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Journal of the American College of Cardiology, ISSN 0735-1097, 2017, Volume 69, Issue 5, pp. 471 - 482
PCSK9 | clinical trials | LDL-C | safety | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Propensity Score | Follow-Up Studies | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Cholesterol, LDL - blood | Female | Male | Safety | Hypercholesterolemia - drug therapy | Randomized Controlled Trials as Topic | Laboratories | Vitamin E | Low density lipoprotein | Statins | Index Medicus | Abridged Index Medicus
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 2017, Volume 69, Issue 7, pp. 789 - 800
Cardiovascular | Internal Medicine | mass spectrometry | triglycerides | proteomics | lipidomics | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Apolipoprotein C-III - antagonists & inhibitors | Prospective Studies | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Male | Apolipoproteins - blood | Incidence | Lipoproteins, VLDL - blood | Mass Spectrometry | Cardiovascular Diseases - blood | Cardiovascular Diseases - epidemiology | Female | Aged | Medical colleges | Research institutes | Blood lipids | Apolipoproteins | Low density lipoproteins | Analysis | Mass spectrometry | Heart attack | Blood proteins | Studies | Lipids | Low density lipoprotein | Statins | Index Medicus | Abridged Index Medicus | HDL-C, high-density lipoprotein cholesterol | MS, mass spectrometry | PC, phosphatidylcholine | LDL-C, low-density lipoprotein cholesterol | CE, cholesterol ester | CVD, cardiovascular disease | DAG, diacylglycerol | VLDL, very-low-density lipoprotein | TAG, triacylglycerol | TG, triglyceride | TRL, triglyceride-rich lipoprotein | apo, apolipoprotein | FCS, familial chylomicronemia syndrome | MRM, multiple reaction monitoring | HDL, high-density lipoprotein | LDL, low-density lipoprotein | Original Investigation
Journal Article
Journal of clinical lipidology, ISSN 1933-2874, 2017, Volume 11, Issue 4, pp. 1065 - 1072
Cardiovascular | Lipids | PCSK9 | Non-HDL-C | LDL-C | ASCVD | ApoB | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Blood Chemical Analysis - methods | Cross-Sectional Studies | Nutrition Surveys | Humans | Middle Aged | Male | Apolipoproteins B - blood | Atherosclerosis - blood | Young Adult | Health Surveys | Adolescent | Adult | Cholesterol, LDL - blood | Female | Aged | Index Medicus
Journal Article
Lipids, ISSN 0024-4201, 01/2021, Volume 56, Issue 1, pp. 59 - 68
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 11/2012, Volume 60, Issue 19, pp. 1888 - 1898
LDL-C | PCSK9 | hypercholesterolemia | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Biological and medical sciences | Metabolic diseases | Medical sciences | Disorders of blood lipids. Hyperlipoproteinemia | Proprotein Convertases - antagonists & inhibitors | Hypercholesterolemia - blood | Double-Blind Method | Antibodies, Monoclonal - pharmacology | Humans | Proprotein Convertases - metabolism | Receptors, LDL - antagonists & inhibitors | Cholesterol, LDL - antagonists & inhibitors | Receptors, LDL - metabolism | Antibodies, Monoclonal - therapeutic use | Male | Treatment Outcome | Hypercholesterolemia - drug therapy | Dose-Response Relationship, Drug | Young Adult | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Adult | Cholesterol, LDL - blood | Female | Serine Endopeptidases - metabolism | Cohort Studies | Proprotein Convertase 9 | Index Medicus | Abridged Index Medicus
Journal Article
Atherosclerosis, ISSN 0021-9150, 2017, Volume 261, pp. 60 - 68
Cardiovascular | Low-density lipoprotein cholesterol-receptor | Annexin A2 | Single nucleotide polymorphism | Proprotein convertase subtilisin/kexin type-9 | Coronary heart disease | Low-density lipoprotein cholesterol | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Humans | Middle Aged | Databases, Genetic | Male | Transfection | Cholesterol, LDL - blood | Female | Genes, Reporter | Coronary Disease - blood | Genetic Predisposition to Disease | Genetic Association Studies | Gene Frequency | Computational Biology | United Kingdom | Biomarkers - blood | Coronary Disease - diagnosis | Proprotein Convertase 9 - metabolism | Hep G2 Cells | Linkage Disequilibrium | Homozygote | Phenotype | Annexin A2 - genetics | Coronary Disease - genetics | K562 Cells | Heterozygote | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Annexin A2 - metabolism | Medical colleges | Low density lipoproteins | Genetic research | Research institutes | Annexins | Epidemiology | Cholesterol | Analysis | Index Medicus | LDL-C, low-density lipoprotein cholesterol | LDLR, low-density lipoprotein cholesterol-receptor | AnxA2, annexin A2 | Proprotein convertase subtilisin | FAIRE, formaldehyde assisted isolation of regulatory elements | NPHSII, Second-Northwick-Park Heart Study | CHRD, cysteine-histidine-rich domain of PCSK9 | UCLEB, UCL-LSHTM-Edinburgh-Bristol consortium | kexin type-9 | PCSK9, proprotein convertase subtilisin | CTCF, CTC-binding factor | Medicin och hälsovetenskap
