The New England Journal of Medicine, ISSN 0028-4793, 05/2015, Volume 372, Issue 22, pp. 2127 - 2135
About one third of the world population has latent M. tuberculosis infection. This review explains the approach to patients with latent infection, including an...
UNITED-STATES | 12-DOSE REGIMEN | IMMUNE-RESPONSE | MEDICINE, GENERAL & INTERNAL | CLINICAL-TRIAL | IMMUNODEFICIENCY-VIRUS-INFECTION | INTRAVENOUS-DRUG-USERS | ANTIRETROVIRAL THERAPY | ISONIAZID PREVENTIVE THERAPY | GAMMA RELEASE ASSAYS | PROSPECTIVE COHORT | Rifampin - analogs & derivatives | Antitubercular Agents - adverse effects | Drug Administration Schedule | Humans | Risk Factors | Latent Tuberculosis - epidemiology | Latent Tuberculosis - diagnosis | Isoniazid - administration & dosage | Latent Tuberculosis - drug therapy | Mycobacterium tuberculosis | Antitubercular Agents - administration & dosage | Latent Tuberculosis - etiology | Rifampin - administration & dosage | Drug Therapy, Combination | Practice Guidelines as Topic | Usage | Care and treatment | Tuberculin test | Tuberculosis | Diagnosis | Risk factors | Cost-benefit analysis | Latent infection | Infections | Pathogenesis | Epidemiology
UNITED-STATES | 12-DOSE REGIMEN | IMMUNE-RESPONSE | MEDICINE, GENERAL & INTERNAL | CLINICAL-TRIAL | IMMUNODEFICIENCY-VIRUS-INFECTION | INTRAVENOUS-DRUG-USERS | ANTIRETROVIRAL THERAPY | ISONIAZID PREVENTIVE THERAPY | GAMMA RELEASE ASSAYS | PROSPECTIVE COHORT | Rifampin - analogs & derivatives | Antitubercular Agents - adverse effects | Drug Administration Schedule | Humans | Risk Factors | Latent Tuberculosis - epidemiology | Latent Tuberculosis - diagnosis | Isoniazid - administration & dosage | Latent Tuberculosis - drug therapy | Mycobacterium tuberculosis | Antitubercular Agents - administration & dosage | Latent Tuberculosis - etiology | Rifampin - administration & dosage | Drug Therapy, Combination | Practice Guidelines as Topic | Usage | Care and treatment | Tuberculin test | Tuberculosis | Diagnosis | Risk factors | Cost-benefit analysis | Latent infection | Infections | Pathogenesis | Epidemiology
Journal Article
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2016, Volume 76, Issue 2, pp. 299 - 308.e16
Background Anti–tumor necrosis factor (TNF) therapy in psoriasis has been associated with an increased risk of serious infections compared with nonbiologic...
Dermatology | immunosuppressive agents | anti-inflammatory agents | anti–tumor necrosis factor | psoriasis/drug therapy | safety | biological agents | RHEUMATOID-ARTHRITIS | LATENT TUBERCULOSIS INFECTION | BIOLOGICS | DERMATOLOGY | SYSTEMIC TREATMENT | DISEASE | anti-tumor necrosis factor | ADVERSE EVENTS | Granuloma - microbiology | Severity of Illness Index | Skin Diseases, Bacterial - chemically induced | Prospective Studies | Psoriasis - drug therapy | Risk Assessment | Humans | Infection - chemically induced | Infection - epidemiology | Skin Diseases, Bacterial - epidemiology | Registries | Granuloma - chemically induced | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Medical colleges | Care and treatment | Bacterial infections | Psoriasis | Family medicine | Dermatologic agents | Epidemiology | Risk factors | Necrosis | Tumor necrosis factor | Formulae, receipts, prescriptions | Health aspects | Tumors | Retinoids | Immunosuppressive agents | Methotrexate
Dermatology | immunosuppressive agents | anti-inflammatory agents | anti–tumor necrosis factor | psoriasis/drug therapy | safety | biological agents | RHEUMATOID-ARTHRITIS | LATENT TUBERCULOSIS INFECTION | BIOLOGICS | DERMATOLOGY | SYSTEMIC TREATMENT | DISEASE | anti-tumor necrosis factor | ADVERSE EVENTS | Granuloma - microbiology | Severity of Illness Index | Skin Diseases, Bacterial - chemically induced | Prospective Studies | Psoriasis - drug therapy | Risk Assessment | Humans | Infection - chemically induced | Infection - epidemiology | Skin Diseases, Bacterial - epidemiology | Registries | Granuloma - chemically induced | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Medical colleges | Care and treatment | Bacterial infections | Psoriasis | Family medicine | Dermatologic agents | Epidemiology | Risk factors | Necrosis | Tumor necrosis factor | Formulae, receipts, prescriptions | Health aspects | Tumors | Retinoids | Immunosuppressive agents | Methotrexate
Journal Article
3.
