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Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 10/2016, Volume 60, Issue 10, pp. 6115 - 6120
Hypervirulent Klebsiella pneumoniae (hvKP) is traditionally defined by hypermucoviscosity, but data based on genetic background are limited.... 
STRAINS | AEROBACTIN | VIRULENCE ANALYSIS | TAIWAN | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | SPECTRUM BETA-LACTAMASES | HONG-KONG | EMERGENCE | PYOGENIC LIVER-ABSCESS | Diabetes Mellitus - pathology | Prevalence | Prospective Studies | Klebsiella Infections - pathology | Humans | Middle Aged | Virulence | Male | Klebsiella pneumoniae - classification | Phylogeny | Multilocus Sequence Typing | Cross Infection - pathology | beta-Lactamases - genetics | Pneumonia, Bacterial - pathology | Gene Expression | Pneumonia, Bacterial - complications | Plasmids - metabolism | Cross Infection - microbiology | Diabetes Mellitus - epidemiology | Plasmids - chemistry | Bacteremia - epidemiology | Bacteremia - pathology | Neoplasms - epidemiology | Intraabdominal Infections - complications | Klebsiella pneumoniae - isolation & purification | Diabetes Complications | Cross Infection - complications | Bacteremia - microbiology | Neoplasms - complications | Klebsiella Infections - epidemiology | Klebsiella pneumoniae - genetics | Adult | Female | beta-Lactamases - metabolism | Cross Infection - epidemiology | Pneumonia, Bacterial - microbiology | Intraabdominal Infections - microbiology | Neoplasms - microbiology | Phylogeography | Bacteremia - complications | Bacterial Proteins - genetics | Serogroup | Klebsiella Infections - complications | Pneumonia, Bacterial - epidemiology | China - epidemiology | Klebsiella Infections - microbiology | Intraabdominal Infections - epidemiology | Diabetes Mellitus - microbiology | Intraabdominal Infections - pathology | Klebsiella pneumoniae - pathogenicity | Bacterial Proteins - metabolism | Aged | Neoplasms - pathology | Index Medicus
Journal Article
Journal Article
European Journal of Clinical Investigation, ISSN 0014-2972, 08/2015, Volume 45, Issue 8, pp. 824 - 832
BackgroundCatheter-related bloodstream infections (CRBSIs) are currently detected in patients with clinically suspicion. The aim of our study was to evaluate... 
haematooncology | screening | catheter‐related blood stream infection | peptide nucleic acid fluorescence in situ hybridization | Acridine orange leucocyte cytospin | Peptide nucleic acid fluorescence in situ hybridization | Screening | Catheter-related blood stream infection | Haematooncology | MEDICINE, RESEARCH & EXPERIMENTAL | DIAGNOSIS | MANAGEMENT | GUIDELINES | PREVENTION | SOCIETY | MEDICINE, GENERAL & INTERNAL | ONCOLOGY | peptide nucleic acid fluorescence insitu hybridization | BACTEREMIA | POSITIVITY | HEMATOLOGY | catheter-related blood stream infection | CULTURES | Enterobacteriaceae Infections - diagnosis | Fungemia - complications | Humans | Middle Aged | Male | Staphylococcal Infections - complications | Candidiasis - diagnosis | Enterobacteriaceae Infections - complications | Peptide Nucleic Acids | Adult | Female | Catheter-Related Infections - diagnosis | Hematologic Neoplasms - complications | Gram-Positive Bacterial Infections - complications | Stenotrophomonas maltophilia | Escherichia coli Infections - diagnosis | Central Venous Catheters | Bacteremia - complications | False Negative Reactions | Gram-Negative Bacterial Infections - complications | Pseudomonas Infections - complications | In Situ Hybridization, Fluorescence | Pseudomonas Infections - diagnosis | Bacteremia - diagnosis | Gram-Positive Bacterial Infections - diagnosis | Klebsiella Infections - complications | Fungemia - diagnosis | Candidiasis - complications | Staphylococcal Infections - diagnosis | Acridine Orange | Klebsiella Infections - diagnosis | Aged | Gram-Negative Bacterial Infections - diagnosis | Catheter-Related Infections - complications | Escherichia coli Infections - complications | Fluorescent Dyes | Cohort Studies | Index Medicus
Journal Article
European Journal of Clinical Investigation, ISSN 0014-2972, 01/2017, Volume 47, Issue 1, pp. 44 - 52
Background Spontaneous bacterial peritonitis (SBP) can be life threatening in patients with liver cirrhosis. In contrast to community-acquired SBP, no standard... 
