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Molecular Cell, ISSN 1097-2765, 08/2017, Volume 67, Issue 3, pp. 387 - 399.e5
The DNA-mediated innate immune response underpins anti-microbial defenses and certain autoimmune diseases. Here we used immunoprecipitation, mass spectrometry,... 
HEXIM1 | DNA-PK | innate immune response | herpesvirus | paraspeckles | cGAS | NEAT1 | interferon stimulatory DNA | DEFENSE | PROTEIN | INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | SENSOR | POLYMERASE-II | 7SK RNA | BINDING | GMP-AMP SYNTHASE | P-TEFB | CELL BIOLOGY | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Octamer Transcription Factors - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Herpesvirus 8, Human - immunology | RNA, Long Noncoding - immunology | PTB-Associated Splicing Factor - genetics | RNA Interference | Calcium-Binding Proteins - immunology | Octamer Transcription Factors - genetics | Nucleotidyltransferases - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Signal Transduction | Membrane Proteins - genetics | RNA-Binding Proteins - immunology | PTB-Associated Splicing Factor - metabolism | Nuclear Matrix-Associated Proteins - metabolism | PTB-Associated Splicing Factor - immunology | DNA - metabolism | Host-Pathogen Interactions | Nuclear Matrix-Associated Proteins - genetics | HeLa Cells | RNA-Binding Proteins - metabolism | Calcium-Binding Proteins - genetics | RNA-Binding Proteins - genetics | Multiprotein Complexes | Human Umbilical Vein Endothelial Cells - immunology | Intracellular Signaling Peptides and Proteins - immunology | Human Umbilical Vein Endothelial Cells - virology | Interferon Regulatory Factor-3 - genetics | Ku Autoantigen - genetics | Transfection | HEK293 Cells | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Octamer Transcription Factors - metabolism | Interferon Regulatory Factor-3 - immunology | Calcium-Binding Proteins - metabolism | DNA - immunology | Nuclear Matrix-Associated Proteins - immunology | Ku Autoantigen - immunology | Membrane Proteins - immunology | Nuclear Proteins - metabolism | Ku Autoantigen - metabolism | RNA, Long Noncoding - genetics | Immunity, Innate | Nuclear Proteins - immunology | DNA - genetics | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein Binding | Nucleotidyltransferases - immunology | RNA, Long Noncoding - metabolism | RNA sequencing | Immune response | RNA | DNA | Genetic research | Interferon | Biological response modifiers | Mass spectrometry | Index Medicus | Human Umbilical Vein Endothelial Cells | Nuclear Matrix-Associated Proteins | Herpesvirus 8, Human | RNA-Binding Proteins | Life Sciences | Interferon Regulatory Factor-3 | Genetics | Calcium-Binding Proteins | Intracellular Signaling Peptides and Proteins | PTB-Associated Splicing Factor | Nuclear Proteins | Membrane Proteins | Nucleotidyltransferases | Ku Autoantigen | Octamer Transcription Factors | RNA, Long Noncoding
Journal Article
Journal Article
Immunologic Research, ISSN 0257-277X, 04/2017, Volume 65, Issue 2, pp. 564 - 571
Etiology, pathogenesis, and immunology of systemic lupus erythematosus (SLE) form a complex, still undeciphered picture that recently has been further made... 
HERV | Crossreactivity | EBV | SLE | HPV | LOW-SIMILARITY | AUTOANTIGEN | IMMUNOLOGY | TYROSINE-PHOSPHATASE | DEFICIENCY | ENDOGENOUS RETROVIRUSES | FUNCTIONAL VARIANT | MOLECULAR MIMICRY | ASSOCIATION | EXPRESSION | EPSTEIN-BARR-VIRUS | Autoimmunity | Epitope Mapping | Humans | Antigens, CD19 - genetics | Antibodies, Viral - blood | Receptors, Natural Killer Cell - immunology | Ku Autoantigen - genetics | Papillomaviridae - immunology | Peptide Fragments - immunology | Lupus Erythematosus, Systemic - immunology | Capsid Proteins - immunology | Papillomavirus Infections - immunology | Oncogene Proteins, Viral - genetics | Papillomavirus Infections - virology | Peptide Fragments - genetics | Antigens, CD19 - immunology | Oncogene Proteins, Viral - metabolism | Peptide Fragments - metabolism | Complement C4 - metabolism | Capsid Proteins - metabolism | Lupus Erythematosus, Systemic - virology | Receptors, Natural Killer Cell - metabolism | Ku Autoantigen - immunology | Ku Autoantigen - metabolism | Complement C4 - immunology | Complement C4 - genetics | Cross Reactions | Papillomavirus Vaccines - immunology | Antigens, CD19 - metabolism | Oncogene Proteins, Viral - immunology | Capsid Proteins - genetics | Receptors, Natural Killer Cell - genetics | Proteins | Lupus | Antigens | Killer cells | Systemic lupus erythematosus | Analysis | Transplantation of organs, tissues, etc | Development and progression | Health aspects | Papillomavirus infections | Human papillomavirus | Hypotheses | Immune response | Immunology | Peptides | Autoimmune diseases | Index Medicus
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 12/2015, Volume 67, Issue 12, pp. 3234 - 3244
Objective. To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their clinical associations, in a... 
