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Gastroenterology, ISSN 0016-5085, 2010, Volume 139, Issue 3, pp. 882 - 892.e3
Journal Article
Nature Immunology, ISSN 1529-2908, 05/2010, Volume 11, Issue 5, pp. 395 - 402
Inflammasomes regulate the activity of caspase-1 and the maturation of interleukin 1. (IL-1.) and IL-18. AIM2 has been shown to bind DNA and engage the... 
RECOGNITION | TOLL-LIKE RECEPTOR | INDUCIBLE GENES | INNATE IMMUNE-RESPONSE | INFECTION | VACCINIA VIRUS | IMMUNOLOGY | MURINE CYTOMEGALOVIRUS | FRANCISELLA-TULARENSIS | CASPASE-1 ACTIVATION | FAMILY | Tularemia - metabolism | Cytoskeletal Proteins - genetics | Humans | Tularemia - genetics | Caspase 1 - metabolism | Multiprotein Complexes - genetics | Multiprotein Complexes - metabolism | Lymphocyte Activation - genetics | Transcription Factors - immunology | Cytokines - genetics | Macrophages - microbiology | DNA-Binding Proteins | DNA Viruses - pathogenicity | Macrophages - pathology | Killer Cells, Natural - virology | Listeriosis - genetics | Signal Transduction - genetics | DNA Virus Infections - genetics | Viral Load - immunology | Mice, Knockout | Macrophages - metabolism | DNA Virus Infections - immunology | Mice | Killer Cells, Natural - metabolism | Multiprotein Complexes - immunology | DNA Virus Infections - metabolism | Caspase 1 - immunology | Killer Cells, Natural - pathology | Signal Transduction - immunology | Macrophages - virology | Listeriosis - immunology | Tularemia - immunology | Killer Cells, Natural - immunology | Nuclear Proteins - genetics | Macrophages - immunology | Cytokines - immunology | Killer Cells, Natural - microbiology | Cell Line | Francisella tularensis - immunology | Listeriosis - metabolism | Cytokines - metabolism | DNA - immunology | Mice, Inbred C57BL | Nuclear Proteins - metabolism | Transcription Factors - genetics | Immunity, Innate | Nuclear Proteins - immunology | Viral Load - genetics | DNA Viruses - immunology | Transcription Factors - metabolism | Animals | Apoptosis Regulatory Proteins | Caspase 1 - genetics | DNA Viruses - growth & development | CARD Signaling Adaptor Proteins | Francisella tularensis - pathogenicity | Bacterial infections | Immune response | Cytomegalovirus infections | Research | DNA viruses | Health aspects | Risk factors | Index Medicus
Journal Article
PLoS Pathogens, ISSN 1553-7366, 11/2010, Volume 6, Issue 11, pp. e1001191 - e1001191
Pneumolysin (PLY) is a key Streptococcus pneumoniae virulence factor and potential candidate for inclusion in pneumococcal subunit vaccines. Dendritic cells... 
HUMAN NEUTROPHILS | DENDRITIC CELLS | PNEUMOCOCCAL INFECTION | MICROBIOLOGY | NALP3 INFLAMMASOME | TOLL-LIKE RECEPTOR-4 | VIROLOGY | IL-17-PRODUCING T-CELLS | HOST-DEFENSE | PORE-FORMING TOXINS | STREPTOCOCCUS-PNEUMONIAE INFECTION | CASPASE-1 ACTIVATION | PARASITOLOGY | Lung - microbiology | Pneumococcal Infections - metabolism | Bone Marrow - immunology | Spleen - immunology | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Spleen - microbiology | Streptococcus pneumoniae - immunology | Pneumococcal Infections - immunology | Flow Cytometry | Streptococcus pneumoniae - pathogenicity | Bone Marrow - metabolism | Inflammation Mediators - metabolism | Killer Cells, Natural - immunology | Female | Pneumococcal Infections - microbiology | Lung - metabolism | Dendritic Cells - metabolism | Killer Cells, Natural - microbiology | Enzyme-Linked Immunosorbent Assay | Lymphocyte Activation | Streptolysins - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Cytokines - secretion | Toll-Like Receptor 4 - metabolism | Mice, Inbred C3H | Bacterial Proteins - pharmacology | Animals | Carrier Proteins - metabolism | Spleen - metabolism | Dendritic Cells - microbiology | Mice | Mice, Inbred BALB C | Killer Cells, Natural - metabolism | Bone Marrow - microbiology | Lung - immunology | Adoptive transfer | Index Medicus | Pneumonia | Vaccines | Cytokines | Kinases | Immune system
Journal Article
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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2013, Volume 110, Issue 6, pp. 2252 - 2257
IFN-γ is critical for immunity against infections with intracellular pathogens, such as Salmonella enterica. However, which of the many cell types capable of... 
