Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (12525) 12525
Newsletter (52) 52
Book Chapter (35) 35
Magazine Article (22) 22
Book / eBook (6) 6
Dissertation (5) 5
Government Document (3) 3
Newspaper Article (2) 2
Publication (2) 2
Conference Proceeding (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (6420) 6420
science & technology (5847) 5847
life sciences & biomedicine (5472) 5472
humans (4244) 4244
biological and medical sciences (3036) 3036
male (3033) 3033
rats (2893) 2893
amino acid chloromethyl ketones - pharmacology (2482) 2482
ketones (2281) 2281
ketones - pharmacology (2114) 2114
medical sciences (1938) 1938
female (1821) 1821
mice (1717) 1717
biochemistry & molecular biology (1627) 1627
apoptosis (1543) 1543
pharmacology & pharmacy (1443) 1443
chemistry (1370) 1370
apoptosis - drug effects (1338) 1338
fundamental and applied biological sciences. psychology (1204) 1204
kinetics (1095) 1095
cysteine proteinase inhibitors - pharmacology (1074) 1074
ketones - chemistry (1071) 1071
pharmacology. drug treatments (1052) 1052
caspase inhibitors (1014) 1014
liver - metabolism (936) 936
caspases - metabolism (918) 918
cell biology (906) 906
cells, cultured (828) 828
physical sciences (820) 820
time factors (786) 786
dose-response relationship, drug (783) 783
structure-activity relationship (773) 773
in vitro techniques (740) 740
chemistry, medicinal (713) 713
cell line (679) 679
enzyme inhibitors - pharmacology (674) 674
cell line, tumor (648) 648
ketones - chemical synthesis (634) 634
liver - drug effects (627) 627
abridged index medicus (624) 624
oxidation-reduction (615) 615
research (608) 608
ketone bodies - metabolism (607) 607
oncology (605) 605
rats, inbred strains (593) 593
analysis (581) 581
ketone bodies - blood (577) 577
proteins (548) 548
toxicology (543) 543
adult (538) 538
old medline (519) 519
molecular structure (513) 513
apoptosis - physiology (478) 478
neurosciences & neurology (468) 468
caspase 3 (467) 467
antineoplastic agents - pharmacology (465) 465
ketones - metabolism (456) 456
research article (455) 455
neurosciences (435) 435
ketone bodies - biosynthesis (430) 430
organic compounds (428) 428
tosylphenylalanyl chloromethyl ketone - pharmacology (426) 426
cell survival - drug effects (421) 421
chemical phenomena (401) 401
ketone oxidoreductases - metabolism (396) 396
enzyme activation (388) 388
oligopeptides - pharmacology (388) 388
tumor cells, cultured (387) 387
rats, sprague-dawley (384) 384
metabolism (382) 382
enzymes (373) 373
middle aged (366) 366
binding sites (359) 359
physiological aspects (359) 359
rabbits (359) 359
glucose - metabolism (357) 357
ketone bodies (354) 354
tosyllysine chloromethyl ketone - pharmacology (354) 354
rodents (351) 351
chemistry, organic (347) 347
mitochondria - metabolism (344) 344
pharmacology (341) 341
stereoisomerism (340) 340
fatty acids, nonesterified - blood (339) 339
steroids (337) 337
hydrogen-ion concentration (336) 336
organic chemistry (332) 332
cancer (324) 324
immunology (324) 324
enzyme activation - drug effects (322) 322
blood glucose - metabolism (317) 317
caspase (311) 311
molecular sequence data (310) 310
rats, wistar (309) 309
magnetic resonance spectroscopy (306) 306
amino acid sequence (304) 304
cattle (303) 303
liver - enzymology (300) 300
antineoplastic agents (295) 295
hydroxy compounds (295) 295
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (11734) 11734
Japanese (453) 453
German (442) 442
French (109) 109
Russian (92) 92
Italian (82) 82
Chinese (41) 41
Polish (31) 31
Spanish (15) 15
Ukrainian (11) 11
Czech (9) 9
Portuguese (8) 8
Dutch (4) 4
Hungarian (3) 3
Danish (2) 2
Norwegian (2) 2
Bulgarian (1) 1
Latvian (1) 1
Romanian (1) 1
Serbian (1) 1
Slovak (1) 1
Slovenian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Recent Advances in the Development of Antineoplastic Agents Derived from Natural Products
by Trendowski, Matthew
Drugs (New York, N.Y.), ISSN 0012-6667, 11/2015, Volume 75, Issue 17, pp. 1993 - 2016
