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Kidney International, ISSN 0085-2538, 02/2012, Volume 81, Issue 4, pp. 338 - 340
Oxidant stress and compromised microcirculation underlie renal pathophysiology in septic acute kidney injury (AKI). Holthoff report that resveratrol... 
RAT-KIDNEY | INFLAMMATION | DISEASE | NITRIC-OXIDE | ENDOTOXEMIA | UROLOGY & NEPHROLOGY | ACUTE-RENAL-FAILURE | MICE | SEPSIS | DYSFUNCTION | Antioxidants - therapeutic use | Animals | Stilbenes - therapeutic use | Acute Kidney Injury - drug therapy | Male | Sepsis - blood | Microcirculation - drug effects | Kidney - physiopathology | Index Medicus
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 12/2013, Volume 273, Issue 2, pp. 345 - 354
Kidney ischemia–reperfusion (I/R) injury elicits cellular injury in the proximal tubule, and mitochondrial dysfunction is a pathological consequence of I/R.... 
SRT1720 | Proximal tubule | Mitochondrial biogenesis | Mitochondrial dysfunction | Ischemia–reperfusion | Acute kidney injury | Ischemia-reperfusion | PGC-1-ALPHA | EPITHELIAL POLARITY | SIRT1 | ENERGY-EXPENDITURE | OXIDANT INJURY | PHARMACOLOGY & PHARMACY | TOXICOLOGY | PROMOTES RECOVERY | HISTONE DEACETYLASE | SMALL-MOLECULE ACTIVATORS | CALORIE RESTRICTION | Kidney - pathology | Recovery of Function - drug effects | Reperfusion Injury - drug therapy | Male | Heterocyclic Compounds, 4 or More Rings - pharmacology | Kidney - metabolism | Heterocyclic Compounds, 4 or More Rings - therapeutic use | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Recovery of Function - physiology | Homeostasis - drug effects | Kidney Tubules - pathology | Kidney Tubules - metabolism | Reperfusion Injury - metabolism | Kidney - drug effects | Kidney Tubules - drug effects | Reperfusion Injury - pathology | Sirtuin 1 - biosynthesis | Rats | Transcription Factors - biosynthesis | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Rats, Sprague-Dawley | Animals | Homeostasis - physiology | Index Medicus | HOMEOSTASIS | INJURIES | EPITHELIUM | MITOCHONDRIA | CREATININE | RATS | RECEPTORS | 60 APPLIED LIFE SCIENCES | ATP | POTASSIUM IONS | SODIUM IONS | mitochondrial dysfunction | acute kidney injury | ischemia-reperfusion | proximal tubule | mitochondrial biogenesis
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 12/2014, Volume 21, Issue 1, pp. 37 - 46
Journal Article
Kidney International, ISSN 0085-2538, 09/2012, Volume 82, Issue 5, pp. 537 - 547
β-Catenin is a unique intracellular protein functioning as an integral component of the cell–cell adherens complex and a principal signaling protein mediating... 
β-catenin | apoptosis | acute kidney injury | Wnt | beta-catenin | INTEGRIN-LINKED KINASE | PROAPOPTOTIC BAX | GAMMA-CATENIN | MECHANISMS | PODOCYTE INJURY | EPITHELIAL-CELLS | UROLOGY & NEPHROLOGY | AMELIORATES PROTEINURIA | UP-REGULATION | RENAL INTERSTITIAL FIBROSIS | Reperfusion Injury - etiology | Wnt1 Protein - genetics | Phosphorylation | Epithelial Cells - metabolism | Cadherins - metabolism | Inhibitor of Apoptosis Proteins - genetics | Humans | Acute Kidney Injury - genetics | Wnt1 Protein - metabolism | Adherens Junctions - metabolism | Transfection | Time Factors | Acute Kidney Injury - chemically induced | Inhibitor of Apoptosis Proteins - metabolism | Kidney Tubules - pathology | Kidney Tubules - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Reperfusion Injury - genetics | Reperfusion Injury - metabolism | Repressor Proteins - metabolism | Disease Models, Animal | Folic Acid | Cell Line | Reperfusion Injury - pathology | Acute Kidney Injury - pathology | Mice, Inbred C57BL | beta Catenin - deficiency | Tumor Suppressor Protein p53 - metabolism | bcl-2-Associated X Protein - metabolism | gamma Catenin - metabolism | Repressor Proteins - genetics | Genotype | Survivin | beta Catenin - metabolism | beta Catenin - genetics | Mice, Knockout | Phenotype | Animals | Creatinine - blood | Mice | Acute Kidney Injury - metabolism | Apoptosis | Index Medicus
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 07/2003, Volume 112, Issue 1, pp. 42 - 49
  The paradigm for recovery of the renal tubule from acute tubular necrosis is that surviving cells from the areas bordering the injury must migrate into the... 
Index Medicus | Abridged Index Medicus
Journal Article
Kidney International, ISSN 0085-2538, 08/2012, Volume 82, Issue 4, pp. 412 - 427
Endothelial progenitor cells are known to reverse acute kidney injury by paracrine mechanisms. We previously found that microvesicles released from these... 
exosome | ischemia–reperfusion | acute kidney injury | ischemia-reperfusion | HORIZONTAL TRANSFER | STEM-CELLS | CONTRIBUTE | REGENERATION | FAILURE | EXPERIMENTAL GLOMERULONEPHRITIS | REPAIR | EPITHELIAL-CELLS | MESSENGER-RNA | UROLOGY & NEPHROLOGY | PLATELET-ACTIVATING-FACTOR | Chemotaxis, Leukocyte | Cell Proliferation | Epithelial Cells - metabolism | Kidney - blood supply | Capillaries - pathology | Kidney - pathology | Rats, Wistar | Endothelial Cells - transplantation | Cell-Derived Microparticles - transplantation | Male | MicroRNAs - metabolism | Acute Kidney Injury - genetics | Stem Cells - metabolism | Cell Hypoxia | Stem Cell Transplantation | Kidney - metabolism | Transfection | RNA Interference | Time Factors | Cell-Derived Microparticles - pathology | Cell-Derived Microparticles - metabolism | Kidney Tubules - pathology | Kidney Tubules - metabolism | Capillaries - metabolism | Reperfusion Injury - genetics | Reperfusion Injury - metabolism | Disease Models, Animal | Ribonuclease III - genetics | Ribonuclease III - metabolism | Reperfusion Injury - pathology | Acute Kidney Injury - pathology | Endothelial Cells - metabolism | Cells, Cultured | Gene Expression Regulation | Rats | Epithelial Cells - pathology | Acute Kidney Injury - prevention & control | Regeneration | Oligonucleotides - metabolism | Animals | Reperfusion Injury - prevention & control | Fibrosis | Stem Cells - pathology | Acute Kidney Injury - metabolism | Endothelial Cells - pathology | Apoptosis | Index Medicus | Cell proliferation | Intravenous administration | Paracrine signalling | mRNA | Leukocytes | Ribonuclease | Endothelial cells | Kidney | Angiogenesis | Ischemia | Stem cells | Hypoxia | miRNA | Capillaries | Injuries
Journal Article