Infection
Japanese Journal of Chest Diseases, ISSN 0385-3667, 2015, Volume 74, pp. S28 - S31
Journal Article
Journal of Virology, ISSN 0022-538X, 12/2011, Volume 85, Issue 24, pp. 12844 - 12854
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley...
SIMPLEX-VIRUS TYPE-1 | HEPATITIS-B-VIRUS | VIROLOGY | MULTIVESICULAR BODIES | EXTRACELLULAR VESICLES | STRUCTURES L-PARTICLES | APOPTOTIC BODIES | CELL-DERIVED EXOSOMES | NASOPHARYNGEAL CARCINOMA-CELLS | LATENT MEMBRANE PROTEIN-1 | HUMAN T-CELLS | Exosomes - metabolism | Viruses - pathogenicity | Models, Biological | Humans | Viruses - growth & development | Exosomes - ultrastructure | Viruses - ultrastructure | Minireview
SIMPLEX-VIRUS TYPE-1 | HEPATITIS-B-VIRUS | VIROLOGY | MULTIVESICULAR BODIES | EXTRACELLULAR VESICLES | STRUCTURES L-PARTICLES | APOPTOTIC BODIES | CELL-DERIVED EXOSOMES | NASOPHARYNGEAL CARCINOMA-CELLS | LATENT MEMBRANE PROTEIN-1 | HUMAN T-CELLS | Exosomes - metabolism | Viruses - pathogenicity | Models, Biological | Humans | Viruses - growth & development | Exosomes - ultrastructure | Viruses - ultrastructure | Minireview
Journal Article
Annals of Internal Medicine, ISSN 0003-4819, 09/2014, Volume 161, Issue 6, pp. 419 - 428
Background: Effective treatment of latent tuberculosis infection (LTBI) is an important component of TB elimination programs. Promising new regimens that may...
PROPHYLAXIS | MEDICINE, GENERAL & INTERNAL | HIV-INFECTION | CHEMOPROPHYLAXIS REGIMENS | DOUBLE-BLIND | ADULTS | RIFAMPIN | PYRAZINAMIDE | RANDOMIZED CONTROLLED-TRIAL | ISONIAZID PREVENTIVE THERAPY | CHILDREN | Rifampin - analogs & derivatives | Antitubercular Agents - adverse effects | Pyrazinamide - adverse effects | Drug Administration Schedule | Humans | Isoniazid - adverse effects | Pyrazinamide - therapeutic use | Rifampin - adverse effects | Latent Tuberculosis - drug therapy | Isoniazid - therapeutic use | Rifampin - therapeutic use | Drug Therapy, Combination | Chemical and Drug Induced Liver Injury - etiology | Antitubercular Agents - therapeutic use | Care and treatment | Tuberculosis | Index Medicus | Abridged Index Medicus
PROPHYLAXIS | MEDICINE, GENERAL & INTERNAL | HIV-INFECTION | CHEMOPROPHYLAXIS REGIMENS | DOUBLE-BLIND | ADULTS | RIFAMPIN | PYRAZINAMIDE | RANDOMIZED CONTROLLED-TRIAL | ISONIAZID PREVENTIVE THERAPY | CHILDREN | Rifampin - analogs & derivatives | Antitubercular Agents - adverse effects | Pyrazinamide - adverse effects | Drug Administration Schedule | Humans | Isoniazid - adverse effects | Pyrazinamide - therapeutic use | Rifampin - adverse effects | Latent Tuberculosis - drug therapy | Isoniazid - therapeutic use | Rifampin - therapeutic use | Drug Therapy, Combination | Chemical and Drug Induced Liver Injury - etiology | Antitubercular Agents - therapeutic use | Care and treatment | Tuberculosis | Index Medicus | Abridged Index Medicus
Journal Article
PLoS Medicine, ISSN 1549-1277, 10/2016, Volume 13, Issue 10, p. e1002152
Background The existing estimate of the global burden of latent TB infection (LTBI) as "one-third" of the world population is nearly 20 y old. Given the...
