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by Kapelios, Chris J and Lainscak, Mitja and Savarese, Gianluigi and Laroche, Cécile and Seferovic, Petar and Ruschitzka, Frank and Coats, Andrew and Anker, Stefan D and Crespo-Leiro, Maria G and Filippatos, Gerasimos and Piepoli, Massimo F and Rosano, Giuseppe and Zanolla, Luisa and Aguiar, Carlos and Murin, Jan and Leszek, Przemyslaw and McDonagh, Theresa and Maggioni, Aldo P and Lund, Lars H and Auer, J and Ablasser, K and Fruhwald, F and Dolze, T and Brandner, K and Gstrein, S and Poelzl, G and Moertl, D and Reiter, S and Podczeck-Schweighofer, A and Muslibegovic, A and Vasilj, M and Fazlibegovic, E and Cesko, M and Zelenika, D and Palic, B and Pravdic, D and Cuk, D and Vitlianova, K and Katova, T and Velikov, T and Kurteva, T and Gatzov, P and Kamenova, D and Antova, M and Sirakova, V and Krejci, J and Mikolaskova, M and Spinar, J and Krupicka, J and Malek, F and Hegarova, M and Lazarova, M and Monhart, Z and Hassanein, M and Sobhy, M and El Messiry, F and El Shazly, A.H and Elrakshy, Y and Youssef, A and Moneim, A.A and Noamany, M and Reda, A and Abdel Dayem, T.K and Farag, N and Ibrahim Halawa, S and Abdel Hamid, M and Said, K and Saleh, A and Ebeid, H and Hanna, R and Aziz, R and Louis, O and Enen, M.A and Ibrahim, B.S and Nasr, G and Elbahry, A and Sobhy, H and Ashmawy, M and Gouda, M and Aboleineen, W and Bernard, Y and Luporsi, P and Meneveau, N and Pillot, M and Morel, M and Seronde, M.-F and Schiele, F and Briand, F and Delahaye, F and Damy, T and Eicher, J.-C and de Groote, P and Fertin, M and Lamblin, N and Isnard, R and Lefol, C and Thevenin, S and Hagege, A and Jondeau, G and Logeart, D and ... and HF-LT Registry Investigators Group and on behalf of the HF‐LT Registry Investigators Group
European Journal of Heart Failure, ISSN 1388-9842, 2019
To assess the proportion of patients with heart failure and reduced ejection fraction (HFrEF) who are eligible for sacubitril/valsartan (LCZ696) based on the... 
Sacubitril/valsartan | LCZ696 | Eligibility | Prognosis | Registry | Angiotensin receptor–neprilysin inhibitor
Journal Article
Vnitrni Lekarstvi, ISSN 0042-773X, 2015, Volume 61, Issue 2, pp. 129 - 133
Journal Article
Canadian Journal of Cardiology, ISSN 0828-282X, 03/2018, Volume 34, Issue 3, pp. 343.e5 - 343.e7
Vasoplegia occurs in up to 16% of patients who undergo heart transplantation (HT) and is associated with significant morbidity and mortality. We present a case... 
NEPRILYSIN | CARDIAC & CARDIOVASCULAR SYSTEMS | LCZ696 | FAILURE
Journal Article
Blood Pressure, ISSN 0803-7051, 03/2019, Volume 28, Issue 2, pp. 75 - 76
Journal Article
Journal of Chromatographic Science, ISSN 0021-9665, 07/2018, Volume 56, Issue 6, pp. 498 - 509
Abstract Valsartan (VAL) and sacubitril (SAC) are combined in a supramolecular complex, LCZ696, which is a newly approved remedy for heart failure. SAC-related... 
RP-HPLC | CHEMISTRY, ANALYTICAL | RECEPTOR | LCZ696 | BIOCHEMICAL RESEARCH METHODS | HYDROCHLOROTHIAZIDE
Journal Article
Scientific Reports, ISSN 2045-2322, 06/2016, Volume 6, Issue 1, p. 27909
Sacubitril is an ethyl ester prodrug of LBQ657, the active neprilysin (NEP) inhibitor, and a component of LCZ696 (sacubitril/valsartan). We report herein the... 
REFINEMENT | POTENT | PHOSPHORAMIDON | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | NEUTRAL ENDOPEPTIDASE INHIBITORS | LCZ696
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 07/2018, Volume 72, Issue 1, pp. 41 - 44
To date, heart failure (HF) with preserved ejection fraction (HFpEF) has been one of the most frustrating and sobering conditions in cardiovascular medicine.... 
heart failure | HFpEF | troponin | biomarker | TRIAL | CARDIAC & CARDIOVASCULAR SYSTEMS | NEPRILYSIN INHIBITOR LCZ696 | DRUG DEVELOPMENT | ELEVATION | DEATH | Heart failure | Troponin | Exercise | Ischemia | Calcium-binding protein | Medical prognosis | Clinical trials | Cardiovascular disease | Heart diseases | Clinical outcomes | Ejection
Journal Article
Organic Process Research and Development, ISSN 1083-6160, 01/2019, Volume 23, Issue 1, pp. 102 - 107
An efficient industrial synthetic process for sacubitril has been developed. Stereoisomers derived from sacubitril and its crucial intermediate have been... 
stereoisomers | AHU-377 | valsartan | LCZ696 | sacubitril | development of HPLC methods | ACID | CHEMISTRY, ORGANIC | CHEMISTRY, APPLIED
Journal Article
Nephrology Dialysis Transplantation, ISSN 0931-0509, 12/2017, Volume 32, Issue 12, pp. 2043 - 2051
Journal Article
European Heart Journal, ISSN 0195-668X, 03/2017, Volume 38, Issue 10, pp. 705 - 711
Journal Article
Intervencni a Akutni Kardiologie, ISSN 1213-807X, 2018, Volume 17, Issue 1, pp. 36 - 38
Journal Article
Journal of Hypertension, ISSN 0263-6352, 04/2017, Volume 35, Issue 4, pp. 726 - 728
Journal Article
European Journal of Heart Failure, ISSN 1388-9842, 2013, Volume 15, Issue 9, pp. 1062 - 1073
Journal Article