T lymphocytes | Salmonella | Salmonella infections | Lymphocytes | B lymphocytes | Antibodies | Infections | Mice | Natural killer cells | Immunity | Intracellular bacteria | Cytokines | Infection immunity | Vaccination | LISTERIA-MONOCYTOGENES | NATURAL-KILLER-CELLS | ENTERICA SEROVAR TYPHIMURIUM | INITIAL SUPPRESSION | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | infection immunity | VIRULENT SALMONELLAE | intracellular bacteria | ADAPTIVE IMMUNITY | ADOPTIVE TRANSFER | cytokines | ORAL CHALLENGE | T-CELLS | vaccination | Homeodomain Proteins - immunology | Killer Cells, Natural - pathology | Adoptive Transfer | DNA-Binding Proteins - deficiency | Lymphocyte Subsets - immunology | Salmonella Infections, Animal - immunology | Killer Cells, Natural - immunology | Interferon-gamma - genetics | Interferon-gamma - deficiency | Lymphocyte Subsets - pathology | Killer Cells, Natural - microbiology | DNA-Binding Proteins - immunology | Salmonella typhimurium - genetics | Salmonella typhimurium - immunology | Mice, Inbred C57BL | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Killer Cells, Natural - classification | Mice, Knockout | Thy-1 Antigens - metabolism | Cell Differentiation - immunology | Animals | Lymphocyte Subsets - microbiology | Salmonella Infections, Animal - microbiology | Interferon-gamma - biosynthesis | Index Medicus | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2018, Volume 115, Issue 45, pp. 11585 - 11590
The cytokine IFN-gamma is a critical regulator of immune system development and function. Almost all leukocytes express the receptor for IFN-gamma(,) yet each... 
Cell biology | Cytokines | T cell differentiation | Integrins | LISTERIA-MONOCYTOGENES | NAIVE CELLS | ACTIVATION | MULTIDISCIPLINARY SCIENCES | RECEPTOR | MECHANISMS | EFFECTOR | integrins | cell biology | INTERFERON-GAMMA | MEMORY | AUTOCRINE | cytokines | INFECTION | Spleen - immunology | Tetradecanoylphorbol Acetate - pharmacology | Listeria monocytogenes - immunology | Paracrine Communication - immunology | Killer Cells, Natural - immunology | Killer Cells, Natural - microbiology | CD8-Positive T-Lymphocytes - microbiology | Signal Transduction | Integrins - immunology | Mice, Inbred C57BL | Cellular Microenvironment | Listeria monocytogenes - growth & development | Spleen - cytology | Lymph Nodes - immunology | Lymph Nodes - cytology | Cell Differentiation - immunology | Immunological Synapses | Animals | Cell Differentiation - drug effects | Lymphocyte Activation - drug effects | CD8-Positive T-Lymphocytes - drug effects | Interferon-gamma - immunology | Immunologic Memory | Killer Cells, Natural - drug effects | Mice | Primary Cell Culture | CD8-Positive T-Lymphocytes - immunology | Interferon-gamma - pharmacology | Phosphorylation | CD8 antigen | Differentiation (biology) | Paracrine signalling | Immunological synapses | Lymphocytes T | Infections | Leukocytes | Cell interactions | Cofactors | Interleukin 2 | Lymphocytes | Down-regulation | Natural killer cells | Stat1 protein | Immune system | Spleen | Interleukin 2 receptors | Immunological memory | Secretion | Cell differentiation | Cells | White blood cells | Immune systems | Cellular biology | γ-Interferon | Synapses | Index Medicus | Biological Sciences
Journal Article
Immunity, ISSN 1074-7613, 07/2016, Volume 45, Issue 1, pp. 131 - 144
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