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lats2 (120) 120
science & technology (114) 114
life sciences & biomedicine (112) 112
humans (63) 63
protein-serine-threonine kinases - genetics (47) 47
protein-serine-threonine kinases - metabolism (47) 47
oncology (45) 45
tumor suppressor proteins - metabolism (44) 44
cell biology (43) 43
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gene expression (36) 36
apoptosis (34) 34
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animals (28) 28
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cell proliferation (27) 27
biochemistry & molecular biology (26) 26
cell line, tumor (26) 26
proteins (26) 26
tumor suppressor genes (25) 25
cancer (23) 23
kinases (23) 23
metastasis (22) 22
yap (22) 22
genetic aspects (21) 21
hippo pathway (20) 20
phosphorylation (20) 20
mice (19) 19
cell cycle (18) 18
analysis (17) 17
lats1 (17) 17
male (17) 17
breast cancer (16) 16
cell growth (16) 16
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adaptor proteins, signal transducing - metabolism (15) 15
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gene expression regulation, neoplastic (15) 15
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research & experimental medicine (15) 15
medical prognosis (14) 14
phosphoproteins - metabolism (14) 14
microrna (13) 13
middle aged (13) 13
polymerase chain reaction (12) 12
aged (11) 11
hepatocellular carcinoma (11) 11
micrornas (11) 11
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cell migration (10) 10
cells, cultured (10) 10
genes (10) 10
genetics & heredity (10) 10
immunohistochemistry (10) 10
micrornas - genetics (10) 10
original article (10) 10
stem cells (10) 10
yes-associated protein (10) 10
colorectal cancer (9) 9
down-regulation (9) 9
hippo (9) 9
liver cancer (9) 9
medical research (9) 9
neoplasms. tumors. oncology. including cancer and carcinogens (9) 9
original (9) 9
proliferation (9) 9
protein-serine-threonine kinases - physiology (9) 9
rna (9) 9
taz (9) 9
transcription factors - metabolism (9) 9
tumorigenesis (9) 9
biological and medical sciences (8) 8
digestive system diseases (8) 8
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tumor suppressor proteins - physiology (8) 8
cancer therapies (7) 7
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lung neoplasms - genetics (7) 7
micrornas - metabolism (7) 7
mir-372 (7) 7
mutation (7) 7
p53 (7) 7
research paper (7) 7
rna interference (7) 7
adaptor proteins, signal transducing - genetics (6) 6
biotechnology (6) 6
care and treatment (6) 6
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1. Full Text Citron kinase interacts with LATS2 and inhibits its activity by occluding its hydrophobic phosphorylation motif
by Thi Hai Yen Tran and Yang, Dae-Wook and Kim, Minchul and Lee, Da-Hye and Gai, Marta and Di Cunto, Ferdinando and Choi, Kwang-Wook and Lim, Dae-Sik
Journal of molecular cell biology, ISSN 1674-2788, 11/2019, Volume 11, Issue 11, pp. 1006 - 1017
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus
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2. Full Text The tumor suppressor LATS2 reduces v‐Src‐induced membrane blebs in a kinase activity‐independent manner
by Ikeuchi, Masayoshi and Yuki, Ryuzaburo and Saito, Youhei and Nakayama, Yuji
The FASEB journal, ISSN 0892-6638, 01/2021, Volume 35, Issue 1, pp. e21242 - n/a
bleb | v‐Src | Hippo pathway | LATS2 | Merlin | Index Medicus
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3. Full Text RETRACTED ARTICLE: LATS2 overexpression attenuates the therapeutic resistance of liver cancer HepG2 cells to sorafenib-mediated death via inhibiting the AMPK–Mfn2 signaling pathway
