X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
lats2 (114) 114
index medicus (76) 76
humans (71) 71
cancer (48) 48
oncology (48) 48
protein-serine-threonine kinases - metabolism (48) 48
apoptosis (47) 47
protein-serine-threonine kinases - genetics (47) 47
cell biology (41) 41
expression (41) 41
tumor suppressor proteins - genetics (41) 41
tumor suppressor proteins - metabolism (41) 41
down-regulation (39) 39
gene expression (37) 37
proliferation (37) 37
hippo pathway (33) 33
animals (30) 30
biochemistry & molecular biology (30) 30
female (30) 30
signal transduction (30) 30
yap (29) 29
metastasis (26) 26
cell line, tumor (25) 25
genetic aspects (25) 25
kinases (25) 25
tumors (25) 25
cell proliferation (24) 24
phosphorylation (23) 23
proteins (23) 23
tumor suppressor genes (23) 23
male (21) 21
mice (20) 20
microrna (20) 20
analysis (18) 18
prognosis (18) 18
gene (17) 17
gene expression regulation, neoplastic (17) 17
growth (17) 17
micrornas (17) 17
putative tumor-suppressor (17) 17
research (17) 17
breast cancer (16) 16
development and progression (16) 16
health aspects (16) 16
inhibition (16) 16
lats1 (16) 16
tumor-suppressor (16) 16
tumorigenesis (16) 16
cell cycle (15) 15
invasion (15) 15
adaptor proteins, signal transducing - metabolism (14) 14
human homolog (14) 14
phosphoproteins - metabolism (14) 14
protein-kinase (14) 14
cell growth (13) 13
medicine, research & experimental (13) 13
middle aged (13) 13
polymerase chain reaction (13) 13
promoter hypermethylation (13) 13
cell-proliferation (12) 12
cells, cultured (12) 12
micrornas - genetics (12) 12
rna (12) 12
yes-associated protein (12) 12
genetics & heredity (11) 11
medical prognosis (11) 11
aged (10) 10
cells (10) 10
colorectal cancer (10) 10
epithelial-mesenchymal transition (10) 10
genes (10) 10
hepatocellular carcinoma (10) 10
hippo (10) 10
liver cancer (10) 10
p53 (10) 10
pathology (10) 10
adult (9) 9
carcinoma (9) 9
genes, tumor suppressor (9) 9
methylation (9) 9
mir-372 (9) 9
original article (9) 9
protein-serine-threonine kinases - physiology (9) 9
rna interference (9) 9
stem cells (9) 9
transcription factors - metabolism (9) 9
care and treatment (8) 8
cell line (8) 8
drosophila (8) 8
homolog (8) 8
lung neoplasms - genetics (8) 8
micrornas - metabolism (8) 8
neoplasms. tumors. oncology. including cancer and carcinogens (8) 8
original (8) 8
protein (8) 8
taz (8) 8
tumor suppressor proteins - physiology (8) 8
adaptor proteins, signal transducing - genetics (7) 7
article (7) 7
cell migration (7) 7
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Oncotarget, ISSN 1949-2553, 07/2018, Volume 9, Issue 53, pp. 30053 - 30065
Ovarian cancer is the most aggressive female reproductive tract tumours. Taxane (paclitaxel; TX) is widely used for ovarian cancer treatment. However, ovarian... 
LATS2 | Taxane | MiR-363 | Chemoresistance | Ovarian cancer
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 08/2019, Volume 856, p. 172352
Nasopharyngeal Carcinoma is limited by the various severe side-effects and surgery is rarely performed. Iosliquiritigenin has a series of biological... 
Nasopharyngeal carcinoma | Cell proliferation | Isoliquiritigenin | LATS2 | Wnt | microRNA-32 | MIGRATION | ACTIVATION | CELL-PROLIFERATION | CANCER | INVASION | MIR-32 | PHARMACOLOGY & PHARMACY | EXPRESSION | TUMORIGENESIS
Journal Article
Journal of Lower Genital Tract Disease, ISSN 1089-2591, 07/2019, Volume 23, Issue 3, pp. 214 - 219
Journal Article
Experimental Cell Research, ISSN 0014-4827, 08/2004, Volume 298, Issue 2, pp. 329 - 338
Lats2, also known as Kpm, is the second mammalian member of the novel Lats tumor suppressor gene family. Recent studies have demonstrated that Lats2 negatively... 
Bcl-2 | Caspase | Putative tumor suppressor | Bcl-x | Human Lats2 | Apoptosis
Journal Article
ONCOGENE, ISSN 0950-9232, 01/2015, Volume 34, Issue 1, pp. 73 - 83
Malignant mesothelioma (MM) is one of the most aggressive neoplasms usually associated with asbestos exposure and is highly refractory to current therapeutic... 
