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Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 5315 - 13
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2017, Volume 199, Issue 9, pp. 3336 - 3347
Journal Article
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 07/2007, Volume 6, Issue 7, pp. 556 - 568
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, p. e0197350
Neurofibromatosis 2 (NF2) is a rare tumor suppressor syndrome that manifests with multiple schwannomas and meningiomas. There are no effective drug therapies... 
MOLECULE INHIBITOR | LAPATINIB | HISTONE DEACETYLASE INHIBITOR | ACTIVATION | MULTIDISCIPLINARY SCIENCES | THERAPEUTIC TARGET | PHASE-II | GROWTH-FACTOR | KINASE INHIBITOR | MENINGIOMA CELLS | VESTIBULAR SCHWANNOMAS | Neurofibromatosis 2 - drug therapy | Cell Survival - drug effects | Neurofibromin 2 - genetics | Meningeal Neoplasms - genetics | Humans | Panobinostat - pharmacology | Carcinogenesis - genetics | Gene Expression Regulation, Neoplastic | Morpholines - pharmacology | Transcriptome - genetics | Neurofibromatosis 2 - genetics | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Systems Biology | Neurilemmoma - pathology | Quinolines - pharmacology | Neurofibromatosis 2 - pathology | Animals | Meningeal Neoplasms - drug therapy | Neurilemmoma - drug therapy | Neurilemmoma - genetics | Cell Line, Tumor | Mice | Meningeal Neoplasms - pathology | Genetic aspects | Drug discovery | Research | Drug therapy | Systems biology | Neurofibromatosis | Cell culture | Pediatrics | Neurofibromin 2 | Neurofibromatosis 2 | Biology | Kinases | Medical schools | Consortia | Tumorigenesis | Bioinformatics | Phenotypes | Schwann cells | Breast cancer | Gene expression | Medical screening | Molecular chains | Children & youth | Medicine | Hospitals | Tumor suppressor genes | Blood diseases | Viability | Meningioma | Tumors
Journal Article
International Journal of Oncology, ISSN 1019-6439, 09/2017, Volume 51, Issue 3, pp. 841 - 850
Tyrosine phosphorylation is one of the basic mechanisms for signal transduction in the cell. Receptors exhibiting tyrosine kinase activity are widely involved... 
Adenocarcinoma | Tyrosine phosphatase | SAP-1 | DNA methylation | Colorectal tumor | Adenoma | Epigenetic | Gene expression | PTPRH | epigenetic | KINASE | adenocarcinoma | MUTATIONAL ANALYSIS | COLON-CANCER | tyrosine phosphatase | adenoma | KINOME | ONCOLOGY | GENE-EXPRESSION | gene expression | colorectal tumor | PROTEIN-TYROSINE-PHOSPHATASE | PCR | Index Medicus
Journal Article
BMC Medical Genomics, ISSN 1755-8794, 01/2014, Volume 7, Issue 1, pp. 4 - 4
Journal Article
Pediatric Blood & Cancer, ISSN 1545-5009, 11/2017, Volume 64, Issue 11, pp. e26551 - n/a
Purpose Malignant rhabdoid tumors (MRTs) are deadly embryonal tumors of the infancy. With poor survival and modest response to available therapies, more... 
PLK4 | CFI‐400495 | treatment | AT/RT | CRISPR/Cas9 | kinome | RTK | gene editing | Lentivirus | MRT | PLK4i | kinase | inhibitor | rhabdoid | CFI-400495 | HUMAN-CELLS | RADIATION SENSITIVITY | AURORA KINASE | CANCER | INHIBITION | GENE-EXPRESSION | PEDIATRICS | HEMATOLOGY | CENTRIOLE DUPLICATION | HUMAN GENOME | ONCOLOGY | CFI-400945 | ATYPICAL TERATOID/RHABDOID TUMORS | Humans | Brain Neoplasms - pathology | Rhabdoid Tumor - pathology | Larva - growth & development | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Indoles - pharmacology | Tumor Cells, Cultured | Protein-Serine-Threonine Kinases - metabolism | High-Throughput Screening Assays - methods | Amino Acid Sequence | Rhabdoid Tumor - drug therapy | Larva - metabolism | Protein-Serine-Threonine Kinases - genetics | Brain Neoplasms - genetics | Brain Neoplasms - drug therapy | Mutation - genetics | CRISPR-Cas Systems - genetics | Zebrafish - growth & development | Indazoles - pharmacology | Sequence Alignment | Animals | Rhabdoid Tumor - genetics | Zebrafish - metabolism | Cell Proliferation - drug effects | Cell Cycle - drug effects | Tumors, Embryonal | Polo | Gene expression | Health aspects | Genes | Brain tumors | Cell proliferation | Larvae | Brain | Pediatrics | Biotechnology | CRISPR | Cell survival | Toxicity | Cytotoxicity | Zebrafish | Tumor cell lines | Kinases | Survival | Screening | Cell growth | Inhibitors | DNA microarrays | Fibroblasts | Polo-like kinase | Viability | Tumors | Index Medicus
Journal Article