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JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, ISSN 0098-7484, 09/2018, Volume 320, Issue 10, pp. 984 - 994
IMPORTANCE Extended-spectrum beta-lactamases mediate resistance to third-generation cephalosporins (eg, ceftriaxone) in Escherichia coli and Klebsiella... 
UNITED-STATES | MEDICINE, GENERAL & INTERNAL | EXTENDED-SPECTRUM | CEFEPIME | THERAPY | BACTEREMIA | LACTAMASE-PRODUCING ENTEROBACTERIACEAE | SPECTRUM BETA-LACTAMASES | EXTENSION | Escherichia coli Infections - mortality | Klebsiella pneumoniae - drug effects | Escherichia coli - drug effects | Humans | Middle Aged | Drug Resistance, Bacterial | Bacteremia - mortality | Ceftriaxone - pharmacology | Male | Cause of Death | Anti-Bacterial Agents - therapeutic use | Penicillanic Acid - therapeutic use | Adult | Female | Anti-Bacterial Agents - adverse effects | Meropenem | Penicillanic Acid - adverse effects | Thienamycins - adverse effects | Penicillanic Acid - analogs & derivatives | Thienamycins - therapeutic use | Escherichia coli Infections - drug therapy | Klebsiella Infections - drug therapy | Piperacillin, Tazobactam Drug Combination | Bacteremia - drug therapy | Piperacillin - adverse effects | Klebsiella Infections - mortality | Aged | Anti-Bacterial Agents - pharmacology | Piperacillin - therapeutic use | Klebsiella | Treatment outcome | Safety and security measures | Tazobactam | Escherichia coli | Patient outcomes | Analysis | Comparative analysis | Risk factors | Bacterial infections | Intravenous administration | Mortality | Clinical trials | Piperacillin-tazobactam | Infections | Ceftriaxone | Drug resistance | Patients | Side effects | Randomization | Cephalosporins | E coli | Piperacillin | Drug therapy | Blood diseases | Blood culture | Carbapenems | Original Investigation | Research
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