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The American Journal of Human Genetics, ISSN 0002-9297, 2011, Volume 88, Issue 3, pp. 306 - 316
Journal Article
Nature Communications, ISSN 2041-1723, 11/2015, Volume 6, Issue 1, pp. 8804 - 8804
textabstractEczema often precedes the development of asthma in a disease course called the a 'atopic march'. To unravel the genes underlying this... 
CHROMOSOME 11Q13 | JUVENILE MYOCLONIC EPILEPSY | DERMATITIS | FOOD ALLERGY | GENOMEWIDE ASSOCIATION | MULTIDISCIPLINARY SCIENCES | RISK | FILAGGRIN MUTATIONS | BIRTH COHORT | HAY-FEVER | CHILDHOOD ASTHMA | Phenotypes | Interleukin 4 | Eczema | Chromosome 6 | Skin diseases | Chromosome 12 | Allergic diseases | Genomes | Children | Loci | Asthma | Atopy | Index Medicus
Journal Article
PLoS Genetics, ISSN 1553-7390, 04/2011, Volume 7, Issue 4, pp. e1001363 - e1001363
Journal Article
by Paternoster, Lavinia and Standl, Marie and Chen, Chih-Mei and Ramasamy, Adaikalavan and Bonnelykke, Klaus and Duijts, Liesbeth and Ferreira, Manuel A and Alves, Alexessander Couto and Thyssen, Jacob P and Albrecht, Eva and Baurecht, Hansjoerg and Feenstra, Bjarke and Sleiman, Patrick M. A and Hysi, Pirro and Warrington, Nicole M and Curjuric, Ivan and Myhre, Ronny and Curtin, John A and Groen-Blokhuis, Maria M and Kerkhof, Marjan and Saaf, Annika and Franke, Ane and Ellinghaus, David and Foelster-Holst, Regina and Dermitzakis, Emmanouil and Montgomery, Stephen B and Prokisch, Holger and Heim, Katharina and Hartikainen, Anna-Liisa and Pouta, Anneli and Pekkanen, Juha and Blakemore, Alexana I. F and Buxton, Jessica L and Kaakinen, Marika and Duffy, David L and Madden, Pamela A and Heath, Anew C and Montgomery, Grant W and Thompson, Philip J and Matheson, Melanie C and Le Souef, Peter and St Pourcain, Beate and Smith, George Davey and Henderson, John and Kemp, John P and Timpson, Nicholas J and Deloukas, Panos and Ring, Susan M and Wichmann, H-Erich and Mueller-Nurasyid, Martina and Novak, Natalija and Klopp, Norman and Roiguez, Elke and McArdle, Wendy and Linneberg, Allan and Menne, Torkil and Nohr, Ellen A and Hofman, Albert and Uitterlinden, Ane G and van Duijin, Cornelia M and Rivadeneira, Fernando and de Jongste, Johan C and van der Valk, Ralf J. P and Wjst, Matthias and Jogi, Rain and Geller, Frank and Boyd, Heather A and Murray, Jeffrey C and Kim, Cecilia and Mentch, Frank and March, Michael and Mangino, Massimo and Spector, Tim D and Bataille, Veronique and Pennell, Craig E and Holt, Patrick G and Sly, Peter and Tiesler, Carla M. T and Thiering, Elisabeth and Illig, Thomas and Imboden, Medea and Nystad, Wenche and Simpson, Angela and Hottenga, Jouke-Jan and Postma, Dirkje and Koppelman, Gerard H and Smit, Henriette A and Soderhall, Cilla and Chawes, Bo and Kreiner-Moller, Eskil and Bisgaard, Hans and Melen, Erik and Boomsma, Dorret I and Custovic, Adnan and Jacobsson, Bo and Probst-Hensch, Nicole M and Palmer, Lyle J and Glass, Daniel and Hakonarson, Hakon and Melbye, Mads and ... and Australian Asthma Genetics Consort and EArly Genetics Lifecourse Epidemio and Genetics Overweight Young Adults G and Genetics of Overweight Young Adults (GOYA) Consortium and Australian Asthma Genetics Consortium (AAGC) and EArly Genetics & Lifecourse Epidemiology (EAGLE) Consortium and The Genetics of Overweight Young Adults (GOYA) Consortium and the EArly Genetics & Lifecourse Epidemiology (EAGLE) Consortium and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Clinical Sciences, Section for the Health of Women and Children, Department of Obstetrics and Gynecology and Sahlgrenska Academy and Institutionen för kliniska vetenskaper, sektionen för kvinnors och barns hälsa, Avdelningen för obstetrik och gynekologi
Nature Genetics, ISSN 1061-4036, 02/2012, Volume 44, Issue 2, pp. 187 - 192
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 12/2010, Volume 191, Issue 7, pp. 1315 - 1332
Many protein kinases are activated by a conserved regulatory step involving T-loop phosphorylation. Although there is considerable focus on kinase activator... 
