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ledgf/p75 (229) 229
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European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2019, Volume 182, p. 111617
A number of compounds targeting different processes of the Human Immunodeficiency Virus type 1 (HIV-1) life cycle have been developed in the continuing fight... 
HIV-1 | Integrase | Coumarin derivatives | RNase H | LEDGF/p75 cellular cofactor | Dual inhibitors
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 02/2019, Volume 62, Issue 3, pp. 1348 - 1361
A series of 5,6,7,8-tetrahydro-1,6-naphthyridine derivatives targeting the allosteric lens-epithelium-derived growth-factor-p75 (LEDGF/p75)-binding site on... 
BI 224436 | CHEMISTRY, MEDICINAL | RALTEGRAVIR | HIV-1 INTEGRASE | ACIDS | NCINI | RESISTANCE | LEDGF/P75 | INTEGRASE INHIBITOR | ALLOSTERIC INHIBITORS | DISCOVERY
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 05/2019, Volume 47, Issue 9, pp. 4663 - 4683
Abstract Cleavage factor I mammalian (CFIm) complex, composed of cleavage and polyadenylation specificity factor 5 (CPSF5) and serine/arginine-like protein... 
CLEAVAGE FACTOR-I | SPLICING FACTORS | RNA-BINDING | COMPLEX | LOCALIZATION SIGNAL | HIV-1 INTEGRATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RS DOMAIN | ACINUS | LEDGF/P75 | IDENTIFICATION | Molecular Biology
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 06/2010, Volume 6, Issue 6, pp. 442 - 448
Journal Article
Journal Article
Blood, ISSN 0006-4971, 01/2018, Volume 131, Issue 1, pp. 95 - 107
Mixed lineage leukemia (MLL) represents a genetically distinct and aggressive subset of human acute leukemia carrying chromosomal translocations of the MLL... 
GROWTH-FACTOR LEDGF/P75 | DIFFERENTIAL EXPRESSION | INHIBITION | INTEGRATION | MENIN | THERAPEUTIC TARGET | BONE-MARROW-CELLS | HEMATOLOGY | MIXED-LINEAGE LEUKEMIA | FUSION PROTEINS | HOMEOBOX GENES | Hematopoiesis and Stem Cells
Journal Article
Journal of Immunological Methods, ISSN 0022-1759, 10/2018, Volume 461, pp. 110 - 116
Anti-DFS70 antibodies have been recently included in a new testing algorithm for patients with suspicion of connective tissue diseases (CTDs). This algorithm... 
HEP-2 CELLS | AUTOIMMUNE RHEUMATIC-DISEASES | PATTERN | SPECIFICITY | RECOMMENDATIONS | BIOCHEMICAL RESEARCH METHODS | CLASSIFICATION | POSITIVE HEALTHY-INDIVIDUALS | LEDGF/P75 | IMMUNOLOGY | INDIRECT IMMUNOFLUORESCENCE | ANTINUCLEAR AUTOANTIBODIES | Autoimmunity | Medical records | Algorithms | Autoantibodies | Analysis | Methods
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 21, pp. 8690 - 8695
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 04/2019, Volume 47, Issue 7, pp. 3607 - 3618
Abstract The integration of the retroviral genome into the chromatin of the infected cell is catalysed by the integrase (IN)*viral DNA complex (intasome). This... 
NMR-SPECTROSCOPY | DNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ASSIGNMENT | LEDGF/P75 | PROTEINS | RETROVIRAL INTEGRATION | Life Sciences | Biomolecules | Biochemistry, Molecular Biology | Nucleic Acid Enzymes
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2012, Volume 287, Issue 20, pp. 16801 - 16811
Journal Article