ANTIBODIES | ANTRAL VASCULAR ECTASIA | SUBSETS | CLASSIFICATION | PREVALENCE | RHEUMATOLOGY | JAPANESE PATIENTS | FRENCH | RNA-POLYMERASE-III | CLINICAL-SIGNIFICANCE | FEATURES | Receptors, Platelet-Derived Growth Factor - immunology | Gastric Antral Vascular Ectasia - immunology | Humans | Middle Aged | Centromere Protein B - immunology | Immunoblotting | Male | Raynaud Disease - etiology | DNA Topoisomerases, Type I - immunology | Esophageal Motility Disorders - etiology | Centromere Protein A | Scleroderma, Systemic - complications | Ribonucleoproteins - immunology | Female | Contracture - immunology | Gastric Antral Vascular Ectasia - etiology | Telangiectasis - immunology | Principal Component Analysis | DNA-Binding Proteins - immunology | Exoribonucleases - immunology | RNA-Binding Proteins - immunology | Scleroderma, Systemic - immunology | RNA Polymerase III - immunology | Scleroderma, Systemic - epidemiology | Chromosomal Proteins, Non-Histone - immunology | Autoantibodies - immunology | Ku Autoantigen | Telangiectasis - etiology | Smoking - epidemiology | Autoantigens - immunology | Sex Factors | Aged | Exosome Multienzyme Ribonuclease Complex - immunology | Pol1 Transcription Initiation Complex Proteins - immunology | Raynaud Disease - immunology | Australia | Esophageal Motility Disorders - immunology | Antigens, Nuclear - immunology | Neoplasms - epidemiology | Cohort Studies | Contracture - etiology | Principal components analysis | RNA polymerase | Autoimmune diseases | Patients | Index Medicus | Abridged Index Medicus
Journal Article
Immunology, ISSN 0019-2805, 06/2013, Volume 139, Issue 2, pp. 166 - 178
Re‐expression of recombinase activating genes ( RAG ) in mature B cells may support autoreactivity by enabling revision of the B ‐cell receptor ( BCR ). Recent... 
cells | autoimmunity | G DNA | Toll receptors | Toll‐like receptors | cell receptor | Autoimmunity | Toll-like receptors | CpG DNA | B cells | B-cell receptor | SYSTEMIC-LUPUS-ERYTHEMATOSUS | V(D)J RECOMBINATION | PERIPHERAL-BLOOD | INDUCTION | IMMUNOLOGY | RAG EXPRESSION | PLASMACYTOID DENDRITIC CELLS | RECOMBINATION-ACTIVATING GENES | REEXPRESSION | LYMPHOCYTES | Cell Nucleus - immunology | Antigens, Nuclear - metabolism | Homeodomain Proteins - metabolism | Humans | Homeodomain Proteins - immunology | Receptors, Antigen, B-Cell - metabolism | Toll-Like Receptor 9 - agonists | DNA-Binding Proteins - metabolism | Toll-Like Receptor 9 - immunology | Signal Transduction - immunology | Cell Nucleus - metabolism | Flow Cytometry | Phosphorothioate Oligonucleotides - pharmacology | Interleukin-6 - metabolism | B-Lymphocytes - metabolism | Immunoglobulin lambda-Chains - immunology | DNA-Binding Proteins - immunology | Oligodeoxyribonucleotides - immunology | Cells, Cultured | Phosphorothioate Oligonucleotides - immunology | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Homeodomain Proteins - genetics | Receptors, Antigen, B-Cell - immunology | B-Lymphocytes - drug effects | Immunoglobulin lambda-Chains - metabolism | Antigens, Nuclear - genetics | B-Lymphocytes - immunology | Ku Autoantigen | Signal Transduction - drug effects | Autoantigens - immunology | Interleukin-6 - immunology | Oligodeoxyribonucleotides - pharmacology | Antigens, Nuclear - immunology | Microscopy, Fluorescence | Autoantigens | Immunoglobulins | Oligodeoxynucleotides | T cell receptors | Immune system | Index Medicus | Original
Journal Article
Journal Article
Journal Article