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Clinical Cancer Research, ISSN 1078-0432, 03/2017, Volume 23, Issue 5, pp. 1156 - 1166
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, pp. e0131177 - e0131177
Antibody drug conjugates (ADCs) have recently been proven to be highly potent anti-tumor drugs, typically exceeding the efficacy of conventional monoclonal... 
RECOMBINANT IMMUNOTOXIN | IMMUNOGENICITY | MULTIDISCIPLINARY SCIENCES | PURIFICATION | SURFACE-PROTEINS | STAPHYLOCOCCUS-AUREUS | ANTITUMOR-ACTIVITY | MONOCLONAL-ANTIBODIES | FRAGMENTATION | CANCER-THERAPY | PROTEIN LIGATION | Cysteine Endopeptidases - chemistry | Staphylococcus aureus - enzymology | Aminoacyltransferases - immunology | Receptor, ErbB-2 - genetics | Humans | Bacterial Proteins - chemistry | Ovarian Neoplasms - pathology | Ki-1 Antigen - immunology | Maytansine - pharmacology | Immunoconjugates - immunology | Immunoconjugates - pharmacology | Antibodies, Monoclonal, Humanized - pharmacology | Protein Engineering | Maytansine - chemistry | Female | Antineoplastic Agents - pharmacology | Bacterial Proteins - immunology | Receptor, ErbB-2 - antagonists & inhibitors | Receptor, ErbB-2 - immunology | Oligopeptides - chemistry | Ovarian Neoplasms - drug therapy | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Aminoacyltransferases - chemistry | Antineoplastic Agents - immunology | Maytansine - analogs & derivatives | Antibodies, Monoclonal - pharmacology | Oligopeptides - immunology | Antineoplastic Agents - chemistry | Immunoconjugates - chemistry | Staphylococcus aureus - chemistry | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Ki-1 Antigen - antagonists & inhibitors | Mice | Antibodies, Monoclonal, Humanized - immunology | Cysteine Endopeptidases - immunology | Maytansine - immunology | Trastuzumab | Antibodies, Monoclonal, Humanized - chemistry | Ki-1 Antigen - genetics | Ovarian Neoplasms - immunology | Monoclonal antibodies | Enzymes | Cysteine | Peptides | Biopharmaceutics | Drugs | Conjugates | Addition polymerization | Ovarian carcinoma | Clinical trials | Pentaglycine | Cancer therapies | Molecular weight | Ovarian cancer | Proteins | Tubulin | CD30 antigen | Xenografts | Medical research | Immunoglobulins | Polypeptides | Cloning | Polymerization | Breast cancer | ErbB-2 protein | Substrates | Chemotherapy | Lysine | Heavy chains | Toxins | Conjugation | Sortase | Tumors | Cancer | Index Medicus
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 05/2017, Volume 16, Issue 5, pp. 879 - 892
Antibody-drug conjugates (ADC) are highly potent and specific antitumor drugs, combining the specific targeting of mAbs with the potency of small-molecule... 
BREAST-CANCER | TRASTUZUMAB | EFFICACY | ONCOLOGY | RANDOMIZED PHASE-II | STABILITY | DOXORUBICIN | CELL LINES | RESISTANCE | CYTOTOXIC DRUG | ANTITUMOR-ACTIVITY | Cysteine Endopeptidases - chemistry | Humans | Bacterial Proteins - chemistry | Ki-1 Antigen - immunology | Doxorubicin - chemistry | Immunoconjugates - administration & dosage | Immunoconjugates - immunology | Anthracyclines - administration & dosage | Doxorubicin - analogs & derivatives | Maytansine - chemistry | Receptor, ErbB-2 - antagonists & inhibitors | Receptor, ErbB-2 - immunology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Doxorubicin - administration & dosage | Ki-1 Antigen - chemistry | Trastuzumab - chemistry | Aminoacyltransferases - chemistry | Anthracyclines - chemistry | Maytansine - analogs & derivatives | Trastuzumab - administration & dosage | Immunoconjugates - chemistry | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | Antibodies, Monoclonal - administration & dosage | Neoplasms - immunology | Cell Line, Tumor | Mice | Trastuzumab - immunology | Maytansine - immunology | Drugs | Conjugates | Pharmacology | Drug delivery | ErbB-2 protein | DIABLO protein | CD30 antigen | Tubulin | Anthracycline | Biocompatibility | Conjugation | Pharmacokinetics | Trastuzumab | Sortase | Payloads | Cancer | Index Medicus
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2013, Volume 31, Issue 5, pp. e59 - e63
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2011, Volume 17, Issue 20, pp. 6428 - 6436
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 08/2006, Volume 6, Issue 8, pp. 1865 - 1874
Journal Article
Journal of Immunology, ISSN 0022-1767, 2010, Volume 185, Issue 4, pp. 2071 - 2079
Journal Article
Cancer Epidemiology Biomarkers and Prevention, ISSN 1055-9965, 07/2017, Volume 26, Issue 7, pp. 1114 - 1123
Background: We investigated whether an immune system environment characterized by elevated serum levels of B-cell activation molecules was associated with the... 
REED-STERNBERG CELLS | CENTER B-CELLS | SOLUBLE CD30 | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | INTERLEUKIN-6 EXPRESSION | ONCOLOGY | IMMUNOGLOBULIN-E LEVELS | POOR-PROGNOSIS | IN-SITU HYBRIDIZATION | TUMOR-CELLS | EPSTEIN-BARR-VIRUS | CLINICAL-SIGNIFICANCE | Hodgkin Disease - virology | Prospective Studies | United States | Humans | Interleukin-10 - blood | Ki-1 Antigen - immunology | Male | Case-Control Studies | Immunoglobulin E - blood | Young Adult | Herpesvirus 4, Human - isolation & purification | Ki-1 Antigen - blood | Interleukin-6 - blood | Adult | Female | Epstein-Barr Virus Infections - blood | B-Lymphocytes - metabolism | Epstein-Barr Virus Infections - virology | Carcinogenesis - immunology | Epstein-Barr Virus Infections - immunology | Risk Factors | Hodgkin Disease - diagnosis | Military Personnel - statistics & numerical data | B-Lymphocytes - immunology | Hodgkin Disease - blood | Interleukin-6 - immunology | Epstein-Barr Virus Infections - diagnosis | Hodgkin Disease - immunology | United States Department of Defense | Interleukin-10 - immunology | Cytokines | Tumor cells | Immunoglobulin E | Viruses | Risk | Lymphoma | Interleukin 6 | Immune systems | Serum levels | Confidence intervals | Cell activation | CD30 antigen | Lymphocytes B | Interleukin 10 | Interleukin 1 | Biomarkers | Measurement methods | Lymphomas | Bioindicators | Diagnosis | Hodgkin's disease | Cancer | Immune system | Index Medicus
Journal Article
17.