MYCOBACTERIUM-TUBERCULOSIS | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | COUNTRIES | ACTIVE TUBERCULOSIS | REACTIVATION | REINFECTION | RISK | PREVALENCE | RELEASE ASSAYS | TRENDS | Isoniazid - pharmacology | Prevalence | Global Health | Humans | Antitubercular Agents - pharmacology | Latent Tuberculosis - epidemiology | Risk | Mycobacterium tuberculosis - drug effects | Tuberculosis, Multidrug-Resistant - epidemiology | Incidence | Tuberculosis, Multidrug-Resistant - microbiology | Mycobacterium tuberculosis - physiology | Latent Tuberculosis - microbiology | Epidemics | Usage | Tuberculosis | Distribution | United Kingdom | Mathematical models | Models | Research | Risk factors | Studies | Infectious diseases | Demography | Research & development--R&D | Population | Infections | Medical diagnosis | Estimates | Hygiene | Research & development | R&D
MYCOBACTERIUM-TUBERCULOSIS | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | COUNTRIES | ACTIVE TUBERCULOSIS | REACTIVATION | REINFECTION | RISK | PREVALENCE | RELEASE ASSAYS | TRENDS | Isoniazid - pharmacology | Prevalence | Global Health | Humans | Antitubercular Agents - pharmacology | Latent Tuberculosis - epidemiology | Risk | Mycobacterium tuberculosis - drug effects | Tuberculosis, Multidrug-Resistant - epidemiology | Incidence | Tuberculosis, Multidrug-Resistant - microbiology | Mycobacterium tuberculosis - physiology | Latent Tuberculosis - microbiology | Epidemics | Usage | Tuberculosis | Distribution | United Kingdom | Mathematical models | Models | Research | Risk factors | Studies | Infectious diseases | Demography | Research & development--R&D | Population | Infections | Medical diagnosis | Estimates | Hygiene | Research & development | R&D
Journal Article
Annals of Internal Medicine, ISSN 0003-4819, 08/2017, Volume 167, Issue 4, pp. 248 - 255
Background: Treatment of latent tuberculosis infection (LTBI) is an important component of tuberculosis (TB) control, and this study updates a previous network...