Journal Article
International journal of cardiology, ISSN 0167-5273, 2016, Volume 222, pp. 51 - 56
Cardiovascular | Primary care | LDL-C attainment | Dyslipidemia | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Hypercholesterolemia - blood | Primary Health Care - methods | Primary Health Care - statistics & numerical data | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Risk Factors | Medication Therapy Management - statistics & numerical data | Male | China - epidemiology | Hypercholesterolemia - drug therapy | Dose-Response Relationship, Drug | Medication Therapy Management - organization & administration | Lipid Metabolism - drug effects | Cardiovascular Diseases - epidemiology | Cholesterol, LDL - blood | Female | Aged | Anticholesteremic Agents - classification | Anticholesteremic Agents - pharmacology | Hypercholesterolemia - epidemiology | Needs Assessment | Low density lipoproteins | Cholesterol | Hypercholesterolemia | Hospitals | Analysis | Statins | Index Medicus
Journal Article
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Full Text
Low-density lipoprotein cholesterol in a global cohort of 57,885 statin-treated patients
Atherosclerosis, ISSN 0021-9150, 2016, Volume 255, pp. 200 - 209
Cardiovascular | Treatment targets | Low-density lipoprotein cholesterol (LDL-C) | Statins | Dyslipidemia | Cardiovascular disease (CVD) | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Dyslipidemias - drug therapy | Prevalence | Cross-Sectional Studies | Risk Assessment | Comorbidity | Down-Regulation | Humans | Middle Aged | Risk Factors | Male | Treatment Outcome | Biomarkers - blood | Dyslipidemias - blood | Dyslipidemias - epidemiology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Healthcare Disparities | Cholesterol, LDL - blood | Female | Aged | Dyslipidemias - diagnosis | Medical colleges | Low density lipoproteins | Cardiology | Medicine, Preventive | Cholesterol | Preventive health services | Index Medicus
Journal Article
Circulation: Cardiovascular Genetics, ISSN 0016-6731, 08/2009, Volume 2, Issue 4, pp. 354 - 361
PCSK9 | LDL-C | Genetic variant | Longitudinal study | Words | Cardiac & Cardiovascular Systems | Genetics & Heredity | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Humans | Middle Aged | Risk Factors | Genotype | Male | Apolipoproteins E - genetics | Adolescent | Alleles | Coronary Artery Disease - genetics | Serine Endopeptidases - genetics | Adult | Cholesterol, LDL - blood | Female | Polymorphism, Single Nucleotide | Mutation | Proprotein Convertases | Longitudinal Studies | Amino Acid Substitution | Proprotein Convertase 9 | Index Medicus
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2010, Volume 56, Issue 8, pp. 630 - 636
Adult Treatment Panel | LDL-C | ATP | low-density lipoprotein cholesterol | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Heart | Biological and medical sciences | Medical sciences | Coronary heart disease | Coronary Disease - blood | Risk Assessment | Humans | Risk Factors | Coronary Artery Disease - prevention & control | Ultrasonography, Interventional | Male | Reference Values | Coronary Artery Disease - diagnostic imaging | Coronary Disease - prevention & control | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Adult | Cholesterol, LDL - blood | Practice Guidelines as Topic | Heart attacks | Mortality | Clinical trials | Cardiovascular disease | Mammals | Low density lipoprotein | Cholesterol | Morbidity | Disease prevention | Generic drugs | Ultrasonic imaging | Atherosclerosis | Population | Age | Index Medicus | Abridged Index Medicus
Journal Article
Journal of clinical lipidology, ISSN 1933-2874, 2015, Volume 10, Issue 3, pp. 472 - 489
Cardiovascular | LDL-C | Mortality | Cardiovascular disease | Risk | Epidemiology | Lipid-lowering therapy | Morbidity | Guidelines | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Life Style | Cardiovascular Diseases - metabolism | Cardiovascular Diseases - drug therapy | Humans | Evidence-Based Medicine | Anticholesteremic Agents - adverse effects | Animals | Anticholesteremic Agents - therapeutic use | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Cholesterol, LDL - metabolism | Anticholesteremic Agents - pharmacology | Index Medicus
Journal Article