APOPTOSIS | GROWTH-CONTROL | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | YAP | MITOTIC PROGRESSION | FOXM1 | CANCER | DROSOPHILA | CELL BIOLOGY | ORGANIZATION | Hippo pathway | LATS2 | ONCOLOGY | malignant nnesothelioma | GENETICS & HEREDITY | SCAFFOLD PROTEINS | AJUBA | YAP PATHWAY
Journal Article
Journal of Experimental and Clinical Cancer Research, ISSN 1756-9966, 11/2017, Volume 36, Issue 1, pp. 161 - 20
Background: Dysregulation of miRNAs is associated with cancer development by coordinately suppressing abundant target genes. Emerging evidence indicates that... 
miR-31 | Esophageal squamous cell carcinoma | Hippo pathway | LATS2 | TAZ | EMT | CANCER-CELLS | METASTASIS | LARGE TUMOR-SUPPRESSOR | TARGETING LATS2 | SELF-RENEWAL | PROLIFERATION | MICRORNA-31 | INVASION | HOMOLOG 2 | ONCOLOGY | GROWTH | Neoplasm Transplantation | Cell Proliferation | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Gene Expression Regulation, Neoplastic | Male | Esophageal Neoplasms - pathology | Esophageal Neoplasms - metabolism | Tumor Suppressor Proteins - genetics | Epithelial-Mesenchymal Transition | Female | 3' Untranslated Regions | Protein-Serine-Threonine Kinases - metabolism | Esophageal Squamous Cell Carcinoma | Tumor Suppressor Proteins - metabolism | Signal Transduction | Neoplasm Invasiveness | Down-Regulation | Protein-Serine-Threonine Kinases - genetics | Animals | Esophageal Neoplasms - genetics | Cell Line, Tumor | Mice | MicroRNAs - genetics | Neoplasm Staging | Squamous cell carcinoma | MicroRNA | Physiological aspects | Development and progression | Genetic aspects | Research | Esophageal cancer | Medical research | Transcription factors | Homeostasis | Breast cancer | Metastasis | Gene expression | Kinases | Ovarian cancer | Proteins | Cell growth | Medical prognosis | MicroRNAs | Stem cells | Cell cycle | Tumors | Apoptosis
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2019, Volume 1893, pp. 305 - 317
The Hippo tissue growth control and regeneration pathway is a main regulator of the YAP/TAZ effectors. In this regard, the LATS/NDR serine/threonine protein... 
LATS1 | NDR1 | NDR2 | Hippo pathway | Kinase assays | Kinase substrates | LATS2 | STK38 | STK38L | Protein kinases
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 07/2019, Volume 514, Issue 4, pp. 1051 - 1057
Long noncoding RNAs (lncRNAs), a group of transcripts without protein coding potential, have been reported to play critical roles in progression of... 
Hepatocellular carcinoma | LATS2 | Epigenetic | DDX11-AS1 | METHYLATION | METASTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-PROLIFERATION | CANCER | BIOPHYSICS | GENE | PROMOTES | PROGRESSION | Epigenetic inheritance | Methyltransferases | Liver | Transplantation of organs, tissues, etc | Development and progression | Antisense RNA | Hepatoma | Health aspects
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2013, Volume 288, Issue 6, pp. 3977 - 3988
Journal Article
Cancer Science, ISSN 1347-9032, 07/2019, Volume 110, Issue 7, pp. 2284 - 2295
Cell adhesion molecule‐1 (CADM1) is a member of the immunoglobulin superfamily that functions as a tumor suppressor of lung tumors. We herein demonstrated that... 
YAP1 | Hippo pathway | LATS2 | CADM1 | lung adenocarcinoma | YES-ASSOCIATED PROTEIN | SUPPRESSOR | ORGAN SIZE CONTROL | ADENOCARCINOMA | ADHESION | ONCOLOGY | CLONING | GENE-TRANSFER | DIFFERENTIATION | TSLC1 | EXPRESSION | Prognosis | Gene expression | Lung cancer | Analysis | Tumors | Original
Journal Article
Nature, ISSN 0028-0836, 01/2017, Volume 541, Issue 7638, pp. 541 - 545
Journal Article
Science Signaling, ISSN 1945-0877, 02/2015, Volume 8, Issue 363
Journal Article
Journal of Isfahan Medical School, ISSN 1027-7595, 2015, Volume 32, Issue 311
Journal Article
Journal Article
Journal of Cell Science, ISSN 0021-9533, 2013, Volume 126, Issue 19, pp. 4358 - 4368
LATS2 (Large tumor suppressor 2), a member of the conserved AGC Ser/Thr (S/T) kinase family, is a human tumor suppressor gene. Here, we show that in response... 
Lats2 | Phosphorylation | Cdkn1A | P21 | Apoptosis | UV | CDKN1A | PROTEIN | DNA-DAMAGE RESPONSE | KINASE | PUTATIVE TUMOR-SUPPRESSOR | FAS-MEDIATED APOPTOSIS | p21 | CELL BIOLOGY | P53-MEDIATED APOPTOSIS | CASPASE 3 | SIGNALING PATHWAY | DEGRADATION
Journal Article