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British Journal of Pharmacology, ISSN 0007-1188, 01/2010, Volume 159, Issue 1, pp. 93 - 101
Introduction:  Doxorubicin, an anthracycline widely used in the treatment of a broad range of tumours, causes acute QT prolongation. Dexrazoxane has been shown... 
IKs | QT interval | IKr | dexrazoxane | hERG | KvLQT1/MinK | ICHS7B guideline | isolated guinea‐pig heart | doxorubicin | moxifloxacin | HERG | Dexrazoxane | Isolated guinea-pig heart | Moxifloxacin | Doxorubicin | isolated guinea-pig heart | KvLQT1 | Themed Section | MinK | I Ks | I Kr
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2017, Volume 114, Issue 32, pp. E6686 - E6694
IKs channels open in response to depolarization of the membrane voltage during the cardiac action potential, passing potassium ions outward to repolarize... 
Heart | KCNE1 | minK | KvLQT1 | KCNQ1 | Biological Sciences | PNAS Plus | heart
Journal Article
European heart journal, ISSN 0195-668X, 2012, Volume 33, Issue 6, pp. 714 - 723
Heterozygous mutations in KCNQ1 cause type 1 long QT syndrome (LQT1), a disease characterized by prolonged heart rate-corrected QT interval (QTc) and... 
QTc | CARDIAC & CARDIOVASCULAR SYSTEMS | GENE | KCNQ1 | KVLQT1 | Long QT syndrome | 3 untranslated region | Single nucleotide polymorphism | MUTATIONS | MICRORNAS | SPECTRUM
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2010, Volume 363, Issue 15, pp. 1397 - 1409
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 04/2014, Volume 111, Issue 14, pp. E1438 - E1446
KCNE1 (E1) β-subunits assemble with KCNQ1 (Q1) voltage-gated K(+) channel α-subunits to form IKslow (IKs) channels in the heart and ear. The number of E1... 
MinK | KVLQT1 | KV7.1 | LQTS | Single-particle fluorimetry | Animals | Potassium Channels, Voltage-Gated - physiology | Spectrum Analysis - methods | Humans | Photochemistry | Biological Sciences | PNAS Plus | minK | single-particle fluorimetry
Journal Article
Nature Genetics, ISSN 1061-4036, 09/2008, Volume 40, Issue 9, pp. 1092 - 1097
Journal Article
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 10/2019, Volume 33, Issue 10, pp. 11349 - 11363
Herbs have a long history of use as folk medicine anticonvulsants, yet the underlying mechanisms often remain unknown. Neuronal voltage-gated potassium channel... 
epilepsy | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUBUNITS | CELL BIOLOGY | JERVELL | KCNQ1 | KVLQT1 | KCNQ2 | MUTATION | BIOLOGY | KCNQ3 | KCNQ5 | COMPONENT | RETIGABINE | herbal medicine | EXPRESSION | K(V)7 K+ CHANNEL | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2014, Volume 111, Issue 50, pp. E5383 - E5392
Journal Article
Circulation, ISSN 0009-7322, 2012, Volume 125, Issue 16, pp. 1988 - +
Journal Article
Journal Article
ELIFE, ISSN 2050-084X, 01/2016, Volume 5
Cardiac repolarization is determined in part by the slow delayed rectifier current (I-Ks), through the tetrameric voltage-gated ion channel, KCNQ1, and its... 
SLOW ACTIVATION | KVLQT1 | BIOLOGY | LONG-QT SYNDROME | SITE-SPECIFIC INCORPORATION | KCNE BETA-SUBUNITS | PROTEINS | MAMMALIAN-CELLS | MINK | POTASSIUM CHANNEL | ACCESSORY SUBUNITS
Journal Article
JOURNAL OF GENERAL PHYSIOLOGY, ISSN 0022-1295, 03/2015, Volume 145, Issue 3, pp. 201 - 212
K(v)7.1 voltage-gated K+ ( K-v) channels are present in the apical membranes of marginal cells of the stria vascularis of the inner ear, where they mediate K+... 
PHYSIOLOGY | INNER-EAR | HERG | GENE | KCNQ1 | KVLQT1 | INBRED STRAINS | VESTIBULAR DARK CELLS | MUTATIONS | STRIA VASCULARIS | K+ SECRETION
Journal Article
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