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Nature (London), ISSN 1476-4687, 2015, Volume 527, Issue 7578, pp. 329 - 335
.... Here we demonstrate that exosomes from mouse and human lung-, liver-and brain-tropic tumour cells fuse preferentially with resident cells at their predicted destination, namely lung fibroblasts... 
CELLS | BONE METASTASES | VESICLES | BREAST-CANCER METASTASIS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GROWTH | NICHE | MICROVESICLES | PROTEINS | PROTEOMICS | Exosomes - metabolism | Tropism | Phosphorylation | Epithelial Cells - metabolism | Receptors, Vitronectin - antagonists & inhibitors | Humans | Lung - cytology | Integrin beta4 - metabolism | Integrins - metabolism | Brain - metabolism | Integrin alpha6beta1 - metabolism | S100 Proteins - genetics | Neoplasm Metastasis - prevention & control | Female | Kupffer Cells - metabolism | Lung - metabolism | Receptors, Vitronectin - metabolism | Epithelial Cells - cytology | Integrin alpha6beta4 - metabolism | Fibroblasts - metabolism | Biomarkers - metabolism | Brain - cytology | Kupffer Cells - cytology | Endothelial Cells - metabolism | Liver - metabolism | Mice, Inbred C57BL | Integrin alpha6beta4 - antagonists & inhibitors | Organ Specificity | Animals | Endothelial Cells - cytology | Neoplasm Metastasis - pathology | Cell Line, Tumor | Integrin beta Chains - metabolism | Fibroblasts - cytology | Liver - cytology | Mice | Genes, src | Integrins - antagonists & inhibitors | Complications and side effects | Development and progression | Cell organelles | Metastasis | Health aspects | Integrins | Tumors | Studies | Microscopy | Liver | Melanoma | Fibroblasts | Breast cancer | Chemokines | mechanisms of disease | cancer microenvironment | BASIC BIOLOGICAL SCIENCES | metastasis | 60 APPLIED LIFE SCIENCES
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2012, Volume 143, Issue 3, pp. 765 - 776.e3
... IL-17RA −/− mice and of bone marrow chimeric mice devoid of IL-17 signaling in immune and Kupffer cells ( IL-17RA... 
Gastroenterology and Hepatology | Immune Response | Myofibroblast | Bone Marrow-Derived Macrophages | Mouse Model | RAT-LIVER | TARGET | IL-17 RECEPTOR | HEPATOCYTES | FAMILY-MEMBERS | STAT3 | TRANSDUCTION | PATHWAY | DISEASE | GENE-EXPRESSION | GASTROENTEROLOGY & HEPATOLOGY | Kupffer Cells - pathology | Liver - pathology | Carbon Tetrachloride | Humans | Transforming Growth Factor beta1 - metabolism | Hepatic Stellate Cells - metabolism | Receptors, Interleukin-17 - genetics | Interleukin-23 - genetics | Receptors, Interleukin-17 - deficiency | Interleukins - genetics | Liver Cirrhosis, Experimental - prevention & control | Liver - immunology | Time Factors | Bone Marrow Transplantation | Liver Cirrhosis, Alcoholic - immunology | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | Interleukin-17 - administration & dosage | Liver Cirrhosis, Experimental - immunology | Signal Transduction | Liver Cirrhosis, Alcoholic - pathology | Liver - metabolism | Interleukin-17 - genetics | Genotype | Bile Ducts - surgery | Disease Progression | Mice, Knockout | Interleukin-17 - metabolism | Phenotype | Interleukins - deficiency | Mice | Liver Cirrhosis, Experimental - metabolism | Tumor Necrosis Factor-alpha - metabolism | Inflammation Mediators - administration & dosage | Liver Cirrhosis, Experimental - etiology | Interleukin-23 - deficiency | Ligation | Hepatic Stellate Cells - immunology | Inflammation Mediators - metabolism | STAT3 Transcription Factor - deficiency | Liver Cirrhosis, Experimental - pathology | Kupffer Cells - metabolism | Hepatic Stellate Cells - pathology | Cell Line | Interleukin-1 - metabolism | Collagen Type I - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Interleukin-17 - deficiency | Liver Cirrhosis, Experimental - genetics | Animals | Interleukins - administration & dosage | Kupffer Cells - immunology | Medical colleges | Liver diseases | Liver | Carbon tetrachloride | Transforming growth factors | Muscle proteins | Macrophages | Endothelium | Messenger RNA | Interleukins | Actin | Analysis | Collagen | Fibrosis | Liver cirrhosis | Index Medicus | Abridged Index Medicus
Journal Article
Immunology, ISSN 1365-2567, 2010, Volume 129, Issue 3, pp. 363 - 374
...‐parenchymal liver cells (NPC) as a major component of the innate and adaptive immune system of the liver... 