MEDICINE, GENERAL & INTERNAL | EFFICACY | DOUBLE-BLIND | ADULTS | ANTIRETROVIRAL THERAPY | RANDOMIZED CONTROLLED-TRIAL | PLACEBO-CONTROLLED TRIAL | RIFAPENTINE | ISONIAZID PREVENTIVE THERAPY | REGIMENS | CHILDREN | Antitubercular Agents - adverse effects | Pyrazinamide - adverse effects | Humans | Isoniazid - adverse effects | Pyrazinamide - therapeutic use | Rifampin - adverse effects | Latent Tuberculosis - drug therapy | Adult | Isoniazid - therapeutic use | Rifampin - therapeutic use | Network Meta-Analysis | Child | Chemical and Drug Induced Liver Injury - etiology | Drug Combinations | Antitubercular Agents - therapeutic use | Care and treatment | Usage | Dosage and administration | Tuberculosis | Rifampin | Meta-analysis | Index Medicus | Abridged Index Medicus
MEDICINE, GENERAL & INTERNAL | EFFICACY | DOUBLE-BLIND | ADULTS | ANTIRETROVIRAL THERAPY | RANDOMIZED CONTROLLED-TRIAL | PLACEBO-CONTROLLED TRIAL | RIFAPENTINE | ISONIAZID PREVENTIVE THERAPY | REGIMENS | CHILDREN | Antitubercular Agents - adverse effects | Pyrazinamide - adverse effects | Humans | Isoniazid - adverse effects | Pyrazinamide - therapeutic use | Rifampin - adverse effects | Latent Tuberculosis - drug therapy | Adult | Isoniazid - therapeutic use | Rifampin - therapeutic use | Network Meta-Analysis | Child | Chemical and Drug Induced Liver Injury - etiology | Drug Combinations | Antitubercular Agents - therapeutic use | Care and treatment | Usage | Dosage and administration | Tuberculosis | Rifampin | Meta-analysis | Index Medicus | Abridged Index Medicus
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 03/2007, Volume 175, Issue 5, pp. 514 - 520
Rationale: Two forms of the IFN-gamma release assay (IFNGRA) to detect tuberculosis infection are available, but neither has been evaluated in comparable...
Antigens | Diagnostic techniques and procedures | Interferons | CFP-10 protein | ESAT-6 protein | MYCOBACTERIUM-TUBERCULOSIS | DIAGNOSIS | GOLD | LATENT TUBERCULOSIS | INTERFERON-GAMMA ASSAY | ENUMERATION | antigens | diagnostic techniques and procedures | WHOLE-BLOOD | interferons | RESPIRATORY SYSTEM | ANERGY | RAPID DETECTION | CRITICAL CARE MEDICINE | Diagnosis, Differential | Reproducibility of Results | Cross-Sectional Studies | Follow-Up Studies | HIV Infections - virology | Humans | Male | CD4 Lymphocyte Count | Urban Population | Tuberculin Test | Tuberculosis, Pulmonary - complications | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | HIV-1 - immunology | Tuberculosis, Pulmonary - immunology | HIV Antigens - immunology | Tuberculosis, Pulmonary - diagnosis | HIV Infections - complications | Adult | Female
Antigens | Diagnostic techniques and procedures | Interferons | CFP-10 protein | ESAT-6 protein | MYCOBACTERIUM-TUBERCULOSIS | DIAGNOSIS | GOLD | LATENT TUBERCULOSIS | INTERFERON-GAMMA ASSAY | ENUMERATION | antigens | diagnostic techniques and procedures | WHOLE-BLOOD | interferons | RESPIRATORY SYSTEM | ANERGY | RAPID DETECTION | CRITICAL CARE MEDICINE | Diagnosis, Differential | Reproducibility of Results | Cross-Sectional Studies | Follow-Up Studies | HIV Infections - virology | Humans | Male | CD4 Lymphocyte Count | Urban Population | Tuberculin Test | Tuberculosis, Pulmonary - complications | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | HIV-1 - immunology | Tuberculosis, Pulmonary - immunology | HIV Antigens - immunology | Tuberculosis, Pulmonary - diagnosis | HIV Infections - complications | Adult | Female
Journal Article
Immunity, ISSN 1074-7613, 10/2017, Volume 47, Issue 4, pp. 766 - 775.e3
The latent reservoir for HIV-1 in resting memory CD4 T cells is the major barrier to curing HIV-1 infection. Studies of HIV-1 latency have focused on...