Antibiotic | spontaneous bacterial peritonitis | ascites | liver | cirrhosis | resistance | MORTALITY | MEDICINE, RESEARCH & EXPERIMENTAL | INFECTIONS | RISK-FACTORS | PREVALENCE | LIVER-CIRRHOSIS | MEDICINE, GENERAL & INTERNAL | COMMUNITY | CIRRHOTIC-PATIENTS | COHORT | Prospective Studies | Humans | Middle Aged | Peritonitis - complications | Cross Infection | Drug Resistance, Bacterial | Male | Ceftriaxone | Bacterial Infections - complications | Anti-Bacterial Agents | Peritonitis - microbiology | Gram-Positive Bacterial Infections - microbiology | Female | Gram-Positive Bacterial Infections - complications | Thienamycins | Bacterial Infections - microbiology | Enterococcus | Streptococcal Infections - microbiology | Liver Cirrhosis - complications | Escherichia coli Infections - microbiology | Klebsiella Infections - complications | Klebsiella Infections - microbiology | Aged | Streptococcal Infections - complications | Ciprofloxacin | Escherichia coli Infections - complications | Moxalactam | Drug resistance in microorganisms | Cephalosporins | Liver | Cephaloridine | Cross infection | Nosocomial infections | Liver cirrhosis | Peritonitis | Klebsiella | Health care | Nosocomial infection | Escherichia coli | Piperacillin-tazobactam | Drug resistance | Patients | Quinolones | Cirrhosis | Microorganisms | Hospitals | Antibiotics | Tazobactam | Piperacillin | Antibiotic resistance | Bacteria | Meropenem | Carbapenems | Index Medicus
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 04/2017, Volume 61, Issue 4
Based upon knowledge of the hydrolytic profile of major-beta-lactamases found in Gram-negative bacteria, we tested the efficacy of the combination of... 
Metallo-β-lactamases | Avibactam | Disk diffusion | Ceftazidime | Aztreonam | GRAM-NEGATIVE INFECTIONS | ceftazidime | aztreonam | avibactam | PENICILLIN-BINDING PROTEINS | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | TIME | disk diffusion | INHIBITORS | metallo-beta-lactamases | KLEBSIELLA-PNEUMONIAE | Azabicyclo Compounds - pharmacology | Enterobacteriaceae - enzymology | Klebsiella pneumoniae - drug effects | Ceftazidime - pharmacology | Humans | Aztreonam - pharmacology | Colony Count, Microbial | Microbial Sensitivity Tests | Neutropenia - complications | beta-Lactamases - genetics | Neutropenia - microbiology | Klebsiella pneumoniae - genetics | Female | Soft Tissue Infections - drug therapy | beta-Lactamases - metabolism | Drug Therapy, Combination | Neutropenia - chemically induced | Enterobacteriaceae - growth & development | Gene Expression | Klebsiella Infections - drug therapy | Drug Administration Schedule | Enterobacteriaceae Infections - microbiology | Thigh | Enterobacteriaceae - genetics | Klebsiella Infections - complications | Klebsiella Infections - microbiology | Plasmids - metabolism | Neutropenia - drug therapy | Soft Tissue Infections - complications | Cyclophosphamide | Animals | Soft Tissue Infections - microbiology | Enterobacteriaceae - drug effects | Klebsiella pneumoniae - enzymology | Plasmids - chemistry | Klebsiella pneumoniae - growth & development | Anti-Bacterial Agents - pharmacology | Mice | beta-Lactam Resistance - genetics | Enterobacteriaceae Infections - drug therapy | beta-Lactam Resistance - drug effects | Index Medicus
Journal Article
BMC Gastroenterology, ISSN 1471-230X, 07/2014, Volume 14, Issue 1, pp. 133 - 133
Background: Although pyogenic liver abscess (PPLA) fatalities are decreasing owing to early diagnosis and effective treatments, PPLA-associated complications... 
