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Journal of Biological Chemistry, ISSN 0021-9258, 07/2011, Volume 286, Issue 29, pp. 25586 - 25603
Hyperglycemia induces a wide array of signaling pathways in the kidney that lead to hypertrophy and matrix expansion, eventually culminating in progressive... 
MAMMALIAN TARGET | FIBRONECTIN EXPRESSION | MESSENGER-RNA TRANSLATION | GROWTH-FACTOR-BETA | EPITHELIAL-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDUCED COLLAGEN EXPRESSION | MESANGIAL CELLS | SUPEROXIDE-DISMUTASE | PROTEIN-SYNTHESIS | TRANSGENIC MICE | Hypertrophy - chemically induced | Kidney Cortex - drug effects | Epithelial Cells - metabolism | Kidney - pathology | Kidney Cortex - metabolism | Epithelial Cells - drug effects | Humans | Diabetes Mellitus, Type 1 - metabolism | Hypertrophy - metabolism | Mesangial Cells - drug effects | Dose-Response Relationship, Drug | Kidney - metabolism | Base Sequence | Hypertrophy - genetics | Regulatory-Associated Protein of mTOR | PTEN Phosphohydrolase - genetics | Diabetic Nephropathies - pathology | Kidney Tubules, Proximal - pathology | Kidney - drug effects | Diabetic Nephropathies - metabolism | Diabetes Mellitus, Type 1 - pathology | Diabetes Mellitus, Type 1 - genetics | Rats | Diabetic Nephropathies - genetics | Epithelial Cells - pathology | Kidney Cortex - pathology | Glucose - pharmacology | Mesangial Cells - metabolism | Down-Regulation - drug effects | Animals | Signal Transduction - drug effects | Mesangial Cells - pathology | Fibronectins - genetics | Mice | MicroRNAs - genetics | Adaptor Proteins, Signal Transducing - metabolism | Kidney Tubules, Proximal - drug effects | Index Medicus | mTOR | Molecular Bases of Disease | Diabetes | Akt PKB | Fibronectin | Kidney
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 2016, Volume 85, pp. 323 - 333
Abstract We compared the relative protective abilities of silymarin and l -methionine pre-treatment in acetaminophen overdose injuries of the liver, kidney and... 
Internal Medicine | Medical Education | Oxidative stress | Drug overdose | Silymarin | l-Methionine | Antioxidant | L-Methionine | MEDICINE, RESEARCH & EXPERIMENTAL | PARACETAMOL | BRAIN-DAMAGE | ADULT MICE | DIPHENYL DISELENIDE | RECEPTOR ACTIVATION | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | RAT-BRAIN | OPEN-FIELD | INDUCED HEPATOTOXICITY | Brain Diseases - metabolism | Liver - pathology | Kidney - pathology | Rats, Wistar | Cerebral Cortex - pathology | Motor Activity - drug effects | Methionine - pharmacology | Anxiety - prevention & control | Cerebral Cortex - metabolism | Brain Diseases - chemically induced | Dose-Response Relationship, Drug | Kidney - metabolism | Liver - drug effects | Time Factors | Kidney Diseases - chemically induced | Behavior, Animal - drug effects | Weight Gain - drug effects | Silymarin - pharmacology | Cerebral Cortex - drug effects | Chemical and Drug Induced Liver Injury - pathology | Anxiety - metabolism | Cytoprotection | Disease Models, Animal | Kidney Diseases - metabolism | Biomarkers - metabolism | Chemical and Drug Induced Liver Injury - prevention & control | Kidney - drug effects | Kidney Diseases - pathology | Kidney Diseases - prevention & control | Liver - metabolism | Grooming - drug effects | Memory, Short-Term - drug effects | Antioxidants - pharmacology | Organ Specificity | Animals | Brain Diseases - pathology | Brain Diseases - prevention & control | Spatial Memory - drug effects | Acetaminophen | Chemical and Drug Induced Liver Injury - metabolism | Anxiety - chemically induced | Oxidative Stress - drug effects | Antioxidants | Drugs | Brain | Amino acids | Overdose | Comparative analysis | Index Medicus
Journal Article
Journal Article
Journal Article
Life Sciences, ISSN 0024-3205, 01/2017, Volume 169, pp. 43 - 51
Adriamycin (ADR)-induced nephropathy is one of the most experimental models used in progressive kidney disease. A single dose of this drug induces a... 