Phosphorylation | Phosphatases | Mitosis | Cell nucleus | Cell lines | HeLa cells | Small interfering RNA | Gene expression regulation | Chromosomes | Mitotic spindle apparatus | MITOSIS | SIGNALING PATHWAY | STRUCTURAL BASIS | CENTROSOME | A KINASE | CHROMOSOME SEGREGATION | POLO-LIKE KINASE | MYOSIN PHOSPHATASE | SOMATIC MUTATIONS | DROSOPHILA | CELL BIOLOGY | RNA, Small Interfering - genetics | Microtubule-Associated Proteins - genetics | Antigens, Nuclear - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Phosphoprotein Phosphatases - metabolism | Tubulin - genetics | Telophase - genetics | Protein Subunits - metabolism | Tubulin - metabolism | Holoenzymes - metabolism | Cell Nucleus - pathology | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | Phosphorylation - drug effects | Nuclear Proteins - genetics | Spindle Apparatus - physiology | Kinesin - antagonists & inhibitors | Protein-Serine-Threonine Kinases - metabolism | Protein Subunits - genetics | Proto-Oncogene Proteins - metabolism | Cell Line | Phosphoric Monoester Hydrolases - genetics | Catalytic Domain - genetics | Cell Cycle Proteins - metabolism | Nuclear Matrix-Associated Proteins - metabolism | Nuclear Proteins - metabolism | Aurora Kinases | Pyrimidines - pharmacology | Fibroblasts - pathology | Mutation - genetics | Kinesin - metabolism | Azepines - pharmacology | Anaphase - genetics | Histones - genetics | Phosphoprotein Phosphatases - genetics | Cell Nucleus - genetics | Mitosis - physiology | Models, Biological | Cyclin B - metabolism | Holoenzymes - genetics | Protein Kinase Inhibitors - pharmacology | Spindle Apparatus - drug effects | HeLa Cells | Histones - metabolism | Cell Nucleus - drug effects | Chromosome Segregation - genetics | Protein Binding - physiology | Spindle (Cell division) | Cellular proteins | Research | Properties | Phosphotransferases | Proteins | Cell division | Enzymes | Genotype & phenotype | Kinases | Index Medicus
Journal Article
International Journal of Oncology, ISSN 1019-6439, 12/2016, Volume 49, Issue 6, pp. 2255 - 2264
Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive malignancies. Recently developed molecular targeted therapies are not available for... 
esophageal squamous cell carcinoma | microRNA | tumor suppressor | matrix metalloproteinase 13 | miR-375 | Esophageal squamous cell carcinoma | MicroRNA | Matrix metalloproteinase 13 | Tumor suppressor | MiR-375 | Oncogene Proteins - genetics | RNA, Small Interfering - genetics | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Cell Movement - genetics | Esophageal Neoplasms - pathology | Poly-ADP-Ribose Binding Proteins | RNA Interference | Aged, 80 and over | Kinesin - genetics | Female | Microfilament Proteins - genetics | Esophageal Squamous Cell Carcinoma | Antigens, Neoplasm - genetics | Cell Proliferation - genetics | Matrix Metalloproteinase 13 - genetics | DNA-Binding Proteins - genetics | Chromosomal Proteins, Non-Histone - genetics | Esophageal Neoplasms - genetics | Cell Line, Tumor | DNA Topoisomerases, Type II - genetics | Neoplasm Recurrence, Local - genetics | Aged | MicroRNAs - genetics | Neoplasm Invasiveness - genetics | Care and treatment | Squamous cell carcinoma | Development and progression | Genetic aspects | Gene expression | Health aspects | Esophageal cancer | Cyclin-dependent kinases | Cell division | Kinases | Esophagus | Studies | Proteins | Cell growth | Insects | Medical prognosis | MicroRNAs | Dihydrofolate reductase | Cancer
Journal Article
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 12/2017, Volume 12, Issue 12, pp. 1974 - 1983
Background and objectives Genetic heterogeneity and phenotypic variability are major challenges in familial nephronophthisis and related ciliopathies. To date,... 
