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Journal of Clinical Oncology, ISSN 0732-183X, 12/2017, Volume 35, Issue 35, pp. 3916 - 3923
Journal Article
Cancer Research, ISSN 0008-5472, 08/2011, Volume 71, Issue 15, pp. 5346 - 5356
Journal Article
Cancer Journal (United States), ISSN 1528-9117, 07/2015, Volume 21, Issue 4, pp. 274 - 283
The clinical circumstance of treating spontaneous metastatic disease, after resection of primary tumors, whether advanced/overt or microscopic in nature, is... 
antiangiogenic drugs | metronomic low-dose chemotherapy | spontaneous metastatic disease | experimental therapeutic investigations | 1ST-LINE TREATMENT | ANTITUMOR-ACTIVITY | PLUS PACLITAXEL | MOUSE MODELS | PHASE-III TRIAL | BREAST-CANCER | THERAPY | ONCOLOGY | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | DOUBLE-BLIND | ORAL TOPOTECAN | Neoplasm Transplantation | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Melanoma - blood supply | Administration, Metronomic | Humans | Ovarian Neoplasms - pathology | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Angiogenesis Inhibitors - administration & dosage | Neoplasm Metastasis - drug therapy | Colorectal Neoplasms - drug therapy | Angiogenesis Inhibitors - therapeutic use | Female | Ovarian Neoplasms - blood supply | Drug Evaluation, Preclinical | Ovarian Neoplasms - drug therapy | Disease Models, Animal | Tumor Microenvironment - drug effects | Colorectal Neoplasms - blood supply | Neoplasms - blood supply | Breast Neoplasms - blood supply | Melanoma - pathology | Breast Neoplasms - drug therapy | Neoplasms - drug therapy | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Neovascularization, Pathologic - drug therapy | Melanoma - drug therapy | Cell Line, Tumor | Kidney Neoplasms - pathology | Mice | Colorectal Neoplasms - pathology | Kidney Neoplasms - drug therapy | Kidney Neoplasms - blood supply
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2008, Volume 105, Issue 27, pp. 9343 - 9348
Integrin ανβ3 is found on a subset of tumor blood vessels where it is associated with angiogenesis and malignant tumor growth. We designed an ανβ3-targeted... 
Cardiovascular system | Angiogenesis | Microscopy | Renal cell carcinoma | Antineoplastics | Blood vessels | Metastasis | Tumors | Integrins | Cancer | Intravital microscopy | Liposome | Antiangiogenic | Pancreatic cancer | REGRESSION | intravital microscopy | ANGIOGENESIS | RGD PEPTIDES | antiangiogenic | MULTIDISCIPLINARY SCIENCES | PANCREATIC-CANCER | DOXORUBICIN | ORTHOTOPIC MODEL | liposome | BREAST-CANCER | pancreatic cancer | renal cell carcinoma | ALPHA-V-BETA-3 | VX-2 RABBIT TUMORS | INTEGRIN ALPHA(V)BETA ANTAGONISTS | Endothelium - pathology | Doxorubicin - therapeutic use | Carcinoma, Renal Cell - pathology | Pancreatic Neoplasms - blood supply | Pancreatic Neoplasms - pathology | Angiogenesis Inhibitors - pharmacology | Neoplasms - blood supply | Integrin alphaVbeta3 - metabolism | Drug Delivery Systems | Neovascularization, Pathologic - pathology | Nanoparticles | Xenograft Model Antitumor Assays | Endothelium - drug effects | Animals | Neoplasm Metastasis - drug therapy | Cell Line, Tumor | Kidney Neoplasms - pathology | Mice | Neoplasms - pathology | Oligopeptides - pharmacology | Doxorubicin - pharmacology | Disease Models, Animal | Doxorubicin - administration & dosage | Control | Blood-vessels | Physiological aspects | Genetic aspects | Carcinoma, Renal cell | Research | Neovascularization | Risk factors | Methods | Biological Sciences
Journal Article
Nature Communications, ISSN 2041-1723, 04/2016, Volume 7, Issue 1, p. 11169
Journal Article
Cancer Research, ISSN 0008-5472, 08/2008, Volume 68, Issue 16, pp. 6822 - 6830
Herein, using transgenic adenocarcinoma of the mouse prostate (TRAMP) model, we assessed the "stage-specific" efficacy of silibinin feeding against prostate... 
