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Journal Article
Kidney International, ISSN 0085-2538, 12/2013, Volume 84, Issue 6, pp. 1079 - 1089
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2011, Volume 187, Issue 1, pp. 172 - 180
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 08/2017, Volume 69, Issue 8, pp. 1636 - 1646
Objective. Development of proteinuria in lupus nephritis (LN) is associated with podocyte dysfunction. The NLRP3 inflammasome has been implicated in the... 
CRESCENTIC GLOMERULONEPHRITIS | CELLS | INTERLEUKIN-1 RECEPTOR ANTAGONIST | MAJOR SOURCE | INJURY | MECHANISMS | MICE | RHEUMATOLOGY | KIDNEY | DAMAGE | ERYTHEMATOSUS | Interleukin-1beta - drug effects | Reactive Oxygen Species - metabolism | Humans | Kidney - immunology | Caspase 1 - metabolism | Caspase 1 - immunology | Proteinuria - pathology | Sulfones - pharmacology | Heterocyclic Compounds, 4 or More Rings - pharmacology | Kidney Glomerulus - ultrastructure | Kidney - metabolism | Flow Cytometry | Interleukin-1beta - metabolism | Kidney Glomerulus - metabolism | Lupus Nephritis - metabolism | Lupus Nephritis - pathology | Cell Line | Microscopy, Electron, Transmission | Kidney - drug effects | Inflammasomes | Proteinuria - immunology | Kidney Glomerulus - drug effects | NLR Family, Pyrin Domain-Containing 3 Protein - antagonists & inhibitors | Interleukin-1beta - immunology | Proteinuria - metabolism | Lupus Nephritis - immunology | Blotting, Western | Kidney - ultrastructure | Microscopy, Confocal | Podocytes - ultrastructure | Animals | NLR Family, Pyrin Domain-Containing 3 Protein - immunology | Podocytes - drug effects | Caspase 1 - drug effects | Podocytes - immunology | Mice | Kidney Glomerulus - immunology | Flow cytometry | Reactive oxygen species | Nephritis | Pathogenesis | Fluorescence | Activation | Lupus nephritis | Tissues | Caspase-1 | Ultrastructure | Rodents | Lesions | Activation analysis | Lupus | Kidneys | Caspase | Patients | Feet | Cytometry | Inhibitors | Biopsy | Autoimmune diseases | In vitro methods and tests | Proteinuria | Kidney transplantation | Index Medicus | Abridged Index Medicus | lupus nephritis | NLRP3 inflammasome | IL-1β | podocytes
Journal Article
Kidney International, ISSN 0085-2538, 08/2012, Volume 82, Issue 4, pp. 454 - 464
Dense deposit disease and glomerulonephritis with isolated C3 deposits are glomerulopathies characterized by deposits of C3 within or along the glomerular... 
complement | glomerulonephritis | clinical immunology | membranoproliferative glomerulonephritis (MPGN) | LONG-TERM | HEMOLYTIC-UREMIC SYNDROME | MESANGIOCAPILLARY GLOMERULONEPHRITIS | GLOMERULONEPHRITIS TYPE-II | MACULAR DEGENERATION | FACTOR-H DEFICIENCY | GLOMERULAR-FILTRATION-RATE | UROLOGY & NEPHROLOGY | MUTATIONS | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | MEMBRANE COFACTOR PROTEIN | Humans | Child, Preschool | Male | Complement System Proteins - metabolism | Young Adult | Time Factors | DNA Mutational Analysis | Renal Insufficiency - immunology | Child | Glomerulonephritis, Membranoproliferative - pathology | Genetic Predisposition to Disease | Risk Assessment | Complement C3 - metabolism | Gene Frequency | Risk Factors | Glomerulonephritis - genetics | Glomerulonephritis - immunology | Glomerulonephritis - mortality | Biomarkers - blood | Kidney Glomerulus - pathology | Disease Progression | Glomerulonephritis, Membranoproliferative - genetics | Glomerulonephritis, Membranoproliferative - immunology | Phenotype | Complement Factor H - metabolism | Glomerulonephritis, Membranoproliferative - mortality | Glomerulonephritis - pathology | Adolescent | Age of Onset | Membrane Cofactor Protein - genetics | Kidney Glomerulus - immunology | Mutation | Complement Factor I - metabolism | Haplotypes | Complement C3 Nephritic Factor - genetics | Glomerulonephritis - therapy | Infant | Case-Control Studies | Adult | Complement System Proteins - genetics | Female | Membrane Cofactor Protein - metabolism | Complement Pathway, Alternative - genetics | France | Renal Insufficiency - genetics | Kaplan-Meier Estimate | Complement Factor I - genetics | Treatment Outcome | Chi-Square Distribution | Glomerulonephritis, Membranoproliferative - therapy | Biopsy | Complement C3 Nephritic Factor - metabolism | Complement Factor H - genetics | Index Medicus
Journal Article
Kidney International, ISSN 0085-2538, 08/2012, Volume 82, Issue 4, pp. 465 - 473
C3 glomerulonephritis (C3GN) is a recently described disorder that typically results from abnormalities in the alternative pathway (AP) of complement. Here, we... 
