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Clinical and Applied Thrombosis/Hemostasis, ISSN 1076-0296, 09/2016, Volume 22, Issue 6, pp. 589 - 593
Journal Article
Production of L-asparaginase by filamentous fungi, 07/2004
L-asparaginase production was investigated in the filamentous fungi Aspergillus tamarii and Aspergillus terreus. The fungi were cultivated in medium containing... 
filamentous fungi - production of L-asparaginase - Aspergillus tamarii - Aspergillus terreus oc04105 | Tropical Diseases | Microbiology
Journal
International Journal of Biological Macromolecules, ISSN 0141-8130, 10/2019
Journal Article
Preparative Biochemistry and Biotechnology, ISSN 1082-6068, 08/2019, Volume 49, Issue 7, pp. 679 - 685
L-Asparaginase (L-ASNase) is an important enzyme used to treat acute lymphoblastic leukemia, recombinantly produced in a prokaryotic expression system.... 
Glycoswitch | His-tag | extracellular expression | L-Asparaginase
Journal Article
International Journal of Biological Macromolecules, ISSN 0141-8130, 01/2018, Volume 106, pp. 1041 - 1051
Asparaginase (EC 3.5.1.1) is an important medical enzyme that catalysis the hydrolysis of -asparagine to aspartic acid and ammonium. For over four decades .... 
l. Asparaginase | Acute lymphoblastic leukemia | Cloning
Journal Article
Cancer, ISSN 0008-543X, 01/2011, Volume 117, Issue 2, pp. 238 - 249
Journal Article
Talanta, ISSN 0039-9140, 10/2019, Volume 203, pp. 9 - 15
Biosensors are rising technologies in the pharmaceutical field for medicine discovery, development and Quality Control (QC) stages. Surface acoustic wave (SAW)... 
Method development and validation | Surface acoustic wave (SAW) biosensor | l-asparaginase
Journal Article
Aging, ISSN 1945-4589, 2016, Volume 8, Issue 9, pp. 1830 - 1831
Journal Article
Journal Article
Cell Calcium, ISSN 0143-4160, 11/2019, Volume 83, p. 102076
L-asparaginase treatment is used in the clinic to treat acute lymphoblastic leukemia (ALL) patients. Lee et al. (2019, Blood 133:2222-2232) demonstrated that... 
Huntingtin-associated protein 1 | Acute lymphoblastic leukemia | Huntingtin | L-asparaginase | IP3 receptor
Journal Article
Journal of Clinical and Diagnostic Research, ISSN 2249-782X, 04/2018, Volume 12, Issue 4, pp. XD01 - XD02
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 09/2019, Volume 9
N-15 labeled amino acids are routinely used to label proteins or nucleic acids for study by NMR. However, NMR studies of N-15 labeled amino acids in metabolite... 
L-ASPARAGINASE | THERAPY | MULTIDISCIPLINARY SCIENCES | ISOTOPE LABELING METHODS | LEUKEMIA | H-1
Journal Article
Soft Matter, ISSN 1744-683X, 2013, Volume 9, Issue 1, pp. 138 - 145
Journal Article
Annals of Oncology, ISSN 0923-7534, 06/2018, Volume 29, Issue 6, pp. 1402 - 1408
Abstract Background Arginine depletion is a putative target in hepatocellular carcinoma (HCC). HCC often lacks argininosuccinate synthetase, a citrulline to... 
ADI-PEG20 | HCC | Hepatocellular carcinoma | Argininosuccinate synthetase | ASS1 | L-ASPARAGINASE | SAFETY | PEGYLATED ARGININE DEIMINASE | PHARMACODYNAMICS | SORAFENIB | argininosuccinate synthetase | ARGININOSUCCINATE SYNTHETASE EXPRESSION | ONCOLOGY | PHARMACOKINETICS | CIRRHOSIS | ACUTE LYMPHOBLASTIC-LEUKEMIA | hepatocellular carcinoma
Journal Article
BRITISH JOURNAL OF HAEMATOLOGY, ISSN 0007-1048, 03/2019, Volume 185, pp. 44 - 44
Conference Proceeding
Journal of bioscience and bioengineering, ISSN 1389-1723, 07/2019
Directed evolution methodologies have been used as promising strategies for improving the catalytic properties of many existing enzymes. In the presented work,... 
Journal Article
01/2010
Purpose: The objective of this investigation was to isolate marine actinomycetes, screen them for L-asparaginase activity and characterise the enzyme. Methods:... 
SDS-PAGE | TGY broth | Km and Vmax | L-asparaginase | TFY broth | Solid-state media
Web Resource
Talanta, ISSN 0039-9140, 05/2018, Volume 182, pp. 83 - 91
A capillary zone electrophoresis (CZE) method with UV detection was developed for the quantification of the -asparaginase ( -ASNase) and its acidic variants.... 
Capillary zone electrophoresis | Acidic impurities | Design of experiments (DoE) | l-asparaginase
Journal Article
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