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2, chemokine ligand 1 (1) 1
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keywords sinusoidal obstruction syndrome oxaliplatin colorectal liver metastases chemotherapy induced liver injury (1) 1
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sinusoidal obstruction syndrome (1) 1
sos, sinusoidal obstruction syndrome (1) 1
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Journal of Hepatology, ISSN 0168-8278, 2013, Volume 59, Issue 2, pp. 318 - 326
Background & Aims Sinusoidal obstruction syndrome (SOS) following oxaliplatin based chemotherapy can have a significant impact on post-operative outcome... 
Gastroenterology and Hepatology | Sinusoidal obstruction syndrome | Oxaliplatin | Colorectal liver metastases | Chemotherapy induced liver injury | Keywords Sinusoidal obstruction syndrome Oxaliplatin Colorectal liver metastases Chemotherapy induced liver injury | FIBROSIS | VENOOCCLUSIVE DISEASE | CANCER | P53 | NEOADJUVANT CHEMOTHERAPY | ANIMAL-MODEL | SENESCENCE | STEATOHEPATITIS | OXALIPLATIN-BASED CHEMOTHERAPY | GASTROENTEROLOGY & HEPATOLOGY | Thrombosis - chemically induced | Oxidative Stress | Humans | Fluorouracil - toxicity | Liver Cirrhosis - chemically induced | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Colorectal Neoplasms - drug therapy | Inflammation Mediators - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Hepatic Veno-Occlusive Disease - pathology | Liver Neoplasms - secondary | Cytokines - genetics | Disease Models, Animal | Cytokines - metabolism | Mice, Inbred C57BL | Liver Neoplasms - drug therapy | Hepatic Veno-Occlusive Disease - metabolism | Liver Neoplasms - surgery | Neovascularization, Pathologic - chemically induced | Antineoplastic Combined Chemotherapy Protocols - toxicity | Hepatic Veno-Occlusive Disease - chemically induced | Organoplatinum Compounds - toxicity | Serpin E2 - genetics | Animals | Cell Cycle | Antioxidants - administration & dosage | Leucovorin - toxicity | Mice | Serpin E2 - metabolism | Chemotherapy | Analysis | Cancer | MCP1, monocyte chemotactic protein-1 | CRLM, colorectal liver metastases | NRF2, nuclear factor (erythroid-derived 2)-like 2 | HPF, high powered field | PAI-1, plasminogen activatior inhibitor 1 | ALP, alkaline phosphatase | CXCL1 | IL-6, interleukin 6 | NAC, N-acetylcysteine | PCNA, proliferating cell nuclear antigen | C, vascular endothelial growth factor A | PAR 1 | TXN1, thioredoxin 1 | 2, protease activated receptor 1 | 2, vascular endothelial growth factor receptor | NQO1, NAD(P)H dehydrogenase 1 | ALT, alanine aminotransferase | BHA, butylated hydroxyanisole | SOS, sinusoidal obstruction syndrome | STAT3, signal transducer and activator of transcription 3 | H&E, haematoxylin and eosin | VEGF-A | vWF, von Willebrand factor | 2, chemokine (C-X-C motif) ligand 1 | GAPDH, gyceraldehyde 3-phosphate dehydrogenase | γH2AX, phosphorylated form of the H2A histone family, member X | i.p., intraperitoneal | VEGFR-1 | AST, aspartate aminotransferase
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