C3GN | proteomics | C3 glomerulopathy | MPGN | alternative pathway of complement | C3 glomerulonephritis | MACULAR DEGENERATION | CLASSIFICATION | RISK | PROTEIN 5 | DENSE DEPOSIT DISEASE | ALTERNATIVE PATHWAY | UROLOGY & NEPHROLOGY | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | Complement C3 - analysis | Predictive Value of Tests | Recurrence | Follow-Up Studies | Humans | Middle Aged | Complement System Proteins - immunology | Laser Capture Microdissection | Molecular Sequence Data | Male | Glomerulonephritis, Membranoproliferative - complications | Complement System Proteins - analysis | Young Adult | Time Factors | DNA Mutational Analysis | Mass Spectrometry | Adult | Autoantibodies - analysis | Complement System Proteins - genetics | Female | Complement Pathway, Alternative - genetics | Proteomics - methods | Child | Amino Acid Sequence | Glomerulonephritis, Membranoproliferative - pathology | Genetic Predisposition to Disease | Proteinuria - immunology | Treatment Outcome | Complement C3 Nephritic Factor - analysis | Hematuria - immunology | Kidney Transplantation | Minnesota | Kidney Glomerulus - pathology | Glomerulonephritis, Membranoproliferative - therapy | Glomerulonephritis, Membranoproliferative - genetics | Glomerulonephritis, Membranoproliferative - immunology | Biopsy | Adolescent | Aged | Kidney Glomerulus - immunology | Mutation | Complement Factor H - genetics | Index Medicus
Journal Article
Journal Article
Kidney International, ISSN 0085-2538, 2014, Volume 85, Issue 2, pp. 333 - 343
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2014, Volume 57, pp. 42 - 52
Abstract Kidney involvement affects 40–60% of patients with lupus, and is responsible for significant morbidity and mortality. Using depletion approaches,... 
Allergy and Immunology | Lupus nephritis | Macrophages | SLE | Nephrotoxic serum nephritis (NTS) | SYSTEMIC-LUPUS-ERYTHEMATOSUS | RENAL MACROPHAGES | COLONY-STIMULATING FACTOR | FACTOR-I | IMMUNOLOGY | ANTI-DNA ANTIBODY | NEPHROTOXIC SERUM NEPHRITIS | MRL/LPR MICE | DISEASE | MURINE LUPUS | TWEAK/FN14 PATHWAY | Pyrimidines - immunology | Gene Expression - drug effects | Glomerulonephritis - prevention & control | Anisoles - pharmacology | Humans | Kidney - immunology | Matrix Metalloproteinase 9 - immunology | HMGB1 Protein - immunology | Anisoles - immunology | HMGB1 Protein - genetics | Proteinuria - prevention & control | Kidney - metabolism | Matrix Metalloproteinase 9 - metabolism | Flow Cytometry | T-Lymphocytes - metabolism | Immunoglobulin G - immunology | Matrix Metalloproteinase 9 - genetics | HMGB1 Protein - metabolism | Gene Expression - immunology | Antibodies - immunology | Kidney Glomerulus - metabolism | Mice, Inbred DBA | Macrophages - immunology | Disease Models, Animal | Rabbits | Kidney - drug effects | Proteinuria - immunology | Mice, Inbred C57BL | Glomerulonephritis - immunology | Lupus Nephritis - immunology | Kidney Glomerulus - pathology | Pyrimidines - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Macrophages - metabolism | Animals | Macrophages - drug effects | T-Lymphocytes - immunology | Kidney Glomerulus - immunology | Immunoglobulin G - metabolism | Lupus Nephritis - prevention & control | Lupus | Autoimmunity | Nephritis | Autoantibodies | Analysis | Mortality | Gene expression | Index Medicus | lupus nephritis | nephrotoxic serum nephritis (NTS)
Journal Article