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Journal of Neurochemistry, ISSN 0022-3042, 10/2016, Volume 139, Issue S1, pp. 156 - 178
Dopamine‐releasing neurons within the Substantia nigra (SN DA) are particularly vulnerable to degeneration compared to other dopaminergic neurons. The... 
D2‐autoreceptor‐coupled GIRK2 channels | Cav1.3 L‐type/Cav3.1 T‐type calcium channels | neuronal calcium sensor NCS‐1 | ambroxol | A‐type Kv4.3/KChip3 potassium channels | Kir6.2/SUR1 potassium channels | Cav1.3 L-type/Cav3.1 T-type calcium channels | neuronal calcium sensor NCS-1 | A-type Kv4.3/KChip3 potassium channels | D2-autoreceptor-coupled GIRK2 channels | SENSITIVE POTASSIUM CHANNELS | Kir6 | Cav3 | OXIDANT STRESS | Cav1 | K-ATP CHANNELS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CA2+ CHANNELS | A-type Kv4 | GLUCOCEREBROSIDASE MUTATIONS | NEUROSCIENCES | KChip3 potassium channels | 3L-type | D2-AUTORECEPTOR RESPONSES | ALPHA-SYNUCLEIN FORM | SUR1 potassium channels | LOCUS-COERULEUS | MPTP MOUSE MODEL | MITOCHONDRIAL-DNA DELETIONS | 1 T-type calcium channels | Stress, Physiological - physiology | Parkinson Disease - pathology | Animals | Calcium - physiology | Substantia Nigra - pathology | Dopaminergic Neurons - pathology | Dopaminergic Neurons - metabolism | Humans | Ion Channels - physiology | Parkinson Disease - metabolism | Substantia Nigra - metabolism | Health Status | Calcium channels | Stress (Physiology) | Parkinson's disease | Potassium channels | Neurons | Dopamine | Calcium | Animal behavior | Rodents | Bandwidths | Parkinsons disease | Homeostasis | Physiology | Metabolism | Kir6.2 | Cav3.1 T‐type calcium channels | Cav1.3 L‐type | Jörg B. Schulz and John Hardy | Review | Parkinson Disease. Guest Editors | A‐type Kv4.3
Journal Article
FEBS Letters, ISSN 0014-5793, 12/2015, Volume 589, Issue 24, pp. 3760 - 3772
Glial cell line-derived neurotrophic factor (GDNF) and its canonical receptor Ret can signal together or independently to fulfill many important functions in... 
Rearranged during transfection | Parkinson disease | Drug addiction | Mouse model | Dopaminergic system | Glia cell line-derived neurotrophic factor | MAOA/MAOB | orphan nuclear receptor and transcription factor | cytoplasmic SH2 domain containing protein tyrosine phosphatase | Ras | RRF | COMT | PTEN-induced putative kinase 1 | SH3 and multiple ankyrin repeat domains 3, proline-rich synapse-associated protein 2 (ProSAP2) | PI3K | sorting protein-related receptor with A-type repeats, a member of the mammal Vps10p domain receptor | subunits of the Ca2+-sensitive, voltage gated A-type K+ channel | SH2 domain containing transforming protein 1 | Nurr1 | proprotein convertases | protein kinase B, serine/threonine-specific protein kinase | calcium-calmodulin-dependent protein kinase II β isoform | FRS2 | phosphatase and tensin homolog | catecholamine | SHP-2 | growth factor receptor-bound protein 2, 7 and 10, adaptor proteins | fibroblast growth factor receptor substrate 2, adaptor protein | monoamine oxidases A and B | carbonyl cyanide m-chlorophenyl hydrazone | ERK | brain derived neurotrophic factor | deglycase, oxidative stress sensor and redox-sensitive chaperone and protease | VTA | tyrosines, which can be phosphorylated | cAMP | extracellular-signal-regulated kinases, classical MAPKs | CaMKIIβ | Kv4.3 and KChip3 | GRB2/7/10 | Ser/Thr | SNP | endoplasmatic reticulum | nerve growth factor | monoamine, neurotransmitter type including dopamine, epinephrine (adrenaline) and norepinephrine (noradrenaline) | TGF-β | Akt, PKB | phospholipase γ cleaves the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2) into diacyl glycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) ppp3R1/ppp3CB, calcineurin subunits | PC5A, PC5B, and PC7 | EGR1 | proprotein convertase subtilisin/kexin type 6 | substantia nigra | phosphotyrosine-interaction domain | BDNF | adaptor protein of the PDZ-LIM family | γ-aminobutyric acid, inhibitory neurotransmitter in mammalian central nervous system | Tyr | FosB/ΔFosB | IRS1/2 | LIM | dopamine transporter | enhanced green fluorescent protein | GDNF | DAT | SOS | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | retro-rubal field | transforming growth factor β is a secreted protein that controls proliferation and cellular differentiation | MPTP | GTPase | hypoxia-inducible factor-1alpha | GDNF family of ligands | Ret | GPI | Shank3 | NCAM | Enigma | JNK | (rearranged during transfection) canonical GDNF receptor, a receptor tyrosine kinase | PTEN | 6-OHDA | DJ-1 | (rapidly accelerated fibrosarcoma/rat fibrosarcoma) family of serine/threonine-protein kinase | SHC | NF-κB | (acronym combining the first letters of three proteins – post synaptic density protein (PSD95), Drosophila disc large tumor suppressor (Dlg1), and zonula occludens-1 protein (zo-1) that have this common domain) protein interaction domain | phosphotyrosine-binding domains | insulin receptor substrate 1, adaptor protein, contains a PTB and PH domain | Rac1 | GFRα | nuclear factor ‘kappa-light-chain-enhancer’ of activated B-cells, transcription factor family with Rel homology domain (RHD) | catechol-O-methyltransferase | early growth response protein 1, Zif268 (zinc finger protein 225), NGFI-A (nerve growth factor-induced protein A), is a zinc finger transcription factor | serine and threonine, which can be phosphorylated | GDNF family receptor α | PKA | protein kinase A, a family of cAMP-dependent protein kinase | MAPK | NGF | SorLA | ventral tegmental area | son of sevenless, family of guanine nucleotide exchange factors that act on Ras | GABA | HIF-1a | Ras-related C3 botulinum toxin substrate 1 (Rho family), a small GTPase, like CDC42 | GAP1/2 | PTB | (Rat sarcoma) family of small membrane-associated GTPase | cycles between an active GTP-bound and an inactive GDP-bound state | glycogen synthase kinase 3β | Src | glia cell line-derived neurotrophic factor | PACE4, PCSK6 | pleckstrin homology domain | co-repressor for element-1-silencing transcription factor, a chromatin-modifying corepressor complex that acts with REST (repressor for element-1 silencing transcription factor) complex | c-Jun N-terminal kinases, members of the MAPK family of proteins | EGFP | cell division control protein 42 homolog, a plasma membrane-associated small GTPase of the Rho family | (acronym combining the first letters of three proteins – Lin11, Isl-1 and Mec-3 – that have this common domain) protein interaction domain of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker | CCCP | (sarcoma protein) membrane-associated tyrosine kinase with different Src homology (SH) domains characteristic for all 9 members of the Src family kinases | DOK1/4/5/6 | (Ras homolog) family of small GTPases including Cdc42, Rac1, and RhoA | single-nucleotide polymorphism analysis | VPS10P | Rho | MEN2B | phosphatidylinositol-4,5-bisphosphate 3-kinase | 6-hydroxy-dopamine | mitogen-activated protein kinase, can phosphorylate serine, threonine, and tyrosine, e.g. p38MAPK | Cdc42 | docking proteins, have a PH and SH3 domain | GFLs | PDZ | vacuolar protein sorting 10 protein-domain receptors are type 1 transmembrane proteins | PLCγ | GTPase-activating proteins 1 and 2 | 3′,5′-cyclic adenosine monophosphate | neuronal cell adhesion molecule | TIEG | TGF-β-inducible early-response gene, a zinc finger transcription factor Vav2, adaptor protein and guanine nucleotide exchange factor for the Rho family of Ras-related GTPases | PINK1 | Raf | CoREST | multiple endocrine neoplasia 2 type B, mutation in the kinase domain of the Ret leading to constitutive active receptor | dopaminergic | glycosylphosphatidylinositol | FBJ murine osteosarcoma viral oncogene homolog B, a transcription factor with a truncated Δ form | gsk3β | ENTERIC NERVOUS-SYSTEM | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUBSTANTIA-NIGRA | CELL BIOLOGY | MICE LACKING GDNF | C-RET | BIOPHYSICS | NEUROTROPHIC FACTOR PROMOTES | MULTIPLE ENDOCRINE NEOPLASIA | SURVIVAL IN-VIVO | RECEPTOR TYROSINE KINASE | CELL-LINE | EARLY-ONSET PARKINSONISM | Glial Cell Line-Derived Neurotrophic Factor - physiology | Parkinson Disease - pathology | Animals | Proto-Oncogene Proteins c-ret - physiology | Dopamine - physiology | Mesencephalon - metabolism | Humans | Dopaminergic Neurons - physiology | Parkinson Disease - metabolism | Synaptic Transmission | Mesencephalon - pathology | Physiological aspects | Neurons | Parkinson's disease
Journal Article
Journal of Comparative Neurology, ISSN 0021-9967, 03/2016, Volume 524, Issue 4, pp. 846 - 873
Subthreshold A‐type K+ currents (ISAs) have been recorded from the somata of nociceptors and spinal lamina II excitatory interneurons, which sense and modulate... 
