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neurosciences (158) 158
arcuate nucleus (151) 151
hormones, hormone substitutes, and hormone antagonists (149) 149
kisspeptins - pharmacology (149) 149
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abridged index medicus (139) 139
gonadotropin-releasing hormone - metabolism (137) 137
hypothalamus (133) 133
kisspeptins - genetics (130) 130
puberty (126) 126
luteinizing-hormone (124) 124
receptors, g-protein-coupled - metabolism (121) 121
expression (119) 119
gene-expression (117) 117
hypothalamus - metabolism (112) 112
estradiol - pharmacology (109) 109
luteinizing hormone - blood (108) 108
secretion (108) 108
kiss-1 (106) 106
hypogonadotropic hypogonadism (101) 101
metastasis-suppressor gene (101) 101
pharmacology & pharmacy (99) 99
gnrh (98) 98
hormones (98) 98
receptors, g-protein-coupled - genetics (96) 96
reproduction (96) 96
rna, messenger - metabolism (92) 92
brain (90) 90
endocrine system (88) 88
kiss1 protein (88) 88
gonadotropin-releasing hormone (87) 87
luteinizing hormone (87) 87
pituitary (85) 85
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biochemistry & molecular biology (82) 82
rats, sprague-dawley (81) 81
rats, wistar (80) 80
ovariectomy (79) 79
peptides (78) 78
luteinizing hormone - secretion (77) 77
reproductive biology (77) 77
monkey macaca-mulatta (76) 76
gene expression (75) 75
estradiol (72) 72
kisspeptin neurons (71) 71
pituitary-gonadal axis (71) 71
hypothalamus - drug effects (70) 70
pituitary hormones (70) 70
rodents (70) 70
arcuate nucleus of hypothalamus - metabolism (69) 69
messenger-rna (68) 68
physiological aspects (68) 68
analysis (66) 66
activation (65) 65
kiss1 (65) 65
luteinizing hormone - metabolism (64) 64
gene expression regulation - drug effects (62) 62
neurokinin b (62) 62
immunohistochemistry (61) 61
dose-response relationship, drug (60) 60
testosterone (60) 60
pregnancy (59) 59
neurons - physiology (58) 58
estrogen (56) 56
neurohormones (56) 56
oligopeptides - pharmacology (56) 56
tumor suppressor proteins - metabolism (56) 56
kiss-1 peptide (53) 53
proteins - metabolism (53) 53
signal transduction (53) 53
signal transduction - drug effects (53) 53
arcuate nucleus of hypothalamus - drug effects (52) 52
female rats (52) 52
mice, inbred c57bl (52) 52
time factors (52) 52
gonadotropin-releasing hormone - genetics (51) 51
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Endocrinology, ISSN 0013-7227, 08/2013, Volume 154, Issue 8, pp. 2750 - 2760
Kisspeptin neurons located in the arcuate nucleus (ARN) coexpress dynorphin and neurokinin B (NKB) and may interact to influence gonadotropin secretion. Using... 
GNRH PULSE-GENERATOR | HORMONE SECRETION | MORPHOLOGIC EVIDENCE | FEMALE MOUSE | IN-VITRO | MESSENGER-RNA EXPRESSION | PHARMACOLOGICAL CHARACTERIZATION | ENDOCRINOLOGY & METABOLISM | MEDIAN-EMINENCE | KAPPA-OPIOID RECEPTOR | SUBSTANCE-P | Receptors, Neurokinin-2 - antagonists & inhibitors | Receptors, Tachykinin - metabolism | Analgesics, Non-Narcotic - pharmacology | Arcuate Nucleus of Hypothalamus - cytology | Male | Peptide Fragments - pharmacology | Substance P - pharmacology | Green Fluorescent Proteins - genetics | Neurokinin B - pharmacology | Quinolines - pharmacology | Kisspeptins - genetics | Piperidines - pharmacology | Neurons - physiology | Receptors, Neurokinin-3 - metabolism | Neurons - metabolism | Receptors, Neurokinin-2 - metabolism | Dynorphins - metabolism | Neurons - drug effects | Substance P - analogs & derivatives | Receptors, Neurokinin-3 - antagonists & inhibitors | Membrane Potentials - drug effects | Green Fluorescent Proteins - metabolism | Arcuate Nucleus of Hypothalamus - metabolism | Receptors, Opioid, kappa - agonists | Receptors, Neurokinin-3 - agonists | Receptors, Opioid, kappa - metabolism | Mice, Transgenic | Kisspeptins - metabolism | 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer - pharmacology | Neurokinin B - metabolism | Patch-Clamp Techniques | Animals | Dynorphins - pharmacology | Kisspeptins - pharmacology | Mice | Oligopeptides - pharmacology | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2010, Volume 30, Issue 30, pp. 10205 - 10219
The neuropeptide kisspeptin is necessary for reproduction, fertility, and puberty. Here, we show strong kisspeptin innervation of hypothalamic anorexigenic... 