EPITHELIAL-MESENCHYMAL TRANSITION | MATRIX | POTENTIAL TARGET | TRAMP MODEL | ANGIOGENESIS | ONCOLOGY | MICE | AGENTS | CANCER CHEMOPREVENTION | ENDOTHELIAL GROWTH-FACTOR | Humans | Body Weight - drug effects | Male | Vascular Endothelial Growth Factor A - metabolism | Kidney Neoplasms - prevention & control | Biomarkers, Tumor | Immunoenzyme Techniques | Lung Neoplasms - secondary | Prostate - drug effects | Prostatic Intraepithelial Neoplasia - blood supply | Female | Neovascularization, Pathologic - prevention & control | Prostatic Neoplasms - prevention & control | Tumor Cells, Cultured | Liver Neoplasms - secondary | Disease Models, Animal | Lung Neoplasms - blood supply | Liver Neoplasms - prevention & control | Prostatic Neoplasms - blood supply | Prostatic Neoplasms - pathology | Silymarin - therapeutic use | Mice, Inbred C57BL | Cell Cycle Proteins - metabolism | Mice, Transgenic | Adenocarcinoma - secondary | Blotting, Western | Disease Progression | Adenocarcinoma - blood supply | Xenograft Model Antitumor Assays | Antioxidants - therapeutic use | Milk Thistle | Adenocarcinoma - prevention & control | Animals | Liver Neoplasms - blood supply | Lung Neoplasms - prevention & control | Mice, Nude | Prostatic Intraepithelial Neoplasia - secondary | Prostatic Intraepithelial Neoplasia - prevention & control | Cell Proliferation - drug effects | Mice | Kidney Neoplasms - secondary | Neoplasm Staging | Kidney Neoplasms - blood supply | Apoptosis | Cell Movement | Nitric Oxide Synthase Type II - metabolism
Journal Article
Cancer Research, ISSN 0008-5472, 11/2011, Volume 71, Issue 21, pp. 6601 - 6610
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 07/2013, Volume 73, Issue 14, pp. 4579 - 4590
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 2010, Volume 9, Issue 6, pp. 1525 - 1535
Tyrosine kinase inhibitors (TKI) targeting angiogenesis via inhibition of the vascular endothelial growth factor pathway have changed the medical management of... 
ACTIVATION | ANGIOGENESIS | ONCOLOGY | IN-VIVO | TYROSINE KINASE INHIBITOR | HUMAN CANCERS | ANTITUMOR-ACTIVITY | HYPOXIA | SU11248 | ENDOTHELIAL GROWTH-FACTOR | Kidney Neoplasms - genetics | Pericytes - drug effects | Humans | Mesoderm - drug effects | Carcinoma, Renal Cell - genetics | Angiogenesis Inhibitors - blood | Pericytes - pathology | Angiogenesis Inhibitors - therapeutic use | Indoles - pharmacology | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Gene Expression Regulation, Neoplastic - drug effects | Carcinoma, Renal Cell - drug therapy | Pyrroles - therapeutic use | Carcinoma, Renal Cell - blood supply | Epithelium - drug effects | Epithelium - pathology | Carcinoma, Renal Cell - pathology | Indoles - blood | Angiogenesis Inhibitors - pharmacology | Microvessels - drug effects | Pyrroles - blood | Disease Progression | Xenograft Model Antitumor Assays | Phenotype | Pyrroles - pharmacology | Animals | Mice, Nude | Protein Kinase Inhibitors - therapeutic use | Skin Neoplasms - secondary | Cell Line, Tumor | Indoles - therapeutic use | Kidney Neoplasms - pathology | Mice | Protein Kinase Inhibitors - pharmacology | Kidney Neoplasms - drug therapy | Mesoderm - pathology | Kidney Neoplasms - blood supply | Drug Resistance, Neoplasm - drug effects | renal cell carcinoma | angiogenesis inhibitors | Vascular endothelial growth factor | resistance
Journal Article