Outcome complications | Initial presentation | Primary pyogenic liver abscess | Mortality | Risk factors | ETIOLOGY | DIAGNOSIS | SINGLE | EMPHASIS | CLINICAL-COURSE | GASTROENTEROLOGY & HEPATOLOGY | KLEBSIELLA-PNEUMONIAE | Escherichia coli Infections - mortality | Prognosis | Humans | Middle Aged | Male | Staphylococcal Infections - complications | Jaundice - complications | Fusobacterium Infections - mortality | Young Adult | Fusobacterium Infections - diagnosis | Neoplasms - complications | Liver - diagnostic imaging | Respiratory Distress Syndrome, Adult - complications | Ultrasonography | Aged, 80 and over | Adult | Female | Retrospective Studies | Child | Liver Abscess, Pyogenic - complications | Escherichia coli Infections - diagnosis | Cross-Sectional Studies | Logistic Models | Klebsiella Infections - complications | Liver Abscess, Pyogenic - diagnosis | Endophthalmitis - complications | Hypotension - complications | Radiography | Staphylococcal Infections - mortality | Staphylococcal Infections - diagnosis | Liver Abscess, Pyogenic - mortality | Adolescent | Sex Factors | Taiwan | Klebsiella Infections - diagnosis | Klebsiella Infections - mortality | Aged | Fusobacterium Infections - complications | Escherichia coli Infections - complications | Rupture, Spontaneous | Medical imaging | Disease | Internal medicine | Review boards | Liver | Medical records | Drug resistance | Epidemiology | Studies | Ultrasonic imaging | Hospitals | Antibiotics | Gastroenterology | Tomography | Population | Hospital systems | Index Medicus
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 09/2016, Volume 63, Issue 6, pp. 754 - 762
Background. The global emergence of carbapenem-resistant Enterobacteriaceae highlights the urgent need to reduce carbapenem dependence. The phase 3 RECAPTURE... 
acute pyelonephritis | ceftazidime-avibactam | complicated urinary tract infection | INFECTIOUS DISEASES | INITIAL ANTIBIOTIC-THERAPY | ANTIMICROBIAL THERAPY | MICROBIOLOGY | IMMUNOLOGY | INTRAABDOMINAL INFECTION | CARBAPENEM-RESISTANT ENTEROBACTERIACEAE | TREATMENT OPTIONS | BACTERICIDAL ACTIVITY | PSEUDOMONAS-AERUGINOSA | LACTAMASE-PRODUCING ENTEROBACTERIACEAE | SPECTRUM BETA-LACTAMASES | KLEBSIELLA-PNEUMONIAE | Doripenem | Azabicyclo Compounds - administration & dosage | Carbapenems - administration & dosage | Humans | Middle Aged | Male | Pyelonephritis - complications | Urinary Tract Infections - complications | Urinary Tract Infections - drug therapy | Carbapenems - adverse effects | Anti-Bacterial Agents - therapeutic use | Carbapenems - therapeutic use | Ceftazidime - administration & dosage | Adult | Azabicyclo Compounds - therapeutic use | Female | Aged | Anti-Bacterial Agents - adverse effects | Ceftazidime - adverse effects | Pyelonephritis - drug therapy | Anti-Bacterial Agents - administration & dosage | Ceftazidime - therapeutic use | Drug Combinations | Azabicyclo Compounds - adverse effects | Care and treatment | Usage | Pyelonephritis | Clinical trials | Urinary tract infections | Influence | Dosage and administration | Ceftazidime | Antibiotics | Drug resistance | Drug therapy | CRE bacteria | Urinary tract diseases | Index Medicus | and Commentaries
Journal Article
Infection control and hospital epidemiology, ISSN 0899-823X, 08/2015, Volume 36, Issue 8, pp. 981 - 985
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, pp. e56022 - e56022
Background: Staphylococcus aureus remains the predominant pathogen in diabetic foot infections and prevalence of methicillin resistant S. aureus (MRSA) strains... 
SOFT-TISSUE INFECTIONS | BACTERIAL-INFECTIONS | VANCOMYCIN | PHARMACOKINETICS | MULTIDISCIPLINARY SCIENCES | PENETRATION | PHAGE THERAPY | MICE | MELLITUS | KLEBSIELLA-PNEUMONIAE | COMPLICATED SKIN | Bacteriophages | Diabetic Foot - complications | Linezolid | Diabetes Mellitus, Experimental - drug therapy | Staphylococcal Skin Infections - complications | Diabetic Foot - drug therapy | Anti-Infective Agents - therapeutic use | Treatment Outcome | Diabetic Foot - microbiology | Oxazolidinones - therapeutic use | Anti-Bacterial Agents - therapeutic use | Staphylococcal Skin Infections - drug therapy | Animals | Acetamides - therapeutic use | Anti-Bacterial Agents - pharmacology | Diabetes Mellitus, Experimental - complications | Diabetes Mellitus, Experimental - microbiology | Mice | Mice, Inbred BALB C | Methicillin-Resistant Staphylococcus aureus - isolation & purification | Staphylococcal Skin Infections - microbiology | Infection | Type 2 diabetes | Diabetics | Drug resistance in microorganisms | Usage | Analysis | Staphylococcus aureus infections | Diabetic foot | Health aspects | Staphylococcus aureus | Therapy | Pneumonia | Costs | Laboratories | Phages | Diabetic neuropathy | Infections | Drug resistance | Methicillin | Immunology | Bacteria | Peroxidase | Strains (organisms) | Bacterial infections | Wound healing | Mortality | Diabetes mellitus | Neutrophils | Staphylococcus infections | FDA approval | Patients | Mutants | Feet | Alloxan | Immunosuppression | Infectious diseases | Antibiotics | Ulcers | Arresting (process) | Host range | Healing | Diabetes | Foot diseases | Index Medicus
Journal Article
American Journal of Emergency Medicine, ISSN 0735-6757, 2014, Volume 32, Issue 10, pp. 1241 - 1247
Abstract Objectives The objective of this study is to analyze the differences in clinical presentation and outcome of community-onset bacteremia between human... 