ENERGY-BALANCE | HORMONE PULSE-GENERATOR | HYPOTHALAMIC KISS-1 SYSTEM | REPRODUCTIVE FUNCTION | MESSENGER-RNA | FOOD-INTAKE | MORPHOLOGICAL EVIDENCE | NA+/CA2+ EXCHANGE INHIBITOR | ARCUATE NUCLEUS | NEUROSCIENCES | LUTEINIZING-HORMONE | Receptors, G-Protein-Coupled - metabolism | Arcuate Nucleus of Hypothalamus - cytology | Male | Neurons - cytology | Green Fluorescent Proteins - genetics | Thiourea - pharmacology | RNA, Messenger - metabolism | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Kisspeptins | Dose-Response Relationship, Drug | Excitatory Postsynaptic Potentials - physiology | Neuropeptide Y - metabolism | Egtazic Acid - analogs & derivatives | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Female | Sodium-Calcium Exchanger - antagonists & inhibitors | Neurons - metabolism | Neurons - drug effects | Membrane Potentials - drug effects | Tumor Suppressor Proteins - metabolism | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Axons - metabolism | Mice, Transgenic | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Imidazoles - pharmacology | Chelating Agents - pharmacology | Calcium Channel Blockers - pharmacology | Gene Expression Regulation - drug effects | Pro-Opiomelanocortin - metabolism | Renilla - genetics | Animals | Egtazic Acid - pharmacology | Tumor Suppressor Proteins - pharmacology | Mice | Receptors, G-Protein-Coupled - genetics | In Vitro Techniques | Receptors, Kisspeptin-1 | Thiourea - analogs & derivatives | Index Medicus
Journal Article
Endocrinology, ISSN 0013-7227, 01/2012, Volume 153, Issue 1, pp. 316 - 328
Kisspeptins (Kp), products of the Kiss1 gene that act via Gpr54 to potently stimulate GnRH secretion, operate as mediators of other regulatory signals of the... 
NMDA RECEPTOR | RECEPTORS ANTAGONIST | LUTEINIZING-HORMONE SECRETION | GPR54 | PEPTIDE KISSPEPTIN | ENDOCRINOLOGY & METABOLISM | NEURONS | ARCUATE NUCLEUS | HYPOGONADOTROPIC HYPOGONADISM | PUBERTY | KISS-1 PEPTIDE | Naltrexone - analogs & derivatives | Testosterone - physiology | Galanin-Like Peptide - pharmacology | Galanin-Like Peptide - physiology | Male | Peptide Fragments - pharmacology | Substance P - pharmacology | Neurokinin B - agonists | Kisspeptins - physiology | Naltrexone - pharmacology | Hypogonadism - physiopathology | Substance P - analogs & derivatives | Adamantane - analogs & derivatives | Luteinizing Hormone - secretion | Receptors, G-Protein-Coupled - physiology | Gonadotropin-Releasing Hormone - secretion | Hypogonadism - pathology | Adamantane - pharmacology | Neurokinin B - physiology | Dipeptides - pharmacology | Receptors, Neuropeptide - antagonists & inhibitors | Glutamic Acid - physiology | Gonadotropins - secretion | Receptors, N-Methyl-D-Aspartate - physiology | Mice, Knockout | Hypogonadism - genetics | Animals | Follicle Stimulating Hormone - secretion | Receptors, G-Protein-Coupled - deficiency | Receptors, N-Methyl-D-Aspartate - agonists | Signal Transduction - physiology | Mice | Receptors, G-Protein-Coupled - genetics | Models, Neurological | Receptors, Kisspeptin-1 | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2011, Volume 31, Issue 7, pp. 2421 - 2430
Journal Article
Endocrinology, ISSN 0013-7227, 10/2012, Volume 153, Issue 10, pp. 4818 - 4829
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, pp. e44344 - e44344
Kisspeptin, neurokinin B (NKB) and dynorphin A (Dyn) are coexpressed within KNDy neurons that project from the hypothalamic arcuate nucleus (ARC) to GnRH... 