Angiogenesis | Previous physical training | Renal disease progression | Adriamycin toxicity | Endothelial lesions | MEDICINE, RESEARCH & EXPERIMENTAL | ALBUMINURIA | NITRIC-OXIDE SYNTHASE | RATS | INJURY | LACTATE-STEADY-STATE | PHARMACOLOGY & PHARMACY | AEROBIC EXERCISE | GROWTH-FACTOR | KIDNEY | EXPRESSION | PROGRESSION | Kidney Cortex - drug effects | Kidney - blood supply | Kidney - pathology | Rats, Wistar | Nitric Oxide Synthase Type III - analysis | Male | Kidney Diseases - urine | Doxorubicin | Kidney Diseases - chemically induced | Albuminuria - urine | Albuminuria - pathology | Interleukin-1beta - analysis | Kidney - drug effects | Kidney Cortex - blood supply | Kidney Diseases - pathology | Kidney Diseases - prevention & control | Kidney Cortex - pathology | Vascular Endothelial Growth Factor A - analysis | Podocytes - pathology | Animals | Podocytes - drug effects | Chemokine CCL2 - urine | Albuminuria - chemically induced | Creatinine - blood | Running | Anthracyclines | Kidney diseases | Analysis | Endothelium | Medical research | Exercise | Endothelial growth factors | Nitric oxide | Medicine, Experimental | Development and progression | Drugs | Intervention | Physical training | Physical activity | Syngeneic grafts | Interleukin | Macrophages | Reduction | Lesions | Vascular endothelial growth factor | Enzyme-linked immunosorbent assay | Enlargement | Urine | Creatinine | Damage assessment | Kidneys | Rats | Inflammation | IL-1β | Nitric-oxide synthase | Physical fitness | Nephropathy | Monocyte chemoattractant protein | Renal cortex | Proteinuria | Index Medicus
Journal Article
Journal Article
Kidney International, ISSN 0085-2538, 03/2012, Volume 81, Issue 6, pp. 513 - 515
Journal Article
Journal Article
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 04/2016, Volume 43, Issue 4, pp. 484 - 493
Cardiovascular ( CV ) representation has been identified within the insular cortex ( IC ) and a lateralization of function previously suggested. In order to... 
metil | NMDA | autonomic nervous system | insular cortex | aspartate | cardiovascular control | Cardiovascular control | Autonomic nervous system | Insular cortex | N-metil-D-aspartate (NMDA) | ARRHYTHMIAS | BARORECEPTOR-RELATED NEURONS | PHYSIOLOGY | STIMULATION | REPRESENTATION | LATERALIZATION | ROSTRAL VENTROLATERAL MEDULLA | AUTONOMIC RESPONSES | PHARMACOLOGY & PHARMACY | HYPERTENSIVE-RATS | ISCHEMIC-STROKE | HYPOTHALAMUS | Receptors, Glutamate - metabolism | Rats, Wistar | Tachycardia - chemically induced | Adrenergic beta-1 Receptor Antagonists - pharmacology | Receptors, N-Methyl-D-Aspartate - metabolism | Male | Autonomic Nervous System - physiopathology | Cerebral Cortex - metabolism | Cerebral Cortex - physiopathology | N-Methylaspartate - pharmacology | Receptors, N-Methyl-D-Aspartate - genetics | Heart Rate - drug effects | Adrenergic alpha-1 Receptor Antagonists - pharmacology | Muscarinic Antagonists - pharmacology | Arterial Pressure - drug effects | Cardiovascular Physiological Phenomena - drug effects | Cerebral Cortex - drug effects | Autonomic Nervous System - drug effects | Autonomic Nervous System - physiology | Bradycardia - physiopathology | Rats | Tachycardia - physiopathology | Gene Expression Regulation - drug effects | Bradycardia - chemically induced | Animals | Cerebral Cortex - physiology | Kidney - innervation | Laws, regulations and rules | Aspartate | Index Medicus
Journal Article
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