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Dioxoles - therapeutic use | Diphtheria Toxin - pharmacology | Recombinant Fusion Proteins - pharmacology | Furans - pharmacology | Humans | Recombinant Fusion Proteins - therapeutic use | Interleukin-2 - therapeutic use | Epothilones - pharmacology | Drug Discovery - methods | Antineoplastic Agents - therapeutic use | Biological Products - pharmacology | Epothilones - therapeutic use | Harringtonines - therapeutic use | Furans - therapeutic use | TOR Serine-Threonine Kinases - antagonists & inhibitors | Diphtheria Toxin - therapeutic use | Immunoconjugates - pharmacology | Cytochalasins - pharmacology | Dioxoles - pharmacology | Immunoconjugates - therapeutic use | Antineoplastic Agents - pharmacology | Ketones - therapeutic use | Cytochalasins - therapeutic use | Biological Products - therapeutic use | Ketones - pharmacology | Tetrahydroisoquinolines - pharmacology | Tetrahydroisoquinolines - therapeutic use | Withanolides - pharmacology | Harringtonines - pharmacology | Interleukin-2 - pharmacology | Withanolides - therapeutic use | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Exploring pharmacological significance of chalcone scaffold: A review
by Sahu, N.K and Balbhadra, S.S and Choudhary, J and Kohli, D.V
Current medicinal chemistry, ISSN 0929-8673, 01/2012, Volume 19, Issue 2, pp. 209 - 225
α,β-unsaturated ketone | Antimalarial | Xanthohumol | Anticancer activity | Licochalcone | Chalcone | Butein | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Antioxidants - chemistry | Anti-Inflammatory Agents - pharmacology | Anti-Infective Agents - pharmacology | Enzyme Inhibitors - pharmacology | Hypoglycemic Agents - chemistry | Antioxidants - pharmacology | Antineoplastic Agents - chemistry | Hypoglycemic Agents - pharmacology | Anti-Inflammatory Agents - chemistry | Chalcone - pharmacology | Chalcone - analogs & derivatives | Anti-Infective Agents - chemistry | Enzyme Inhibitors - chemistry | Antineoplastic Agents - pharmacology
Journal Article
Details down arrow
3. Full Text Zinc pyrithione inhibits caspase-3 activity, promotes ErbB1-ErbB2 heterodimerization and suppresses ErbB2 downregulation in cardiomyocytes subjected to ischemia/reperfusion
by Bodiga, Vijaya Lakshmi and Thokala, Sandhya and Vemuri, Praveen Kumar and Bodiga, Sreedhar
Journal of inorganic biochemistry, ISSN 0162-0134, 12/2015, Volume 153, pp. 49 - 59
Hypoxia | Reoxygenation | Proteolysis | Caspase-3 | Zinc | Apoptosis | Biochemistry & Molecular Biology | Physical Sciences | Chemistry, Inorganic & Nuclear | Chemistry | Life Sciences & Biomedicine | Science & Technology | Receptor, Epidermal Growth Factor - genetics | Caspase Inhibitors - pharmacology | Phosphorylation | Receptor, ErbB-2 - genetics | Protein Multimerization | Caspase 3 - metabolism | Receptor, ErbB-2 - metabolism | RNA, Messenger - metabolism | Cell Hypoxia | Receptor, Epidermal Growth Factor - metabolism | Zinc Compounds - pharmacology | Amino Acid Chloromethyl Ketones - pharmacology | Receptor, ErbB-2 - antagonists & inhibitors | Proteasome Inhibitors - pharmacology | Benzothiazoles - pharmacology | Chlorides - pharmacology | Down-Regulation | RNA, Messenger - genetics | Rats | Tyrphostins - pharmacology | Cardiotonic Agents - pharmacology | Leupeptins - pharmacology | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Thiones - pharmacology | Quinazolines - pharmacology | Organometallic Compounds - pharmacology | Proteins | Membrane lipids | Inositol | RNA | Antifungal agents | Permeability | Antibacterial agents | Phosphotransferases | Tyrosine | Cell death | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells
by Chen, Y and McMillan-Ward, E and Kong, J and Israels, S.J and Gibson, S.B
Cell death and differentiation, ISSN 1350-9047, 01/2008, Volume 15, Issue 1, pp. 171 - 182
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Astrocytes - cytology | Astrocytes - drug effects | Estradiol - analogs & derivatives | Oxidants - pharmacology | Adenine - analogs & derivatives | Reactive Oxygen Species - metabolism | Oxidative Stress | Tubulin Modulators - pharmacology | Humans | RNA, Small Interfering - pharmacology | Hydrogen Peroxide - pharmacology | Adenine - pharmacology | Autophagy | Animals | Amino Acid Chloromethyl Ketones - pharmacology | Cysteine Proteinase Inhibitors - pharmacology | Cell Line, Tumor | Mice | HeLa Cells | Cell Line, Transformed | Estradiol - pharmacology | Apoptosis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text An early and robust activation of caspases heads cells for a regulated form of necrotic-like cell death