ACTIVATION | REPLICATION | PERSISTENCE | ACTIVE ANTIRETROVIRAL THERAPY | IN-VIVO | IMMUNODEFICIENCY-VIRUS TYPE-1 | IMMUNOLOGY | NF-KAPPA-B | EXPRESSION | VIRAL RESERVOIR | LYMPHOCYTES | Humans | Male | Host-Pathogen Interactions - immunology | CD4-Positive T-Lymphocytes - immunology | Lymphocyte Activation - genetics | Lymphocyte Activation - immunology | Flow Cytometry | HIV-1 - physiology | Female | Transcription, Genetic | CD4-Positive T-Lymphocytes - virology | Cellular Reprogramming - genetics | Cytokines - genetics | Immunologic Memory - genetics | Immunologic Memory - immunology | Cytokines - immunology | T-Lymphocytes, Cytotoxic - immunology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Gene Expression Profiling - methods | Virus Replication - immunology | Reverse Transcriptase Polymerase Chain Reaction | Cellular Reprogramming - immunology | HIV-1 - immunology | T-Lymphocytes, Cytotoxic - metabolism | Virus Latency - immunology | Immunological memory | CCR5 protein | Memory cells | Transcription | CD8 antigen | Memory | Latent infection | Effector cells | Viruses | Infections | Lymphocytes T | Vaccines | Kinases | Gene expression | CD4 antigen | Latency | Lymphocytes | Human immunodeficiency virus--HIV | Life cycle engineering | Chemokines | Life cycles
ACTIVATION | REPLICATION | PERSISTENCE | ACTIVE ANTIRETROVIRAL THERAPY | IN-VIVO | IMMUNODEFICIENCY-VIRUS TYPE-1 | IMMUNOLOGY | NF-KAPPA-B | EXPRESSION | VIRAL RESERVOIR | LYMPHOCYTES | Humans | Male | Host-Pathogen Interactions - immunology | CD4-Positive T-Lymphocytes - immunology | Lymphocyte Activation - genetics | Lymphocyte Activation - immunology | Flow Cytometry | HIV-1 - physiology | Female | Transcription, Genetic | CD4-Positive T-Lymphocytes - virology | Cellular Reprogramming - genetics | Cytokines - genetics | Immunologic Memory - genetics | Immunologic Memory - immunology | Cytokines - immunology | T-Lymphocytes, Cytotoxic - immunology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Gene Expression Profiling - methods | Virus Replication - immunology | Reverse Transcriptase Polymerase Chain Reaction | Cellular Reprogramming - immunology | HIV-1 - immunology | T-Lymphocytes, Cytotoxic - metabolism | Virus Latency - immunology | Immunological memory | CCR5 protein | Memory cells | Transcription | CD8 antigen | Memory | Latent infection | Effector cells | Viruses | Infections | Lymphocytes T | Vaccines | Kinases | Gene expression | CD4 antigen | Latency | Lymphocytes | Human immunodeficiency virus--HIV | Life cycle engineering | Chemokines | Life cycles
Journal Article
European Journal of Immunology, ISSN 0014-2980, 06/2013, Volume 43, Issue 6, pp. 1568 - 1577
Protective immunity to Mycobacterium tuberculosis (Mtb) remains poorly understood and the role of Mtb‐specific CD8+ T cells is controversial. Here we performed...