sinusoidal endothelial cells | Toll‐like receptor | innate immunity | Kupffer cells | Innate immunity | Sinusoidal endothelial cells | Toll-like receptor | TOLERANCE | TRAUMA-HEMORRHAGE | IMMUNOLOGY | REPLICATION | HEPATITIS-C VIRUS | SINUSOIDAL ENDOTHELIAL-CELLS | LIPOPOLYSACCHARIDE | MICE | UP-REGULATION | T-CELLS | Tumor Necrosis Factor-alpha - metabolism | Interferon-alpha - pharmacology | Interferon-beta - immunology | Gene Expression - genetics | Dendritic Cells - immunology | Culture Media, Conditioned - pharmacology | Antigens, CD - metabolism | CD4-Positive T-Lymphocytes - immunology | Histocompatibility Antigens Class I - metabolism | Liver - immunology | Lymphocyte Activation - immunology | Gene Expression - immunology | Antibodies - immunology | Toll-Like Receptor 4 - agonists | Dendritic Cells - drug effects | Histocompatibility Antigens Class II - metabolism | Kupffer Cells - metabolism | Toll-Like Receptor 3 - genetics | Toll-Like Receptors - metabolism | Interleukin-6 - metabolism | Dendritic Cells - metabolism | Interferon-alpha - metabolism | Virus Replication - drug effects | Poly I-C - pharmacology | Endothelial Cells - metabolism | Mice, Inbred C57BL | Toll-Like Receptor 4 - genetics | Virus Replication - immunology | Toll-Like Receptor 3 - agonists | Encephalomyocarditis virus - immunology | Toll-Like Receptor 3 - metabolism | Toll-Like Receptor 4 - metabolism | Toll-Like Receptors - agonists | Interferon-alpha - immunology | Kupffer Cells - drug effects | Antibodies - pharmacology | Endothelial Cells - immunology | Immunity, Innate - immunology | Animals | Interferon-beta - metabolism | Interferon-beta - pharmacology | Toll-Like Receptors - genetics | T-Lymphocytes - immunology | Liver - cytology | Mice | CD8-Positive T-Lymphocytes - immunology | Endothelial Cells - drug effects | Kupffer Cells - immunology | Medical colleges | Immune response | Dendritic cells | Interferon beta | Cross infection | Nosocomial infections | Biological response modifiers | T cells | Endothelium | Antigens | Ligands | T cell receptors | Immune system | Original
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 8, p. e105429
...(+) immature myeloid cells in peripheral blood. ECFP was also detected in the large majority... 
