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Journal of Clinical Investigation, ISSN 0021-9738, 09/2017, Volume 127, Issue 9, pp. 3462 - 3471
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 05/2017, Volume 16, Issue 5, pp. 879 - 892
Antibody-drug conjugates (ADC) are highly potent and specific antitumor drugs, combining the specific targeting of mAbs with the potency of small-molecule... 
BREAST-CANCER | TRASTUZUMAB | EFFICACY | ONCOLOGY | RANDOMIZED PHASE-II | STABILITY | DOXORUBICIN | CELL LINES | RESISTANCE | CYTOTOXIC DRUG | ANTITUMOR-ACTIVITY | Cysteine Endopeptidases - chemistry | Humans | Bacterial Proteins - chemistry | Ki-1 Antigen - immunology | Doxorubicin - chemistry | Immunoconjugates - administration & dosage | Immunoconjugates - immunology | Anthracyclines - administration & dosage | Doxorubicin - analogs & derivatives | Maytansine - chemistry | Receptor, ErbB-2 - antagonists & inhibitors | Receptor, ErbB-2 - immunology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Doxorubicin - administration & dosage | Ki-1 Antigen - chemistry | Trastuzumab - chemistry | Aminoacyltransferases - chemistry | Anthracyclines - chemistry | Maytansine - analogs & derivatives | Trastuzumab - administration & dosage | Immunoconjugates - chemistry | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | Antibodies, Monoclonal - administration & dosage | Neoplasms - immunology | Cell Line, Tumor | Mice | Trastuzumab - immunology | Maytansine - immunology | Drugs | Conjugates | Pharmacology | Drug delivery | ErbB-2 protein | DIABLO protein | CD30 antigen | Tubulin | Anthracycline | Biocompatibility | Conjugation | Pharmacokinetics | Trastuzumab | Sortase | Payloads | Cancer | Index Medicus
Journal Article
PLoS Pathogens, ISSN 1553-7366, 02/2018, Volume 14, Issue 2, p. e1006856
HIV-1-infected cells persist indefinitely despite the use of combination antiretroviral therapy (ART), and novel therapeutic strategies to target and purge... 
ACTIVATION | MOLECULE | IFN-GAMMA | PERSISTENCE | BRENTUXIMAB VEDOTIN | POSITIVE PATIENTS | MICROBIOLOGY | ANTIRETROVIRAL THERAPY | HIGH SERUM-LEVEL | SOLUBLE CD30 | VIROLOGY | PLASMA-LEVELS | PARASITOLOGY | Anti-HIV Agents - pharmacology | HIV-1 - pathogenicity | Rectum - pathology | Humans | Transcriptional Activation - drug effects | RNA, Viral - blood | CD4-Positive T-Lymphocytes - pathology | Rectum - virology | Immunoconjugates - pharmacology | HIV-1 - physiology | In Situ Hybridization | Ki-1 Antigen - blood | Rectum - drug effects | HIV Infections - pathology | HIV-1 - isolation & purification | RNA, Viral - metabolism | CD4-Positive T-Lymphocytes - virology | Lymphoid Tissue - drug effects | Ki-1 Antigen - chemistry | Biomarkers - metabolism | HIV-1 - drug effects | Lymphoid Tissue - virology | HIV Infections - virology | Rectum - metabolism | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | DNA, Viral - metabolism | Solubility | Lymphoid Tissue - metabolism | CD4 Lymphocyte Count | Biomarkers - blood | Ki-1 Antigen - metabolism | Antiretroviral Therapy, Highly Active | DNA, Viral - blood | Lymphoid Tissue - pathology | Ki-1 Antigen - antagonists & inhibitors | HIV Infections - drug therapy | Viral Load - drug effects | CD4-Positive T-Lymphocytes - drug effects | Cohort Studies | HIV Infections - metabolism | Transcription | Viruses | Leukocytes (mononuclear) | Lymphocytes T | Hybridization | Tissues | Blood | Immunology | CD30 antigen | Lymphocytes | Antiretroviral agents | Gut-associated lymphoid tissues | Human immunodeficiency virus--HIV | Peripheral blood mononuclear cells | Localization | Drug therapy | Supervision | Deoxyribonucleic acid--DNA | Therapeutic applications | Lymphoid tissue | Gene expression | Ribonucleic acid--RNA | Lymphoma | Antiretroviral therapy | CD4 antigen | Virology | Medicine | RNA | Deoxyribonucleic acid | Ribonucleic acid | HIV | DNA | Human immunodeficiency virus
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, p. e45244
The TNF-receptor superfamily member CD30 is expressed on normal and malignant lymphocytes, including anaplastic large cell lymphoma (ALCL) cells. CD30... 