KChIP2 | DPP10 | RRID:AB_236936 | RRID:AB_476826 | KChIP1 | RRID:AB_2314158 | RRID:AB_10673162 | RRID:AB_634520 | RRID:AB_845371 | RRID:AB_10000342 | KChIP3 | RRID:AB_2314535 | RRID:AB_887824 | RRID:AB_2313848 | RRID:AB_2255737 | RRID:AB_2336928 | DPP6 | Kv4.3 | Kv4.2 | RRID:AB_2156525 | spinal cord | RRID:RGD_70508 | RRID:AB_2313584 | RRID:AB_2130257 | RRID:AB_10015282 | RRID:AB_2079751 | RRID:AB_2280942 | RRID:AB_2491074 | RRID:AB_2336930 | RRID:AB_2336931 | RRID:AB_2336932 | RRID:AB_2314723 | RRID:AB_2336933 | RRID:AB_2336934 | RRID:AB_2340472 | RRID:AB_2336935 | RRID:AB_1840999 | RRID:AB_632234 | RRID:AB_476854 | RRID:AB_1080976 | RRID:AB_2278725 | DRG | RRID:AB_2315294 | RRID:AB_2372612 | Spinal cord | RRID: AB_ 2255737 | RAT | RRID: AB_ 476854 | RRID: AB_ 10015282 | RRID: AB_ 10000342 | RRID: AB_ 1840999 | RRID: AB_ 236936 | RRID: AB_ 2314158 | RRID: AB_ 2280942 | RRID: AB_ 2313584 | RRID: AB_ 2336934 | RRID: AB_ 2278725 | RRID: AB_ 2336933 | RRID: AB_ 2336932 | RRID: AB_ 2336931 | RRID: AB_ 887824 | RRID: AB_ 2314723 | RRID: AB_ 2336935 | RRID: RGD_ 70508 | RRID: AB_ 2491074 | EXCITATORY INTERNEURONS | RRID: AB_ 634520 | RRID: AB_ 2340472 | RRID: AB_ 2315294 | RRID: AB_ 2336930 | ALPHA-SUBUNITS | RRID: AB_ 2313848 | RRID: AB_ 2314535 | RRID: AB_ 2336928 | RRID: AB_ 1080976 | DORSAL-HORN | RRID: AB_ 2156525 | RRID: AB_ 2130257 | ZOOLOGY | PRIMARY SENSORY NEURONS | RRID: AB_ 2079751 | K+ CHANNELS | IMMUNOHISTOCHEMICAL LOCALIZATION | DOWN-REGULATION | RRID: AB_ 476826 | NEUROSCIENCES | RRID: AB_ 10673162 | RRID: AB_ 2372612 | RRID: AB_ 632234 | LAMINA-II | EXPRESSION | RRID: AB_ 845371 | Immunohistochemistry | Spinal Cord - metabolism | Cell Count | Cells, Cultured | Cell Size | Cytoplasm - metabolism | Male | Ganglia, Spinal - cytology | Nociceptors - cytology | Kv Channel-Interacting Proteins - metabolism | Rats, Sprague-Dawley | Blotting, Western | Microscopy, Confocal | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - metabolism | Shal Potassium Channels - metabolism | Animals | Interneurons - metabolism | Cell Membrane - metabolism | Nociceptors - metabolism | Lumbar Vertebrae | Spinal Cord - cytology | Ganglia, Spinal - metabolism | Proteins | Potassium channels
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 09/2019, Volume 20, Issue 17, p. 4073
A-type K+ channels contribute to regulating the propagation and frequency of action potentials in smooth muscle cells (SMCs). The present study (i) identified... 
CELLS | vas deferens | POTASSIUM CURRENTS | A-type K+ channel | testosterone | castration | KV4.3 | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | smooth muscle | SUBUNITS | CHEMISTRY, MULTIDISCIPLINARY | K(V)4 | CALCIUM | GENE-EXPRESSION | MOLECULAR-CLONING | MODULATION
Journal Article