FACTOR-I CSF-1 | FACTOR-1 RECEPTOR | ISOLATED LYMPHOID FOLLICLES | COLONY-STIMULATING FACTOR | DIFFERENTIAL TRANSCRIPTION | IMMUNOHISTOCHEMICAL LOCALIZATION | MULTIDISCIPLINARY SCIENCES | HEMATOPOIETIC STEM-CELLS | INTESTINAL LAMINA PROPRIA | MONONUCLEAR PHAGOCYTE SYSTEM | T-CELLS | Biomarkers - metabolism | Microglia - metabolism | Peyer's Patches - metabolism | Liver - metabolism | Transgenes - genetics | Mice, Transgenic - genetics | Receptor, Macrophage Colony-Stimulating Factor - genetics | Male | Monocytes - metabolism | Green Fluorescent Proteins - genetics | Intestines - metabolism | Macrophage Colony-Stimulating Factor - metabolism | Cell Differentiation - genetics | Kidney - metabolism | Animals | Spleen - metabolism | Yolk Sac - metabolism | Trans-Activators - genetics | Female | Kupffer Cells - metabolism | Mice | Langerhans Cells - drug effects | Langerhans Cells - metabolism | Protection and preservation | Embryonic development | Genetic engineering | Dendritic cells | Macrophages | Liver | Immunohistochemistry | Transcription | Laboratories | Kupffer cells | Differentiation (biology) | Infections | Gene deletion | Kinases | Follicles | Blood | Proteins | Biomedical materials | Clonal deletion | Lymphocytes | Peripheral blood | Biocompatibility | Digestive tract | VP16 protein | Yolk | Spleen | Peyer's patches | Medical research | Myeloid cells | Kidneys | Digestive system | Transgenic mice | Lamina propria | Inflammation | Cell differentiation | Embryos | Microglia | Yolk sac | Monocytes | Hepatocytes | Lungs | Stem cells | Langerhans cells | Adults | Infiltration | Dendritic structure
Journal Article
Nature medicine, ISSN 1546-170X, 2016, Volume 22, Issue 8, pp. 945 - 951
Journal Article
Hepatology (Baltimore, Md.), ISSN 1527-3350, 2008, Volume 48, Issue 3, pp. 978 - 990
Journal Article
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 4383 - 21
Journal Article
PloS one, ISSN 1932-6203, 2018, Volume 13, Issue 7, p. e0200847
...) in vitro, we used multicellular 3D human liver organoids developed in our laboratory. These organoids consist of primary human hepatocytes, Kupffer cells, quiescent stellate cells and liver sinusoidal endothelial cells... 
OVEREXPRESSION | HOMEOSTASIS | LIPID-METABOLISM | MULTIDISCIPLINARY SCIENCES | DISEASE | SENSITIVITY | SYSTEMS | LIPOPROTEIN-LIPASE | Glucose Transporter Type 4 - metabolism | Signal Transduction | Humans | Liver - metabolism | Organoids - cytology | MicroRNAs - metabolism | Necrosis - metabolism | Non-alcoholic Fatty Liver Disease - metabolism | Hepatocytes - metabolism | Insulin Receptor Substrate Proteins - metabolism | Inflammation - metabolism | Insulin - metabolism | Matrix Metalloproteinase 9 - metabolism | Matrix Metalloproteinase 8 - metabolism | Organoids - metabolism | Chemokine CCL3 - metabolism | Chemokine CCL2 - metabolism | Kupffer Cells - metabolism | Liver - cytology | Interleukin-6 - metabolism | Care and treatment | MicroRNA | Liver diseases | Development and progression | Insulin resistance | Inflammation | Research | Laboratories | Liver | Kupffer cells | Fluorescence | Lipids | Interleukin 6 | Liver cancer | Fatty liver | Organoids | Rodents | Gastroenterology | Drug metabolism | Lipoprotein (low density) receptors | Inhibition | Lipid metabolism | Stellate cells | Cytokines | Incubation | Internal medicine | CCL3 protein | Regression analysis | Gene expression | Metabolism | Ribonucleic acid--RNA | Insulin | Patients | Fatty acids | Endothelial cells | Gelatinase B | Steatosis | Medicine | Urea | Signaling | Hepatocytes | Tumor necrosis factor | Pharmacy | Fibrosis | Neutrophil collagenase | Diabetes | Chemokines | Monocyte chemoattractant protein 1 | Metabolic disorders | RNA | Ribonucleic acid
Journal Article