Prevalence | Nephronophthisis related ciliopathy | Ciliopathies | Joubert-like syndromes | NEPHREG registry | Bardet-Biedl syndrome | Senior-Løken syndrome | Congenital oculomotor apraxia | Genetic heterogeneity | Kidney diseases, cystic | Homozygote | Kidney failure, chronic | Nephronophthisis (NPH) | Adolescent | Mainzer-Saldino syndrome | Registries | Mutation | COACH syndrome | Nephronophthisis, familial juvenile | Cross-Sectional studies | ADOLESCENT NEPHRONOPHTHISIS | JOUBERT-SYNDROME | FAMILIAL JUVENILE NEPHRONOPHTHISIS | SENIOR-LOKEN SYNDROME | CYSTIC KIDNEY-DISEASE | GENE | RENAL-FAILURE | UROLOGY & NEPHROLOGY | NPHP3 | MUTATIONS | DOMAIN PROTEIN | Polyuria - genetics | Humans | Kidney Diseases, Cystic - diagnostic imaging | Male | Ciliopathies - complications | Nervous System Diseases - genetics | Young Adult | Ciliopathies - genetics | Anemia - genetics | Kidney - diagnostic imaging | Ultrasonography | Kidney Diseases, Cystic - genetics | Kinesin - genetics | Female | Glomerular Filtration Rate - genetics | Neoplasm Proteins - genetics | Child | Calmodulin-Binding Proteins - genetics | Kidney Failure, Chronic - physiopathology | Antigens, Neoplasm - genetics | Cross-Sectional Studies | Membrane Proteins - genetics | Kidney Failure, Chronic - genetics | Proteins - genetics | Carrier Proteins - genetics | Phenotype | Adaptor Proteins, Signal Transducing - genetics | Kidney Diseases, Cystic - complications | Kidney Diseases, Cystic - congenital | Longitudinal Studies | Index Medicus | Genetic Heterogeneity | Kidney Diseases, Cystic | Kidney Failure, Chronic | Original
Journal Article
Cancer Research, ISSN 0008-5472, 09/2013, Volume 73, Issue 17, pp. 5508 - 5518
The occurrence of inactivating mutations in SWI/SNF chromatin-remodeling genes in common cancers has attracted a great deal of interest. However, mechanistic... 
CELL LUNG-CANCER | ALK | ONCOLOGY | ADENOCARCINOMA | SENESCENCE | MUTATIONS | FUSIONS | DIFFERENTIATION | EXPRESSION | MEDULLOBLASTOMA | LINES | RNA, Small Interfering - genetics | Adenocarcinoma - pathology | Cell Proliferation | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Male | Immunoenzyme Techniques | Discoidin Domain Receptors | Cellular Senescence | Aged, 80 and over | Cell Differentiation | DNA Helicases - genetics | Carcinoma, Squamous Cell - therapy | Lung Neoplasms - therapy | Mutation - genetics | Blotting, Western | DNA Helicases - metabolism | Adenocarcinoma - therapy | Mice, Nude | Mice | Mice, Inbred BALB C | Carcinoma, Squamous Cell - genetics | Lung Neoplasms - pathology | Genes, Lethal | Kinesin - genetics | Adult | Female | Adenocarcinoma - genetics | Nuclear Proteins - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Transcription Factors - metabolism | Carcinoma, Non-Small-Cell Lung - therapy | Animals | Cell Cycle | Receptor Protein-Tyrosine Kinases - genetics | Oncogene Proteins, Fusion - genetics | Nuclear Proteins - antagonists & inhibitors | Fluorescent Antibody Technique | Aged | DNA Helicases - antagonists & inhibitors | Neoplasm Staging | Microscopy, Fluorescence | Apoptosis | Receptors, Mitogen - genetics | Index Medicus
Journal Article
PLoS Genetics, ISSN 1553-7390, 12/2016, Volume 12, Issue 12, pp. e1006469 - e1006469
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 02/2012, Volume 90, Issue 2, pp. 356 - 362
Journal Article