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Molecules, ISSN 1420-3049, 09/2019, Volume 24, Issue 19, p. 3502
Kynurenic acid (KYNA), a metabolite of tryptophan, as an excitatory amino acid receptor antagonist is an effective neuroprotective agent in case of... 
excitatory amino acid receptors | kynurenic acid | Mannich reaction | neuroprotection
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 01/2018, Volume 59, Issue 2, pp. 163 - 166
A short and efficient synthesis of novel tetracyclic Kynurenic acid analogues, isolated from chestnut honey, is described. The crucial step of the strategy was... 
Kynurenic acid analogues | Chestnut honey | Microwave assisted synthesis | Natural products | WINTERFELDT-OXIDATION | CHEMISTRY, ORGANIC | LACTAMS | INDOLE-DERIVATIVES | PYRROLIZIDINES | ALKALOIDS | Quinoline | Honey | Synthesis | Organic acids | Organic compounds
Journal Article
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 06/2019, Volume 10, p. 1406
Purpose: The investigation of anti-inflammatory and immunosuppressive functions of Kynurenic acid (KYNA) is now in focus. There is also substantial evidence... 
PROTEIN TSG-6 | CELLS | LUNG | Chlamydia pneumoniae | TNF-alpha | U-937 | TSG-6 | MICE | IMMUNOLOGY | kynurenic acid | Staphylococcus | BRAIN | TNF-α
Journal Article
Journal Article
Journal of Neural Transmission, ISSN 0300-9564, 1/2017, Volume 124, Issue 1, pp. 99 - 112
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2011, Volume 667, Issue 1, pp. 182 - 187
Journal Article
Drug Design, Development and Therapy, ISSN 1177-8881, 2017, Volume 11, pp. 27 - 34
Background: The complex pathophysiology of migraine is not yet clearly understood; therefore, experimental models are essential for the investigation of the... 
Kynurenic acid analogues | Sumatriptan | Cortical spreading depression | Migraine | Nitroglycerin | MIGRAINE PROPHYLAXIS | CHEMISTRY, MEDICINAL | migraine | C-FOS IMMUNOREACTIVITY | RAT | STIMULATION-INDUCED INCREASE | NITRIC-OXIDE RELEASE | BLOOD-FLOW | SYSTEMIC NITROGLYCERIN | ANESTHETIZED CAT | nitroglycerin | DURA-MATER | CAUDAL TRIGEMINAL NUCLEUS | PHARMACOLOGY & PHARMACY | cortical spreading depression | kynurenic acid analogues | sumatriptan | Vasodilator Agents - pharmacology | Humans | Injections, Intraperitoneal | Sumatriptan - administration & dosage | Migraine Disorders - drug therapy | Nitroglycerin - pharmacology | Cortical Spreading Depression - drug effects | Dose-Response Relationship, Drug | Sumatriptan - pharmacology | Nitroglycerin - administration & dosage | Kynurenic Acid - pharmacology | Kynurenic Acid - administration & dosage | Vasodilator Agents - administration & dosage | Psychological aspects | Dosage and administration | Drug therapy | Headache | Propagation | Identification methods | Cortex | Data processing | Pharmacology | Drug screening | Neuromodulation | Potassium chloride | Investigations | Wave propagation | Acids | Experimental design | Chlorides | Spreading | Comparative studies | In vivo methods and tests | Kynurenic acid | Drugs | Neurosciences | Neuropathology | Headaches | Pain | Stroke | Studies | Brain research | Nitric oxide | Laboratory animals | Design of experiments
Journal Article
Pharmacological Reports, ISSN 1734-1140, 12/2015, Volume 67, Issue 6, pp. 1188 - 1192
Journal Article
Journal Article
Journal Article
Journal of Neural Transmission, ISSN 0300-9564, 6/2011, Volume 118, Issue 6, pp. 865 - 875
Huntington’s disease (HD) is a progressive neurodegenerative disorder, the pathomechanism of which is not yet fully understood. Excitotoxicity is known to be... 
Neurology | Neuroprotection | Neurosciences | Medicine & Public Health | Transgenic mice | N171-82Q | Huntington’s disease | Stereology | Pharmacology/Toxicology | Kynurenic acid analogue | Psychiatry
Journal Article