Functional profile | Cytotoxicity | Latent Mtb infection | Mtb‐specific CD8+ T cells | Active TB disease | T cells | Mtb-specific CD8 | MICE DEFICIENT | IMMUNOLOGY | GRANULYSIN | INTERFERON-GAMMA | PATHWAY | IMMUNE-RESPONSES | REACTIVATION | Mtb-specific CD8(+) T cells | PULMONARY TUBERCULOSIS | RESISTANCE | ANTIMICROBIAL ACTIVITY | ANTIGEN | T-Lymphocyte Subsets - immunology | Acute Disease | Cell Proliferation | Cytokines - metabolism | Humans | Cells, Cultured | Mycobacterium tuberculosis - immunology | Programmed Cell Death 1 Receptor - metabolism | Immunophenotyping | Latent Tuberculosis - immunology | Signaling Lymphocytic Activation Molecule Family | GPI-Linked Proteins - metabolism | Antigens, CD - metabolism | Tuberculosis, Pulmonary - immunology | CD8-Positive T-Lymphocytes - immunology | Receptors, Immunologic - metabolism | Health aspects | Tuberculosis | T cell receptors | Immunology | Lymphocytes | Mtb-specific CD8+ T cells
Functional profile | Cytotoxicity | Latent Mtb infection | Mtb‐specific CD8+ T cells | Active TB disease | T cells | Mtb-specific CD8 | MICE DEFICIENT | IMMUNOLOGY | GRANULYSIN | INTERFERON-GAMMA | PATHWAY | IMMUNE-RESPONSES | REACTIVATION | Mtb-specific CD8(+) T cells | PULMONARY TUBERCULOSIS | RESISTANCE | ANTIMICROBIAL ACTIVITY | ANTIGEN | T-Lymphocyte Subsets - immunology | Acute Disease | Cell Proliferation | Cytokines - metabolism | Humans | Cells, Cultured | Mycobacterium tuberculosis - immunology | Programmed Cell Death 1 Receptor - metabolism | Immunophenotyping | Latent Tuberculosis - immunology | Signaling Lymphocytic Activation Molecule Family | GPI-Linked Proteins - metabolism | Antigens, CD - metabolism | Tuberculosis, Pulmonary - immunology | CD8-Positive T-Lymphocytes - immunology | Receptors, Immunologic - metabolism | Health aspects | Tuberculosis | T cell receptors | Immunology | Lymphocytes | Mtb-specific CD8+ T cells
Journal Article
Clinical Microbiology and Infection, ISSN 1198-743X, 06/2011, Volume 17, Issue 6, pp. 806 - 814
Identification of latent tuberculosis (TB) infection and preventive therapy is important for TB control, especially in high-risk populations. Since the advent...
guidelines | interferon-γ release assays | Diagnosis | immunodiagnostics | tuberculosis | interferon‐γ release assays | Immunodiagnostics | Tuberculosis | Interferon-γ release assays | Guidelines | MYCOBACTERIUM-TUBERCULOSIS | UNITED-STATES | TESTS | INFECTIOUS DISEASES | MANAGEMENT | QUALITY | LATENT TUBERCULOSIS | PREVENTION | MICROBIOLOGY | RECOMMENDATIONS | interferon-gamma release assays | Immunoassay - methods | Interferons - secretion | Clinical Laboratory Techniques - methods | Guidelines as Topic | Tuberculosis - diagnosis | Humans | Infection | Risk groups | Discordance | gamma -Interferon | Tuberculin | Skin tests
guidelines | interferon-γ release assays | Diagnosis | immunodiagnostics | tuberculosis | interferon‐γ release assays | Immunodiagnostics | Tuberculosis | Interferon-γ release assays | Guidelines | MYCOBACTERIUM-TUBERCULOSIS | UNITED-STATES | TESTS | INFECTIOUS DISEASES | MANAGEMENT | QUALITY | LATENT TUBERCULOSIS | PREVENTION | MICROBIOLOGY | RECOMMENDATIONS | interferon-gamma release assays | Immunoassay - methods | Interferons - secretion | Clinical Laboratory Techniques - methods | Guidelines as Topic | Tuberculosis - diagnosis | Humans | Infection | Risk groups | Discordance | gamma -Interferon | Tuberculin | Skin tests
Journal Article
JAMA, ISSN 0098-7484, 09/2016, Volume 316, Issue 9, pp. 962 - 969
IMPORTANCE: Tuberculosis remains an important preventable disease in the United States. An effective strategy for reducing the transmission, morbidity, and...
RIFAMPIN | MEDICINE, GENERAL & INTERNAL | Mass Screening | Tuberculosis | Risk Assessment | Humans | Adult | Primary Health Care | Advisory Committees | Latent Tuberculosis | Adults | Medical screening | Medical treatment
RIFAMPIN | MEDICINE, GENERAL & INTERNAL | Mass Screening | Tuberculosis | Risk Assessment | Humans | Adult | Primary Health Care | Advisory Committees | Latent Tuberculosis | Adults | Medical screening | Medical treatment
Journal Article