PROTEIN TRADD | MULTIDISCIPLINARY SCIENCES | IN-VIVO | KINASE | CYCLE ARREST | RECEPTOR SUPERFAMILY | IKK-ALPHA | LARGE-CELL LYMPHOMA | BINDING-SITES | TNF | T-CELLS | Apoptosis - drug effects | Humans | Molecular Sequence Data | NF-kappa B - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | I-kappa B Kinase - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Transcription, Genetic | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Nuclear Proteins - genetics | Lymphoma, Large-Cell, Anaplastic - metabolism | Ki-1 Antigen - chemistry | Lymphoma, Large-Cell, Anaplastic - genetics | Lymphocytes - metabolism | Protein Structure, Tertiary | Recombinant Proteins - chemistry | Nuclear Proteins - metabolism | Recombinant Proteins - genetics | I-kappa B Kinase - genetics | Recombinant Proteins - pharmacology | Amino Acid Motifs | Lymphocytes - pathology | NF-kappa B - genetics | Signal Transduction - drug effects | Cell Cycle Checkpoints - drug effects | Lymphocytes - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Lymphoma, Large-Cell, Anaplastic - pathology | Ki-1 Antigen - pharmacology | Ki-1 Antigen - genetics | Cell proliferation | Phosphorylation | Transcription factors | Activation | Kinases | Proteins | Cyclin-dependent kinase | Signal transduction | Biological effects | Cell activation | Cell growth | CD30 antigen | Lymphocytes | Transcription activation | Cell cycle | Tumor necrosis factor-TNF | Translocation | NF-κB protein | Lymphoma | Nuclear transport | Signaling | Cyclin-dependent kinase inhibitor p21 | Tumor necrosis factor | Plasmids | Ligands | Lymphomas | Anaplastic large-cell lymphoma | Intracellular | Cancer | Apoptosis
Journal Article
Journal Article
Transplantation, ISSN 0041-1337, 10/2003, Volume 76, Issue 8, pp. 1231 - 1232
The influence of human leukocyte antigen (HILA) matching on graft survival is greater in patients with preformed lymphocytotoxic antibodies than in... 
SURGERY | IMMUNOLOGY | TRANSPLANTATION | Immunization | Ki-1 Antigen - blood | Histocompatibility Testing | Humans | Solubility | Graft Survival | Kidney Transplantation | Histocompatibility | Cadaver | Preoperative Care | Ki-1 Antigen - chemistry
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 01/2004, Volume 113, Issue 2, pp. 310 - 317
Journal Article
Expert review of hematology, 01/2017, Volume 10, Issue 1, p. 29
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2009, Volume 4, Issue 4, p. e5175
Background: Ectromelia virus (ECTV) is the causative agent of mousepox, a lethal disease of mice with similarities to human smallpox. Mousepox progression... 
TNF RECEPTOR | TUMOR-NECROSIS-FACTOR | CD30 HOMOLOG | COWPOX VIRUSES | BACTERIAL ARTIFICIAL CHROMOSOME | MULTIDISCIPLINARY SCIENCES | INTERFERON-BINDING PROTEIN | VACCINIA VIRUS | POXVIRUS INFECTION | FACTOR RECEPTOR | T-CELLS | Cell Line | Ectromelia virus - genetics | Viral Proteins - chemistry | Humans | Protein Multimerization | Viral Proteins - immunology | Viral Proteins - genetics | Ki-1 Antigen - immunology | Disease Progression | Animals | Ectromelia virus - immunology | Ectromelia virus - pathogenicity | Ectromelia, Infectious - immunology | Virus Replication | Recombination, Genetic | Female | Ligands | Mice | Mice, Inbred BALB C | Mutation | Ki-1 Antigen - chemistry | Ki-1 Antigen - genetics | Proteins | Analysis | Liver | Genomics | Nucleotide sequencing | Health aspects | Methods | DNA sequencing | Disease | Pathogenesis | Exanthema | Homology | Viruses | Lymphocytes T | Genomes | Infections | Gene sequencing | Deletion mutant | CD30 antigen | Clonal deletion | Lymphocytes | Deletion | Tumor necrosis factor-TNF | Trends | Deoxyribonucleic acid--DNA | Recombinant | Immune system | Spleen | Smallpox | Pathogens | Immune response | Cytokines | Nucleotide sequence | Immunomodulation | Organs | Mutants | Tumor necrosis factor | In vivo methods and tests | Skin | Recombinants | Viral infections | Tumors | Deoxyribonucleic acid | DNA
Journal Article