by Song, Jie and Zhao, Wei and Lu, Chang and Shao, Xue
Cancer cell international, ISSN 1475-2867, 03/2019, Volume 19, Issue 1, pp. 1 - 15
HCC | LATS2 | Mitophagy | AMPK pathway | Sorafenib
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4. Full Text miR-363 confers taxane resistance in ovarian cancer by targeting the Hippo pathway member, LATS2
by Mohamed, Zeinab and Hassan, Mohamed Kamel and Okasha, Safwat and Mitamura, Takashi and Keshk, Sarah and Konno, Yusuke and Kato, Tatsuya and EL-Khamisy, Sherif F and Ohba, Yusuke and Watari, Hidemichi
Oncotarget, ISSN 1949-2553, 07/2018, Volume 9, Issue 53, pp. 30053 - 30065
LATS2 | Taxane | MiR-363 | Chemoresistance | Ovarian cancer
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5. Full Text LINC00689 participates in proliferation, chemoresistance and metastasis via miR-31-5p/YAP/β-catenin axis in colorectal cancer
by Du, Yong-Liang and Liang, Yan and Shi, Guang-Qing and Cao, Yan and Qiu, Juan and Yuan, Li and Yong, Zhong and Liu, Le and Li, Jian
Experimental cell research, ISSN 0014-4827, 10/2020, Volume 395, Issue 1, pp. 112176 - 112176
LINC00689 | LATS2 | CRC | YAP/β-catenin | miR-31-5p | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus
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6. Full Text Circular RNA circ_0001368 inhibited growth and invasion in renal cell carcinoma by sponging miR-492 and targeting LATS2
by Chen, Lin and Wu, Denglong and Ding, Tao
Gene, ISSN 0378-1119, 08/2020, Volume 753, pp. 144781 - 144781
Circ_0001368 | Noncoding RNA | MiR-492 | LATS2 | Renal cell carcinoma | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Index Medicus
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7. Full Text Long noncoding RNA DDX11-AS1 epigenetically represses LATS2 by interacting with EZH2 and DNMT1 in hepatocellular carcinoma
by Li, Yong and Zhuang, Wenlong and Huang, Maosheng and Li, Xiangcheng
Biochemical and biophysical research communications, ISSN 0006-291X, 07/2019, Volume 514, Issue 4, pp. 1051 - 1057
Hepatocellular carcinoma | LATS2 | Epigenetic | DDX11-AS1 | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Epigenetic inheritance | Methyltransferases | Liver | Transplantation of organs, tissues, etc | Development and progression | Antisense RNA | Hepatoma | Health aspects | Index Medicus
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8. Full Text Anti-tumor effect of LATS2 on liver cancer death: Role of DRP1-mediated mitochondrial division and the Wnt/β-catenin pathway
by Zhang, Lijuan and Li, Shuping and Wang, Rong and Chen, Changyuan and Ma, Wen and Cai, Hongyi
Biomedicine & pharmacotherapy, ISSN 0753-3322, 06/2019, Volume 114, pp. 108825 - 108825
Mitochondria | LATS2 | Wnt/β-catenin pathway | DRP1 | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Index Medicus
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9. Full Text Clinicopathological significance of large tumor suppressor (LATS) expression in gastric cancer
by Son, Myoung Won and Song, Geum Jong and Jang, Si-Hyong and Hong, Soon Auck and Oh, Mee-Hye and Lee, Ji-Hye and Baek, Moo Jun and Lee, Moon Soo
Journal of gastric cancer, ISSN 2093-582X, 12/2017, Volume 17, Issue 4, pp. 363 - 373
Human | Tumor suppressor genes | LATS2 protein | LATS1 protein | Stomach neoplasms | Gastroenterology & Hepatology | Oncology | Life Sciences & Biomedicine | Science & Technology | LATS1 protein, human | LATS2 protein, human | Original | 일반외과학
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10. Full Text Hippo pathway and tumoral FOXP3 expression correlate with tumor growth in squamous cell carcinoma of the lung