by Garcia-Belinchón, Mercè and Sánchez-Osuna, María and Martínez-Escardó, Laura and Granados-Colomina, Carla and Pascual-Guiral, Sònia and Iglesias-Guimarais, Victoria and Casanelles, Elisenda and Ribas, Judit and Yuste, Victor J
The Journal of biological chemistry, ISSN 0021-9258, 08/2015, Volume 290, Issue 34, pp. 20841 - 20855
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Chromatin - metabolism | Colchicine - pharmacology | Apoptosis - drug effects | Humans | Nocodazole - pharmacology | Apoptosis - genetics | Quinolines - pharmacology | Caspases - metabolism | Amino Acid Chloromethyl Ketones - pharmacology | Rotenone - pharmacology | Antineoplastic Agents - pharmacology | Microfilament Proteins - metabolism | Chromatin - drug effects | Microfilament Proteins - genetics | Chromatin - ultrastructure | Peptidomimetics - pharmacology | Signal Transduction | Caspases - genetics | Neurons | Antibodies, Monoclonal - pharmacology | Enzyme Inhibitors - pharmacology | Gene Expression Regulation | Enzyme Activation - drug effects | Benzophenanthridines - pharmacology | Necrosis - chemically induced | Carrier Proteins - genetics | Carrier Proteins - metabolism | Cell Line, Tumor | Thapsigargin - pharmacology | Necrosis - genetics | Necrosis - enzymology | Staurosporine - pharmacology | Index Medicus | DNA and Chromosomes | apoptotic nuclear morphology | cell death | thiolic oxidative stress | chelerythrine | apoptosis | necrosis (necrotic death) | oxidative stress | caspase
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Anticancer Drugs from Traditional Toxic Chinese Medicines
by Man, Shuli and Gao, Wenyuan and Wei, Changlong and Liu, Changxiao
Phytotherapy research, ISSN 0951-418X, 10/2012, Volume 26, Issue 10, pp. 1449 - 1465
traditional toxic Chinese medicine | mechanism | toxic effects | arsenic trioxide | anticancer | phytochemistry | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | Pharmacognosy. Homeopathy. Health food | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Ketones - pharmacology | Plants, Medicinal - chemistry | Alkaloids - pharmacology | Medicine, Chinese Traditional | Humans | Drugs, Chinese Herbal - pharmacology | Lignans - pharmacology | Neoplasms - drug therapy | Terpenes - pharmacology | Drugs, Chinese Herbal - toxicity | Animals | Steroids - pharmacology | Phytotherapy | Antineoplastic Agents, Phytogenic - pharmacology | Antimitotic agents | Care and treatment | Antineoplastic agents | Cancer | Arsenic compounds | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation
by Puissant, Alexandre and Robert, Guillaume and Fenouille, Nina and Luciano, Frederic and Cassuto, Jill-Patrice and Raynaud, Sophie and Auberger, Patrick
Cancer research (Chicago, Ill.), ISSN 0008-5472, 02/2010, Volume 70, Issue 3, pp. 1042 - 1052
Life Sciences & Biomedicine | Oncology | Science & Technology | Hematologic and hematopoietic diseases | Pharmacology. Drug treatments | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Antineoplastic agents | Tumors | AMP-Activated Protein Kinases - metabolism | Sequestosome-1 Protein | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | Drug Resistance, Neoplasm | JNK Mitogen-Activated Protein Kinases - metabolism | Stilbenes - pharmacology | Vacuolar Proton-Translocating ATPases - metabolism | Autophagy - drug effects | Caspases - metabolism | RNA Interference | Amino Acid Chloromethyl Ketones - pharmacology | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Macrolides - pharmacology | Antineoplastic Agents - pharmacology | JNK Mitogen-Activated Protein Kinases - genetics | Tumor Cells, Cultured | Cell Survival - drug effects | Pyrimidines - pharmacology | Microscopy, Electron | Caspase Inhibitors | Imatinib Mesylate | Piperazines - pharmacology | Blotting, Western | Microscopy, Confocal | Vacuolar Proton-Translocating ATPases - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - genetics | K562 Cells | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Benzamides | Adaptor Proteins, Signal Transducing - metabolism | Antineoplastic Agents, Phytogenic - pharmacology | AMP-Activated Protein Kinases - genetics | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights