X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (1474) 1474
ku autoantigen (1336) 1336
humans (1038) 1038
dna-binding proteins - metabolism (837) 837
dna-binding proteins - genetics (729) 729
animals (723) 723
dna repair (600) 600
biochemistry & molecular biology (537) 537
dna helicases (499) 499
antigens, nuclear - metabolism (494) 494
antigens, nuclear (453) 453
antigens, nuclear - genetics (436) 436
dna (395) 395
dna damage (381) 381
cell biology (380) 380
vj recombination (380) 380
mice (378) 378
nuclear proteins - metabolism (359) 359
dependent protein-kinase (314) 314
nuclear proteins - genetics (274) 274
cell line (267) 267
repair (248) 248
proteins (241) 241
molecular sequence data (233) 233
oncology (228) 228
protein binding (223) 223
double-strand breaks (222) 222
dna breaks, double-stranded (220) 220
female (219) 219
strand break repair (219) 219
dna-activated protein kinase (213) 213
base sequence (212) 212
genetics & heredity (210) 210
dna - metabolism (197) 197
hela cells (197) 197
male (197) 197
homologous recombination (196) 196
mutation (195) 195
research (188) 188
mammalian-cells (187) 187
cells (182) 182
dna-binding proteins - physiology (178) 178
saccharomyces-cerevisiae (178) 178
cancer (173) 173
phosphorylation (173) 173
protein-serine-threonine kinases - metabolism (172) 172
dna repair - genetics (166) 166
recombination, genetic (166) 166
apoptosis (156) 156
catalytic subunit (153) 153
dna-binding proteins - chemistry (149) 149
ionizing-radiation (143) 143
multidisciplinary sciences (143) 143
ku70 (141) 141
cell line, tumor (139) 139
cricetinae (134) 134
genetic aspects (134) 134
article (133) 133
expression (131) 131
protein (127) 127
enzymes and coenzymes (125) 125
amino acid sequence (123) 123
genes (123) 123
dna-activated protein kinase - metabolism (120) 120
middle aged (120) 120
binding (116) 116
gene (116) 116
transfection (114) 114
dna - genetics (113) 113
deoxyribonucleic acid--dna (111) 111
biology (108) 108
gene expression (108) 108
complex (107) 107
saccharomyces cerevisiae proteins (106) 106
deoxyribonucleic acid (103) 103
nuclear proteins - physiology (103) 103
fungi (100) 100
mice, knockout (99) 99
analysis (98) 98
cho cells (98) 98
blotting, western (95) 95
binding sites (93) 93
adult (92) 92
aged (92) 92
biophysics (92) 92
ku autoantigen - metabolism (92) 92
cell cycle (90) 90
ku protein (90) 90
ku80 (89) 89
saccharomyces cerevisiae - genetics (89) 89
toxicology (88) 88
non-homologous end joining (87) 87
cell nucleus - metabolism (86) 86
dna repair - physiology (86) 86
recombination (86) 86
protein-serine-threonine kinases - genetics (85) 85
cells, cultured (84) 84
dna end-joining repair (84) 84
dna-repair (83) 83
genetic research (83) 83
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Molecular Cell, ISSN 1097-2765, 08/2017, Volume 67, Issue 3, pp. 387 - 399.e5
The DNA-mediated innate immune response underpins anti-microbial defenses and certain autoimmune diseases. Here we used immunoprecipitation, mass spectrometry,... 
HEXIM1 | DNA-PK | innate immune response | herpesvirus | paraspeckles | cGAS | NEAT1 | interferon stimulatory DNA | DEFENSE | PROTEIN | INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | SENSOR | POLYMERASE-II | 7SK RNA | BINDING | GMP-AMP SYNTHASE | P-TEFB | CELL BIOLOGY | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Octamer Transcription Factors - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Herpesvirus 8, Human - immunology | RNA, Long Noncoding - immunology | PTB-Associated Splicing Factor - genetics | RNA Interference | Calcium-Binding Proteins - immunology | Octamer Transcription Factors - genetics | Nucleotidyltransferases - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Signal Transduction | Membrane Proteins - genetics | RNA-Binding Proteins - immunology | PTB-Associated Splicing Factor - metabolism | Nuclear Matrix-Associated Proteins - metabolism | PTB-Associated Splicing Factor - immunology | DNA - metabolism | Host-Pathogen Interactions | Nuclear Matrix-Associated Proteins - genetics | HeLa Cells | RNA-Binding Proteins - metabolism | Calcium-Binding Proteins - genetics | RNA-Binding Proteins - genetics | Multiprotein Complexes | Human Umbilical Vein Endothelial Cells - immunology | Intracellular Signaling Peptides and Proteins - immunology | Human Umbilical Vein Endothelial Cells - virology | Interferon Regulatory Factor-3 - genetics | Ku Autoantigen - genetics | Transfection | HEK293 Cells | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Octamer Transcription Factors - metabolism | Interferon Regulatory Factor-3 - immunology | Calcium-Binding Proteins - metabolism | DNA - immunology | Nuclear Matrix-Associated Proteins - immunology | Ku Autoantigen - immunology | Membrane Proteins - immunology | Nuclear Proteins - metabolism | Ku Autoantigen - metabolism | RNA, Long Noncoding - genetics | Immunity, Innate | Nuclear Proteins - immunology | DNA - genetics | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein Binding | Nucleotidyltransferases - immunology | RNA, Long Noncoding - metabolism | RNA sequencing | Immune response | RNA | DNA | Genetic research | Interferon | Biological response modifiers | Mass spectrometry | Index Medicus | Human Umbilical Vein Endothelial Cells | Nuclear Matrix-Associated Proteins | Herpesvirus 8, Human | RNA-Binding Proteins | Life Sciences | Interferon Regulatory Factor-3 | Genetics | Calcium-Binding Proteins | Intracellular Signaling Peptides and Proteins | PTB-Associated Splicing Factor | Nuclear Proteins | Membrane Proteins | Nucleotidyltransferases | Ku Autoantigen | Octamer Transcription Factors | RNA, Long Noncoding
Journal Article
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2016, Volume 291, Issue 53, pp. 26987 - 27006
DNA double-strand break (DSB) repair by non-homologous end joining (NHEJ) in human cells is initiated by Ku heterodimer binding to a DSB, followed by... 
REPAIR PROTEINS | STRUCTURAL INSIGHTS | DAMAGE RESPONSE | BIOLOGICAL MACROMOLECULES | SMALL-ANGLE SCATTERING | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEPENDENT PROTEIN-KINASE | DOUBLE-STRAND BREAKS | X-RAY-SCATTERING | IONIZING-RADIATION | Phosphorylation | Immunoprecipitation | Humans | DNA Breaks, Double-Stranded | DNA-Activated Protein Kinase - chemistry | DNA-Binding Proteins - metabolism | Poly-ADP-Ribose Binding Proteins | DNA-(Apurinic or Apyrimidinic Site) Lyase - genetics | Ku Autoantigen - genetics | DNA Ligase ATP - genetics | X-Ray Diffraction | DNA-Activated Protein Kinase - genetics | DNA-Activated Protein Kinase - metabolism | DNA Ligase ATP - metabolism | Nuclear Proteins - genetics | Cross-Linking Reagents | DNA End-Joining Repair - genetics | Ku Autoantigen - chemistry | Models, Molecular | Scattering, Small Angle | Nuclear Proteins - metabolism | Ku Autoantigen - metabolism | DNA-Binding Proteins - genetics | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Blotting, Western | DNA-(Apurinic or Apyrimidinic Site) Lyase - chemistry | DNA-(Apurinic or Apyrimidinic Site) Lyase - metabolism | DNA Ligase ATP - chemistry | Protein Binding | Protein Conformation | HeLa Cells | Index Medicus | DNA-dependent serine/threonine protein kinase (DNA-PK) | small-angle x-ray scattering (SAXS) | INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY | intrinsically disordered protein | XRCC4 | BASIC BIOLOGICAL SCIENCES | APLF | DNA ligase IV | non-homologous end joining | protein complex | DNA repair | DNA and Chromosomes | small-angle X-ray scattering (SAXS) | DNA-dependent serine | threonine protein kinase (DNA-PK)
Journal Article
Journal Article
DNA Repair, ISSN 1568-7864, 07/2016, Volume 43, pp. 98 - 106
Non-Homologous End-Joining (NHEJ) is the predominant pathway for the repair of DNA double strand breaks (DSBs) in human cells. The NHEJ pathway is frequently... 
Chemotherapy | Ku70/80 | Non-Homologous End-Joining | DNA double strand break | Small molecule inhibitor | Radiation | CELLS | HUMAN PROSTATE | KINASE | CANCER | BIOLOGY | GENETICS & HEREDITY | TOXICOLOGY | DNA-Activated Protein Kinase - antagonists & inhibitors | Gamma Rays | Small Molecule Libraries - pharmacology | Pyrimidines - chemical synthesis | Humans | Protein Multimerization | Crystallography, X-Ray | DNA Breaks, Double-Stranded | DNA-Activated Protein Kinase - chemistry | Ku Autoantigen - antagonists & inhibitors | Ku Autoantigen - genetics | DNA-Activated Protein Kinase - genetics | DNA-Activated Protein Kinase - metabolism | Protein Domains | Nuclear Proteins - genetics | DNA End-Joining Repair - drug effects | Recombinant Proteins - metabolism | Cell Survival - drug effects | Gene Expression | Protein Structure, Secondary | Ku Autoantigen - chemistry | Small Molecule Libraries - chemical synthesis | Nuclear Proteins - metabolism | Ku Autoantigen - metabolism | Recombinant Proteins - genetics | DNA - metabolism | Pyrimidines - pharmacology | Nuclear Proteins - chemistry | Cell Survival - radiation effects | DNA - genetics | Nuclear Proteins - antagonists & inhibitors | Molecular Docking Simulation | HeLa Cells | Ionizing radiation | DNA | DNA repair | Cells | Cancer | Medical imaging equipment | Index Medicus
Journal Article
Immunologic Research, ISSN 0257-277X, 04/2017, Volume 65, Issue 2, pp. 564 - 571
Etiology, pathogenesis, and immunology of systemic lupus erythematosus (SLE) form a complex, still undeciphered picture that recently has been further made... 
HERV | Crossreactivity | EBV | SLE | HPV | LOW-SIMILARITY | AUTOANTIGEN | IMMUNOLOGY | TYROSINE-PHOSPHATASE | DEFICIENCY | ENDOGENOUS RETROVIRUSES | FUNCTIONAL VARIANT | MOLECULAR MIMICRY | ASSOCIATION | EXPRESSION | EPSTEIN-BARR-VIRUS | Autoimmunity | Epitope Mapping | Humans | Antigens, CD19 - genetics | Antibodies, Viral - blood | Receptors, Natural Killer Cell - immunology | Ku Autoantigen - genetics | Papillomaviridae - immunology | Peptide Fragments - immunology | Lupus Erythematosus, Systemic - immunology | Capsid Proteins - immunology | Papillomavirus Infections - immunology | Oncogene Proteins, Viral - genetics | Papillomavirus Infections - virology | Peptide Fragments - genetics | Antigens, CD19 - immunology | Oncogene Proteins, Viral - metabolism | Peptide Fragments - metabolism | Complement C4 - metabolism | Capsid Proteins - metabolism | Lupus Erythematosus, Systemic - virology | Receptors, Natural Killer Cell - metabolism | Ku Autoantigen - immunology | Ku Autoantigen - metabolism | Complement C4 - immunology | Complement C4 - genetics | Cross Reactions | Papillomavirus Vaccines - immunology | Antigens, CD19 - metabolism | Oncogene Proteins, Viral - immunology | Capsid Proteins - genetics | Receptors, Natural Killer Cell - genetics | Proteins | Lupus | Antigens | Killer cells | Systemic lupus erythematosus | Analysis | Transplantation of organs, tissues, etc | Development and progression | Health aspects | Papillomavirus infections | Human papillomavirus | Hypotheses | Immune response | Immunology | Peptides | Autoimmune diseases | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2016, Volume 64, Issue 1, pp. 189 - 198
Journal Article