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Chemistry – A European Journal, ISSN 0947-6539, 07/2015, Volume 21, Issue 28, pp. 9980 - 9983
The step‐economical late‐stage diversification of tryptophan‐containing peptides was accomplished through chemo‐ and site‐selective palladium‐catalyzed CH... 
chemoselectivity | CH activation | peptides | late‐stage derivatization | H2O | C-H activation | late-stage derivatization
Journal Article
Chemistry - A European Journal, ISSN 0947-6539, 08/2018, Volume 24, Issue 45, pp. 11559 - 11563
Trifluoromethyl-containing compounds play a significant role in medicinal chemistry, materials and fine chemistry. Although direct C-H trifluoromethylation has... 
fluorination | copper | trifluoromethylation | late-stage diversification | C−H activation
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 12/2016, Volume 138, Issue 50, pp. 16200 - 16203
Selective functionalization of ubiquitous C­(sp3)–H bonds using visible light is a highly challenging yet desirable goal in organic synthesis. The development... 
OXIDATION | AMINATION | ETHERS | DIRECT ARYLATION | AMINO-ACIDS | COMPLEXES | RADICALS | CHEMISTRY, MULTIDISCIPLINARY | C-H BONDS | LATE-STAGE FUNCTIONALIZATION | PHOTOREDOX CATALYSIS
Journal Article
ACS CATALYSIS, ISSN 2155-5435, 06/2019, Volume 9, Issue 6, pp. 4862 - 4866
Alkylated pyridines are common in pharmaceuticals, and metal catalysis is frequently used to prepare this motif via Csp(2)-Csp(3) coupling processes. We... 
REAGENTS | phosphonium salts | CHEMISTRY, PHYSICAL | late-stage | cobalt-catalysis | alkyl Negishi | DISCOVERY | pyridines | cross-coupling | C-H METHYLATION | alkylation | ARYL | LATE-STAGE FUNCTIONALIZATION
Journal Article
Effect of Tetracycline on Late-stage African trypanosomiasis in Rats, 12/2003
The effect of tetracycline on late stage African trypanosomiasis was examined in an in vivo experiment using rats infected with Trypanosoma brucei brucei   .... 
African trypanosomiasis, Tetracycline, Late Stage
Journal
Tetrahedron, ISSN 0040-4020, 11/2019, p. 130755
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 7/2016, Volume 14, Issue 28, pp. 6611 - 6637
New advances in synthetic methodologies that allow rapid access to a wide variety of functionalized heterocyclic compounds are of critical importance to the... 
BORONIC ACIDS | MEDICINAL CHEMISTRY | VISIBLE-LIGHT | DIRECT ARYLATION | ONE-POT SYNTHESIS | LIGHT PHOTOREDOX CATALYSIS | CHEMISTRY, ORGANIC | ALDEHYDE OXIDASE | C-H FUNCTIONALIZATION | LATE-STAGE FUNCTIONALIZATION | ALKYL-HALIDES
Journal Article
Chemical Society Reviews, ISSN 0306-0012, 5/2016, Volume 45, Issue 1, pp. 29 - 2936
Organic reactions that involve the direct functionalization of non-activated C-H bonds represent an attractive class of transformations which maximize atom-... 
Organic chemistry | Synthesis (chemistry) | State of the art | Oxidants | Chemical bonds | Strategy | Activation | Transformations
Journal Article
Chemical Society Reviews, ISSN 0306-0012, 05/2016, Volume 45, Issue 10, pp. 2900 - 2936
Journal Article
Chemical Reviews, ISSN 0009-2665, 07/2017, Volume 117, Issue 13, pp. 9302 - 9332
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 9/2016, Volume 14, Issue 36, pp. 8398 - 8427
Fluorination reactions of medicinal and biologically-active compounds will be discussed. Late stage fluorination strategies of medicinal targets have recently... 
MEDICINAL CHEMISTRY | REMOVABLE DIRECTING GROUPS | COPPER-MEDIATED FLUORINATION | ELECTROPHILIC FLUORINATION | C-H FLUORINATION | ENANTIOSELECTIVE FLUORINATION | REGIOSELECTIVE FLUORINATION | CHEMISTRY, ORGANIC | CONFORMATIONAL-ANALYSIS | LATE-STAGE FLUORINATION | METAL-FREE
Journal Article
Organic Letters, ISSN 1523-7060, 04/2016, Volume 18, Issue 7, pp. 1698 - 1701
The direct methylation of ortho C–H bonds in aromatic amides with dicumyl peroxide (DCP) using a nickel complex as the catalyst is reported. The reaction shows... 
DIRECTING GROUPS | FUNCTIONALIZATION | UNACTIVATED C(SP)-H BONDS | ACTIVATION | LATE-STAGE DIVERSIFICATION | ALKYLATION | ARYLATION | ARENES | CHEMISTRY, ORGANIC | C(SP)-H
Journal Article
Organic Letters, ISSN 1523-7060, 06/2018, Volume 20, Issue 11, pp. 3229 - 3232
A metal-free photoredox C–H alkylation of heteroaromatics from readily available carboxylic acids using an organic photocatalyst and hypervalent iodine... 
ORGANIC-SYNTHESIS | HETEROCYCLES | CHEMISTRY, ORGANIC | GENERATION | DERIVATIVES | LATE-STAGE FUNCTIONALIZATION | ARYLBORONIC ACIDS | N-(ACYLOXY)PHTHALIMIDES | PHOTOREDOX CATALYSIS | N-HETEROARENES | TRIFLUOROMETHYLATION
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 03/2014, Volume 136, Issue 10, pp. 3792 - 3795
On the basis of mechanism-driven reaction design, a Pd-catalyzed nucleophilic fluorination of aryl bromides and iodides has been developed. The method exhibits... 
MEDICINAL CHEMISTRY | PALLADIUM | COPPER-MEDIATED FLUORINATION | CONVERSION | CHLORIDES | LATE-STAGE FLUORINATION | CHEMISTRY, MULTIDISCIPLINARY | F-18 | PET | FLUORIDE | Communication
Journal Article
Acta Psychiatrica Scandinavica, ISSN 0001-690X, 06/2014, Volume 129, Issue 6, pp. 437 - 444
Journal Article
Chemical Society reviews, ISSN 0306-0012, 11/2016, Volume 45, Issue 22, pp. 6270 - 6288
The fluorination of organic molecules is a rapidly evolving and exciting field in synthesis, which still poses huge challenges despite the advances made in the... 
Journal Article