GNRH PULSE-GENERATOR | MORPHOLOGIC EVIDENCE | MONKEY MACACA-MULATTA | FEMALE RAT | GONADOTROPIN-SECRETION | SEXUAL-MATURATION | MULTIDISCIPLINARY SCIENCES | STRESS-INDUCED SUPPRESSION | ARCUATE NUCLEUS | HYPOGONADOTROPIC HYPOGONADISM | KISSPEPTIN NEURONS | Naltrexone - analogs & derivatives | Receptors, Tachykinin - agonists | Antihypertensive Agents - pharmacology | Receptors, G-Protein-Coupled - metabolism | Receptors, Tachykinin - metabolism | Rats | Male | Peptide Fragments - pharmacology | Substance P - pharmacology | Neurokinin B - pharmacology | Kisspeptins - metabolism | 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer - pharmacology | Naltrexone - pharmacology | Neurokinin B - analogs & derivatives | Animals | Narcotic Antagonists - pharmacology | Radioimmunoassay | Bodily Secretions - drug effects | Receptors, G-Protein-Coupled - antagonists & inhibitors | Female | Receptors, Kisspeptin-1 | Substance P - analogs & derivatives | Luteinizing Hormone - secretion | Luteinizing hormone | Kinins | Cellular signal transduction | Research | Puberty | Neurosciences | Senktide | Narcotics | Neurons | Secretion | Arcuate nucleus | Neuropeptides | Monkeys | Dynorphin A | Hypothalamus | Medicine | Signaling | Neurokinin B | Neurokinin | Infertility | Rodents | Dynorphin | Gonadotropin-releasing hormone | Kiss1 protein | Endocrinology | Index Medicus
Journal Article
Journal Article
Endocrinology, ISSN 0013-7227, 09/2010, Volume 151, Issue 9, pp. 4494 - 4503
Journal Article
Journal Article
Neuroendocrinology, ISSN 0028-3835, 10/2014, Volume 99, Issue 3-4, pp. 190 - 203
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 08/2008, Volume 28, Issue 35, pp. 8691 - 8697
Journal Article
Endocrinology, ISSN 0013-7227, 08/2013, Volume 154, Issue 8, pp. 2761 - 2771
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 2, pp. e14671 - e14671
Splice products of the Kiss1 protein (kisspeptins) have been shown to be involved in a diverse range of functions, including puberty, metastasis and... 
ACTIVATION | HORMONE | RAT | PROTEIN-COUPLED RECEPTOR | KISS-1 | GPR54 | IN-VIVO | BIOLOGY | METASTASIS-SUPPRESSOR GENE | PEPTIDE | PREGNANCY | Pallor - chemically induced | Endothelin-1 - pharmacology | Humans | Microvessels - metabolism | Male | Substance P - pharmacology | Receptors, Calcitonin Gene-Related Peptide - metabolism | Dose-Response Relationship, Drug | Histamine Antagonists - pharmacology | Female | Kisspeptins - antagonists & inhibitors | RNA, Messenger - drug effects | Vasoconstrictor Agents - pharmacology | Vasoconstrictor Agents - antagonists & inhibitors | RNA, Messenger - genetics | Microvessels - drug effects | Organ Specificity | Vasoconstriction - drug effects | Indomethacin - pharmacology | Gene Expression Regulation - drug effects | Microvessels - physiology | Animals | Blood Circulation - drug effects | Edema - physiopathology | Kisspeptins - pharmacology | Mice | Receptors, G-Protein-Coupled - genetics | Edema - chemically induced | Receptors, Kisspeptin-1 | Pregnancy | Heart | Hypertension | Medical research | Histamine | RNA | Angiotensin | Albumin | Medicine, Experimental | Skin | Indomethacin | Syngeneic grafts | Kinases | Blood | Arteries | Metastases | Prostaglandin endoperoxide synthase | Biological effects | Vasoactive agents | Extravasation | Rodents | Aorta | Inhibition | Angiotensin II | Edema | Puberty | Kidneys | Vasoconstriction | Injection | Gene expression | Biological activity | Blood flow | Studies | Oxygenase | Womens health | Microvasculature | Kiss1 protein | Kidney transplantation | Index Medicus
Journal Article
Endocrinology, ISSN 0013-7227, 01/2012, Volume 153, Issue 1, pp. 307 - 315
Journal Article