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BLOOD, ISSN 0006-4971, 06/2016, Volume 127, Issue 23, pp. 2936 - 2938
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 12/2017, Volume 60, Issue 24, pp. 10071 - 10091
Herein we report the optimization of a series of pyrrolopyrimidine inhibitors of interleukin-1 receptor associated kinase 4 (IRAK4) using X-ray crystal... 
L265P SOMATIC MUTATION | POTENT | CHEMISTRY, MEDICINAL | SERIES | PYOGENIC BACTERIAL-INFECTIONS | IBRUTINIB | HUMANS | PART 1 | PREVALENCE | IDENTIFICATION | MYD88
Journal Article
BLOOD, ISSN 0006-4971, 04/2018, Volume 131, Issue 15, pp. 1720 - 1729
The link between inflammation and cancer is particularly strong in Waldenstrom macro-globulinemia (WM), a diffuse large B-cell lymphoma wherein the majority of... 
TYROSINE KINASE | INFLAMMATION | EXOSOMES | MICROVESICLES | SOMATIC MUTATION | WALDENSTROM MACROGLOBULINEMIA | ESTABLISHMENT | HEMATOLOGY | CANCER | L265P | CELL-LINE
Journal Article
New England Journal of Medicine, ISSN 0028-4793, 04/2015, Volume 372, Issue 15, pp. 1430 - 1440
Journal Article
BLOOD, ISSN 0006-4971, 06/2016, Volume 127, Issue 22, pp. 2732 - 2741
The adaptor protein MYD88 is critical for relaying activation of Toll-like receptor signaling to NF-kappa B activation. MYD88 mutations, particularly the... 
IDENTIFIES RECURRENT MUTATIONS | ACTIVATION | GENE | CLASSIFICATION | DISORDERS | SOMATIC MUTATION | GERMINAL CENTER | WALDENSTROM MACROGLOBULINEMIA | DIFFERENTIATION | MYD88 L265P | HEMATOLOGY
Journal Article
British Journal of Haematology, ISSN 0007-1048, 03/2016, Volume 172, Issue 5, pp. 735 - 744
Journal Article
HAEMATOLOGICA, ISSN 0390-6078, 06/2018, Volume 103, Issue 6, pp. 1029 - 1037
We here describe a novel method for MYD88(L265P) mutation detection and minimal residual disease monitoring in Waldenstrom macroglobulinemia, by droplet... 
L265P SOMATIC MUTATION | MULTIPLE-MYELOMA | IGM MONOCLONAL GAMMOPATHY | LARGE B-CELL | CIRCULATING TUMOR DNA | UNDETERMINED SIGNIFICANCE | FOLLICULAR LYMPHOMA | MYD88 L265P | HEMATOLOGY | MINIMAL RESIDUAL DISEASE | CLINICAL-SIGNIFICANCE
Journal Article
Journal Article
Retina (Philadelphia, Pa.), ISSN 0275-004X, 04/2019, Volume 39, Issue 4, pp. 679 - 684
To detect the presence of MYD88 L265P mutation in the aqueous humor of patients with cytologically proven vitreoretinal lymphoma. Eight consecutive patients... 
anterior chamber paracentesis | DIAGNOSIS | MYD88 L265P mutation | vitreoretinal lymphoma | OPHTHALMOLOGY | INTRAOCULAR LYMPHOMA | SOMATIC MUTATION | aqueous humor | primary central nervous system lymphoma | NERVOUS-SYSTEM LYMPHOMA
Journal Article
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 09/2017, Volume 214, Issue 9, pp. 2759 - 2776
CD79B and MYD88 mutations are frequently and simultaneously detected in B cell malignancies. It is not known if these mutations cooperate or how crosstalk... 
MEDICINE, RESEARCH & EXPERIMENTAL | B-CELL LYMPHOMA | IN-VIVO | CHRONIC LYMPHOCYTIC-LEUKEMIA | SOMATIC MUTATION | WALDENSTROM MACROGLOBULINEMIA | IMMUNOLOGY | MYD88 L265P | NF-KAPPA-B | ANTIGEN RECEPTOR | AUTOIMMUNE-DISEASE | LYN KINASE
Journal Article
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, ISSN 0732-183X, 06/2019, Volume 37, Issue 16, pp. 1403 - 1411
BACKGROUND Waldenstrom macroglobulinemia (WM) is preceded by asymptomatic WM (AWM), for which the risk of progression to overt disease is not well defined.... 
CONSENSUS PANEL RECOMMENDATIONS | 2ND INTERNATIONAL WORKSHOP | L265P SOMATIC MUTATION | DIAGNOSIS | ONCOLOGY | DETERMINANTS | DISORDERS | CXCR4 | MONOCLONAL GAMMOPATHY | MYD88
Journal Article
by Kim, Y and Ju, H and Kim, DH and Yoo, HY and Kim, SJ and Kim, WS and Ko, YH
HUMAN PATHOLOGY, ISSN 0046-8177, 03/2014, Volume 45, Issue 3, pp. 556 - 564
Mutations in 2 upstream components of the nuclear factor kappa B (NF-kappa B) pathway, CD79B and MYD88, are important information for new target therapy in... 
CD79B | L265P SOMATIC MUTATION | WALDENSTROMS MACROGLOBULINEMIA | SUBTYPES | Diffuse large B cell lymphoma | Mutation | PATHOLOGY | NF-KAPPA-B | CANCER | MYD88 | EPSTEIN-BARR-VIRUS
Journal Article
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