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Journal Article
Journal Article
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 2015, Volume 70, Issue 12, pp. 3230 - 3237
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 02/2019, Volume 116, Issue 9, pp. 3774 - 3783
Establishing causal links between bacterial metabolites and human intestinal disease is a significant challenge. This study reveals the molecular basis of... 
STRAINS | DNA damage | MULTIDISCIPLINARY SCIENCES | ANTHRAMYCIN | MICROBIOME | NUCLEOTIDE EXCISION-REPAIR | intestinal microbiota | tubulin inhibitor | COLITIS | PRODUCTS | antibiotic-induced diarrhea | BIOSYNTHESIS | TARGETS | PYRROLOBENZODIAZEPINE | BINDING | dysbiosis | Benzodiazepinones - metabolism | Klebsiella oxytoca - genetics | Host Microbial Interactions - genetics | Humans | Enterocolitis, Pseudomembranous - microbiology | Klebsiella oxytoca - pathogenicity | Peptides - metabolism | Peptides - toxicity | Oxyquinoline - metabolism | Microtubules - drug effects | Benzodiazepinones - toxicity | Oxyquinoline - toxicity | DNA Damage - drug effects | Intestines - pathology | Enterocolitis, Pseudomembranous - genetics | Epithelial Cells - pathology | Klebsiella Infections - genetics | Klebsiella Infections - microbiology | Klebsiella oxytoca - metabolism | Enterocolitis, Pseudomembranous - pathology | Enterotoxins - biosynthesis | Animals | Intestines - microbiology | Epithelial Cells - microbiology | Enterotoxins - metabolism | Mice | Oxyquinoline - analogs & derivatives | Klebsiella | Molecular structure | Peptides | Epithelial cells | Hemorrhage | DNA repair | Microbiota | Tubulin | Metabolites | Intestine | Damage | Deoxyribonucleic acid--DNA | Pathogens | Enterotoxins | Cecum | Pathogenicity | Inflammatory bowel disease | Enterocytes | Antibiotics | Breakage | Microtubules | Toxins | Colitis | Apoptosis | Biological Sciences | PNAS Plus
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, p. e100542
Klebsiella oxytoca is an opportunistic pathogen implicated in various clinical diseases in animals and humans. Studies suggest that in humans K. oxytoca exerts... 
HEMORRHAGIC COLITIS | ANTIBIOTIC-ASSOCIATED DIARRHEA | OXYGEN-TENSION | UTEROOVARIAN INFECTION | TOXIN | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | TILIVALLINE | INDUCED ENTEROCOLITIS SYNDROME | IDENTIFICATION | B6C3F1 MICE | Benzodiazepinones - metabolism | Plant Extracts - pharmacology | Humans | Bacterial Toxins - toxicity | Benzodiazepinones - isolation & purification | Bacterial Toxins - isolation & purification | Klebsiella oxytoca - pathogenicity | Swine | Benzodiazepinones - toxicity | Klebsiella Infections - veterinary | Cell Death - drug effects | Klebsiella oxytoca - drug effects | Cell Line | Cell Survival - drug effects | Bacterial Secretion Systems - genetics | Rats | Plant Extracts - isolation & purification | Klebsiella Infections - microbiology | Klebsiella oxytoca - isolation & purification | Klebsiella oxytoca - metabolism | Bacterial Toxins - chemistry | Benzodiazepinones - chemistry | Haplorhini | Bacterial Toxins - biosynthesis | Soybeans - chemistry | Animals | Mice | HeLa Cells | Proteins | Cholera toxin | Nucleotide sequencing | Virulence (Microbiology) | Genomics | DNA sequencing | Klebsiella | Bioengineering | Cell culture | Soybeans | Pathogenesis | Virulence | Opportunist infection | Animal diseases | Cytotoxicity | Gene sequencing | Magnetic resonance spectroscopy | Urinary tract infections | Nosocomial infections | Public health | Pathogens | Mass spectroscopy | Liquid chromatography | Benzodiazepines | Urinary tract diseases | Pathogenicity | Inflammatory bowel disease | Laboratory tests | Diagnostic software | Biomarkers | Toxins | NMR spectroscopy | Mass spectrometry | Water-borne diseases | Toxicity | Genes | Leukemia | Clinical isolates | Infections | Genomes | Molecular weight | Engineering | E coli | Low molecular weights | Bacteria | Urogenital system | Campylobacter | Environmental regulations | Secretion | Medicine | Antibiotics | Cell lines | Cholera | Diagnostic systems | Laboratory animals
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2015, Volume 10, Issue 11, p. e0142366
We characterized 12 clinical isolates of Klebsiella oxytoca with the extended-spectrum beta-lactamase (ESBL) phenotype (high minimum inhibitory concentration... 
STRAINS | HEMORRHAGIC COLITIS | OVERPRODUCTION | PROMOTERS | MULTIDISCIPLINARY SCIENCES | SPECTRUM BETA-LACTAMASE | HOSPITALS | TAZOBACTAM | PNEUMONIAE | EPIDEMIOLOGY | ENTEROBACTERIACEAE | Klebsiella oxytoca - genetics | Escherichia coli - drug effects | Humans | Middle Aged | Male | Anti-Bacterial Agents - therapeutic use | beta-Lactamases - genetics | Disease Outbreaks | Penicillanic Acid - therapeutic use | Adult | Female | Penicillanic Acid - analogs & derivatives | Klebsiella oxytoca - drug effects | Escherichia coli Infections - drug therapy | Klebsiella Infections - drug therapy | Japan | Escherichia coli Infections - microbiology | Klebsiella Infections - microbiology | Klebsiella oxytoca - isolation & purification | Cross Infection - drug therapy | Multilocus Sequence Typing - methods | Escherichia coli - genetics | Cross Infection - microbiology | Adolescent | Aged | Drug Resistance, Multiple, Bacterial - genetics | beta-Lactams - therapeutic use | Microbial Sensitivity Tests - methods | Piperacillin - therapeutic use | Klebsiella | Nosocomial infection | Pneumonia | Laboratories | Genes | Clinical isolates | Outbreaks | Ceftriaxone | Pulsed-field gel electrophoresis | E coli | Piperacillin | Isoelectric focusing | Genotypes | Deoxyribonucleic acid--DNA | University graduates | Gel electrophoresis | Agar | Bacteriology | Medicine | Screening | Dilution | Infectious diseases | Hospitals | Tazobactam | Antibiotics | Minimum inhibitory concentration | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
Journal Article