by Won, Kyu Yeoun and Kim, Hyung Kyung and Kim, Gou Young and Song, Min Jeong and Lim, Sung-Jig
Pathology, research and practice, ISSN 0344-0338, 07/2020, Volume 216, Issue 7, pp. 153003 - 153003
YAP | Squamous cell carcinoma | Lats2 | Hippo pathway | FOXP3 | Lung | Life Sciences & Biomedicine | Pathology | Science & Technology | Index Medicus
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11. Full Text miR-31及其靶基因LATS2在大鼠肥大心肌细胞中的表达
by 曾俊义 and 张婉 and 丁露 and 魏云峰 and 郑泽琪 and 文通 and 易达松
基础医学与临床, ISSN 1001-6325, 2016, Volume 36, Issue 11, pp. 1537 - 1541
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12. Full Text The novel long non-coding RNA LATS2-AS1-001 inhibits gastric cancer progression by regulating the LATS2/YAP1 signaling pathway via binding to EZH2
by Sun, Dan and Wang, Ying and Wang, Huan and Xin, Yan
Cancer cell international, ISSN 1475-2867, 05/2020, Volume 20, Issue 1, pp. 1 - 204
Life Sciences & Biomedicine | Oncology | Science & Technology | Phosphorylation | Immunoprecipitation | Transcription | Mucosa | Antibodies | Cell viability | Metastasis | Kinases | Experiments | Stomach cancer | Cell adhesion & migration | Proteins | Signal transduction | Cell growth | Cell cycle | Gastric cancer | G1 phase | Wound healing | Antisense RNA | RNA polymerase | Gene expression | Yes-associated protein | Plasmids | Correlation analysis | Non-coding RNA | Cell migration | Apoptosis | Tumors | Yes-associated protein 1/YAP1 | Large tumor suppressor 2/LATS2 | Enhancer of zeste homolog 2/EZH2 | Long non-coding RNA
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13. Full Text Putative tumor suppressor Lats2 induces apoptosis through downregulation of Bcl-2 and Bcl-xL
by Ke, Hengning and Pei, Jing and Ni, Zhenya and Xia, Hong and Qi, Huilin and Woods, Tishonna and Kelekar, Ameeta and Tao, Wufan
Experimental cell research, ISSN 0014-4827, 08/2004, Volume 298, Issue 2, pp. 329 - 338
Bcl-2 | Caspase | Putative tumor suppressor | Bcl-x | Human Lats2 | Apoptosis
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14. Full Text The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα
by Britschgi, Adrian and Duss, Stephan and Kim, Sungeun and Couto, Joana Pinto and Brinkhaus, Heike and Koren, Shany and De Silva, Duvini and Mertz, Kirsten D and Kaup, Daniela and Varga, Zsuzsanna and Voshol, Hans and Vissieres, Alexandra and Leroy, Cedric and Roloff, Tim and Stadler, Michael B and Scheel, Christina H and Miraglia, Loren J and Orth, Anthony P and Bonamy, Ghislain M. C and Reddy, Venkateshwar A and Bentires-Alj, Mohamed
Nature (London), ISSN 0028-0836, 01/2017, Volume 541, Issue 7638, pp. 541 - 545
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Protein-Serine-Threonine Kinases - deficiency | Tumor Suppressor Proteins - metabolism | Signal Transduction | Breast - cytology | Breast - enzymology | Humans | Cells, Cultured | Ubiquitin - metabolism | Phosphoproteins - agonists | Adaptor Proteins, Signal Transducing - agonists | Phosphoproteins - metabolism | Cell Lineage | Carrier Proteins - metabolism | Estrogen Receptor alpha - agonists | Proteolysis | Tumor Suppressor Proteins - deficiency | Estrogen Receptor alpha - metabolism | Female | Cell Differentiation | Proteasome Endopeptidase Complex - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Breast - pathology | Genes, Tumor Suppressor | Protein-Serine-Threonine Kinases - metabolism | Index Medicus | LATS1 | LATS2 | c-KIT | ERα | Hippo | cell fate | luminal progenitor | YAP | breast cancer | TAZ | breast
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