductive senescence in female triple transgenic Alzheimer's (3xTgAD) mice was paralleled by a shift towards a ketogenic... 
POSITRON-EMISSION-TOMOGRAPHY | HORMONE-THERAPY | MULTIDISCIPLINARY SCIENCES | BRAIN GLUCOSE-METABOLISM | AEROBIC GLYCOLYSIS | IN-VIVO | A-BETA | HEXOKINASE-ACTIVITY | AMYLOID-BETA-PROTEIN | RAT-BRAIN | ENERGY-METABOLISM | L-Lactate Dehydrogenase - metabolism | Body Weight | Positron-Emission Tomography | X-Ray Microtomography | Isoenzymes - metabolism | Amyloid beta-Peptides - metabolism | Female | Neurons - metabolism | Estrogens - metabolism | Skin Temperature | Disease Models, Animal | Ovary - metabolism | Estradiol - metabolism | Ovariectomy | Gene Expression Regulation | Mice, Transgenic | Mitochondria - metabolism | Hippocampus - metabolism | Animals | Lactates - metabolism | Brain - pathology | Glucose - metabolism | Glycolysis | Mice | Alzheimer Disease - genetics | Brain | Glucose metabolism | Neurons | Physiological aspects | Genetic engineering | Genetic aspects | Glucose | Gene expression | Estradiol | Alzheimer's disease | Dextrose | Cytochrome | Neuroimaging | Energy metabolism | Neurosciences | Senescence | Estrogens | Ketone bodies | Hormones | Kinases | Proteins | Mitochondria | Energy resources | Bioenergetics | Rodents | Aging | Pharmaceutical sciences | Availability | Glucose transporter | Deprivation | Medical imaging | Preservation | Neurodegenerative diseases | Ketones | Transgenic mice | CoA transferase | Pharmacology | Fuel technology | Metabolism | Glucose transport | Substrates | Hexokinase | Neurology | Sex hormones | Pharmacy | Lactic acid | Respiration | Laboratory animals | Alzheimers disease | Transporter | Alternative fuels
Journal Article
Molecular Genetics and Metabolism, ISSN 1096-7192, 09/2016, Volume 119, Issue 1-2, pp. 57 - 67
Journal Article