Emergency | MULTICENTER | RISK-FACTORS | EMERGENCY-DEPARTMENT | HIV | EMERGENCY MEDICINE | SEPTIC SHOCK | RESISTANCE | ANTIBIOTIC-TREATMENT | BACTERIAL | NOSOCOMIAL INFECTIONS | SEVERE SEPSIS | Escherichia coli Infections - mortality | Multivariate Analysis | Age Factors | Endocarditis, Bacterial - mortality | Humans | Middle Aged | Bacteremia - mortality | Male | Staphylococcal Infections - complications | Urinary Tract Infections - complications | Case-Control Studies | Bacteremia - microbiology | Aged, 80 and over | Endocarditis, Bacterial - microbiology | Adult | Female | Urinary Tract Infections - microbiology | Community-Acquired Infections - complications | Retrospective Studies | Severity of Illness Index | Community-Acquired Infections - mortality | Emergency Service, Hospital | Salmonella Infections - complications | Bacteremia - complications | Shock, Septic - complications | Logistic Models | Klebsiella Infections - complications | Salmonella Infections - mortality | Endocarditis, Bacterial - complications | Hepatitis - complications | Shock, Septic - microbiology | Staphylococcal Infections - mortality | HIV Infections - complications | Sex Factors | Taiwan | Klebsiella Infections - mortality | Aged | Community-Acquired Infections - microbiology | Escherichia coli Infections - complications | HIV patients | Bacteremia | Health facilities | Laboratories | Mortality | Infections | Hospitalization | Multivariate analysis | Disease control | Epidemiology | Confidence intervals | Identification systems | Hospitals | Antibiotics | E coli | Human immunodeficiency virus--HIV | Urogenital system | Index Medicus
Journal Article
BMC Infectious Diseases, ISSN 1471-2334, 10/2010, Volume 10, Issue 1, pp. 307 - 307
Background: Klebsiella pneumoniae is the major cause of community-acquired pyogenic infections in Taiwan. This retrospective study evaluated the clinical and... 
MORTALITY | INFECTIOUS DISEASES | INFECTIONS | STREPTOCOCCUS-PNEUMONIAE | THERAPY | MONOTHERAPY | SEROTYPE K1 | LIVER-ABSCESS | PNEUMOCOCCAL PNEUMONIA | VIRULENCE | Klebsiella pneumoniae - isolation & purification | Klebsiella Infections - pathology | Humans | Middle Aged | Bacteremia - mortality | Male | Bacteremia - microbiology | Streptococcus pneumoniae - isolation & purification | Pneumonia, Bacterial - mortality | Aged, 80 and over | Adult | Female | Pneumococcal Infections - microbiology | Community-Acquired Infections - complications | Retrospective Studies | Pneumonia, Bacterial - pathology | Community-Acquired Infections - mortality | Pneumococcal Infections - complications | Pneumonia, Bacterial - microbiology | Pneumonia, Bacterial - complications | Risk Factors | Pneumococcal Infections - pathology | Pneumococcal Infections - mortality | Klebsiella Infections - complications | Klebsiella Infections - microbiology | Shock, Septic - mortality | Community-Acquired Infections - pathology | Taiwan | Klebsiella Infections - mortality | Aged | Bacteremia - pathology | Community-Acquired Infections - microbiology | Klebsiella | Pneumonia | Bacterial pneumonia | Patient outcomes | Distribution | Causes of | Research | Identification and classification | Bacteremia | Confidence intervals | Genotype & phenotype | Tuberculosis | Antibiotics | Microbiology | Mortality | Data collection | Hospitalization | Multivariate analysis | Risk factors | Streptococcus infections | Index Medicus
Journal Article